Felix Campelo
@felixmendu.bsky.social
📤 488
📥 585
📝 87
Lorem ipsum
pinned post!
Announcing a new
@embo.org
Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at
@icfo.eu
(Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏
#EMBOmechanobio
meetings.embo.org/event/26-org...
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Intracellular mechanics and organelle mechanobiology
Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…
https://meetings.embo.org/event/26-organelle-mechanobiology
7 months ago
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Join us this Thursday (Jan 29) at 5pm CET for the first
#MembraneTrafficking
seminars of 2026, featuring two outstanding scientists, Giovanni D'Angelo (EPFL) and Sean Munro (
@cellbiol-mrclmb.bsky.social
), and the shared topic of protein trafficking, retention & sorting at the
#Golgi
🥞
about 13 hours ago
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Two PhD positions just opened in the Gallego lab at our department
@melisupf.bsky.social
@upf.edu
@prbb.org
!
#MembraneTrafficking
in cryo-tolerant systems, with wet lab and computational projects available. Come do cool (and cold 😉) science with Oriol in Barcelona!
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1 day ago
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Felix Campelo
Benoit Ladoux
1 day ago
Happy to highlight our collaborative work from our
@ijmonod.bsky.social
team with
@destriano.bsky.social
, B. Goyeau and M. Chabanon. Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity. Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
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Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion | PNAS
Intracellular transport of macromolecules is crucial for the proper functioning of most cellular processes. Although intracellular crowding is know...
https://www.pnas.org/doi/10.1073/pnas.2519599123
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Felix Campelo
Levental Lab
3 days ago
Excited to share a new story that transformed how we think about membrane domains in the ER!
rdcu.be/eR7Cn
ER exit sites mediated by the COPII adaptor sec24D selectively recruit lipid raft-preferencing proteins for rapid ER export Wondering what’s so new and exciting? Skytorial below! 1/9
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ER exit sites mediated by the COPII adaptor sec24D selectively recruit lipid raft-preferring proteins for rapid ER export
Nature Communications - Through synchronized cargo traffic experiments, the authors explore the role of raft partitioning in ER efflux. Raft-preferring cargos show specific preferences for ER exit...
https://rdcu.be/eR7Cn
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reposted by
Felix Campelo
Ishier Raote
4 days ago
I’ll soon share a call for a postdoc at Institut Jacques Monod (Paris) on fundamental mechanisms of membrane traffic and protein/collagen secretion in health and disease. Please get in touch if interested.
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Felix Campelo
FocalPlane
5 days ago
🔬🔦 Imaging spotlight on FocalPlane
@janakroll.bsky.social
and colleagues highlight their research visualising synaptic vesicle fusion using cryo-ET combined with plunge freezing and optogenetics.
focalplane.biologists.com/2026/01/21/i...
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Imaging spotlight: visualising synaptic vesicle fusion by cryo-ET - FocalPlane
Imaging spotlight: visualising synaptic vesicle fusion by cryo-ET - News
https://focalplane.biologists.com/2026/01/21/imaging-spotlight-visualising-synaptic-vesicle-fusion-by-cryo-et/
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Felix Campelo
Gallego Lab
11 days ago
0/10 🥳 our
#exocyst
paper out in
@cp-cell.bsky.social
, led by Marta, Sebas &
@sasmeek.bsky.social
in collab with
@jonasries.bsky.social
,
@cmanzo.bsky.social
& Castaño-Díez labs
#Quantitative_Cell_Biology
Continuum architecture dynamics of vesicle tethering in exocytosis
www.cell.com/cell/fulltex...
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Continuum architecture dynamics of vesicle tethering in exocytosis
Data from complementary imaging techniques were integrated into a model that resolves the dynamic exocyst ensemble and membrane architecture during exocytosis, an essential cellular pathway. Sec18 med...
https://www.cell.com/cell/fulltext/S0092-8674%2825%2901374-1
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Cell - a Cell Press journal
11 days ago
Now online! Continuum architecture dynamics of vesicle tethering in exocytosis
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Continuum architecture dynamics of vesicle tethering in exocytosis
Data from complementary imaging techniques were integrated into a model that resolves the dynamic exocyst ensemble and membrane architecture during exocytosis, an essential cellular pathway. Sec18 mediates the rate of exocytosis by disassembling the exocyst higher-order structure after vesicle fusion.
http://dlvr.it/TQNlf0
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Felix Campelo
Fran Bottanelli
14 days ago
Happy that we could contribute to this exciting paper from the
@spanglab.bsky.social
!
