Shawn Baker
@sandiegomics.bsky.social
š¤ 867
š„ 186
š 92
Genomics consultant/advisor/investor
https://sandiegomics.com
reposted by
Shawn Baker
Jonathan Wosen
19 days ago
Jeffrey Epsteinās tissue samples ignited a furor in the Harvard lab of George Church, reports
@mmolteni.bsky.social
in this
@statnews.com
exclusive. 13 years later, the whereabouts of the sex offenderās skin cells are a mystery
www.statnews.com/2026/02/24/e...
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Jeffrey Epsteinās tissue samples ignited a furor in the Harvard lab of George Church
Exclusive: Harvard geneticist George Church knew more about Jeffrey Epstein's activities than he has previously said, before accepting new donations from the sex offender.
https://www.statnews.com/2026/02/24/epstein-cell-line-george-church-harvard-personal-genome-project/
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Illumina officially launches TruPath, their pseudo-long read sequencing kit (formerly called Constellation), at
#AGBT
#AGBT25
www.illumina.com/company/news...
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Illumina launches TruPath Genome, setting a new standard in genomic insight
https://www.illumina.com/company/news-center/press-releases/press-release-details.html?newsid=960974a8-171d-4c27-b2bd-82637ded77b1
19 days ago
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I have a little more detail and some commentary here -
sandiegomics.com/element-join...
add a skeleton here at some point
24 days ago
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Element reveals more information about their VITARI platform, a foray into the high-throughput sequencing market.
sandiegomics.com/element-join...
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Element Joins the High-Throughput Market with the VITARI Platform
Back at JPM Element teased that they would be coming out with the VITARI, a benchtop sequencer capable of generating whole genomes for $100. This would best Illuminaās list price of $200 with the Nā¦
https://sandiegomics.com/element-joins-the-high-throughput-market-with-the-vitari-platform/
24 days ago
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PacBioās very expensive foray into short read sequencing is now officially over. š
www.pacb.com/press_releas...
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PacBio Completes Sale of Short-Read Sequencing Assets - PacBio
MENLO PARK, Calif., Feb. 02, 2026 (GLOBE NEWSWIRE) ā PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the completion of the sale of sel...
https://www.pacb.com/press_releases/pacbio-completes-sale-of-short-read-sequencing-assets/
about 1 month ago
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reposted by
Shawn Baker
Keith Robison
about 1 month ago
Non-coding DNA's Alpha Moment š§¬š„ļø
omicsomics.blogspot.com/2026/02/non-...
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Non-coding DNA's Alpha Moment
I had been meaning to read the AlphaGenome paper on non-coding variant effect prediction from Google DeepMind which recently showed up in N...
https://omicsomics.blogspot.com/2026/02/non-coding-dnas-alpha-moment.html?m=1
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reposted by
Shawn Baker
Kevin Davies
4 months ago
Some close encounters with Jim Watson:
www.genengnews.com/topics/omics...
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DNA and the Unraveling of James Watson
A personal reflection on the life, legacy, and controversies of DNA co-discoverer James Watson, following his death at age 97.
https://www.genengnews.com/topics/omics/dna-and-the-unraveling-of-james-watson/
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Some consolidation in the single cell space - 10X Genomics (
@10xgenomics.bsky.social
) set to acquire Scale Biosciences
www.genengnews.com/topics/omics...
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10x Genomics Scales Up, Agrees to Acquire Scale Biosciences
An exclusive interview with Serge Saxonov of 10x Genomics and Giovanna Prout of Scale Biosciences on what the acquisition means for single cell genomics.
https://www.genengnews.com/topics/omics/10x-genomics-scales-up-agrees-to-acquire-scale-biosciences/
7 months ago
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reposted by
Shawn Baker
Element Biosciences
8 months ago
š¢ We are very proud to announce that over 50 of our
#AVITI24
5D
#multiomic
systems have already been installed around the globe enabling scientists to unravel the most complex questions about our biology.
bit.ly/458UCky
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Element Biosciences Surpasses 50 AVITI24⢠5D Multiomic System Installations In Just Months
Element Biosciences today announced that installations of its flagship AVITI24 5D Multiomic system have surpassed 50 units globally.
https://bit.ly/458UCky
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Atlas, Twist's DNA data storage spin-off, is claiming that "pretty quickly" the majority of DNA sequencing (by "orders of magnitude") will be for reading data storage. I'm skeptical. Maybe we have different definitions of "pretty quickly".
