Anna Poetsch
@apoetsch.bsky.social
📤 2288
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Computational Biologist at TU Dresden. Interested in how genomes encode their own stability.
Congratulations
@vakil-takhaveev.bsky.social
@sturlalab.bsky.social
and everyone else involved. It was really a pleasure to play a small part in it. I am looking forward to celebrating the next time we meet!
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5 days ago
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Anna Poetsch
Javier Santoyo
7 days ago
Click-code-seq reveals strand biases of DNA oxidation and depurination in human genome.
#DNAoxidation
#HumanGenome
@natchembio.nature.com
www.nature.com/articles/s41...
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Anna Poetsch
Benjamin Schuster-Böckler
19 days ago
I am looking to get my hands on some
#Illumina
5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
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It was a pleasure to talk Genome Stability for a few days with the DFG - FOR5504 for. It is really exciting to see the community in and around Cologne looking for genome stability in whole organisms and the context of the sequence. I am excited about what else is going to come.
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about 1 month ago
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Me: I got a new type of compliment from an audience member: "Your talk was so Gen Z" My lab: This was not a compliment... Me: 🥲 (but..., but..., I still think it was meant to be one...)
about 1 month ago
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I am happy to share some thoughts on using AI to generate viruses (in German).
www.spiegel.de/wissenschaft...
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(S+) Künstliche Intelligenz: KI-designtes Virus tötet Kolibakterien
US-Forscher haben mithilfe von künstlicher Intelligenz Viren hergestellt und ihnen bestimmte Eigenschaften gegeben, weltweit sind sie damit wohl die Ersten. Die Möglichkeit KI-generierten Lebens schei...
https://www.spiegel.de/wissenschaft/technik/kuenstliche-intelligenz-ki-designtes-virus-toetet-kolibakterien-a-a9d4858f-7200-48d1-875c-ab859576a153
about 1 month ago
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Anna Poetsch
The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German).
www.swr.de/leben/gesund...
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Die ersten KI-generierten Viren als Hoffnung im Kampf gegen resistente Bakterien
Forschende aus Stanford haben erstmals Viren entwickelt, die von einer KI entworfen wurden. Einige dieser KI-Viren konnten antibiotikaresistente Bakterien infizieren und abtöten - ein möglicher Durchb...
https://www.swr.de/leben/gesundheit/erste-ki-generierte-viren-als-hoffnung-im-kampf-gegen-resistente-bakterien-100.html
about 1 month ago
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There is a new Master of Physics of Life in the house. Congratulations, Adnan! Well done! It was really a superb Defense!
@poldresden.bsky.social
about 1 month ago
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The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German).
www.swr.de/leben/gesund...
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Die ersten KI-generierten Viren als Hoffnung im Kampf gegen resistente Bakterien
Forschende aus Stanford haben erstmals Viren entwickelt, die von einer KI entworfen wurden. Einige dieser KI-Viren konnten antibiotikaresistente Bakterien infizieren und abtöten - ein möglicher Durchb...
https://www.swr.de/leben/gesundheit/erste-ki-generierte-viren-als-hoffnung-im-kampf-gegen-resistente-bakterien-100.html
about 1 month ago
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I am happy to share some thoughts on using AI to generate viruses (in German).
www.spiegel.de/wissenschaft...
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(S+) Künstliche Intelligenz: KI-designtes Virus tötet Kolibakterien
US-Forscher haben mithilfe von künstlicher Intelligenz Viren hergestellt und ihnen bestimmte Eigenschaften gegeben, weltweit sind sie damit wohl die Ersten. Die Möglichkeit KI-generierten Lebens schei...
https://www.spiegel.de/wissenschaft/technik/kuenstliche-intelligenz-ki-designtes-virus-toetet-kolibakterien-a-a9d4858f-7200-48d1-875c-ab859576a153
about 1 month ago
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Dear CRC TRR 341, thanks for having me. It was fascinating to learn more about the genomes of plants in their ecological context!
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about 1 month ago
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Anna Poetsch
Craig Anderson
3 months ago
Would you like to do some unique experiments in cancer genomics and mutagenesis, in beautiful Munich? Well then apply for this PhD position:
jobs.dkfz.de/en/jobs/1679...
You'll learn a lot and it'll be fun and interesting!