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Felix Campelo
Ishier Raote
14 days ago
Exciting preprint from
@franbottanelli.bsky.social
and
@annespang.bsky.social
! ARF-1 regulates FERARI-mediated endosomal kiss-and-run recycling by controlling selective cargo loading into vesicles. ARF-1 Coordinates Cargo Sorting at FERARI Endosomal Recycling Hubs
www.biorxiv.org/content/10.6...
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Felix Campelo
Ishier Raote
13 days ago
Exciting preprint from
@felixmendu.bsky.social
and Yuichi Wakana! A TGN carrier whose budding is driven by ER–Golgi lipid transfer, PKD activity, and a caveolin-based oligomeric coat! A PKD-caveolin axis drives secretory carrier biogenesis at the TGN
www.biorxiv.org/content/10.6...
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Congratulations Laura, Verena, and everyone else involved!!
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13 days ago
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Felix Campelo
Fundació Catalana per a la Recerca i la Innovació
about 1 month ago
⏰ Última setmana per inscriure’s a
#científiques
2026! Si ets investigadora o formes part d’un centre educatiu, encara hi ets a temps. Uneix-te a la iniciativa que ja ha portat més de 600 científiques a les aules i ha implicat més de 500 centres. 📆Termini: 22/12 🔗https://tuit.cat/TSJhl
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Felix Campelo
Raimon Sunyer
about 1 month ago
Talin didn’t evolve for integrins... integrins evolved for talin 🤯 pN force coupling via talin is ancient, conserved from amoebae to humans; signaling came later. Read this amazing paper here 👇🏽
www.nature.com/articles/s41...
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Talin force coupling underlies eukaryotic cell-substrate adhesion - Nature Communications
Talin is a well-known regulator of cell adhesion and intracellular force transmission in animals. Here, the authors demonstrate that talin’s mechanical function is evolutionarily conserved and already established in unicellular eukaryotes.
https://www.nature.com/articles/s41467-025-67354-8
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Felix Campelo
Jana Kroll
about 2 months ago
❄️🔬⏱️ I am excited to share that our study „Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons” has been published in Nature Communications
www.nature.com/articles/s41...
👇 Short summary of our key findings (1/8)
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Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons - Nature Communications
Synaptic vesicle fusion is essential for neuronal communication, yet its nanoscale sequence has not been directly confirmed. Here, the authors use timed in situ cryo-electron tomography to visualize t...
https://www.nature.com/articles/s41467-025-67291-6
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Felix Campelo
Liz Miller
about 2 months ago
My excellent collaborator, Giulia Zanetti, is advertising for a post-doc to work on our shared MRC grant. Please consider applying to this great lab with a supportive mentor to do some exciting structural biology.
www.ucl.ac.uk/work-at-ucl/...
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UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs/details?nPostingId=16553&nPostingTargetId=39994&id=Q1KFK026203F3VBQBLO8M8M07&LG=UK&languageSelect=UK&mask=ext
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reposted by
Felix Campelo
Fran Bottanelli
about 2 months ago
#membrane
seminars are back this THURSDAY for a super session with
@dr-downes.bsky.social
from the
@giuliazanetti.bsky.social
lab and Xin Zhou from the Ikonen lab!
@felixmendu.bsky.social
@ishier.bsky.social
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Felix Campelo
Javier Espadas
about 2 months ago
New preprint from the lab!!🎉 We show that Asgard archaea ESCRT-III proteins can trigger membrane fission and reveal its molecular mechanism, offering clues to how these cells may have built internal compartments. But do these organisms even have these compartments?
www.biorxiv.org/content/10.1...
