Gute Nachrichten - denn was wäre die Welt ohne das Laborjpurnal?!

Gene therapies are revolutionising medicine, but they come with enormous development costs. Why Do Gene Therapies Cost So Much?🤔 ⬇️Read more in our blog⬇️: https://www.fiosgenomics.com/why-do-gene-therapies-cost-so-much/ #bioinformatics

What happens when AI and biology accelerate each other? EMBL Acting Head of AI Centre, Oliver Stegle, discusses how closer integration of these fields could transform the life sciences. Watch this video to learn more. #EMBL_AI

We cooled down the city of Freiburg a bit (currently 23°C) to heat up for the upcoming TriRhena Gene Regulation Club at the MPI-IE. The ½ day symposium starts today at 2PM in the lecture hall – with scientists from @fmiscience.bsky.social, @igbmc.bsky.social & MPI. Looking forward to a 🆒 meeting.

www.nature.com/articles/s41... Check this from @slavov-n.bsky.social

Weekend reads: A tsunami of misleading medical studies; retraction calls cancer therapy timing into question; a closer look at Max Planck’s retractions

For years, the idea of targeted protein degradation stalled because PROTACs were too large and unstable for clinical use. However, in the beginning of May, @fda.gov approved the use of the first PROTAC for adults with a certain form of metastatic breast cancer go.nature.com/4x3NYt7

Most epigenetic-editing platforms, rather than making changes to the DNA itself, modify the markers attached to DNA go.nature.com/4oMVuF4

How can phages with contractile tails to infect Gram-positive bacteria? @plevkalab.bsky.social suggest a mechanism of infection initiation based on structures of the tail and baseplate of phage 812 before and after the tail contraction link.springer.com/article/10.1...

For the second time this month, a team of researchers has reported harnessing a precise gene-editing technique to alter the DNA of human embryos go.nature.com/4vwIXrO

Bluesky launched in February 2023 as an invite-only platform. As of June 2026, we have 45 million users. For reference, that's almost the population of Argentina. Thank you for being here with us 💙 Here’s to the next 45 million accounts.

Special issue call for papers: Biophysics of Membrane Reactions in the Brain. buff.ly/64OBHOY

Are you a recent Ph.D. graduate? Apply for the Science & SciLifeLab Prize for Young Scientists. The $30,000 grand prize will be awarded for outstanding research in cell and molecular biology, genomics, ecology, or molecular medicine. Apply by 15 July: https://scim.ag/4lUpKMN

#PlantSciJobs #PlantSciJob PhD position: Molecular physiology of photosynthesis - Transcriptional and post-translational regulation of C4-CAM photosynthesis in Portulaca. In @renatacferrari.bsky.social ‘s lab @lmu.de www.deutsche-botanische-gesellschaft.de/en/job-openi...

Imagine testing cancer therapies on patient-derived organoids before treatment begins. At the #mdcBerlin Bioengineering Symposium, researchers will discuss how bioengineering is bringing medicine closer to that future. 🗓️ July 6 | Berlin-Buch More details: 👉 www.mdc-berlin.de/news/press/j...#mdcBerlin👈

Important fact before tonight’s football game 🇩🇪:🇪🇨

Joachim inspired my interest in infrared spectroscopy and proton transfer, ever since our first joined publication www.sciencedirect.com/science/arti...

A new #ScienceImmunology study shows that recruitment of IL17A–producing γδ T cells to the brain shapes social behavior in a genetic mouse model that recapitulates features of autism spectrum disorder. https://scim.ag/4eEFMr8

California just performed brain surgery to inject stem cells directly into a patient's striatum, the first time ever for Huntington's. The 6 hour procedure happened inside an MRI scanner. Could this finally stop a disease that has had zero...

Have you ever seen this iconic image of the Ebola virus, from the first known outbreak in DRC in 1976? An electron microscopic image, it was captured by #CDC 's Fred Murphy, a virological giant and a very kind interviewee. He died yesterday. He will be missed, but his scientific legacy lives on.

The F1 region of ATP synthase interacts with TCA cycle enzymes. www.nature.com/articles/s41...

From discovery to real-world impact: what’s next for Precision Health? @nathealth.nature.com Chief Editor @benjaminjohnson.bsky.social shares his take. Join us at Reframing Precision Medicine, 13–15 Oct, London. Abstracts close 30 June #STEMConference #medsky go.nature.com/4eqL6PP

🚨Speaker Alert!🚨 We’re excited to welcome Gunter Meister to our upcoming #CRC1678 Seminar 🧬From tRNA modifications to microproteins: non-coding and coding regulation of mitochondrial activity 📅 July 1 📍CECAD Lecture Hall ⏰ 2 PM Dive into the RNA‑driven mechanisms that control mitochondrial activity!

Stay safe!

