An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

Such a worthy recipient. Maya is not only a great scientist but also a fantastic mentor and a rich source of inspiration.

📯 shoutout for this beautiful work by Kenji Maeda’s lab, who mapped 300 lipid species across 6 compartiments of humane cells. Besides uncovering general principles of lipid organization, the paper establishes a framework for exploring how lipid landscapes are regulated in physiology and disease 👇🏼

Proud to share a preprint of our paper on how bridge-like lipid transport protein VPS13C senses lysosomal membrane tension in anticipation of membrane lesions to initiate net ER-to-lysosome lipid transfer for efficient lysosomal repair www.biorxiv.org/content/10.1...

🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...

🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...

I am proud to 📣 today’s superb thesis defense by Milena Wessing on “Molecular dissection of ceramide-induced apoptosis: a bottom-up approach”. Two papers describing Milena’s heroic efforts are close to submission. It was a privilege serving as her “Doktorvater” 🥂

I am pleased to 📣 today’s superb thesis defense by Christian Schroer on “Chemical strategies for studying lipid signaling and transport”. Part of his work was recently published in the JLR; the other part will follow soon. A very proud and somewhat tipsy “Doktorvater” 🥂

Great to see this work on imaging cellular lipid logistics in Nature, where it belongs. Chapeau! Many gratulations to Andre, Alf and their co-workers!

🔥🔥🔥 (= highly recommended) 👇🏼

A university & its leadership standing for academic freedom, truth, integrity & shared values deserve support from across the globe. Those believing in these virtues greatly outnumber those who seek to undermine them. As admirer of the 1st class scientists working at UVA, I gladly signed the letter👇

Science is the engine of an open, pluralistic society. So scientists serve a central role in defending it. In 🇩🇪, the association „Wissenschaft für Demokratie – Wir für Dich“ was founded to strengthen the role of science in the public debate & in the fight against disinformation wirfuerdemokratie.org

Thank you so much @jamessaenz.bsky.social‬ for the inspiring #sfb1557 talk on lipid-sensitive riboswitches and the role of lipid diversity & membrane biophysics in the origin of life. A great scientist & wonderful colleague to hang out with 🍺, who is currently on the job market, but not for long… 🚴‍♂️

Academische vrijheid staat onder druk en moet beter worden beschermd. Die conclusie lees je vandaag in dit KNAW-rapport: www.knaw.nl/nieuws/knaw-... Aanbevelingen o.m.: meer vrijheid van onderzoek, bescherming tegen intimidatie en minder inhoudelijke overheidsbemoeienis.

This is an absolute disaster. If we don't stop this, they will turn NSF into a pawn of the Trump administration. There will be no research on climate, biodiversity, or anything that isn't eugenics or AI or how to more efficiently destroy the planet for profit. This cannot be allowed to happen.

Science is under attack. Proposed 40% NIH cut threatens jobs, research, and medical progress. Call your reps, governor, and mayor now—urge them to stand up for science. www.ascb.org/science-poli...

Thank you so much for the warm welcome, @gloriusgroup.bsky.social & @gloriusfrank.bsky.social! I thoroughly enjoyed the wonderful brainstorm on how to capture the complex dance of lipids during cell wounding and repair using the power of synthetic chemistry. So much left to explore and accomplish🧑‍🔬🧪🔬

At membrane contact sites, bridge-like transport proteins, e.g. LPD-3, mediate bulk lipid transfer between cellular organelles. @nature see cryo-EM structure of native LDP-3, and gain insights into its functioning and interaction with other proteins and lipids. shorturl.at/lycuz & shorturl.at/ARpUK

For everyone interested in organoid technology and skin regeneration there is a great postdoc opportunity in the Bartscherer Lab. Check out the posting below. www.uni-osnabrueck.de/universitaet... www.biologie.uni-osnabrueck.de/en/research/...

Groundbreaking study in Cell from @leventallab.bsky.social: phospholipid asymmetry is a defining feature of the plasma membrane and cholesterol fills the holes — major implications for how this membrane works. A #lipidtime must-read! www.cell.com/cell/abstrac...