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Molecular basis for cellular compartmentalization by an ancient membrane fission mechanism
The emergence of cell compartmentalization depends on membrane fission to create the endomembrane compartments. In eukaryotes, membrane fission is commonly executed by ESCRT-III, a protein complex con...
https://www.biorxiv.org/content/10.1101/2025.11.28.690958v1
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Last week to submit an abstract to the "Intracellular mechanics and organelle mechanobiology" EMBO workshop
#EMBOmechanobio
👇
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about 2 months ago
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Felix Campelo
Ishier Raote
2 months ago
Nice paper from
@leventallab.bsky.social
suggess lipid-driven domains organise cargo and trafficking machinery at ERES to sort and export transmembrane proteins. ER exit sites mediated by the COPII adaptor sec24D selectively recruit lipid raft-preferring proteins for rapid ER export.
rdcu.be/eR8jj
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ER exit sites mediated by the COPII adaptor sec24D selectively recruit lipid raft-preferring proteins for rapid ER export
Nature Communications - Through synchronized cargo traffic experiments, the authors explore the role of raft partitioning in ER efflux. Raft-preferring cargos show specific preferences for ER exit...
https://rdcu.be/eR8jj
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Felix Campelo
Philip Ball
2 months ago
It was fun, and a great honour, to receive this award in Barcelona last night. I'm speaking tonight about quantum matters for the City Biennal.
www.biennalciutaticiencia.barcelona/en/activitie...
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https://www.biennalciutaticiencia.barcelona/en/activities/nat-prize-barcelona-museum-natural-sciences
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Felix Campelo
Nature Reviews Molecular Cell Biology
3 months ago
ICYMI: New Online! Mechanistic insights into cargo sorting and export from the Golgi apparatus
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Mechanistic insights into cargo sorting and export from the Golgi apparatus
Nature Reviews Molecular Cell Biology, Published online: 10 November 2025; doi:10.1038/s41580-025-00907-3Protein and lipid cargoes are modified and sorted in the Golgi apparatus and packaged for delivery to diverse cellular destinations at the trans-Golgi network (TGN). This Review discusses recent insights into Golgi transport mechanisms and carrier biogenesis at the TGN.
https://bit.ly/4nRQTiI
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Felix Campelo
Prasanna Satpute-Krishnan
3 months ago
Check out our
@ascbiology.bsky.social
#CellBio2025
Minisymposium on ER Homeostasis. With THIS speaker lineup, this event will be as dynamic, transformative and productive as the ER itself! So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
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Join us at
@icfo.eu
in Barcelona next February for the 1st
@embo.org
Workshop on "Intracellular mechanics and organelle mechanobiology". I am convinced it will be very interesting! We have extended the abstract submission deadline to December 8, so no excuses :)
#EMBOmechanobio
add a skeleton here at some point
3 months ago
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reposted by
Felix Campelo
Announcing a new
@embo.org
Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at
@icfo.eu
(Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏
#EMBOmechanobio
meetings.embo.org/event/26-org...
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Intracellular mechanics and organelle mechanobiology
Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…
https://meetings.embo.org/event/26-organelle-mechanobiology
7 months ago
1
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reposted by
Felix Campelo
The Company of Biologists
4 months ago
Registration is now open to attend Journal of Cell Science's meeting on Imaging Cell Dynamics, organised by Francesca Bottanelli, Guillaume Jacquemet, Michael Way and Giulia Zanetti. Find out more:
biologists.com/meetings/jcs...
#JCSimaging
#Microscopy
#Microscope
#Imaging
#Cells
#CellScience
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Felix Campelo
Ishier Raote
3 months ago
#MembraneTraffickers
! Our next online seminar is this Thursday, Nov 6 at 5 PM CEST! We’ll hear from
@agatawitkowska.bsky.social
on mechanical control of neurotransmission and
@abdourachidthiam.bsky.social
on lipid storage mechanisms in health and disease. Spread the word and join the discussion!
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Felix Campelo
Nadia Halidi
3 months ago
I have two open positions @ALMU
@crg.eu
: 1. Imaging Scientist (permanent position. Deadline 11th Nov.)
recruitment.crg.eu/content/jobs...