#dnasynth
#datastorage
www.genomeweb.com/business-new...
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Twist Spinoff Atlas Data Storage Designing Chip, Seeking Partner for Sequencing DNA-Based Archives
The California startup will have to convince companies across the economy to swap from rolls of magnetic tape to DNA as the vessel for their most important digital data.
https://www.genomeweb.com/business-news/twist-spinoff-atlas-data-storage-designing-chip-seeking-partner-sequencing-dna-based
9 months ago
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reposted by
Shawn Baker
Kristian G. Andersen
9 months ago
Quick update on this - a good one! Thanks to our fantastic colleagues at county HHSA, we're able to continue our wastewater surveillance work, including generating retroactive data from the last few months, as well as new data moving forward. For how long, we'll see, but expect updates soon! šā¤ļø
add a skeleton here at some point
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reposted by
Shawn Baker
Vincent J Lynch šš¦£š¦„ š¦šš¢š
9 months ago
Updated a broken link in my substack post about the
#ColossalBio
#DeExtinction
#DisInformation
campaign ā dire wolves are still extinct.
open.substack.com/pub/devoevom...
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The Extinction of Truth
Or, a Colossal Pile of Bullshit
https://open.substack.com/pub/devoevomed/p/the-extinction-of-truth?r=52j305&utm_campaign=post&utm_medium=web
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Illumina goes āall inā on proteomics by purchasing SomaLogic (from Standard BioTools). Can they overtake Olink?
www.illumina.com/company/news...
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Illumina to acquire SomaLogic, accelerating its proteomics business and advancing the company's multiomics strategy
https://www.illumina.com/company/news-center/press-releases/press-release-details.html?newsid=3214bfaf-0c8c-4c58-9784-a446caca285b
9 months ago
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Can't wait to listen to this one!
add a skeleton here at some point
9 months ago
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www.genengnews.com/topics/artif...
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Xaira Therapeutics Releases Largest Perturb-Seq Dataset to Power the Virtual Cell
The AI unicorn's Perturb-seq atlas is publicly available and detects dose-dependent genetic effects to enhance predictive power for drug discovery.
https://www.genengnews.com/topics/artificial-intelligence/xaira-therapeutics-releases-largest-perturb-seq-dataset-to-power-the-virtual-cell/
9 months ago
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The most charitable thing I can say about Twistās (
@twistbioscience.com
) China tariff request is that itās āunconvincingā. Tariffs arenāt the way to protect IP. This is just about making Chinese DNA more expensive.
endpoints.news/twist-biosci...
downloads.regulations.gov/BIS-2025-002...
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https://downloads.regulations.gov/BIS-2025-0022-0154/attachment_1.pdf
9 months ago
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@jaredwhitlock.bsky.social
has written an article about the many new companies spun out/spawned by ex-Illuminites. In it he references the crowdsourced "Illumina Diaspora" database Millard Chan and I created to keep track of them all.
sandiegomics.com/illumina-dia...
endpts.com/how-illumina...
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DNA giant Illumina spawned an ecosystem of competitors and customers
For Illumina, its former employees are both a boon and a problem. In the 27 years since its founding, the DNA sequencing company unlocked new frontiers in biology, medicine and ...
https://endpts.com/how-illuminas-ex-employees-became-its-customers-and-competitors/
10 months ago
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Roche has finally given their upcoming DNA sequencer a name - Axelios. So now we can stop calling it "Genia + Stratos".
www.genomeweb.com/molecular-di...
