A month behind the times, but I wanted to share an update from @emmajays.bsky.social and other co-authors in @riley-research.bsky.social. Our manuscript "Profiling Glycoproteins Enriched by Multinanoparticle Protein Corona" is now published in Analytical Chemistry: pubs.acs.org/doi/abs/10.1...

2025 ended with this paper being accepted by Analytical Chemistry! 😁 Please check out our article in its new home and learn how these multinanoparticle protein coronas grant us a deeper insight into the glycoproteome of different biofluids: pubs.acs.org/doi/10.1021/...

Antibody-lectin chimeras for glyco-immune checkpoint blockade - @jcstark.bsky.social @carolynbertozzi.bskyverified.social go.nature.com/4aRDpk8

A new jump forward in cancer immunotherapy blocking glycan sugar molecules (antibodies to lectin, AbLec) that releases the immune system brakes against many types of tumors @carolynbertozzi.bskyverified.social @jcstark.bsky.social www.nature.com/articles/s41...

It was a great meeting at OHSU, and it’s always fun to connect with @carolynbertozzi.bskyverified.social alum!

Had a blast at the OHSU Chemical Biology & Physiology meeting this week! Amazing talks, great to see lab alum Brittany White-Mathieu’s developing program at UNH, reconnect with friends and collaborators, meet some of the next generation of #chembio, and explore Portland!

Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏 www.biorxiv.org/content/10.6...

Do you know outstanding undergraduate researchers who could use up to $1,000 in travel funding to present their work at the Spring @acs.org or @pittcon.bsky.social Meetings? Please encourage them to apply for a Kolthoff award! Deadline is Jan. 12, 2026. acsanalytical.org/undergraduat...

And of course thanks to all co-authors and hopefully reaching out to future users @gundrylab.bsky.social @nmriley.bsky.social @khookh.bsky.social @cashwood.proteaglyco.com @wandalllab.bsky.social @glyconet.bsky.social and so many I cannot include...

Do you know outstanding undergraduate researchers who could use up to $1,000 in travel funding to present their work at the Spring @acs.org or @pittcon.bsky.social Meetings? Please encourage them to apply for a Kolthoff award! Deadline is Jan. 12, 2026. acsanalytical.org/undergraduat...

Know an inspiring early-career chemist? Nominate an early-career chemist for the 2026 Talented 12 at cen.acs.org/sections/tal... Submit your nomination by January 20, 2026. #CENT12 #MassSpec #Chemistry

This subject came up in the Nobel Minds broadcast (2022) during the conversation at 25:50, note economics Laureate Ben Bernanke’s “puzzlement” as to Why, and the audience’s response to the entire exchange. youtu.be/LutI8YqJkqM?...

For solving a 50-year mystery by uncovering the machinery behind BMP, a molecule with protective effects against various disorders, Uche Medoh is the winner of the 2025 Science & SciLifeLab Prize for Young Scientists. 🎉 Learn more about the work: https://scim.ag/4qVpK1a

Excited to share our laboratory's research tools to study Siglecs along with some interesting discoveries with these tools. Lot of help from many group, but @zeinab-jc.bsky.social was the major driver of this work. Please reach out if you would like to try them out. www.science.org/doi/10.1126/...

Congratulations to Bill Noble on receiving the 2026 Gil Omenn Computational Proteomics Award from US HUPO! us-hupo.org/Computationa...

Congratulations to Mike MacCoss on receiving the Donald F. Hunt Distinguished Contribution in Proteomics Award from US HUPO! us-hupo.org/Distinguishe...

Have fun with the poster presentation today @timveth.bsky.social!

The overlap of #HUPO2025 with #SFG2025 this week means I’m missing out on the #glycotime fun at SFG in San Diego. I am happy postdoc @timveth.bsky.social is able to represent @riley-research.bsky.social at SFG instead!

@timveth.bsky.social is not only attending #SFG2025 - he helped organize Glycopalooza events for early career researchers and is presenting poster B10-110 Tuesday. Check it out in session 2 to hear his impressive work integrating bottom-up and top-down methods to define glycoproteoform heterogeneity

Not only did Kayla do a great job with her #HUPO2025 presentation, but she also was recognized this afternoon as one of the winners of the competitive 2025 Quantitative Proteomics Grant from Thermo Fisher Scientific. Way to go, Kayla!

The overlap of #HUPO2025 with #SFG2025 this week means I’m missing out on the #glycotime fun at SFG in San Diego. I am happy postdoc @timveth.bsky.social is able to represent @riley-research.bsky.social at SFG instead!

If you are at #HUPO2025 and want to see some recent work from @riley-research.bsky.social, come check out Kayla’s talk on Monday afternoon in the Glycoproteomics session in the Frontenac Ballroom! My poster on our recent work informatics tools is on Monday afternoon too. See you there! #glycotime

If you are at #HUPO2025 and want to see some recent work from @riley-research.bsky.social, come check out Kayla’s talk on Monday afternoon in the Glycoproteomics session in the Frontenac Ballroom! My poster on our recent work informatics tools is on Monday afternoon too. See you there! #glycotime

Understanding m/z range settings for MS/MS scans: a case study with intact glycopeptides chemrxiv.org/engage/... --- #proteomics #prot-preprint

Our manuscript describing @riley-research.bsky.social's GlyCounter informatics tool is now in press at Molecular and Cellular Proteomics. Congrats to first-author Katie Kothlow, her first first-author paper! The manuscript is available here: www.mcponline.org/article/S153...