2. Entry-Level Imaging Scientist (12 months fixed-term position. Deadline 18th Nov.)
recruitment.crg.eu/content/jobs...
Reposts appreciated.
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Felix Campelo
UPF Medicine and Life Sciences
3 months ago
Another great opportunity to join us! 👏
#PostDocPosition
#AcademicJobs
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Interested in intracellular organization and membrane trafficking? 🥞 Join us at
@melisupf.bsky.social
in Barcelona! We’re looking for postdocs to apply for a Juan de la Cierva fellowship (PhD between Jan’24–Dec ’25). If you’d like to work with us, get in touch!
www.aei.gob.es/en/announcem...
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Ayudas para contratos Juan de la Cierva 2025 | Agencia Estatal de Investigación
Las ayudas Juan de la Cierva tienen como finalidad fomentar la incorporación de jóvenes, en posesión del grado de doctor, con objeto de que completen su formación investigadora postdoctoral en centros...
https://www.aei.gob.es/en/announcements/announcements-finder/ayudas-contratos-juan-cierva-2025
3 months ago
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Felix Campelo
Monica Bettencourt-Dias
3 months ago
📣 We are moving to Barcelona to join the amazing
@crg.eu
and explore how centrosomes & cilia work, evolve & respond to the environment. We are looking for PhD students
www.crg.eu/en/content/t...
Postdocs
gimm.pt/jobs/postdoc...
Other calls to open, also for an experienced lab manager. Get in touch!
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Hiren Joshi
3 months ago
Reminder: our postdoc and PhD positions are still open. We work across different areas (wet and dry lab), but I am especially after people with a computational biology, bioinformatics, pytorch whisperer kind of background. Protein design and OpenFold/AF also counts.
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Calling all
#Membrane
enthusiasts! Our
#MembraneTrafficking
online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26. The first talks are already next Thursday (Nov 6, 5pm CET) with
@agatawitkowska.bsky.social
and
@abdourachidthiam.bsky.social
!
3 months ago
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Felix Campelo
Manuel Irimia
3 months ago
🚨🚨🚨 Two super well-funded PhD grants from our MSCA Doctoral Network
@evomg-dn.bsky.social
at our lab at
@melisupf.bsky.social
,
@crg.eu
and the
@evomg-bcn.bsky.social
Program. If you're excited about evolution, genomics and biomedical research, this is your DN! 😃 Further info:
www.evomg-dn.eu
and 👇
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EVOMG-DN
EvoMG-DN is a European Doctoral Network funded by the Horizon Europe Marie Skłodowska-Curie Actions (MSCA), composed of 14 beneficiaries and associated partners from both academic and non-academic sectors.
https://www.evomg-dn.eu/
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Felix Campelo
3 months ago
I'm hiring a postdoc! If you're interested in researching mechanisms of 3D tissue morphogenesis and have experience studying cell dynamics and performing quantitative image analysis, consider joining us
@mbisg.bsky.social
!
www.mbi.nus.edu.sg/jobs/seeking...
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https://www.mbi.nus.edu.sg/jobs/seeking-postdoctoral-fellow-in-asst-prof-natalie-dyes-laboratory-at-the-mechanobiology-institute-nus-2/
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Felix Campelo
Luis Bonet-Ponce
4 months ago
🚨 We’re hiring a postdoc! 🚨 Interested in lysosomes, Parkinson’s disease, cell biology, microscopy — or all of the above? Come work with us at the Bonet-Ponce Lab! Reach out directly:
[email protected]
Learn more:
bonetponcelab.com
Let’s chat!
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Felix Campelo
Cristina Pujades
4 months ago
We are hiring ! Interested in understanding how neuronal cell diversity arises? Come and join us
@upf.edu
for a
#PhD
#FPI
fellowship
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Felix Campelo
preLights
4 months ago
Happy October 1st! A good time to share another
#CellBio
#preprint
reading list put together by a team of preLighters:
@sristi.bsky.social
, Matthew Davies,
@vibhasingh.bsky.social
,
@fadelvalle.bsky.social
& Barbora Knotkova. Check out their picks ⬇️👀
prelights.biologists.com/prelists/sep...
