Ina @inahuppertz.bsky.social and Kathrin @katleppek.bsky.social cordially invite all RNA enthusiasts based in the Rhineland region to attend our series of inspiring in-person talks on RNA-related topics by local and invited speakers. This time on Monday July 13th in the DZNE auditorium in Bonn.

Excited to share our joint efforts on the ratioCitron biosensor platform! 🔬✨ www.biorxiv.org/content/10.6... Norito Tamura @mpiage.bsky.social from my lab enabled ratiometric citrate measurements in flow cytometry for population-scale, single-cell analysis.

Friday 27th March, we had a great 11th Rhineland RNA Club meeting @mpiage.bsky.social with inspiring PhD, postdoc and invited speakers. It's great to see how the community covers a range of topics of all corners of RNA science. Special thanks to @mschosserer.bsky.social & @trentini-lab.bsky.social

We would like to invite all Rhineland RNA enthusiasts to attend our next series of in-person talks, featuring local and invited speakers. Highlights include the external talks by Didier Stainier, Simon Bekker-Jensen and Ranen Aviner. Please, register: tinyurl.com/RhinelandRNA

#PhDPosition open — #RibosomeBiology & #Translation QC 📍 JGU Mainz, Germany 🗓️ Apply by 10 Mar 2026 (or until filled) 🔗 Full details + project options: 👉 ak-winz.pharmazie.uni-mainz.de/jobs/

I'm thrilled to anounce that our latest study on ALS/FTD neurodegenerative diseases has been published. Very proud to be part of this excting project. Many thanks to Clotilde Lagier Tourenne for an amazing longlasting and fruitfull collaboration, #ALS #FTD #Ribosomes www.science.org/doi/10.1126/...

Amazing to have you here! I am looking forward to work together on #RNA and #ageing @mpiage.bsky.social

Very happy to See This Published!!!! Thanks for the collaboration link.springer.com/article/10.1...

Last Friday, we had an inspiring 10th Rhineland RNA Club meeting with top class speakers. It's great to see how the community is growing and the range of topics we're covering. Special thanks to Didier Stainier @stainierlab.bsky.social Simon Bekker-Jensen @bekkerjensenlab.bsky.social, Ranen Aviner!

It was a double ribosome talk day for us in Bonn with talks today by Ranen Aviner from @czbiohub.bsky.social and Simon @bekkerjensenlab.bsky.social from BRIC Copenhagen. Simon is visiting for the @rhinelandrna.bsky.social tomorrow and Ranen is a visiting scientist in my and Ina‘s lab. #RNAsky

Excited to share my first PhD student’s @biorxivpreprint.bsky.social! Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules! Check it out! www.biorxiv.org/content/10.1...

🚨 Lecture 🚨 Our #CRC1678 / MPI-Age guest Dr. Ranen Aviner will give a lecture on "Decoding Translation Dynamics with Riboseq" 📅 November 12, 2025 🕐 1:00–3:00 PM 📍 Seminar Room 2+3, MPI for Biology of Ageing, Joseph-Stelzmann-Str. 9b, Cologne Hosted by @inahuppertz.bsky.social Don’t miss out!

Don't miss our cool event in Cologne @mpiage.bsky.social on 14 November!

Many conserved exons in the heart and brain utilize weak 5 ′ splice sites, yet they are accurately spliced. But how? We show that splicing fidelity is actively enforced through a QKI-U6 checkpoint at the U1→U6 handover in essential cardiac genes during organogenesis. www.biorxiv.org/content/10.1...

Excited to share my PhD research, now on bioRxiv! We report a proteo-transcriptomic reprogramming and resource reallocation in the aging brain. Co–first author with Verena Kluever. Grateful to @forna.bsky.social‬ for mentorship, and to @tatjanat.bsky.social‬, Carlos López Otín & all collaborators🧠

New work from the lab! C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules - Bilican - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1002/...

Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells https://www.biorxiv.org/content/10.1101/2025.08.20.671247v1

🎉 We’re excited to share our very first preprint!! 🎉 "Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells" 👉 doi.org/10.1101/2025... #FirstPreprint #StemCells #Metabolism #Epigenetics #AcetylCoA #HBP #Pluripotency #NewScience

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...

Our RAPPL purification of ribosomes and associated material is out. I am really proud of this study in collaboration primary with Pavlovic-Djuranovic lab, as well as Jovanovic and Hashem Labs. This method aims to replace 60 years old purification of ribosomes by sucrose cushions rdcu.be/ezlhg

Excited to announce our paper describing how allelic variants in ribosome biogenesis factors cause neurodevelopmental disorders. Congratulations to Chunyang Ni, Yudong Wei and Barbara Vona, our collaborators Jun Wu, Reza Maroofian, and Leqian Yu, and all the other authors from across the globe.

🚨 Happy to share our first pre-print 🎉 on the causes of ribosome-associated degradation of CFTR and other transmembrane proteins. We explore how protein folding, ER insertion, and elongation dynamics influence translation arrests in this new class of RQC targets.👇 www.biorxiv.org/content/10.1...

To all post-docs: The Genome Biology dept ‪@embl.org has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

I am happy to share our last preprint, where we identified FASN as an endogenous dsRNA-associated factor and demonstrated that its depletion triggers endodsRNA accumulation and a stronger antiviral response to exogenous dsRNAs,#RNA, #interferon,#immunometabolism www.biorxiv.org/cgi/content/...

