UW Genome Sciences
@uwgenome.bsky.social
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The Department of Genome Sciences at The University of Washington
Congratulations to Riku Yasutomi on being awarded an NRSA Fellowship!
5 days ago
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Congratulations to Andrew Stergachis on being elected to the American Society for Clinical Investigation!
5 days ago
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Congratulations to the Stergachis Lab on being awarded an AI for Science fund award from Google!
blog.google/company-news...
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We’re announcing the 12 recipients of our AI for Science fund
A look at the 12 recipients of the first AI for Science fund.
https://blog.google/company-news/outreach-and-initiatives/google-org/announcing-ai-for-science-awardees/
22 days ago
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Intracellular interactions shape antiviral resistance outcomes in poliovirus via eco-evolutionary feedback
www.nature.com/articles/s41...
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Intracellular interactions shape antiviral resistance outcomes in poliovirus via eco-evolutionary feedback - Nature Ecology & Evolution
A model of intrahost poliovirus replication shows that, after several rounds of replication, pocapavir, a poliovirus capsid inhibitor, collapses viral density, preventing intracellular interactions th...
https://www.nature.com/articles/s41559-025-02926-x
2 months ago
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Mapping single-cell diploid chromatin fiber architectures using DAF-seq
www.nature.com/articles/s41...
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Mapping single-cell diploid chromatin fiber architectures using DAF-seq - Nature Biotechnology
Single-molecule chromatin fiber sequencing exposes single-cell-level heterogeneity in the chromatin architecture of individual regulatory elements.
https://www.nature.com/articles/s41587-025-02914-3
3 months ago
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Congratulations to David Baker, Riza Daza, Evan Eichler, Mike MacCoss, Brendan MacLean, Hannah Pliner, Jay Shendure, and Cole Trapnell on being named to the Clarivate Highly Cited Researchers List for 2025!
3 months ago
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Congratulations to Joe Felsenstein on being awarded the 2026 Mendel Medal by the Genetics Society!
genetics.org.uk/medals-and-p...
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Mendel Medal 2026 - Professor Joe Felsenstein | Genetics Society
The Mendel Medal 2026 has been awarded to Professor Joe Felsenstein. Professor Joe Felsenstein was born in 1942, grew up in Philadelphia and studied as an
https://genetics.org.uk/medals-and-prizes/genetics-society-medals-and-lectures/mendel-medal/mendel-medal-2026-professor-joe-felsenstein/
3 months ago
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Congratulations to Alison Feder on being named a 2025 Freeman Hrabowski Scholar!
www.hhmi.org/programs/fre...
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The 2025 Freeman Hrabowski Scholars | HHMI
Freeman Hrabowski Scholars are outstanding early career faculty who have the potential to become leaders in their research fields.
https://www.hhmi.org/programs/freeman-hrabowski-scholars/2025-scholars
3 months ago
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Congratulations to Bill Noble on receiving the 2026 Gil Omenn Computational Proteomics Award from US HUPO!
us-hupo.org/Computationa...
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US HUPO - Computational Proteomics Award
https://us-hupo.org/Computational-Proteomics-Award
3 months ago
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Congratulations to Mike MacCoss on receiving the Donald F. Hunt Distinguished Contribution in Proteomics Award from US HUPO!
us-hupo.org/Distinguishe...
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US HUPO - Distinguished Contribution Award
https://us-hupo.org/Distinguished-Contribution-Award
3 months ago
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Congratulations to Winston Dredge on being awarded a WRF Postdoctoral Fellowship!
4 months ago
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Jay Shendure elected to National Academy of Medicine
newsroom.uw.edu/blog/jay-she...
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Jay Shendure elected to National Academy of Medicine - UW Medicine | Newsroom
https://newsroom.uw.edu/blog/jay-shendure-elected-to-national-academy-of-medicine
4 months ago
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CellCover Defines Marker Gene Panels Capturing Developmental Progression in Neocortical Neural Stem Cell Identity
elifesciences.org/reviewed-pre...
