What happens to transcription upon oxidative DNA damage? 🧬💥 RNAPII halts instantly within genes ⛔️ and even more surprisingly: It restarts from where it stopped without leaving the DNA template 🚦 👀📄 How does this happen? Find out in our new preprint👇 www.biorxiv.org/cgi/content/...

If said women work for your competitors, I guess maybe

Less than an hour later the first preprint was already paired to q.e.d! 🔥🍷

Starting your own lab is exciting—but challenging. Join our GBM Young Investigator leadership workshop in Regensburg, April 13–16th, 2026. Professional coaching, peer networking & practical tips for new PIs. Apply by Nov 30, 2025. 👉https://yi-workshop.gbm-online.de/yi-workshop-2.html

As a mindfulness advocate, it is important to stress that meditation can have downsides if approached carelessly. It’s crucial to prepare and practice moderation. If meditation causes distress, that’s okay! Adjust your approach to your mindfulness journey. journals.sagepub.com/doi/10.1177/...

🚀 Exciting news! ERC Synergy Grant of €8.5 million to Sara Wickström @sarawickstrom.bsky.social, Daniel St Jonston @gurdoninstitute.bsky.social and Ewa Paluch @universitypress.cambridge.org! This highly interdisciplinary project will boost our understanding of tissue biology. #ERCSyG @erc.europa.eu

Secretome translation shaped by lysosomes and lunapark-marked ER junctions www.nature.com/articles/s41...

Just 1 week to apply! 4 year @erc.europa.eu funded PhD position working in an interdisciplinary team to study #culturalEvolution as a process of reuse, recombination, and creative re-engineering of past solutions. Details 👉 hmc-lab.com/ERCPhDCultur... 🙏Please share!

www.biorxiv.org/content/10.1... Check this from @campaslab.bsky.social and @jesseveenvliet.bsky.social

Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass... I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands) #WesternBlot #cellsky

Language models cannot reliably distinguish belief from knowledge and fact #AI Failure to make such distinctions can mislead diagnoses, distort judicial judgments and amplify misinformation. www.nature.com/articles/s42...

Mamdani: "New York will remain a city of immigrants, a city built by immigrants, powered by immigrants, and as of tonight, led by an immigrant."

I think a thing we'll learn tonight is that people fucking hate what is going on and they will straight ticket vote against anyone involved in starving people while pillaging the country and kidnapping their neighbors. I don't think it matters at all who that person is.

Check this from the talented and unimitable Bibli lab "Nuclear cystine oxidation boosts acetyl-CoA, decorating histones and opening chromatin" www.cell.com/cell-metabol...

Good Sunday, mitolovers. Here is a wonderful selection of papers in #cancermetabolism and #mitochondrialbiology: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading "Coming back to where you started is not the same as never leaving."-Terry Pratchett

📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Integrative Structure Biology with a focus on in situ structural biology using cryo-electron tomography (cryo-ET) and related methods. More details ➡️ tinyurl.com/brswbymu

🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny. #ProtistsOnSky #SciComm #SciSky www.cell.com/cell/fulltex...

The Wilkinson Lab is open for science! @mskcancercenter.bsky.social 🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬 annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)

We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word www.scripps.edu/news-and-eve...

Wow

Congratulations @karalmckinley.bsky.social & lab on their groundbreaking recent preprint establishing + characterizing a chemically inducible model of menstruation in mouse: www.biorxiv.org/content/10.1... My jaw dropped when I heard this presented earlier this year. Incredible.

1/ Excited to share our new study with @brumbaugh-lab.bsky.social, out in @natbiotech.nature.com! P-bodies selectively sequester RNAs encoding cell fate regulators, often from the preceding developmental stage. Releasing these RNAs can drive changes in cell identity. 🧵 www.nature.com/articles/s41...

www.sciencedirect.com/science/arti... From Aguirre lab

This will bleed into Europe as well in 3 to 5 years since the budget is getting cut every year

Another amazing study by @danielibrahim.bsky.social www.biorxiv.org/content/10.1...

What is a promoter? And how does it work? We very happy to share our latest work trying to understand enhancer-promoter compatibility. I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters www.biorxiv.org/content/10.1...

Struggling to get papers into review? Test this out from @odedrechavi.bsky.social I beta tested the earlier version, and it worked really well..

"m6A in the coding sequence: linking deposition, translation and decay" by Kathi Zarnack (@zarnack-group.bsky.social) & colleagues "This review explores [m6A in] mRNA decay, with a focus on the newly discovered CDS–m6A decay (CMD) pathway..." Read it here: authors.elsevier.com/sd/article/S...

The journal Science covers the UC spyware saga. The UC administrators’ policy assurances are like saying one does not have to lock one’s car because it is illegal for someone to steal the car or its contents. #highereducation 🧪⚛️🔭 #academicsky www.science.org/content/arti...

check this beauty from @dandergassen.bsky.social

www.sciencedirect.com/science/arti... Organellar pH as an emerging vulnerability to exploit in cancer Congrats to @cosimocommisso.bsky.social

When Everything Is Fake, What’s the Point of Social Media? time.com/7326718/sora... @elisabethbik.bsky.social

check this from the talented @mpodobnik.bsky.social www.biorxiv.org/content/10.1...

Paper alert! doi.org/10.1038/s443... - "A scheduler for rhythmic gene expression". We show how 9 txn factors suffice for rhythmic gene expression of thousands of genes with any phase or amplitude in #Celegans larvae (and also look at the tissues where oscillations happen) 1/n

#GastrulationReloaded was a FANTASTIC , loaded with exciting discoveries. It went beyond gastrulation because what happens before & after is obviously connected. Still, not half the people who should be there were. @jeromegros.bsky.social largely funded the conference 👏. @embo.org should reconsider

A university that signs the “compact” is one that acknowledges its own inability to compete and succeed based talent and merit. It would signal insecurity and mediocrity to current and future students and faculty. Say no. Recruit the best people, protect their freedom and support their hard work.

Virus driven Disruption of Transcription Termination (DoTT) generated cellular Z-RNAs are bona fide ZBP1 ligands driving cell death as a host response to counter viral disruption of the cellular transcriptional machinery @nature.com @foxchasecancer.bsky.social www.nature.com/articles/s41...

Happy to have started as an @hhmi.org Freeman Hrabowski Scholar! Incredibly grateful for this opportunity and am excited for some very cool new directions! We are *HIRING*, especially postdocs! Please reach out if you’re interested in uterine and pregnancy biology. Please repost!

The following is REAL footage from Portland, 2025. Viewer discretion is advised.

"Immigrants, we get the job done" www.economist.com/graphic-deta...

I really enjoyed recording "Big Biology"! We talked about A LOT of things, including my new passion project qedscience.com (check it out, more on this and big announcement coming soon:) 😍😍😍🔥🔥⚡️⚡️@bigbiology.bsky.social open.substack.com/pub/bigbiolo...

A Nobel-winning scientist of great modesty and humour, John Gurdon died on 7 Oct. Not only did he make a discovery that laid the foundations for stem cell research, he also created one of the best environments for research at the Wellcome/CRUK Gurdon Institute wellcome.org/news/sir-joh...

Query from Slack: Looking for people with experience in proximity labelling in zebrafish? Considering using miniTurbo instead of BioID or APEX, what do the community think of it? Also looking for anybody that has experience with targeting labeling enzymes to the ER/secretory pathway? #AskZebrafish