🚨🚨🚨 Please RT! We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets. Deadline: 30/09/25👇

Postdoc positions in structural biology of RNA processing complexes. An ERC-funded position will dissect pre-mRNA processing pathways in the infective organism Trypanosoma brucei. An ANR-funded position will characterise large complexes in RNA modification. Details: tinyurl.com/postdoc-RNA-...

So shiny ✨I am so happy to be part of this amazing initiative!

Freshly launched! 🚀 Check out the new CRC 1678 website 🌐 👉 crc1678.uni-koeln.de

Proud to share our work where we resolved a longstanding question regarding the existence of a human telomerase dimer and provided insights into its function. Led by 3 amazing lab members in collaboration with @yiliangding.bsky.social and @rdaslab.bsky.social. www.science.org/doi/10.1126/...

Currently our Mercator Fellow Alice E. Lee from Harvard Medical School is visiting us. We very much welcome Alice in Cologne and we are looking forward to many stimulating discussions with her! 👉 labs.childrenshospital.org/lee-lab

We are very happy to invite you to our 9th Rhineland RNA Club at @dzne.science Bonn with great local speakers and Lena Steckelberg @lenasteckelberg.bsky.social as our invited speaker. All #RNA enthusiasts are welcome! Organized by @inahuppertz.bsky.social and @katleppek.bsky.social. #RNAsky

🚀 Big news for kidney research! CRC/TRR 422 ‘PodoSigN’ has been funded to explore podocyte signaling networks. Proud to see two of our CRC 1678 Group Leaders @muellerrom.bsky.social and @inahuppertz.bsky.social involved in this groundbreaking work! #KidneyResearch #PodoSigN #DFGFunding

Join the Hallegger Lab in Oxford! A post-doc position available to develop neuronal cell models to characterise how TDP-43 aggregation leads to its dysfunction in MND. Highly collaborative project funded by My Name'5 Doddie Foundation @MNDoddie5 Please repost and share widely!

The awesome Helene Kretzmer and I are looking to recruit a join computational PhD student. Applications will be evaluated on a rolling basis, so don't wait! Any questions get in touch. We are looking forward.

What an honour to be part of this initiative #RNA #RNAsky

Mind blown 🤯 rdcu.be/enTz2

CECAD receives renewed DFG funding! 🎉 We continue to unlock the biology of aging 🧬 and advance healthy aging for all! 👵👴 ➡️ uni.koeln/GAPGK #CECAD #AgingResearch #ExcellenceCluster #DFG #HealthyAging @unicologne.bsky.social

Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social, @marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social 🔗 Preprint here tinyurl.com/3a74uanv

It was such a great day #RNA #RNASky

Excited to share this one! We developed an in vivo model for specific manipulation of transfer RNA acetylation and found it serves as a sentinel modification whose loss causes ribosome stalling and stress signaling. Implications for a genetic disorder and cancer. www.science.org/doi/10.1126/...

The first paper from the Leppek lab is published today at @embojournal.org!! 🎉 We designed and evaluated a versatile toolbox for determining IRES activity in cells and embryonic tissues. www.embopress.org/doi/full/10....

ARGONAUTES 2025 The grassroot meeting of Argonaute afficionados is looking for afficionados! Full coverage of Argonautes from prokaryotes to #RNAi, #piRNA and #microRNA Join us in Prague at @imgprague.bsky.social during 27-30/8, 2025. Registration, program and more info here: argonautes.img.cas.cz

We are very happy to invite you to our 8th edition of the Rhineland RNA Club @mpiage.bsky.social with great local speakers and Julian König @koenig-lab.bsky.social as our invited speaker. All #RNA enthusiasts are welcome. Organized by @katleppek.bsky.social and @inahuppertz.bsky.social. #RNAsky

Excited to share the work of Jonathan Perr where he uncovered a surprisingly common feature of cell surfaces - the presentation and clustering of RNA binding proteins with #glycoRNA. Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...

Join our GBM Redox Meeting 2025 in Saarbrücken! We put together an exciting program covering diverse aspects of Redox Regulation in Life. Check out the Programm and register until Feb 28! redox-gbm-meeting-2025.uni-koeln.de #redox #redoxbiology #gbm @gbmev.bsky.social

Come and joint us at @mrclmb.bsky.social ! We have an opening for a new group leader in the Structural Studies Division. We are very interactive and collaborative with amazing facilities and generous core funding. Get in touch with myself or @sjorsscheres.bsky.social if you have any questions.

Very happy to share that my research group has launched at the German Diabetes Center (DDZ) in Düsseldorf! We're looking for a PhD student to study the effects of inter-tissue communication on energy balance and metabolic health. Interested? Get in touch! ddz.de/en/job/docto...

🦋 A starter pack of peer-reviewed journals in all fields of natural sciences 🔬🧪🧬🧠🧫⚛️ #biology #physics #astronomy #botany #chemistry #chemsky #chemisky #ChemBio #MicroSky #microbiology #MolBiol #genomics #neuroscience #PlantScience #PlantBiology #AcademicSky #Academia #research #science #PhDSky #PhD