【Advance online publication】 Knockout of the Atg5 gene essential for the formation of autophagosomes results in abnormality of the endoplasmic reticulum in insulin-secreting MIN6 cells. From Kazutoshi Mori Lab. www.jstage.jst.go.jp/article/csf/...

CSF publishes its articles through J‑Stage, and we receive monthly access reports. Look at the sharp increase in access from Vietnam. In February and March 2026, Vietnam ranked third—following the United States and China. CSF is looking forward to papers from Vietnam! www.jscb.gr.jp/csf/en/

【Publication in CSF】　DNA replication was implicated in a ts-mutant exhibiting nuclear elongation. Nuclear enlargement in other mutants was accompanied by increased DNA damage and an abnormal nucleus. From Dr. Kimihiko Sugaya Associate editor: Miho Ohsugi www.jstage.jst.go.jp/article/csf/...

SAVE THE DATE - our next DGZ International Meeting will take place March 14-17,2027, in Bonn, Germany. Stay tuned!

Join us next Tuesday for the next @dgz.bsky.social workshop on #trafficking and EVs! Spread the word please!

📢 Registration is still open for the 28th Annual Meeting of the Club Exocytose–Endocytose! Join us for exciting discussions on membrane trafficking! 📝 Submit your abstract by April 15 ✅ Register by April 30 🔗 Register here: exoendo.org/en/evenement... 📅 May 27–29, 2026 at Aussois (France)

CALLING PHDs AND POSTDOCS! Apply for the 20th FEBS/EMBO summer school on Membranes lipids & proteins in organelle biogenesis! Spend a glorious week with leaders in the field on the beautiful island of Spetses in Greece this May. Registration: spetses2026.sites.uu.nl @embo.org @febspress.bsky.social

【Publication in CSF】This paper describes that Rab30 is a novel target of TBC1D22B and involved in tubular endosome formation in cooperation with BICD2 and KIF5B. From Mitsunori Fukuda Lab., Tohoku Univ., Associate Editor: Akihiro Harada www.jstage.jst.go.jp/article/csf/...

【Publication】 Tumor endothelial cells highly express miR-199a-3p, which promotes their proliferation, migration, and invasion while reducing their adhesion to the extracellular matrix by downregulating the tetraspanin CD151.　From Kyoko Hida Lab, Hokkaido Univ. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】Highly brain-metastatic melanoma cells on a soft extracellular matrix showed low-expression of a proliferation-inhibitor EGR1. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】A member of the TRIM-NHL protein family, Mei-P26 is essential for initiating meiosis in the Drosophila male germline; its loss leads to failure of Cdk1 activation. www.jstage.jst.go.jp/article/csf/...

High cholesterol and increased CAV1 expression promotes stem-like characteristics in glioma spheroids. Reduction of cholesterol hampers hedgehog signaling and provokes expression of epigenetics modifiers causing epigenetic silencing of CAV1 impacting loss of stem-like phenotypes.

【Publication in CSF】 The first paper in CSF from INDIA! J-STAGE Articles - Cholesterol in glioblastoma: Impaired Hh signaling enhances epigenetic modifiers and decreases CAV1 doi.org/10.1247/csf....

【Publication in CSF】 The first paper in CSF from INDIA! J-STAGE Articles - Cholesterol in glioblastoma: Impaired Hh signaling enhances epigenetic modifiers and decreases CAV1 doi.org/10.1247/csf....

【Publiction in CSF】This review article provides an overview of recent advances in multiplex live imaging technologies for dissecting the interplay of signaling dynamics in research fields such as cancer biology. Review from Dr Toru Hiratsuka www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】　This paper reports the identification of transcription factors KLF2 and KLF4 responsible for transcriptional induction of proteoglycan-type glycosylation enzymes during Golgi stress.　From Hiderou Yoshida Lab. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】 This paper shows the functional significance of the increased release of primary cilia-derived extracellular vesicles observed in pancreatic cancer cells proliferating in a solitary condition. From Ikegami Lab, Hiroshima Univ., Japan www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】　From Sei Yoshida Lab, China:　This paper demonstrates that Flot1 participates in the activation of mTORC1 via macropinosomes in podocytes. Depletion of Flot1 attenuates macropinosome-dependent mTORC1 activation in podocytes www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】　This paper demonstrates that force-dependent binding of vinculin to α-catenin promotes rapid adherens junction formation.. From Yonemura Lab Tokushima Univ. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】　This paper reveals that stress granules suppress cell death by regulating magnesium ion homeostasis.　From Shimizu Lab Science Tokyo www.jstage.jst.go.jp/article/csf/...

From Maeshima Lab　@kazu-maeshima.bsky.social @masaashimazoe.bsky.social

【Publication in CSF】　This shows at the single-nucleosome level that the physical behavior of chromatin is reorganized over time during transformation.　www.jstage.jst.go.jp/article/csf/...

My student Aoi Otsuka ’s PhD work is now officially published @csf-jscb.bsky.social! 🔬 Single-nucleosome imaging uncovers biphasic local chromatin dynamics in an oncogene-inducible human carcinogenesis model (1–3 d: same, 5–7 d: ↑, back by week 4). Congrats! www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】 This paper reviews the role of the S100A11 protein, a member of the S100 protein family with diverse functions, and highlights its emerging role as a mechanosensitive regulator of focal adhesion dynamics. doi.org/10.1247/csf....