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https://elifesciences.org/reviewed-preprints/107531
4 months ago
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Mechanisms underlying thermally induced growth plasticity in juvenile Pacific halibut
journals.biologists.com/jeb/article/...
4 months ago
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Epithelial competition determines gene therapy potential to suppress Fanconi Anemia oral cancer risk
journals.plos.org/ploscompbiol...
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Epithelial competition determines gene therapy potential to suppress Fanconi Anemia oral cancer risk
Author summary We investigated factors influencing the success of oral mucosal gene therapy for Fanconi Anemia (FA), a genetic syndrome marked by DNA repair defects in conjunction with a heightened ri...
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012915
5 months ago
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Registration is now open for the Mutational Scanning Symposium!! 25-27 March 2026 Melbourne, Australia Matt Hurles (Wellcome Sanger) and Maitreya Dunham (University of Washington) Deadline for abstract submissions: 2 November 2025.
www.mss2026.org
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MSS26
Mutational Scanning Symposium 2026, 25-27 March, Melbourne
https://www.mss2026.org
5 months ago
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reposted by
UW Genome Sciences
EichlerLab
5 months ago
🧬 How fast do humans mutate? Our groundbreaking study tracks DNA changes across 4 generations to reveal the pace of human evolution revealing insights into our genetic legacy. Watch now 👉
youtu.be/6TTCZdZd4Y4
#Genetics
#Evolution
#ScienceVideo
#Nature
@hhmi.org
@uwgenome.bsky.social
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How quickly do humans mutate? Four generations help answer the question
YouTube video by nature video
https://youtu.be/6TTCZdZd4Y4
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Congratulations to Zukai Liu and Bria Metzger on being awarded Parker Travel Awards for best poster at the 2025 department retreat!
5 months ago
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Multiplex and multimodal mapping of variant effects in secreted proteins via MultiSTEP
www.nature.com/articles/s41...
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Multiplex and multimodal mapping of variant effects in secreted proteins via MultiSTEP - Nature Structural & Molecular Biology
Multiplexed assays of variant effect can resolve clinical variants but are incompatible with secreted proteins. Here Popp et al. develop MultiSTEP, a generalizable surface-tethering method to assess v...
https://www.nature.com/articles/s41594-025-01582-w
5 months ago
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Congratulations to Olivia Waltner on being awarded the Bonita and David Brewer Fellowship!
6 months ago
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Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae
www.science.org/doi/10.1126/...
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Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae
The constraints that govern the evolution of gene expression patterns across development remain unclear. Single-cell RNA sequencing can detail these constraints by systematically profiling homologous ...
https://www.science.org/doi/10.1126/science.adu8249
6 months ago
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Accelerating Biomolecular Modeling with AtomWorks and RF3
www.biorxiv.org/content/10.1...
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Accelerating Biomolecular Modeling with AtomWorks and RF3
Deep learning methods trained on protein structure databases have revolutionized biomolecular structure prediction, but developing and training new models remains a considerable challenge. To facilita...
https://www.biorxiv.org/content/10.1101/2025.08.14.670328v2.abstract
6 months ago
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Congratulations to Jenny Nathans on being awarded an NRSA Fellowship!
7 months ago
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Congratulations to Caleb Carr on being awarded an NRSA Fellowship!
7 months ago
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Complex genetic variation in nearly complete human genomes
pubmed.ncbi.nlm.nih.gov/40702183/
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Complex genetic variation in nearly complete human genomes - PubMed
Diverse sets of complete human genomes are required to construct a pangenome reference and to understand the extent of complex structural variation. Here we sequence 65 diverse human genomes and build...
https://pubmed.ncbi.nlm.nih.gov/40702183/
7 months ago
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reposted by
UW Genome Sciences
EichlerLab
7 months ago
Using >130 human & 12 primate haplotypes, we reconstruct the chromosome 22q11.2 evolution to identify haplotype structures linked to deletions or inversions, explaining the lower prevalence of 22q11.2 deletion syndrome in individuals of African descent.
