CiFi: accurate long-read chromosome conformation capture with low-input requirements. #HiFi #LongRead #Sequencing @natcomms.nature.com 🧪🧬 🖥️ www.nature.com/articles/s41...

Search-and-remove genome editing allows selection of cells by DNA sequence. #GenomeEditing #CellSelection @natcomms.nature.com 🧪🧬 🖥️ www.nature.com/articles/s41...

Mapping single-cell diploid chromatin fiber architectures using DAF-seq. #SingleCell #ChromatinFiberArchitecture #Sequencing #Genomics @natbiotech.nature.com 🧪🧬 🖥️ www.nature.com/articles/s41...

Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets.#SpatialTranscriptomics #StandardizedMetrics #DataRepository #BestPractices #OpenSourceSoftware #Genomics #Bioinformatics @natbiotech.nature.com www.nature.com/articles/s41...

Whole-genome landscapes of 1,364 breast cancers. #WGS #BreastCancer #Genomics @nature.com www.nature.com/articles/s41...

Insights into natural neocentromere evolution from a cattle T2T X chromosome. #CattleGenome #T2T #HaplotypeResolvedGenome #Centromeres #Genomics @natcomms.nature.com 🧪🧬 🖥️ www.nature.com/articles/s41...

Long-read metagenomics reveals phage dynamics in the human gut microbiome. #GutMicrobiome #Phages #LongReads #Sequencing #Genomics @nature.com 🧪🧬 🖥️ www.nature.com/articles/s41...

A bioinformatic survey of RNA isoform diversity and expression across 9 GTEx tissues using long-read sequencing data. #RNAisoforms #GTEx #LongReads #Sequencing #Genomics #Bioinformatics #BMCgenomics link.springer.com/article/10.1...

Genome annotations matter: characterizing Ensembl hg38 annotations from 2014 to 2023. #mRNA #GenomeAnnotation #EnsemblGenes #Isoforms #BMCgenomics link.springer.com/article/10.1...

Plate-based 10X Genomics-compatible single-cell RNA-sequencing based on Smart-seq3xpress. #SingleCell #scRNAseq #PlateBasedAssay #10X #Genomics #BMCgenomics link.springer.com/article/10.1...

SeqForge: a scalable platform for alignment-based searches, motif detection, and sequence curation across meta/genomic datasets. #Metagenomics #AlignmentBasedSearches #Genomics #Bioinformatics #BMCbioinformatics link.springer.com/article/10.1...

MOV&RSim: computational modelling of cancer-specific variants and sequencing reads characteristics for realistic tumoral sample simulation. #DataSimulation #CancerVariants #SequencingReads #ComputationalModelling #BMCBioinformatics 🧪🧬 🖥️ link.springer.com/article/10.1...

TaxaPLN: a taxonomy-aware augmentation strategy for microbiome-trait classification including metadata. #Microbiome #DataAugmentation #GenerativeModel #BMCbioinformatics 🧪🧬 🖥️ link.springer.com/article/10.1...

Universal noninvasive prenatal diagnosis for monogenic disorders using cell-free plasma DNA. #cfDNA #MonogenicDisorders #PrenatalDiagnosis #GenomeMedicine link.springer.com/article/10.1...

Pangenomic structural variant patterns reflect evolutionary diversification in Brassica napus. #StructuralVariants #Pangenomes #BrasicaNapusGenome #PlantGenomics #Bioinformatics #GenomeBiology 🧪🧬 🖥️ link.springer.com/article/10.1...

HGMT: a database of human gut microbiota for tumors and immunotherapy response. #GutMicrobiota #TumorSample #Metagenomics #ImmunotherapyTreated #GenomeBiology 🧪🧬 🖥️ link.springer.com/article/10.1...

Long-read structural variant discovery and targeted short read genotyping enables population scale characterization of structural variation in rhesus macaques. #SVs #RhesusMacaqueGenomes #LonngRead #Sequencing #Genomics #Bioinformatics #GenomeBiology 🧪🧬 🖥️ link.springer.com/article/10.1...

Evaluation of false positive and false negative errors in targeted next generation sequencing. #TargetNGS #Sequencing #FalsePositives #FalseNegatives #Genomics #Bioinformatics #GenomeBiology link.springer.com/article/10.1...

Xenbase: 25 years of integrating molecular and biomedical data from Xenopus. #Xenopus #MolecularData #BiomedicalData #Genetics 🧪🧬 🖥️ academic.oup.com/genetics/adv...

The value of structural variants to conservation genomics in the pangenome era. #StructuralVariants #SVs #Bioinformatics #Genomics #ConservationGenomics #Pangenomes #JournalOfHeredity academic.oup.com/jhered/advan...

MeTAline: enabling reproducible and scalable metagenomic analyses. #MetagenomicAnalysis #ShotgunMetagenomics #Snakemake #Containers #HPC #Bioinformatics #Genomics #NARgenomicsAndBioinformatics 🧪🧬 🖥️ academic.oup.com/nargab/artic...

A Telomere-to-Telomere Diploid Reference Genome and Centromere Structure of the Chinese Quartet. #HumanGenome #ReferenceGenome #ChinesePopulation #T2T #Genomics #GenomicsProteomicsAndBioinformatics 🧪🧬 🖥️ academic.oup.com/gpb/advance-...

The effects of bioinformatics preprocessing on cell-free DNA fragment analysis. #cfDNA #Bioinformatics #DataProcessing #FragmentAnalysis @gigascience.bsky.social 🧪🧬 🖥️ academic.oup.com/gigascience/...

Quantitative detection of DNA methylation from nanopore sequencing data without raw signals. #DNAmethylation #Nanopore #Sequencing #Bioinformatics @gigascience.bsky.social academic.oup.com/gigascience/...