#DKTK
@dkfz.bsky.social
@lmumuenchen.bsky.social
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PhD Student in Mutational Processes Driving Somatic Evolution
https://jobs.dkfz.de/en/jobs/167996/phd-student-in-mutational-processes-driving-somatic-evolution
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Exciting to see the
@grunewaldlab.bsky.social
finding new target candidates against metastases of Ewing sarcoma. It makes one wonder how general this pathway disruption might be and whether it may work with other sarcomas or metastatic cancers in general… 🤔
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3 months ago
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We are happy to present a new paper on gastric tumour evolution in response to peri-operative chemotherapy.
www.biorxiv.org/content/10.1...
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Tumor clone dynamics in gastro-esophageal cancer organoids reveal a non-genetic memory of neoadjuvant chemotherapy via downregulation of NFκB signaling
Adenocarcinomas of the gastroesophageal junction exhibit genetic and non-genetic heterogeneity that impact clinical outcomes, though the underlying mechanisms behind drug resistance remain poorly unde...
https://www.biorxiv.org/content/10.1101/2025.07.29.667467v1
3 months ago
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We are happy to present a new paper on the sequence dependence of 🧬-double strand breaks.
www.biorxiv.org/content/10.1...
🧵 1/4
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Using the DNA language model, GROVER, to parse sequence and epigenetic effects on genome stability
Genome stability is shaped by DNA sequence and epigenomic context, but their relative contributions to double-strand break (DSB) sensitivity remain unclear. We show that the DNA language model, GROVER...
https://www.biorxiv.org/content/10.1101/2025.07.23.666402v1
3 months ago
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Anna Poetsch
The Company of Biologists
4 months ago
This week, we are highlighting Helena Jambor, a prolific contributor to our community sites
@the-node.bsky.social
and
@focalplane.bsky.social
, as an extraordinary biologist.
#100biologists
@helenajambor.bsky.social
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Anna Poetsch
TUD | Center for Molecular and Cellular Bioengineering (CMCB)
4 months ago
🚨
#JobAlert
. please share: The DRESDEN-concept Genome Center (DcGC) 🧬
@dcgenomecenter.bsky.social
is looking for the new Head of Facility! 🗓️ Deadline for applications: August 11 More information here ➡️
tud.link/fz5hr8
@tudresden.bsky.social
@mpi-cbg.de
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We have several open postdoc positions! We do computational biology 🧬🖥️ and deep learning to understand the genomics of genome instability and (somatic) genome evolution in ageing and cancer. Interested? 👉🏻 more details:
tu-dresden.de/cmcb/biotec/...
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Open positions
We are looking for Postdocs! If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …
https://tu-dresden.de/cmcb/biotec/forschungsgruppen/poetsch/jobs
5 months ago
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Anna Poetsch
Danny
5 months ago
open.spotify.com/playlist/1As...
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Woodstock.bio2 & Night Science 2025 playlist
Playlist · Vojtěch Svoboda · 99 items · 2 saves
https://open.spotify.com/playlist/1AstWGHZ2AMXvqEFR6JJIR?si=ff79e7b6bf0d4aab&nd=1&utm_medium=organic&product=open&%24full_url=https%3A%2F%2Fopen.spotify.com%2Fplaylist%2F1AstWGHZ2AMXvqEFR6JJIR%3Fsi%3Dff79e7b6bf0d4aab&feature=organic
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Anna Poetsch
Elise Cutts
5 months ago
@odedrechavi.bsky.social
says he wants to change science for the better. How? I’m still not quite sure. But 1.5 days into
#TCTeAC
, the plan seems to involve, among other things, walk-up songs, jumping, dancing, and a hefty serving of joy.
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@helenajambor.bsky.social
Making a point about the importance of data visualization.
#theconferencetoendallconferences
#TCTEaC
5 months ago
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Anna Poetsch
Stein Aerts
5 months ago
The deadline for the VIB.AI group leader positions is approaching - send in your CV and short research plan before 14th June to start your BioML research lab in Leuven or Ghent
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Anna Poetsch
Marketa Tomkova
6 months ago
We are recruiting! Senior postdoc in computational cancer genomics/epigenomics
@ludwigcancer.bsky.social
@ox.ac.uk
. Lead research into epigenetic drivers of secondary AML with rich omics data + strong clinical/wet-lab collaborations.
cutt.cx/YUoB
We look forward hearing from you!
#epigenetics
#jobs
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Anna Poetsch
Are you interested in combing machine learning and 🧬 language models with multi-omics data to study somatic genome evolution? We have several open postdoc positions and look forward to hearing from you!
tu-dresden.de/cmcb/biotec/...
