Dear all, I have coined a phrase: To A.Iron Definition: To polish text using AI @academic-chatter.bsky.social

📄Shoutout to our 2019 Research Center awardees at Yale (@pdc-lab.bsky.social, @shawnferguson.bsky.social) for their new publication on the bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage: www.nature.com/articles/s41...

For clear thinking, cultivate passionate indifference. Buddhists call it non-attachment. We all have hopes, desires and ambitions. Non-attachment means acknowledging them, accepting them, and then not inserting them into a process that has nothing to do with you. podcasts.apple.com/us/podcast/n...

Congrats to the Johannes lab! 👏 E MacDonald, @aforrester.bsky.social @cessvala.bsky.social E Dransart, A Akhil Shp, L Leconte, V Chambon, D Ghosh, A Pinet, D Bhatia, B Lombard, D Loew, MShafaq-Zadah, @christianwunder.bsky.social @institutcurie.bsky.social pubmed.ncbi.nlm.nih.gov/39984654/

📣 We are advertising for a postdoc to join our team at the University of Edinburgh! Our lab studies gene regulatory mechanisms in development, and how genetic changes may impact these processes to alter development and shape human craniofacial form and function 🧬🧪

The 16th ER & Redox club meeting ends. THANK YOU to co-organiser @fenech-lab.bsky.social & to everyone for outstanding presentations, discussions, posters and fun over the last 4 days in Namur. Huge thanks to @unamur.bsky.social @biologists.bsky.social @febspress.bsky.social for support and funding!

A terrific perspective from Vivek Malhotra @naturecomms.bsky.social on the fundamental importance of pathways and mechanisms by which cells secrete proteins, ensuring their delivery in the correct quantities and at the appropriate times. Interesting section on unanswered questions. rdcu.be/ecb2B

Lab manager position open. Does the idea of helping a busy structural cell biology and biochemistry-based drug discovery lab stave off chaos appeal to you? Apply now at tinyurl.com/4dsvpwbw

Just a week left to apply for this postdoc position in my lab in Oxford.

... and soon the structural glycoswitch: www.biorxiv.org/content/10.1...

I'm thrilled that our paper is now online: www.nature.com/articles/s41... describing an elegant pH-triggered CIE. Thanks to everyone who made it an exciting and successful project @ewanmacdonald.bsky.social @cessvala.bsky.social @christianwunder.bsky.social #fluorescencefriday #microscopymonday

I'm happy to share our review latest review on flotillins! We discuss the recent insights into the structure of these interesting proteins from cyro-EM studies. doi.org/10.1111/boc....

Going Green at the Department of Biology and Faculty of Medicine at the University of Namur! We've worked on it for a year, now it's time to go big 😁💚🔬 The initiative seems to be making some waves and it's great to see som much enthusiasm! @fsilvestrelab.bsky.social #sustainability #GreenLab

ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬 The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy www.biorxiv.org/content/10.1...

Inscriptions for the 27th annual meeting of the Club Exo-Endo are opened. Please register on exoendo.org !!

Check it out, powerful new method for optical imaging of the live ECM, from @hhmijanelia.bsky.social Group Leader Kayvon Pedram #proudofalumni #glycotime www.nature.com/articles/s41...

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that. www.biorxiv.org/content/10.1...

Our plasmids for editing are now on @addgene.bsky.social! www.addgene.org/Francesca_Bo... I promise you a detailed protocol on how to use them is coming very very soon! Currently proofreading :)

Excited to see work led by @autophazeke.bsky.social, @minghaochen.bsky.social, Thanh Nguyen, and Ainara Claveras out in @science.org today, the culmination of a 15-year project to understand structurally how the synthesis of the critical lipid of autophagy, PI3P, is regulated. tinyurl.com/ywvjh8u4

We're happy to announce the launch of the new website of the Club Exo-endo. From the site, you can register for the annual meeting, register as a new member, advertise a position, apply for the thesis prize or post your latest publication. Please visit us at exoendo.org and make it interactive !

The #MembraneTrafficking seminar series is back this Thursday, and we are very happy to start the 2025 season with two talks by early career scientists: Adam Krahn from the Glick Lab at University of Chicago and @jkefauver.bsky.social at CINN-CSIC, Spain.

Just wrapped up an incredible meeting in Innsbruck with an amazing group of membrane traffickERs. The intimate, congenial setting fostered open, positive discussions and constructive critiques—intense and inspiring. Huge thanks to Hesso @hessofarhan.bsky.social for organising!

It’s been a gEReat few days with a wondERful group! A million thanks to @hessofarhan.bsky.social for organising it. I’m already excited about the next one! #It’snotanERGIC…isitanERGIC?

The first supper before our ERES meeting

Trafficking myself to @i-med.ac.at for a few days organised by @hessofarhan.bsky.social to witness classic ERES behaviour and a concentration of ERES fans and experts. Nice journey so far with trafficking chaperone @ishier.bsky.social

Exciting news! #MembraneTrafficking online seminars with @felixmendu.bsky.social @franbottanelli.bsky.social and me are back! Check the spectacular Jan-April 2025 lineup. Details (Zoom links, calendar invites) on the mailing list, Slack group & website: felixcampelo.wixsite.com/membranetraf...

This Thursday we are back with the #MembraneTrafficking seminars, with two exciting talks! Louise Fougère (@yohannboutte.bsky.social lab) will talk about #ER export in plants, and Jennifer Lippincott-Schwartz about #lysosome engulfment of ERES under starvation. Join us Thursday at 5pm CET!

📢 Announcing the Membrane Trafficker Starter Pack! This list highlights researchers advancing our understanding of membrane trafficking pathways. This is just a beginning—help expand the list! go.bsky.app/J9GvL3S

It's time to apply! I'm very excited to be part of this amazing line up. Looking forward to the discussions and new people, and to seeing you there!

I'm very happy to share a review that I've written with Claire Robinson, illustrated by Aislinn Duggan (both of University College Dublin) on ER exit in physiology and disease. www.frontiersin.org/articles/10....

Congress of multiple dimers is needed for cross-phosphorylation of IRE1α and its RNase activity https://www.biorxiv.org/content/10.1101/2023.12.18.572154v1

An amazing opportunity to work with one of the most fantastic young PIs. Get in touch with him!

The membrane curvature inducing REEP1 proteins generate a novel ER-derived vesicular compartment https://www.biorxiv.org/content/10.1101/2023.12.19.572386v1

🚨 We have a new preprint out: www.biorxiv.org/content/10.1... 📃 Proudly introducing the next chapter of our collaboration with Stéphane Vassilopoulos - still looking at axons, now focusing on clathrin-coated pits and endocytosis!

Looking festive! A Christmas pilgrimage to visit Christian De Duve’s electron microscope at the de Duve Institute in Belgium. Hand me the booking sheet!!

The JCS “Diversity and Evolution in Cell Biology" conference is accepting applications! Spain, 2024. Please spread the word! 🧪https://www.biologists.com/meetings/jcsevocellbio24/

Excellent piece by El Pais (in English, usefully for me) about the explosive growth of scientific publishers of dubious scientific rigour - to put it politely. We have all seen the signs, but the scale is awesome: have you published 418 papers this year, anyone? Someone has...