@hhmi.org
@uwgenome.bsky.social
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Congratulations to Maggie Russell on receiving the UW Graduate School's Distinguished Dissertation Award!
8 months ago
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Congratulations to Leah Anderson on winning the best talk award at the Pacific Northwest Yeast Club meeting!
www.pnwyc.net
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PNWYC
PNWYC 2025 Meeting A day for yeast labs in the Pacific Northwest to get together and share research, outreach, teaching, and more! June 20th, 2025, in Vancouver, Canada Michael Smith Laboratories, Uni...
https://www.pnwyc.net/
8 months ago
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Congratulations to Alison Feder on receiving the SMBE 2025 Early-Career Excellence Award!
members.smbe.org/news/Details...
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SMBE 2025 Faculty Award Winners
SMBE is delighted to announce our 2025 Faculty Award Winners! Early-Career Excellence Award winner: Alison Feder Alison Feder is an Assistant Professor of Genome Sciences at the University of Washingt...
https://members.smbe.org/news/Details/smbe-2025-faculty-award-winners-273805
8 months ago
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Congratulations to Leah Anderson and Elliott Swanson on receiving the Sonia Ting Travel Award!
8 months ago
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Gene clusters linked to insulin resistance identified in a genome-wide study of the Taiwan Biobank population
www.nature.com/articles/s41...
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Gene clusters linked to insulin resistance identified in a genome-wide study of the Taiwan Biobank population - Nature Communications
Understanding genetic drivers of insulin resistance is crucial for addressing metabolic disorders. Here, the authors show associations involving GCKR, MLXIPL, APOA5, and APOC1, highlighting adipose ti...
https://www.nature.com/articles/s41467-025-58506-x
9 months ago
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Harmful algal blooms are preceded by a predictable and quantifiable shift in the oceanic microbiome
www.nature.com/articles/s41...
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Harmful algal blooms are preceded by a predictable and quantifiable shift in the oceanic microbiome - Nature Communications
Harmful algal blooms (HABs) pose negative worldwide impacts that could be minimized through the development of a forecasting tool. Quantitative analysis of peptides produced by a coastal microbiome pr...
https://www.nature.com/articles/s41467-025-59250-y
9 months ago
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Population size interacts with reproductive longevity to shape the germline mutation rate
www.pnas.org/doi/10.1073/...
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PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
https://www.pnas.org/doi/10.1073/pnas.2423311122
9 months ago
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Congratulations to Lara Muffley on being awarded the UW Distinguished Staff Award for Collaboration!
www.washington.edu/facultystaff...
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UW Announces 2025 Awards of Excellence Recipients
The UW is delighted to announce the recipients of the 55th annual University of Washington Awards of Excellence! The awards honor outstanding alumni, faculty, staff, students and retirees who...
https://www.washington.edu/facultystaff/2025/05/01/uw-announces-2025-awards-of-excellence-recipients/
9 months ago
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GS grad Lizzie Plender is featured on the ASHG Trainee Excellence Spotlight Podcast!
podcasts.apple.com/us/podcast/t...
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Trainee Excellence Spotlight: Elizabeth Plender, BS/BA
Podcast Episode · Trainee Excellence Podcast · 12/19/2024 · 27m
https://podcasts.apple.com/us/podcast/trainee-excellence-spotlight-elizabeth-plender-bs-ba/id1606246832?i=1000681006519
10 months ago
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reposted by
UW Genome Sciences
UW Medicine Newsroom
10 months ago
2025 Public Welfare Medalist
@nasonline.org
Mary-Claire King,
@uwdeptmedicine.bsky.social
@uwgenome.bsky.social
@uwmedicine.bsky.social
cancer geneticist, gave her acceptance speech April 27 at an awards ceremony held during the 162nd annual meeting of the National Academy of Sciences
#NASAward
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Congratulations to Hannah Jordt (faculty), Deanna Plubell (postdoc), Sandra Pennington (staff), and Leah Anderson (student) on receiving the UW Genome Sciences Department Outstanding Service Award!
