Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps. @pnas.org @ub.edu www.pnas.org/doi/10.1073/... #ActiveMatter #Microfluidics #SoftMatter

Maria Tettamanti shows that inhibition of TORC2 by the small amphipath PalmC induces the TORC2-dependent internalization of sterols. Congrats to Maria and all coworkers involved, and to EMBOj for the efficient review process: use review commons! @biology-unige.bsky.social @sciencesunige.bsky.social

Etienne @membramics-lab.bsky.social is very happy to visit @rouxlab.bsky.social in Geneva! great people, great projects, good memories...

‪ Congratulations @centriolelab.bsky.social @dudinlab.bsky.social and @gautamdey.bsky.social for your publication in @cp-cell.bsky.social: Charting the landscape of #cytoskeletal diversity in #microbial eukaryotes #Expansion #Microscopy @sciencesunige.bsky.social www.unige.ch/medias/en/20...

*ALL*source data and Python notebooks are available (you can reproduce all figures!) 🔗 doi.org/10.6084/m9.f... We hope this helps make lifetime analysis transparent and comparable across setups. 📄 www.biorxiv.org/content/10.1... @rouxlab.bsky.social #FLIM #FlipperTR #Microscopy #OpenScience

🚨 New preprint out! “Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM” with Tithi Mandal and @rouxlab.bsky.social We benchmark and describe step-by-step Flipper-TR FLIM measurements across different set-ups and and strategies. www.biorxiv.org/content/10.1...

I am pleased to 📣 today’s superb thesis defense by Christian Schroer on “Chemical strategies for studying lipid signaling and transport”. Part of his work was recently published in the JLR; the other part will follow soon. A very proud and somewhat tipsy “Doktorvater” 🥂

Undergraduate/internship/master's thesis position: jobs.helsinki.fi/job-invite/4...

PhD student position: jobs.helsinki.fi/job-invite/4...

I have a PhD student and an undergrad student positions open at the Institute of Biotechnology @helsinki.fi We are using reconstitution, cell and structural biology to study protein-membrane interactions and membrane microdomain formation. Links to calls below! Feel free to drop a message and share!

"Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C" out now in PLOS Biology journals.plos.org/plosbiology/...

Order matters! Aurelien Roux @rouxlab.bsky.social studied the formation of multi-cellular tornado-like structures and regeneration of heads in hydra to share with us how stress fields, topology and geometry of initial tissue organization set the sequence of morphogenesis. #MBIMPG2025

Previous preprint is now published in RSC Chemical Biology. If you are interested in plasma membrane labeling, see the paper! 👇 pubs.rsc.org/en/content/a...

Nice discussions after the talk given online yesterday at cytophys.org, presenting the work of @pauguillamat.bsky.social @clairedessalles.bsky.social @yamini-ravichan.bsky.social @oriolmb.bsky.social and Tithi Mandal. Available on the lab youtube channel at: youtu.be/g-7HomnPdtk

Ever wished to become an actin star? 😎 Then try getting suspended above a non-adhesive substrate. www.nature.com/articles/s41...

Hello microscopy and imaging experts and enthusiasts! We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English). Please apply and/or repost! jobs.unige.ch/www/wd_porta...

The @embo.org ESCRT meeting was packed with membrane remodeling from every branch of the tree of life🌳. Some awesome science 🧪 highlights in the next posts 🧵. But a first impression… the venue!! Wow, Caux castle up a cogwheel train, overlooking Lac Léman! Perfect! 🌄 Thank you @rouxlab.bsky.social 🤗

What a fantastic ESCRT meeting, the field is going strong and full of exciting science. Many thanks to @rouxlab.bsky.social @cellarchlab.com @jujumathieu.bsky.social @magromayor.bsky.social @majarad.bsky.social for organising such a a great event

🤩 Last week I successfully defended my PhD! It was such a special day, made even better by having friends, family, and colleagues there with me. Thanks for all the support and kind words! Huge thanks to my jury members for the thoughtful feedback and conversations. @soldatilab.bsky.social

Thank you for this opportunity @the-node.bsky.social to let me share the behind the story of my postdoc article from the @rouxlab.bsky.social here’s to squishing jellies!!

This was a truly exciting talk from Aurelien Roux @rouxlab.bsky.social from Univ. Geneva 👏👏. From his landmark work on membranes to tissues now, the continuing theme is the role of geometry, topology and curvature in morphogenesis. Thanks for visiting us 🤩

The amazing tour de force of the great @lcferme.bsky.social is now out in its final form in @ScienceAdvances (not on Bluesky???). It was hard work and all the conceptual advance was her doing. Check it out: www.science.org/doi/epdf/10....

Just one week to go ⏳ until the "Cellular Interfaces Across Scales: From Molecules to Tissue Dynamics" meeting @sfb1348.bsky.social @uni-muenster.de We can't wait to see you there! crc1348-conference.ycode.site #DynamicCellularInterfaces #Münster

The lab is on a roll. 2nd preprint in as many weeks! High levels of Cdc42 GTPase underlie an all-or-none decision to fuse. Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social www.biorxiv.org/content/10.1... @biology-unige.bsky.social

New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction. A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social! www.biorxiv.org/content/10.1...

