“Just because you are offended doesn’t mean you are right.” Ricky Gervais

Our new preprint, full of exciting data, is now available. Have a look! QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5ʹ splice sites www.biorxiv.org/content/10.1...

www.cell.com/cell/fulltex... Tour de force spearheaded by brilliant Marko Jovanovic and colleagues!

An Optimized SP3 Sample Processing Workflow for In-Depth and Reproducible Phosphoproteomics pubs.acs.org/doi/10.... --- #proteomics #prot-paper

Researchers are making ever more sophisticated mini organs in the lab — and now they can grow their own blood vessels go.nature.com/4nNF3ri

One day, scientists will discover Adobe InDesign/Affinity Publisher/… for figure assembly and our lives will be much easier…

A review of the history of protein-RNA friendship.

Germany of the 21st century: A place where there is a massive problem for all major personal parcel delivery companies to deliver an order. #OrdnungMussSein

Feedback without specifics is not feedback. It’s frustration.

'Night science' is what you do when you're not sure what's the question.

Dream big. Dare to fail. Fuck dull, incremental science.

We have several open postdoc positions! We do computational biology 🧬🖥️ and deep learning to understand the genomics of genome instability and (somatic) genome evolution in ageing and cancer. Interested? 👉🏻 more details: tu-dresden.de/cmcb/biotec/...

Ribosomes on an mRNA molecule are like: youtu.be/7wm-pZp_mi0?...

I visited the lab where I did my PhD today. They moved two floors upstairs since I left in 2020, they have got new stuff, many new students and postdocs. Yet, there are still boxes with my name around, and they are about to finish the 3C protease I purified back then. 🧡 #ProteinPutification #eIF3

Every. Time.

- Return to work after attending #TCTeAC - Make yourself a cappuccino - Reflect on all the wonderful things in life - Clear out those emails and embrace happiness

The following day after coming back from #TCTeAC

If any #TCTeAC survivors are staying in Prague tonight or longer, feel free to DM me for recommendations, tricks, and survival tips. Or we can have a last beer together this evening. #AllRoadsLeadToPub

#TCTeAC ... and that was all, folks! Thank you, it was fantastic.

The fewer charts, the more interest. 🤔 I am grateful to everyone who stopped by my poster and discussed the cell fate decisions and cardiac differentiation with me. #AffinityDesigner #ThePosterToEndAllPosters #TCTeAC

People at #TCTeAC recognise me for taking speakers off the stage now. But there’s more (less?!) to come. Stay tuned! Poster 57.

@odedrechavi.bsky.social says he wants to change science for the better. How? I’m still not quite sure. But 1.5 days into #TCTeAC, the plan seems to involve, among other things, walk-up songs, jumping, dancing, and a hefty serving of joy.

Follow me for my fitness tips. 💪 #TCTeAC

A question for PřF UK alums/students: When did they turn Velká geologická into a bathroom? 🤔 #TCTeAC

Got too many ribosomes? Wanna get rid of them? DM me. #TCTeAC

UCUeAC #RNArules #TCTeAC

All yeast strains are beautiful. #TCTeAC

Power Corrupts. PowerPoint Corrupts Absolutely. Corrupted PowerPoint slides support creativity. #TCTeAC

#TCTeAC FTW

Here's one of the interactive sessions today. I really think all conferences should have these!

When you finish a concert with an orchestra and now you can catch a plane to attend #theconferencetoendallconferences youtube.com/clip/UgkxCbr...

Concentric doughnut charts: because pie charts weren't bad enough.

Antibodies don't work. NLRP3 is by far the most studied inflammasome — yet <30% of commercial antibodies were specific. Only 4 of 14 tested antibodies detected NLRP3 specifically. Antibodies must be validated before use. Full report by @ycharos.bsky.social : zenodo.org/records/1162...

Germany of the 21st century, a place where it would be easier to pay with silver bars than with a Visa/MasterCard debit card issued by a German fucking bank.

The cover of the April issue of @cp-trendspharma.bsky.social. Gregory Howard and William Tansey review the current status, challenges, and future prospects of cancer treatments that target the ribosome. Aberrant ribosome production and function are hallmarks of cancer.

AlphaFold is amazing but gives you static structures 🧊 In a fantastic teamwork, @mcagiada.bsky.social and @emilthomasen.bsky.social developed AF2χ to generate conformational ensembles representing side-chain dynamics using AF2 💃 Code: github.com/KULL-Centre/... Colab: github.com/matteo-cagia...

Ordnung muss nicht sein. www.welt.de/politik/deut...

My guidelines for exploratory data analysis

When you forget to make aliquots for your students.

Where do proteins go in cells? Next-generation methods map the molecules’ hidden lives www.nature.com/artic... --- #proteomics #prot-paper

When used carelessly, animation can distract from data visualizations. Check out these best practices for delivering better animations in data visualizations.

Often, I find myself pondering which "F" in "FFM" stands for "filth." I am increasingly convinced that both do.

After seven years of development, we present the highly general human ventricular cardiomyocyte T-World www.biorxiv.org/content/10.1... It represents excitation-contraction coupling, contractility, sympathetic signalling, sex differences, and it is suitable for multiscale studies. 1/X

Finally, there's a scientific conference where I can really put my canoeing skills to good use!

Running out of popcorn.

Characterizing the omics landscape based on 10,000+ datasets www.nature.com/artic... --- #proteomics #prot-paper