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Roche Highlights New Tests, Instrument Launches at Investor Day
The firm touted new assays, provided an update on its nanopore sequencer, and offered insights into upcoming pipeline launches.
https://www.genomeweb.com/molecular-diagnostics/roche-highlights-new-tests-instrument-launches-investor-day
10 months ago
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Illumina hasn't had a lot of wins recently. I think they'd count this as a win.
endpts.com/sec-expected...
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Exclusive: SEC expected to drop investigation of Illumina's $8B Grail deal
The SEC is expected to drop an investigation into Illumina's $8 billion acquisition of cancer test developer Grail, Endpoints News has learned.
https://endpts.com/sec-expected-to-drop-investigation-of-illuminas-8b-grail-deal/
10 months ago
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This has to be one of the most "anti-science" and "anti-common sense" administrations the US has ever had. Tariffs are a tax, pure and simple and the consumer will be the one to pay the cost.
add a skeleton here at some point
10 months ago
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@twistbioscience.com
is spinning out their DNA data storage tech. Atlas Data Storage is kicking off with $155M in "seed" funding š³ That's a lot of "seed" for a market that doesn't exist yet. Best of luck!
#dnasynthesis
investors.twistbioscience.com/news-release...
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https://investors.twistbioscience.com/news-releases/news-release-details/twist-bioscience-spins-out-dna-data-storage-independent-company
10 months ago
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Novartis announced a big commitment/addition to the San Diego biotech scene.
www.sandiegouniontribune.com/2025/04/10/a...
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Amid tariff turmoil, Swiss drugmaker commits to build $1.1B research hub in San Diego
Novartis plans to make San Diego the center of its West Coast research hub.
https://www.sandiegouniontribune.com/2025/04/10/amid-tariff-turmoil-novartis-commits-to-build-1-1b-research-hub-in-san-diego/?utm_email=755324E3D4E2B461745BE4555E&lctg=755324E3D4E2B461745BE4555E&active=yesD&utm_source=listrak&utm_medium=Email&utm_term=https%3a%2f%2fwww.sandiegouniontribune.com%2f2025%2f04%2f10%2famid-tariff-turmoil-novartis-commits-to-build-1-1b-research-hub-in-san-diego%2f&utm_campaign=sdut-san_diego_union_tribune-san_diego_north_county-nl&utm_content=automated
11 months ago
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Things just keep getting worse for ILMN. Stagnant growth, increased competition from
@elembio.bsky.social
and Ultima, the threat of competition from Roche SBX, and now theyāre shut down in China where they get 7% of their revenue. Yikes.
www.reuters.com/business/hea...
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China bans imports of Illumina's gene sequencers right after Trump tariff action
China announced a ban on Tuesday on imports of genetic sequencers from U.S. medical equipment maker Illumina , just minutes after U.S. President Donald Trump's additional 10% tariff on Chinese goods took effect.
https://www.reuters.com/business/healthcare-pharmaceuticals/china-bans-imports-illuminas-gene-sequencers-2025-03-04/
about 1 year ago
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reposted by
Shawn Baker
Eric Topol
about 1 year ago
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
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Wow, perhaps Tang Capital was just trying to buy Singular Genomics to shut them down for the cash. I assumed Tang was trying to combine them with other acquisitions. Glad they werenāt the winning bid.
add a skeleton here at some point
about 1 year ago
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reposted by
Shawn Baker
Randall Munroe
about 1 year ago
RNA
xkcd.com/3056
154
17845
2729
reposted by
Shawn Baker
Catharine.Aquino
about 1 year ago
Xenium product updates : RNA and protein multiomics workflow
@10xgenomics.bsky.social
#AGBT2025
#AGBT25
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reposted by
Shawn Baker
Catharine.Aquino
about 1 year ago
#visiumhd
product updates : segmentation , visium HD XL , visium hd 3ā
@10xgenomics.bsky.social
#agbt25
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Looking forward to seeing what 10X has in store for 2025
add a skeleton here at some point
about 1 year ago
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reposted by
Shawn Baker
Jared Whitlock
about 1 year ago
I am the features editor at Endpoints News. We're closely reporting on the Trump administration slashing the federal workforce and the impact on biomedical research. I want to hear your stories and tips. Signal at: @jaredwhitlock.73. I can honor requests for anonymity.