#newPI and time is running. It has already been a month since I officially joined the University of Warwick as Assistant Professor. I am excited to announce and build the Fluorescence and Membrane Dynamics (FMD) Lab: warwick.ac.uk/fac/sci/med/...

"The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage" out now in Nature Cell Biology rdcu.be/ehbaL

Abstract submissions for short talks are still opened until April 20th for the EMBO Escrt meeting 2025. There are plenty of options for short talks, please apply online at meetings.embo.org/event/25-escrt

Thats the proof, that PI to PI knowledge transfer can still work (for now😂). Yay very happy.

Interested in how cells respond when squeezed? Check the review paper just published by Laura Faure, @valeriaventurini.bsky.social and myself on this. Really thorough and clear revision by Laura and Valeria!

Grateful for the opportunity to present my work last week at #EMBOcellBio24. A big thank you to @humantechnopole.bsky.social and @embo.org for organizing such an inspiring event with an impressive lineup of speakers in the stunning Austrian landscape!

A short reminder that registrations for the EMBO ESCRT meeting 2025 in Montreux June 23rd-June27th are still opened! Please register online at meetings.embo.org/event/25-escrt

Paper 4: @rouxlab.bsky.social lab studied contractility-curvature dynamics in/on cell tubes ➡️ impacting tissue remodeling with proliferation and extrusion.

Cloud attack on Matterhorn today

Uh oh...... Pubmed appears to be down....

In this interview, Dominique Bergmann @stanfordstomata.bsky.social talks about her research in stomatal development, her role as an Editor at Development, and how her passion for comparative biology has influenced her career: https://doi.org/10.1242/dev.204667

Become our colleagues in Umeå, Sweden :)

Guillamat, P., Blanch-Mercader, C., Pernollet, G., Kruse, K., & Roux, A. (2022). Integer topological defects organize stresses driving tissue morphogenesis. Nature Materials, 21(5) #EpithelialMechanics https://buff.ly/41cHclL

Check out our latest paper in Advanced Science 🥳, where we use viscoelastic hydrogels to better understand how spatial confinement and matrix viscoelasticity jointly regulate cell migration: lnkd.in/diRstW2B Great collaboration between UMONS and @giusciccone.bsky.social @manuelsalmeron.bsky.social

Extremely happy to see our work finally out!🎉 Great collaboration between @rouxlab.bsky.social @buzzbaum.bsky.social labs and a real pleasure to work and share co-first authorship with incredible scientists and friends @diorgeps.bsky.social @sami-c.bsky.social. Big thanks to the rest of the authors!

Check out this thread on MIRO—our new model for testing cancer immunotherapies! #CancerResearch #Immunotherapy

Author tags: @diorgeps.bsky.social, @sami-c.bsky.social, @javierespadas.bsky.social, @buzzbaum.bsky.social, @rouxlab.bsky.social, @sporemohan.bsky.social, @emoody.bsky.social, @tweethinking.bsky.social. @cellbiol-mrclmb.bsky.social (2/2)

New research on ancient Asgard archaeal ESCRT-III proteins reveals evolutionary secrets of membrane remodelling. Diorge Souza, Javier Espadas and Sami Chaaban, investigated the ESCRT-III proteins with Buzz Baum and Aurelien Roux. Read more: www2.mrc-lmb.cam.ac.uk/asgard-archa... #LMBResearch (1/2)

Congratulations to Denni from our @yap-lab.bsky.social team and all authors on the new paper! 🥳 'Advecting scaffolds: Controlling the remodeling of actomyosin with anillin' 👇 journals.aps.org/pre/abstract...

The evolution of shape diversity through the lens of physics—explored in our new paper! A fruitful collaboration between our lab @EMBL, Salbreux’s lab @unige & others, led by @BailleulRichar1—now independent at @ENS_ULM—& Nicolas Cuny. bit.ly/3WRqdEa

ESCRT-III is an ancient complex, present in Archaea, with only two proteins and all membrane remodelling functions. Great work by @javierespadas.bsky.social, @diorgeps.bsky.social, @sami-c.bsky.social, thanks to the @buzzbaum.bsky.social lab! Drawing by Julie Polge. www.science.org/doi/10.1126/...

Adding a shout out to @tweethinking.bsky.social and @emoody.bsky.social! Thanks again to the amazing phylogenetics team! And our unique @mrclmb.bsky.social @cellbiol-mrclmb.bsky.social

The highlight of this project was the collaboration between @buzzbaum.bsky.social and @rouxlab.bsky.social labs, especially working with my incredible friends @javierespadas.bsky.social and @sami-c.bsky.social ! You both rock! 🤜🤛🍻💪

Happy to share our paper’s final version on the evolution, structure, and membrane binding / remodeling of Asgard ESCRT-III proteins! And my first 🦋 post! www.science.org/doi/10.1126/...

The EMBO ESCRT meeting 2025 #EMBOescrt is open for registration: meetings.embo.org/event/25-escrt Please share the info around you, and see you in Montreux!