📬 Issue 12 of 2026 is now live! Featuring: 🧠 A review on neurodevelopmental disruption in primary mitochondrial disorders. 🔬 Original research into development, signalling, mitochondria, and more. 📡 #Biochemistry #Neuroscience #Development #Mitochondria 🔍 Read the issue here: tinyurl.com/FEBSL12

A paper in Nature describes plague outbreaks dating back to around 5,500 years ago documented in hunter-gatherer communities from southeast Siberia. The findings, based on an analysis of ancient DNA, may be the oldest-known evidence of the plague and could shed light on its origins. 🧬🏺🧪

Ina @inahuppertz.bsky.social and Kathrin @katleppek.bsky.social cordially invite all RNA enthusiasts based in the Rhineland region to attend our series of inspiring in-person talks on RNA-related topics by local and invited speakers. This time on Monday July 13th in the DZNE auditorium in Bonn.

1/ Mitochondrial Na⁺ links metabolism, Ca2+ signaling and disease. We know how it gets in, how it gets out, and proteins that use it. But: we've never actually seen Na⁺ in single mitochondria in live cells. We started with an unusual observation, went down a rabbit hole & found some cool biology .

(1/n) Very excited to share tri-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack: Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)? A: Transient E-P contact (~25-42 nm lasting ~10-20 sec): www.biorxiv.org/content/10.6...

Nature research paper: Spatial distribution of the proteome in the human body and in cancers go.nature.com/4vSiZPk

„Schleuse“ für sperrige Fracht: Neue Details zum Transport von großen Proteinen durch Membranen Wie große Proteine Membranen in Zellen passieren können, ohne diese zu zerstören, zählt zu den großen offenen Fragen der Zellbiologie. Mit... weiterlesen

🚨 BREAKTHROUGH: Scientists Develop a Breathable Vaccine Mist That Delivers Immunity Directly to the Lungs Right Where Viruses Enter Two Scientists Fiona Smaill and Zhou Xing developed AeroVax an inhaled vaccine mist that reaches the lungs in just 2 minutes. pubmed.ncbi.nlm.nih.gov/40603330/

Promising single-dose malaria treatment advances toward pan-African clinical trial Researchers at the German Center for Infection Research (DZIF) have developed a promising single-dose malaria treatment that could help address growing drug resis... weiterlesen

Science Days 22.-24. Oktober 2026, Europapark, Rust, Germany. #outreach #sciencecommunication #scicomm science-days.de/science-days/

Not sure I want to know….

🚨 BREAKTHROUGH: Scientists have engineered a virus that invades and destroys glioblastoma one of the deadliest brain cancers while turning the immune system into a relentless tumor-killing force. This could be a historic shift in cancer treatment. www.sciencedaily.com/releases/202...

The results of a study in Nature Metabolism establish hyperglycosylation as a pathological driver of Alzheimer’s disease and highlight glycan metabolism as an actionable target in the fight against the disease. #alzsky #Neuroskyence 🧪

Second day of the Junior GBM summersymposium at #Synmikro in Marburg!

Nature research paper: Molecular basis of polyadenylated RNA fate determination in the nucleus go.nature.com/4vr9d7c

A new imaging analysis in #ScienceSignaling identifies how the protein PTPN22 controls how #TCells remodel their cytoskeletons to form synapses with their targets—and suggests that defects in this constraint mechanism may contribute to #autoimmunity. https://scim.ag/4fv07kB

RESEARCH | J Chen, B Huang et al. (Peking Union Medical College) ROS-mediated sulfenylation of p-GSK-3β can terminate glycogenesis, leading to hepatic insulin resistance 🧪

🚨 Our Nature paper on Manikomycin is a Research Highlight in Nature Reviews Drug Discovery. A new antibiotic. A new ribosomal target (E-site). Activity against MDR pathogens. doi.org/10.1038/d415...

Opening notes at the #jGBM summer symposium at #Synmikro in Marburg! It’s awesome to see what the city groups south set up. Great program, fantastic speakers, perfect weather. Enjoy the science and the networking!

Wissenschaft braucht Freiheit. Demokratie braucht Wissenschaft. In meiner Rede bei unserer Festversammlung habe ich darüber gesprochen, warum Wissenschaft eine Säule der wehrhaften Demokratie ist. Meine Rede: www.youtube.com/watch?v=jq1I...

Job post! Junior Group Leader position in Halle!

Congratulations, Verena!

#NMI -Brückenprofessor Peter Loskill hat in SWR3 beschrieben, welche Möglichkeiten die Alternativmethoden zu Tierversuchen bereits eröffnen und wo sie an ihre Grenzen stoßen. Ein differenzierter Beitrag zu der oft aufgeheizten Debatte! #3R #NAMs #Tierversuche #angewandteForschung

A new review is online! Wassim Daher, Laurent Kremer and co-authors @umontpellier.bsky.social @inserm.fr @irim-life.bsky.social tell you all you need to know about organelle interplay in host responses and #mycobacterial #resilience. -> link.springer.com/article/10.1...

What Biochemistry is really about:

Do vaccines save lives? Yep! Does antivaxx BS kill? Yep. 👇 Cervical cancer deaths for vaccinated young women fall to zero in England: study www.ctvnews.ca/health/artic...