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reposted by
Shawn Baker
Jared Whitlock
about 1 year ago
Drug giant Roche has long had a bad reputation in DNA sequencing. But no longer, it appears. Latest here:
endpts.com/roche-no-lon...
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Roche no longer wants to be where āDNA sequencing goes to dieā
Has drug giant Roche finally cracked DNA sequencing? The company has claimed it can decode the genome in as little as four hours, potentially a major step forward for an industry thatās vital for diag...
https://endpts.com/roche-no-longer-wants-to-be-where-dna-sequencing-goes-to-die/
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Rocheās Fantasy Sequencer Slowly Turning Into a Fantastic Reality
#sequencing
#nanopore
#genomics
sandiegomics.com/roches-fanta...
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Rocheās Fantasy Sequencer Slowly Turning Into a Fantastic Reality
After 10+ years of mostly silence, Roche is finally starting to lift the curtain on their nanopore sequencer. Itās based on a combination of Geniaās nanopore platform (acquired in 2014) and Stratosā¦
https://sandiegomics.com/roches-fantasy-sequencer-slowly-turning-into-a-fantastic-reality/
about 1 year ago
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I'll post my Roche sequencer update soon (need to wait for the webinar to end), but let's see how ILMN is taking the news...
about 1 year ago
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Maybe a little too much credit to Element and Ultima, but otherwise an excellent story!
add a skeleton here at some point
about 1 year ago
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#AGBT
sounds like it's going to be a banger with lots of big announcements. The latest is Illumina announcing their upcoming high resolution, broad coverage, large surface area spatial transcriptomics platform. Set for launch in 2026.
www.genengnews.com/topics/omics...
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Illumina Unveils Spatial Technology Days Before AGBT Meeting
Illumina announces a new NGS-based spatial technology kit and new software platform, Illumina Connected Multiomics.
https://www.genengnews.com/topics/omics/illumina-unveils-spatial-technology-days-before-agbt-meeting/
about 1 year ago
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reposted by
Shawn Baker
about 1 year ago
Hi everyone on Bluesky working in
#genomics
#NGS
. Today is Valentines day. How many of you are more excited about Feb 20th?! Read my new post on Enseqlopedia Roche emerges from the Lazarus pit to take on Illumina
enseqlopedia.com/2025/02/roch...
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Roche emerges from the Lazarus pit
Is Roche going toĀ "knock it out of the park"Ā orĀ "jump the shark"? Everyone I know is excited, even if many of them are sceptical, about the Feb 20th webinar and what we will learn about SBX. Alex Dick...
http://enseqlopedia.com/2025/02/roche-emerges-from-the-lazarus-pit/
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A sneak peek at Rocheās nanopore sequencer. Really makes me wish I was going to
#AGBT
this year!
#genomics
#nanopore
#sequencing
sandiegomics.com/roche-has-en...
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Roche has entered the conversationā¦
Itās been an exciting couple of years for the sequencing market. Unless youāre a sequencing company, especially one named āIlluminaā, and then maybe itās been more terrifying. But for sequencing cuā¦
https://sandiegomics.com/roche-has-entered-the-conversation/
about 1 year ago
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reposted by
Shawn Baker
Mike Schatz
about 1 year ago
So long San Diego! Hereās my opinionated meeting report from
#PAG2025
|
#PAG32
. What else did I miss???
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reposted by
Shawn Baker
Ewan Birney
about 1 year ago
Some thoughts about what I am looking forward this year from my vantage point of computational molecular biology. One mega-trend for me; we will definitely see more AI methods of all sorts emerge.
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reposted by
Shawn Baker
Randall Munroe
about 1 year ago
What if we put a pool on the moon? Watch the latest What If? video collaboration with Minute Earth!
www.youtube.com/watch?v=aIIB...
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What if we put a pool on the moon?
