In @jcb.org, Kim, Parolek, and Burd @yalecellbiology.bsky.social show that depletion of #cholesterol increases #sphingomyelin synthesis as a result of increased coatomer II–mediated endoplasmic reticulum-to-#Golgi #trafficking of #ceramide, the precursor to sphingomyelin. rupress.org/jcb/article/...

Kim, Parolek, and Burd @yalecellbiology.bsky.social show that depletion of #cholesterol increases #sphingomyelin synthesis as a result of increased coatomer II–mediated endoplasmic reticulum-to-#Golgi #trafficking of #ceramide, the precursor to sphingomyelin. rupress.org/jcb/article/...

Submit your latest research to our upcoming special issue: Cell Biology of the Nucleus. This issue is being coordinated by Abby Buchwalter @abbybuch.bsky.social, working alongside Megan King @luskinglab.bsky.social. Deadline: 5 January 2026 journals.biologists.com/jcs/pages/nu...

Congratulations to Amanda Bentley-DeSousa of the Ferguson lab for her paper being selected as one of JCB’s most impactful papers of 2025! @shawnferguson.bsky.social

New research led by Devin Clegg that defines how lysosome swelling and lysosome deacidification evoke distinct routes for LRRK2 activation: doi.org/10.1101/2025...

We were honored to host Dr. Taekjip Ha as part of our seminar series last week! Postdoctoral fellow Avinash Kumar interviewed Dr. Ha about his research career, mentorship, and more. Read the full article here! medicine.yale.edu/news-article...

Lipid scramblases and BLTPs are key to regulate cellular lipid dynamics. Justin Korfhage and I described in-vitro methods to study lipid scrambling by protein insertases and ATG2-mediated lipid transfer on artificial lipid droplets. www.sciencedirect.com/science/chap...

Dr. Phyllis Hanson was recently awarded the Sir Bernard Katz Award for excellence in exocytosis and endocytosis research. Congratulations, @pihanson.bsky.social ! medicine.yale.edu/cellbio/news...

Exciting new work from Xiaolei Su’s lab showing how engineering chimeric antigen receptors (CARs) with intrinsically disordered regions (IDRs) increases the efficacy of CAR-T cell cytotoxicity against cancer cells!

We're hiring new faculty! Looking for talented scientists that are interested in pushing the boundaries of Cell Biology. Please spread the word!

Interested in metabolism? So are we! My lab has been exploring the cell biology of energy metabolism in the nervous system, and we are looking for postdocs. Cool sensors and microscopy, great work environment. Please help me spread the word!

We're still accepting submissions for our next special issue: Cell Biology of the Nucleus Guest edited by @abbybuch.bsky.social and Megan King @luskinglab.bsky.social. Submission deadline: 3 November journals.biologists.com/jcs/pages/nu... #cellbiology #nucleus #notforprofit #freetopublish

Interesting synthetic lethality during mouse development of two bridge-like lipid transfer proteins that are thought to localize in distinct compartments...new work from @pdc-lab.bsky.social in collaboration with @dianekrause.bsky.social: journals.plos.org/plosbiology/...

CRN Team De Camilli reveals a new molecular mechanism that regulates cystine efflux from lysosomes. This work is relevant to #Parkinsons research, as recent studies show JIP4 is downstream of LRRK2. 🔗 Read their #preprint: bit.ly/4l8zCkf ✏️ @shawnferguson.bsky.social @laylanassar.bsky.social

Join us this Thursday for our mini-symposium with the membrane trafficking webinar series Featuring talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and a keynote lecture from Gillian Griffiths @griffithslab.bsky.social. focalplane.biologists.com/2025/09/16/f...

Thanks to Min Wu from Yale Cell Bio for a great talk today about information processing at the immune cell surface in the second edition of our new PEB / QBio seminar series. Yale friends, we hope you join us at future talks in this series, happening on Fridays at 11AM!

Did you know that all nuclear pore complexes (NPCs) are not the same? @luskinglab.bsky.social propose a new hypothesis for how nuclear mechanics may impact the compositional plasticity of NPCs with implications for tissue-specific diseases caused by NPC dysfunction. www.nature.com/articles/s41...

Happy Post Doc Appreciation Week! We are so grateful to all our post docs for the research expertise, leadership, and mentorship they bring to our department! #NPAW2025 #postdocappreciationweek

Next Thursday Sept 25 (4-6pm CET) we have our first #FocalPlaneFeatures together with our #membranetrafficking community! Thanks to all who submitted such exciting abstracts. The final program is out, featuring a keynote by Gillian Griffiths. Register here: focalplane.biologists.com/2025/09/16/f...

@pdc-lab.bsky.social lab does it again - new insight into bridge-like transport proteins - this time as part of the curious CASM pathway. BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM | The EMBO Journal www.embopress.org/doi/full/10....

Registration is open for our Imaging Cell Dynamics meeting. Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti, the meeting will focus on the interface between cell biology and imaging. For more info: www.biologists.com/meetings/jcs...

Learn more about all the 2025 #LaskerAward winners—Dirk Görlich & Steven L. McKnight; Michael J. Welsh, Jesús (Tito) González, & Paul A. Negulescu; Lucy Shapiro 🧪 #Lasker2025 📖: laskerfoundation.org/winners/2025... 👀: laskerfoundation.org/the-2025-las...

ICE and DHS have proposed capping F and J visas at 4 years, threatening international students and postdocs who drive U.S. research. Share your comments to oppose this harmful policy: www.ascb.org/science-poli...

More insight into the ever expanding roles of bridge-like lipid transfer proteins from @pdc-lab.bsky.social ! Multiple interactions recruit BLTP2 to ER-PM contacts to control plasma membrane dynamics url: rupress.org/jcb/article/...

Who knew the ER was under tension? Innovative work from @schliekerlab.bsky.social with help from @berrolab.bsky.social Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation url: rupress.org/jcb/article/...

Check out the latest issue of JCB for new work from @luskinglab.bsky.social - a powerful microscopy tool developed here by the Bewersdorf lab that is providing new views of NPCs. Visualizing nuclear pore complex plasticity with pan-expansion microscopy url: rupress.org/jcb/article-...

We're hiring new faculty! Looking for talented scientists that are interested in pushing the boundaries of Cell Biology. Please spread the word!