Awesome to see GlyCounter at work! www.biorxiv.org/content/10.1...

🧪#glycotime

Our manuscript describing @riley-research.bsky.social's GlyCounter informatics tool is now in press at Molecular and Cellular Proteomics. Congrats to first-author Katie Kothlow, her first first-author paper! The manuscript is available here: www.mcponline.org/article/S153...

If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back. I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support

Have you wondered how nanoparticle protein coronas (e.g., Seer’s Proteograph XT) can help with glycoprotein enrichment in biofluids? We were curious, too, and this new @riley-research.bsky.social pre-print led by outstanding postdoc @emmajays.bsky.social details our #glycotime investigations.

Can nanoparticles help us probe the glycoproteome? The new pre-print from @riley-research.bsky.social seeks to answer this question using the Proteograph technology from Seer Inc. Check out this lovely study on glycoproteins NP-enriched from biofluids here: chemrxiv.org/engage/chemr...

Have you wondered how nanoparticle protein coronas (e.g., Seer’s Proteograph XT) can help with glycoprotein enrichment in biofluids? We were curious, too, and this new @riley-research.bsky.social pre-print led by outstanding postdoc @emmajays.bsky.social details our #glycotime investigations.

Dr. Tim Veth, a postdoc working with @nmriley.bsky.social at the University of Washington, is tackling glycoproteomics. When we spoke about navigating the complexity of analysing thousands of glycoproteoforms, he shared how reliable chromatography supports his research. Learn more: bit.ly/4nrMzad

@nmriley.bsky.social, a chemical biologist at University of Washington and one of C&EN's Talented 12, will be speaking at the #CENT12 Symposium on Monday, August 18 in Washington, DC. RSVP here: connect.discoveracs.org/talented-12-... Read more: cen.acs.org/biological-c...

"I invite all researchers to enter the glycoproteomics field and join the battle.” With the complexity of glycoproteomics and how little we still know, Tim Veth puts out a rallying cry to speed up development in this promising field. Learn more about Tim & read our discussion: bit.ly/3IXpo8B

@riley-research.bsky.social had a great time catching up with local research at the Cascadia Proteomics Symposium last week. The lineup featured talks from Katie Kothlow and Haley Schramm, and a lightning talk/poster from @emmajays.bsky.social Congrats to Emmajay for her 2nd-place poster award too!

Can you believe there's more?! Check out a Spotlight from @timveth.bsky.social and @nmriley.bsky.social highlighting an article on glycoproteomics, and another from Lucia Alvarez and Lucia @chemeslab.bsky.social on intrinsically disordered proteins!

The 500 additional GRFPs NSF awarded were not very evenly distributed across fields, it seems. www.science.org/content/arti...

We plan to highlight a new analytical chemist each quarter in the Division Newsletter. If you are interested in nominating someone to be highlighted, please enter their information here: docs.google.com/forms/d/e/1F...

The ACS Div. of Analytical Chem. Education Committee launched a "Meet an Analytical Chemist" initiative this spring to highlight members of our community. Our newest entry showcases @shirajoudan.bsky.social, an Asst. Prof. of Chemistry at @ualberta.bsky.social. Check it out here: shorturl.at/7VFIR

RIP Alan Marshall, one of the greatest mass spectrometrists ever, and a great human to boot. nationalmaglab.org/careers/meet...

Nick Riley @nmriley.bsky.social at #ASMS2025 Varying ETD and EThcD parameters (q and Tau values) for increase O-glycopeptide identifications.

#ASMS2025 offers great evening workshops. If you are interested in real-time decision-making during MS data acquisition or still looking for one to join, consider the Real time Mass Spectrometry Workshop featuring speakers and panelists Sarah Sipe, Aarthie Senathirajah, and Manuel Peris Diaz.

#ASMS2025 Come here about the latest in real-time instrument control including applications to single cell proteomics (@parallelsq.bsky.social), #glycotime, and quantitative proteomics!

#ASMS2025 offers great evening workshops. If you are interested in real-time decision-making during MS data acquisition or still looking for one to join, consider the Real time Mass Spectrometry Workshop featuring speakers and panelists Sarah Sipe, Aarthie Senathirajah, and Manuel Peris Diaz.

@riley-research.bsky.social is excited for #ASMS2025 in Baltimore! We made sure to capitalize on some of the classics, like a crab dinner at LP Steamers and an Orioles game, before the conference festivities kicked off. Come hear what we have been up to!

Great to see #proudofalumni @nmriley.bsky.social on the @cenmag.bsky.social Talented 12 list! 🎉 🏆 Check out his #glycotime research program: www.riley-research.com

Nick Riley @nmriley.bsky.social gets recognition as one of the ACS C&EN 2025 Talented 12! cen.acs.org/biological-c...

@nmriley.bsky.social of @riley-research.bsky.social is pursuing better ways to study the biochemistry of sugars that decorate cell surfaces. He hopes that someday scientists could analyze these sugars en masse to infer the health of the cell. Read more: cen.acs.org/biological-c... #CENT12 #chemsky🧪

Interested in prediction tasks involving peptide mass spectra? Our foundation model uses pre-trained spectrum representations learned by a de novo sequencing model to solve many tasks better and with less data, from recognizing chimeras to separating N- and O-glycopeptides. arxiv.org/abs/2505.10848