YouTube video by xkcd's What If?
https://www.youtube.com/watch?v=aIIBBj6KR-Y
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Coastal Redwood fairy ring
over 1 year ago
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A gorgeous
#sandiego
#sunset
tonight!
over 1 year ago
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reposted by
Shawn Baker
Alexis Verger š§¬š§«š§Ŗ
over 1 year ago
Look who's here
@pnas.org
āļø
@science.org
āļø
@naturecellbiology.bsky.social
āļø
@natrevgenet.bsky.social
āļø
@naturebiotech.bsky.social
āļø
@naturemicrobiol.bsky.social
āļø
@naturechemistry.bsky.social
āļø
@genesdev.bsky.social
āļø
@cellchembiol.bsky.social
āļø
@genomeresearch.bsky.social
āļø
@jcellbiol.bsky.social
āļø
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reposted by
Shawn Baker
Keith Robison
over 1 year ago
www.nature.com/articles/s41...
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A functional microbiome catalogue crowdsourced from North American rivers - Nature
GROWdb defines US river microbiomes at the genome level.
https://www.nature.com/articles/s41586-024-08240-z
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reposted by
Shawn Baker
Matthew Freeman
over 1 year ago
Hereās my spreadsheet of starter packs (>80!) related to broadly āmechanistic biologyā plus some intriguing extras Complete with collective nouns Iāve been tracking these but now canāt keep up Hope itās helpful 2/2
docs.google.com/spreadsheets...
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@mjafreeman.bsky.social's BlueSky starter packs for 'mechanistic' biologists
https://docs.google.com/spreadsheets/d/1r74eYlX9CxrauOjPWUwYrzVfQGkeKs5HsxxQCqlaceY/edit?gid=0#gid=0
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reposted by
Shawn Baker
Jonathan Jacobs
over 1 year ago
During lunch I starting moving my lists over from Twitter to Blue - first one is done: "Genomics Biz" list. It's much smaller here vs. on Twitter as many companies - including ILMN and ONT - don't have a presence on Blue.
@pacbio.bsky.social
does though! š Bsky list here:
bsky.app/profile/did:...
add a skeleton here at some point
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PacBioās Vega system - the new (small) thing in long reads
sandiegomics.com/pacbios-vega...
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PacBioās Vega system ā the new (small) thing in long reads
PacBio has announced their anticipated desktop HiFi sequencer, the Vega sequencing platform, something theyāve been talking about since early 2023. The platform, which is slated to ship in Q1 2025,ā¦
https://sandiegomics.com/pacbios-vega-system-the-new-small-thing-in-long-reads/
over 1 year ago
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PacBioās new SPRQ chemistry brings down the LR human genome to $500. Is it enough to move the needle (faster)?
sandiegomics.com/pacbio-sprq/
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PacBio Brings Down Long Read Human Genome to $500
PacBio announced their new SPRQ long read sequencing chemistry ahead of ASHG. While it improves a couple of things, the headline is that it brings down the cost of a long read HiFi human genome to ā¦
https://sandiegomics.com/pacbio-sprq/
over 1 year ago
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After another year of fresh competition in the DNA sequencing space, thereās a clear loser and clear winner. Surprise twist: itās the same company!
sandiegomics.com/2023-sequenc...
#genomics
#sequencing
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2023 Sequencing Market Share ā The Tide is Turning⦠Very Slowly
Itās an exciting time in the sequencing industry. After years of dominance, Illumina started facing competition on all fronts in 2022. Element Biosciences and Singular Genomics launched their desktā¦
https://sandiegomics.com/2023-sequencing-market-share-the-tide-is-turning-very-slowly/
over 1 year ago
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reposted by
Shawn Baker
Keith Robison
almost 2 years ago
omicsomics.blogspot.com/2024/04/a-pe...
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A Peek At QuantumSI's Protein Sequencer
A number of academic labs and startups have been trying to build new ways of parallel sequencing of large numbers of peptides using schemes ...
http://omicsomics.blogspot.com/2024/04/a-peek-at-quantumsis-protein-sequencer.html?m=1
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