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September in preprints – Cell biology edition - preLights
https://prelights.biologists.com/prelists/september-in-preprints-cell-biology-edition/
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Felix Campelo
Markus Deserno
4 months ago
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪 Interfolio link:
apply.interfolio.com/174360
PLEASE, share widely across the blue skies! Let me briefly explain what we're looking for: 1/10
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Felix Campelo
Manuel Thery
4 months ago
intracellular mechanics ! in Barcelona in February (when its freezing anywherelse) !
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Felix Campelo
Lisa Heinke
4 months ago
Check out this new Roadmap, a fantastic team effort by a consortium of ER researchers. Glad we could provide the space for this synthesis, which came out of discussions at a fruitful meeting, see below:
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Felix Campelo
Hesso Farhan
4 months ago
It was a great pleasure to work on this paper. What started as a small meeting in January this year resulted in this beautiful piece of work.
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Felix Campelo
Ishier Raote
4 months ago
ER exit sites are dynamic ER subdomains that integrate signals, reshape membranes and steer secretion. Twelve groups in the field came together to map their diversity, regulation, unanswered questions and future directions.
www.nature.com/articles/s41...
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Towards a unified framework for the function of endoplasmic reticulum exit sites - Nature Reviews Molecular Cell Biology
Endoplasmic reticulum exit sites (ERES) are specialized ER subdomains that regulate the export of secreted cargo. This Roadmap explores how ERES integrate biochemical and mechanical signals to coordinate trafficking and proposes a multidisciplinary strategy to investigate their function, including in disease.
https://www.nature.com/articles/s41580-025-00899-0?utm_source=%5Bbluesky%5D&utm_medium=social&utm_campaign=%5Bnrm%5D
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Join us for the first
@embo.org
meeting on Intracellular mechanics and organelle mechanobiology! Registrations are open, submit your abstract by November 14: we have plenty of slots for short talks!
#EMBOMechanobio
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4 months ago
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🧵 I've been meaning to write a
#Skytorial
on our recently posted prepring in which we show evidence that the Golgi 🥞 is a mechanoresponsive organelle. Extracellular mechanical forces also tune Golgi export capacity! 👉
www.biorxiv.org/content/10.1...
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Mechanical forces stimulate Golgi export
Human cells face a wide range of external mechanical stimuli that vary with cell type, state, and pathological conditions. The rapidly growing field of mechanobiology investigates how cells sense and ...
https://www.biorxiv.org/content/10.1101/2025.09.02.673725v1
4 months ago
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This is already This Thursday (25th September)! Join us at the
@focalplane.bsky.social
features
#MembraneTrafficking
for lots of amazing microscopy and interesting membrane biology!
@franbottanelli.bsky.social
@ishier.bsky.social
@biologists.bsky.social
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4 months ago
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Felix Campelo
Rachel Lennon
4 months ago
Check out our latest review on Basement Membranes! Including scaled representation of protein & glycan components 😊
@mcrcellmatrix.bsky.social
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Next Thursday Sept 25 (4-6pm CET) we have our first
#FocalPlaneFeatures
together with our
#membranetrafficking
community! Thanks to all who submitted such exciting abstracts. The final program is out, featuring a keynote by Gillian Griffiths. Register here:
focalplane.biologists.com/2025/09/16/f...
4 months ago
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Felix Campelo
Richard Sever
4 months ago
Lovely to see David Stephens highlighted in 100 years of cell biologists at J. Cell Sci., alongside Linda Amos, Peter Medawar, Juan Bonifacino, and others
journals.biologists.com/jcs/article/...
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‘First Persons’ through the decades – 100 years of notable scientists in Journal of Cell Science
Summary: JCS highlights the lives and careers of 10 notable scientists from around the world who published first author papers in our journal over the last 100 years.
https://journals.biologists.com/jcs/article/138/17/jcs264351/369118/First-Persons-through-the-decades-100-years-of
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eLife
5 months ago
Membrane Biology: Nothing can replace polyunsaturated lipids Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane.
buff.ly/qcLJNUN
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