🧬🖥️
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Open positions
We are looking for Postdocs! If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …
https://tu-dresden.de/cmcb/biotec/forschungsgruppen/poetsch/jobs
7 months ago
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Anna Poetsch
TUD | Biotechnology Center (BIOTEC)
7 months ago
🚨
#JobAlert
Postdoc positions in
@apoetsch.bsky.social
group at BIOTEC. Combine
#AI
and
#LLM
with
#omics
data to study
#genomics
. More info ⬇️⬇️
add a skeleton here at some point
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Are you interested in combing machine learning and 🧬 language models with multi-omics data to study somatic genome evolution? We have several open postdoc positions and look forward to hearing from you!
tu-dresden.de/cmcb/biotec/...
🧬🖥️
loading . . .
Open positions
We are looking for Postdocs! If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …
https://tu-dresden.de/cmcb/biotec/forschungsgruppen/poetsch/jobs
7 months ago
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I am excited to see the first Johannstadt Campus Symposium on Computational Biology start. Looking forward to 4 exciting talks and a 🍻 hour. If you are around, please drop by.
8 months ago
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Anna Poetsch
8 months ago
I am aware that we are annoying some people in the US with the
#Woodstockbio2025
. But, see this as an opportunity to
#standupforscience
. After all, the event was catalysed by
#Trumpcellation
of support for a non-profit organization which booked the
#YMCAcampsite
.
woodstock.img.cas.cz/registration/
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Having participated last year, I can say that this workshop is really worth it! So if you plan to apply for a professorship around genetics in Germany within the next few years, sign up!
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10 months ago
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I am going to go to Paris several times this year. The timing for this could not be better :-) Time to brush up on some French 🇫🇷
add a skeleton here at some point
10 months ago
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Anna Poetsch
Philip Oldfield
10 months ago
It’s over 1,000km from Berlin to Paris There’s now a direct daytime train between them, that takes 8 hours and costs just €59. Leave at 10am, arrive 6pm. And… it’s just 1% the carbon emissions of the equivalent flight
www.euronews.com/travel/2024/...
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High-speed Paris-Berlin daily train service debuts
The route is the first directly linking the two capitals' city centres.
https://www.euronews.com/travel/2024/12/13/high-speed-train-from-paris-to-berlin-to-launch-this-winter-with-daily-connections-from-59
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Anna Poetsch
Nick Graham
10 months ago
Still hope for coral reefs. Using 28-years of data in Seychelles, we find reefs recovering 4-5 years faster from the 2016 bleaching event, than they did after 1998. Also, a reef that had regime-shifted to macroalgae for over 15 years, is recovering to coral.
onlinelibrary.wiley.com/doi/10.1111/...
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Increased resilience and a regime shift reversal through repeat mass coral bleaching
Assessing coral reefs across the inner Seychelles islands, using a 28-year dataset, we document faster coral recovery from the 2016 than the 1998 marine heatwave events. Further, a reef that had regi....
https://onlinelibrary.wiley.com/doi/10.1111/ele.14454
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Taking a break from 🧬 👩🏼💻 and went home. I’m still at the center of things, or at least, of the European Union 🇪🇺.
11 months ago
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Anna Poetsch
Andrew Steele
11 months ago
The days will start getting longer… …wait for it… …now! Winter solstice 2024, December 21st, 09:20 UTC
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Welcome
@cmcb-tud.bsky.social
! I am happy to see you over here at 🦋!
11 months ago
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Evo, a new 🧬 language model got published yesterday.
www.science.org/doi/10.1126/...
I am happy to have contributed some comments about it for the German speaking press:
www.sciencemediacenter.de/angebote/ki-...
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KI-Modell analysiert und generiert DNA-Strukturen
https://www.sciencemediacenter.de/angebote/ki-modell-analysiert-und-generiert-dna-strukturen-24165
12 months ago
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There is a new 🧬 language model around. Evo learns on 2.7 Mio prokaryotes and phages and can be used to address questions around DNA, RNA, and Proteins.
www.science.org/doi/10.1126/...
🖥️🧬
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Sequence modeling and design from molecular to genome scale with Evo
The genome is a sequence that encodes the DNA, RNA, and proteins that orchestrate an organism’s function. We present Evo, a long-context genomic foundation model with a frontier architecture trained o...
https://www.science.org/doi/10.1126/science.ado9336
12 months ago
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Whom can I follow for news in easy Japanese? 🎌
12 months ago
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Anna Poetsch
Tatiana Moiseeva
12 months ago
ok, I tried to make a starter pack on genome stability/DNA replication/DNA repair etc. Sorry if I couldn't find someone, please nominate yourself and your colleagues in comments or DMs, looking forward to connecting with everyone!
go.bsky.app/9jdDNxG
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