【Publication in CSF】 - Structural truncation of IL-1R2 enhances the anti-inflammatory activity of HeLa cells doi.org/10.1247/csf....

My PhD students Aoi Otsuka @masaashimazoe.bsky.social et al. published @csf-jscb.bsky.social 🎉 Single-nucleosome imaging in an oncogene-inducible human carcinogenesis model shows biphasic chromatin dynamics (1–3 d same; 5–7 d ↑; back by week 4). Congrats! 👉 doi.org/10.1247/csf....

【Publication in CSF】　Context-dependent interactions among afadin, ZO-1, and actin filaments. This paper shows how afadin and ZO-1, two actin-binding scaffold proteins, interact with each other in non-epithelial cells that lack tight and adherens junctions. www.jstage.jst.go.jp/article/csf/...

Submit to CSF!

【Publication in CSF】　This paper demonstrates a potential non-diffusible factor that induces region-specific gastrulation during early embryogenesis. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】 This paper reports visualization of PE-dependent phospholipid dynamics and phospholipid transport from the vacuole to endosomes using the fluorescent phospholipid probe R18. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】 This paper shows a deep learning model for accurate segmentation of overlapping biological membranes, applied to analyze prospore membrane morphology in budding yeast sporulation. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】This paper visualized supersulfides in skin keratinocytes and elucidated their role in cell migration. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】　This paper shows how the IFT-B complex (composed of 16 subunits), which constitutes the intraflagellar transport (IFT) machinery, is assembled at the mother centriole. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】This paper reports the development of a tool that controls the activity of the tumor suppressor protein p53 using light, demonstrating that it can induce cell cycle arrest and cell death. www.jstage.jst.go.jp/article/csf/...

【Publication in Advance】 Dr Kazuhisa Nakayama@Kyoto Univ. J-STAGE Articles - Assembly and mother centriole recruitment of IFT-B subcomplexes to form IFT-B holocomplex doi.org/10.1247/csf....

【Publication in CSF】 This paper highlights the function of human STING variants and their associated diseases. J-STAGE Articles - Cell biological insights into human STING variants doi.org/10.1247/csf....

【Publication in CSF】 This paper shows that ER-localized molecular chaperones, BiP, GRP94, calreticulin, and calnexin, contribute development of the notochord in medaka fish. doi.org/10.1247/csf....

【Publication in CSF】 doi.org/10.1247/csf.... This paper shows a new high-throughput assay system to quantify the degradation of an innate immune protein STING.

【Publication in Advance】 A quantitative method to monitor STING degradation with dual-luciferase reporters. 東北大学・田口友彦博士の研究室より。 www.lifesci.tohoku.ac.jp/research/fie... doi.org/10.1247/csf....

【Publication in CSF】　In this paper, we show that macropinocytosis regulates the Erk pathway to modulate cytokine expression.　From Sei Yoshida Lab, Nankai Univ. www.jstage.jst.go.jp/article/csf/...

【Publication in CSF】This paper reports on how sprouting endothelial cells migrate toward the target vessels during the formation of the cerebral capillary network. www.jstage.jst.go.jp/article/csf/...

Save the date! Cell Bio 2025, the joint ASCB | EMBO meeting, will take place in Philadelphia, US, 6 – 10 December 2025: www.ascb.org/cellbio2025/ #CellBio2025 @ascbiology.bsky.social 🧪

【New Publication in CSF】　This paper comprehensively reviews the fluorescent sensors that visualize cell cycle regulatory CDK activities in real-time within living cells. doi.org/10.1247/csf....

Joint Meeting of JSCB 77th & JSDB 58th Japan Society for Cell Biology & Japanese Society of Developmental Biologists July 16-18, 2025, Nagoya Abstract deadline: April 10 pub.confit.atlas.jp/en/event/jsc...

「長年、「endoplasmic reticulum（ER）」の訳語として「小胞体」という名称が 使用されてきましたが、実際の細胞内の形態（シートおよびチューブ状構造）と大きく異なるため、教育や研究の場で誤解が生じています」

「小胞体」の新名称へのパブリックコメントの募集案内です。どなたでも送れます！https://www.jscb.gr.jp/app/uploads/2025/02/publiccomment.html

【Publication in Advance】 Gui & Nakajima from Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute. Beautiful vessels！- Chemokine induces phase transition from non-directional to directional migration during angiogenesis doi.org/10.1247/csf....

From Kazutoshi Mori Lab:　This paper shows that only Tango1L is required for enlargement of COPII vesicles among 2 genes (2 splicing variants each) in medaka fish.　Tango1L but not Tango1S, Tali and cTAGE5 is required for export of type II collagen in medaka fish doi.org/10.1247/csf....

【Publication in Advance】J-STAGE Articles - Macropinocytosis regulates cytokine expression through Erk signaling in LPS-stimulated macrophages doi.org/10.1247/csf....

【Publication in Advance】 Review article by Yuhei Goto@Kyoto Univ. J-STAGE Articles - Capturing CDKs in Action: Live-Cell Biosensors Pioneer the New Frontiers in Cell Cycle Research doi.org/10.1247/csf....