NApy: Efficient Statistics in Python for Large-Scale Heterogeneous Data with Enhanced Support for Missing Data. #Statistics #Python #MissingData #HeterogeneousData #Bioinformatics @gigascience.bsky.social 🧪🧬 🖥️ academic.oup.com/gigascience/...

RNA-SeqEZPZ: A Point-and-Click Pipeline for Comprehensive Transcriptomics Analysis with Interactive Visualizations. #RNAseq #DataAnalysis #TranscriptomicsAnalysis #Visualization #Genomics #Bioinformatics @gigascience.bsky.social 🧪🧬 🖥️ academic.oup.com/gigascience/...

proGenomes4: providing 2 million accurately and consistently annotated high-quality prokaryotic genomes. #ProkaryoticGenomes #AnnotatedGenomes #Bioinformatics #Genomics #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

Giant chromosomes of a tiny plant - the complete telomere-to-telomere genome assembly of the simple thalloid liverwort Apopellia endiviifolia (Jungermanniopsida, Marchantiophyta). #LiverwortsGenome #PlantGenomics #LargeChromosomes @gigascience.bsky.social 🧪🧬 🖥️ academic.oup.com/gigascience/...

RMPore: a comprehensive database of single-molecule RNA modifications detected by Nanopore direct RNA sequencing. #RNAmodifications #Nanopore #DirectRNAseq #Bioinformatics #Genomics #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

EMBL’s European Bioinformatics Institute (EMBL-EBI) in 2025. #Bioinformatics #Genomics #PublicBiomolecularData #EBI #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

The UCSC Genome Browser database: 2026 update. #GenomeBrowser #UCSC #Genomics #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

Genenames.org: the HGNC and PGNC resources in 2026. #GenesNomenclature #Genomes #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

SomaMutDB 2.0: A comprehensive database for exploring somatic mutations and their functional impact in normal human tissues. #SomaticMutations #HumanTissues #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

TE-SCALE: a comprehensive database for exploring transposable element expression across human cancers at single-cell resolution. #TransposableElements #TE #HumanCancer #SingleCells #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

Ensembl 2026. #Genomes# Annotation #Genomics #Bioinformatics #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

JoGo 1.0: the ACTG hierarchical nomenclature and database covering 4.7 million haplotypes across 19,194 human genes.#GeneticStandard #GeneHaplotypes #Bioinformatics #Genomics #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

PolyA_DB v4: systematic polyA site identification and isoform annotation in human and mouse genomes using 3′ end and long-read sequencing data.#PolyA #IsoformAnnotation #Genomics #Bioinformatics #NAR @narjournal.bsky.social 🧪🧬 🖥️ academic.oup.com/nar/advance-...

PSQAN: a pipeline to prioritise novel and biologically relevant transcripts from long-read RNA sequencing. #LongReads #RNAseq #TranscriptPrioritisation @bioinfoadv.bsky.social 🧪🧬 🖥️ academic.oup.com/bioinformati...

Snappy: fast identification of DNA methylation motifs based on Oxford Nanopore reads. #DNAmethylation #BacterialDNA @nanoporetech.com #Sequencing #Bioinformatics #Genomics @bioinfoadv.bsky.social academic.oup.com/bioinformati...

Cleanifier: Contamination removal from microbial sequences using spaced seeds of a human pangenome index. #ContaminationRemoval #Kmers #HumanReads #Microbiome #Bioinformatics 🧪🧬 🖥️ academic.oup.com/bioinformati...

Raxtax: A k-mer-based non-Bayesian Taxonomic Classifier. #Kmers #Taxonomy #Bioinformatics 🧪🧬 🖥️ academic.oup.com/bioinformati...

SeqManager: A Web-Based Tool for Efficient Sequencing Data Storage Management and Duplicate Detection. #SequencingData #DataStorage #DuplicateDetection #Genomics #Bioinformatics @bioinfoadv.bsky.social academic.oup.com/bioinformati...

GREGoR: accelerating genomics for rare diseases. #ShortRead #LongRead #Sequencing #LRS #NGS #MultiOmics #Genomics #DataSets #RareDiseases @nature.com www.nature.com/articles/s41... 🧪🧬 🖥️

FroM Superstring to Indexing: a space-efficient index for unconstrained k-mer sets using the Masked Burrows-Wheeler Transform (MBWT). #Kmers #MaskedBWT #Genomics #Bioinformatics @bioinfoadv.bsky.social 🧪🧬 🖥️ academic.oup.com/bioinformati...

Accurate profiling of microbial communities for shotgun metagenomic sequencing with Meteor2. #MicrobialCommunities #Metagenomics #MicrobesProfiling #Microbiome microbiomejournal.biomedcentral.com/articles/10....

Y-chromosome alteration and its impact on cancer progression and metastasis. #YChr #Cancer #Metastasis #CellularMolecularBiologyLetters 🧪🧬 cmbl.biomedcentral.com/articles/10....

ZIPcnv: accurate and efficient inference of copy number variations from shallow whole-genome sequencing. #CNV #WGS #ShallowSequencing #Bioinformatics 🧬 🖥️ academic.oup.com/bioinformati...

Synteny plot quality control with SyntenyQC. #SyntenyPlots #Grnomivd #Bioinformatics 🧬 🖥️ academic.oup.com/bioinformati...

Target and Biomarker Exploration Portal for Drug Discovery. #BiomarkerExploration #DrugDiscovery #NetworkAnalysis #LLMs #Bioinformatics 🧬 🖥️ academic.oup.com/bioinformati...

Spider: a flexible and unified framework for simulating spatial transcriptomics data. #SpatialTranscriptomics #DataSimulation #Genomics #Bioinformatics 🧬 🖥️ academic.oup.com/bioinformati...