10 months ago
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4 generations help science explore genome mutation rate
newsroom.uw.edu/news-release...
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4 generations help science explore genome mutation rate - UW Medicine | Newsroom
https://newsroom.uw.edu/news-releases/4-generations-help-science-explore-genome-mutation-rate
10 months ago
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Peptide biomarkers predict coral survival from heat stress
newsroom.uw.edu/news-release...
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Peptide biomarkers predict coral survival from heat stress - UW Medicine | Newsroom
https://newsroom.uw.edu/news-releases/peptide-biomarkers-predict-coral-survival-from-heat-stress
10 months ago
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A transformer model for de novo sequencing of data-independent acquisition mass spectrometry data
www.biorxiv.org/content/10.1...
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A transformer model for de novo sequencing of data-independent acquisition mass spectrometry data
A core computational challenge in the analysis of mass spectrometry data is the de novo sequencing problem, in which the generating amino acid sequence is inferred directly from an observed fragmentat...
https://www.biorxiv.org/content/10.1101/2024.06.03.597251v1
10 months ago
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Complete sequencing of ape genomes
www.nature.com/articles/s41...
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Complete sequencing of ape genomes - Nature
Complete sequences of chromosomes telomere-to-telomere from chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang provide a comprehensive and valuable resource for future evol...
https://www.nature.com/articles/s41586-025-08816-3
10 months ago
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Congratulations to Chris McGann and Bo Wen on receiving graduate student awards at the 2025 ASMS Conference!
10 months ago
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Congratulations to Abby McGee and Val Browning on being awarded NSF Fellowships, and to Matt Chaw, Marazzano Colon, Bria Metzger, Rachel Powell, and Catherine Sniezek on receiving honorable mention!
11 months ago
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Predicting cell cycle stage from 3D single-cell nuclear-stained images
www.life-science-alliance.org/content/8/6/...
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Predicting cell cycle stage from 3D single-cell nuclear-stained images
The cell cycle governs the proliferation of all eukaryotic cells. Profiling cell cycle dynamics is therefore central to basic and biomedical research. However, current approaches to cell cycle profili...
https://www.life-science-alliance.org/content/8/6/e202403067
11 months ago
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Congratulations to Syd Sattler on receiving the first place travel award for best graduate student talk at the Northwest Development Biology conference!
11 months ago
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Celeste Berg has been named an AAAS Fellow.
www.washington.edu/news/2025/03...
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Five UW researchers named AAAS Fellows
Five University of Washington researchers have been named AAAS Fellows, according to a March 27 announcement by the American Association for the Advancement of Science. They are among 471 newly...
https://www.washington.edu/news/2025/03/27/five-uw-researchers-named-aaas-fellows/
11 months ago
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Congratulations to Connor Finkbeiner on being awarded an NRSA Fellowship!
11 months ago
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Congratulations to Xavi Guitart / General Molecular Electronics on winning second place at the UW Hollomon Health Innovation Challenge!
www.geekwire.com/2025/tech-to...
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Newborn jaundice detection tool wins grand prize at University of Wash. health innovation challenge
University of Washington students won the grand prize at the UW's Hollomon Health Innovation Challenge for their jaundice-detecting technology.
https://www.geekwire.com/2025/tech-to-aid-jaundiced-babies-wins-health-innovation-prize-at-university-of-washington-competition/
11 months ago
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Alison Feder has received the Early Career Achievement in STEM award from Seattle AWIS.
seattleawis.org/awards/
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Awards & Banquet – Seattle AWISLinkedIn iconTwitter icon
https://seattleawis.org/awards/
12 months ago
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Mary-Claire King to receive NAS Public Welfare Medal
newsroom.uw.edu/news-release...
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Mary-Claire King to receive Public Welfare Medal - UW Medicine | Newsroom
https://newsroom.uw.edu/news-releases/mary-claire-king-to-receive-public-welfare-medal
12 months ago
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