📯📯📯 10 days left to apply for the International Master MemBioMed "From Membrane Biology to Neuroscience & Experimental Medicine". Scholarships available for selected students to acquire intensive training in analysing the complex behavior of biomembranes and exploiting their therapeutic potential 👇👇

This is a beautiful paper. Very important implications - and further evidence for the link between lipid transbilayer movement / lipid asymmetry and directional lipid transport.

Review @cp-cellchembiol.bsky.social @volkerhaucke-lab.bsky.social Mechanisms and functions of lysosomal lipid homeostasis www.cell.com/cell-chemica...

Taking a cue from @cantlonlab.bsky.social, I have written an op-ed for my local newspaper about the impact of the NIH funding chaos. I'd appreciate it if you read and share. #NIH #Research #Science #Worcester www.telegram.com/story/opinio...

Who would have ever thought of such a thing happening?

Friends! The science that we love is under threat. World-wide, there're forces seeking to make it corporate-like, focused on deliverables, or even the enemy of society. Take a stand & celebrate science & music! #theconferencetoendallconferences - Registration starts NOW! woodstock.img.cas.cz

Pubmed has been down since yesterday. If this is a result of Trump’s NIH funding freeze, it’s extremely bad news for the scientific community not just in the USA but across the world.

2 weeks left to sing up! Membrane dynamics from single cells to whole organisms! Come and hang out with us in sunny San Feliu! Please re-post

🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏

PLOS statement. Any attempt to restrict knowledge creation or censor its dissemination undermine the core principles of scientific inquiry and obstruct progress. And they stand in direct conflict with our core values, our mission and our editorial policies theplosblog.plos.org/2025/02/plos...

Germany be wise tomorrow

Information, facts, and figures should be the basis of our democracy Sign the petition: www.openpetition.de/petition/onl...

Congrats to Kasparas Petkevicius on his paper just out in Science Advances - Andrew James in my lab played a key role - important implications for Battens Disease doi.org/10.1126/scia...

Scientists are now organizing events, called Stand Up for Science, on 7 March in Washington, D.C., and state capitals. So far, they have attracted more than 100 volunteers from some 30 states who are hoping to rally support for research as a public good. scim.ag/4328LAD

Long in the making but our protocol for gene editing is online! FAB CRISPR is super easy and allows the generation of N and C terminal fusions with TurboID, SNAP, Halo and mStayGold. A single cloninf step to generate HDR templates! arxiv.org/abs/2502.12675 1/n

"Democracy needs Science. Science needs Democracy". Germany is facing a landmark federal election. I am proud to be part of a university whose presidential board takes a clear stance that argues from the self-image of science. Please share👇

Very interesting preprint by the Burd group www.biorxiv.org/content/10.1...

"Democracy needs Science. Science needs Democracy". Germany is facing a landmark federal election. I am proud to be part of a university whose presidential board takes a clear stance that argues from the self-image of science. Please share👇

Cool stuff from Andrey Klymchenko's lab. These plasma membrane labels are a pretty smart design. Check it out! pubs.acs.org/doi/10.1021/...

American science is under attack Opinion piece by Dr Harold Varmus, Nobel Prize winner, former director of the #NIH and the #NCI 🧪 “Perhaps what’s most disheartening is what feels like the absence of widespread opposition to this unraveling” www.nytimes.com/2025/02/14/o...

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

MD simulations and experiments in cells reveal core structural determinants that govern binding of Hexokinase I to mitochondrial VDACs, a liaison with far-reaching physiological implications. Another great collaborative effort with @melolab.bsky.social and @cg-martini.bsky.social! rdcu.be/d9lO8

You are not powerless, and he is not unstoppable. Look at, and learn from, the funding freeze and how quickly he was forced to surrender.

More VDAC shenanigans, now in interaction with Hexokinase I, in another great collaborative work with @holthuislab.bsky.social and @cg-martini.bsky.social! www.nature.com/articles/s42...

🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏

Five world scientific organisations invite you to sign the Milan Declaration on the Crucial Role of Science in meeting Global Challenges: Join us today by signing the Milan Declaration online at www.febs.org/milan-declar... and supporting its Mission:

This makes me want to be younger. Or do a second masters degree. Would there be an age limit? I highly recommend all students interested in membranes and lipids to apply!

🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏

🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