My first PhD student‘s, Kavan Gor, paper on 5-color single-molecule imaging of co-transcriptional RNA folding is out in @science.org Advances! He finds how RNA modification enzymes, antisense oligonucleotides and ribosomal proteins re-route nascent RNA folding. See more details in EMBL post below!

Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...

Registration is open for "The complex life of #RNA" 2026 @embl.org in Heidelberg! Excellent invited speakers and 30 short talks and even more flash talks selected from the abstracts!

The story of how multiple RBPs cooperate to repress translation is now out in @cp-cellreports.bsky.social by @marcopayr.bsky.social and in a great collaboration with @hennig-lab.bsky.social! www.cell.com/cell-reports...

Thinking Like a Scientist, Part Two: The Omics Illusion network.febs.org/posts/thinki... #FEBSnet

Excited to share my first PhD student’s @biorxivpreprint.bsky.social! Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules! Check it out! www.biorxiv.org/content/10.1...

Travel’s got me wiped, but catching up with @colindascheele.bsky.social, @pierresantucci.bsky.social & @olivierduss.bsky.social at #FEBS2025 made it totally worth it. Huge thanks to Pelin Telkoparan and Dilek Cevik for the wonderful hospitality—what a time in Istanbul!

Excited to share our new @science.org paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals. www.science.org/doi/10.1126/...

The timeline of co-transcriptional #mRNA processing and #modification may have to be revised: cleavage, termination, and #m6A deposition may occur earlier than most #splicing! Potential textbook changing study in bioRxiv by edueyras.bsky.social & Rippei Hayashi labs! www.biorxiv.org/content/10.1...

Five people have seen a color never before visible to the naked human eye, thanks to a new retinal stimulation technique called Oz. Learn more in #ScienceAdvances: scim.ag/442Hjn6

Check out our preprint at BioRxiv revealing mechanisms of mRNP assembly during translation repression: (www.biorxiv.org/content/10.1...). Great collaboration with Olivier Duss (@olivierduss.bsky.social). Great Work Marco Payr (@marcopayr.bsky.social) and thanks for the video, explaining our paper.

Ever wondered how several individual RBPs cooperate to repress translation? Lead by @marcopayr.bsky.social and in great collaboration with @hennig-lab.bsky.social, we simultaneously tracked the binding of several proteins to single mRNA molecules in real-time! www.biorxiv.org/content/10.1...

Great work led by our PhD student Iuliia Kotova in collaboration with Fan Liu @fan-liu.bsky.social, Boris Bogdanow, Lars Mühlberg, and Olivier Duss @olivierduss.bsky.social and Guelsah Gabriel labs. Structural analysis by our PhD student Konstantin Gilep. www.biorxiv.org/content/10.1...

www.science.org/doi/10.1126/... Tour de force by Barna Lab

The RNA helicase HrpA rescues collided ribosomes in E. coli

In a remarkable new paper, Qureshi and Duss use multi-colour single-molecule fluorescence microscopy to directly and simultaneously track transcription, translation & coupling 3/n www.nature.com/articles/s41...

Just published: My (Janosch Hennig) view on the current capabilities of AF3 and similar for RNA and protein-RNA complex structure prediction plus a bit of forward looking: doi.org/10.1002/cbic...

Check it out! Another novel RNA modification - ADP-ribosylation - that was previously only known on proteins. A cousin to #glycoRNA 👏 www.nature.com/articles/s41...

#cryoET of Mycoplasma pneumoniae Chloramphenicol-bound ribosomes at a global 3.0 Å resolution www.nature.com/articles/s41...

Excited to share our new work on the earliest steps of Pol-III transcription: We provide structural and kinetic insights into tRNA promoter engagement by yeast transcription factor TFIIIC ! Cool collaboration with the Müller and Eustermann Labs @embl.org ! academic.oup.com/nar/advance-...

EMBL Group Leader @olivierduss.bsky.social and his research team discovered how two molecular machines in bacteria work together and watched their interactions as a real-time movie. Discover how they put snapshots in motion 👉 www.embl.org/news/science... #MolBiol 🧪 @natureportfolio.bsky.social

First paper of our lab today @natureportfolio.bsky.social by Nussi! We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping! @embl.org #RNAbiology #RNASky t.co/a24Xxcxdo0

Congratulations, Olivier Duss, Simone Köhler, and Eva Kowalinski! 👏 The three EMBL Group Leaders have received ERC Consolidator Grants #ERCCoG for their innovative research projects aimed at understanding fundamental cellular mechanisms. #MolBiol 🧪👇 Read more here: www.embl.org/news/awards-...

Very grateful to get support from the #ERC Consolidator grant! -to study how #transcription, #translation and #DNA repair cooperate -combining #single-molecule #microscopy in vitro & live cells and #cryoET -obtaining a real-time movie 🎥 🎞️ -hiring soon @embl.org! www.embl.org/news/awards-...

Excited to share our study led by @SakenovaNazgul! We used chemical genetics to identify and understand cross-resistance & collateral-sensitivity (CS) between antibiotics and reduced AMR development with CS drug pairs @embl.org with @camille_goemans @EPFL_en www.nature.com/articles/s41...

Happy to share the website of RiboMod2025, the "Conference on Ribosomal RNA modifications and snoRNAs" in Bologna June 12-13, 2025 is up at events.unibo.it/ribomod2025 Stay tune for more infos! #RNA #Ribosome #snoRNA #Eiptranscriptomics

I'm excited to share the preprint for the first chunk of my PhD work! We combined DMS structure probing with nascent RNA enrichment to report high-resolution, dynamic structures of transcripts just after synthesis - inside cells. @karlaneugebauer.bsky.social www.biorxiv.org/content/10.1...

Are you a scientist working or interested in RNA Translation? Join our starter pack and share ideas, methodologies and tips to advance our knowledge in how life came to be! #RNA #ribosome go.bsky.app/VN78eTo

Excited to share our new study with the Müller and @SchullerJm labs, online @nature: https://www.nature.com/articles/s41586-022-04971-z This is T. kivui, an anaerobic bacterium. It uses hydrogen energy to store #CO2. How does it do it? #CryoET revealed membrane-anchored bundles of...

Interesting findings by the Zarnack and König labs: www.cell.com/molecular-ce... #RNAbiology

EMBL is Europe’s life sciences laboratory. 🧬🧪 At our sites in Barcelona,​​ Grenoble, Hamburg, Heidelberg, Hinxton, and Rome, we seek to understand life in context, from molecules to ecosystems. 🔬🌍 Follow us for our latest news and updates about research, training, services and more. www.embl.org

Exciting highlights of the recent complex life of #RNA symposium @embl.org featuring Matt Disney, Juan Valcarcel, @lapassmore.bsky.social, Herve Le Hir, Andreas Meyer, Yiliang Ding, Seitz Herve, Maria Hondele, @juliusbrennecke.bsky.social, Bahareh Torkzaban www.embl.org/news/science...

Check it out! The RNA Society 2025 Meeting Site is now live! Registration will open in January RNASociety Note the fabulous artwork by former EmoryBCDB student Dr. Carly Lancaster- make your plans now to join us in San Diego May 27-June 1, 2025