Shawn Baker
@sandiegomics.bsky.social
📤 850
📥 185
📝 87
Genomics consultant/advisor/investor
https://sandiegomics.com
Some consolidation in the single cell space - 10X Genomics (
@10xgenomics.bsky.social
) set to acquire Scale Biosciences
www.genengnews.com/topics/omics...
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10x Genomics Scales Up, Agrees to Acquire Scale Biosciences
An exclusive interview with Serge Saxonov of 10x Genomics and Giovanna Prout of Scale Biosciences on what the acquisition means for single cell genomics.
https://www.genengnews.com/topics/omics/10x-genomics-scales-up-agrees-to-acquire-scale-biosciences/
2 months ago
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Element Biosciences
2 months ago
📢 We are very proud to announce that over 50 of our
#AVITI24
5D
#multiomic
systems have already been installed around the globe enabling scientists to unravel the most complex questions about our biology.
bit.ly/458UCky
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Element Biosciences Surpasses 50 AVITI24™ 5D Multiomic System Installations In Just Months
Element Biosciences today announced that installations of its flagship AVITI24 5D Multiomic system have surpassed 50 units globally.
https://bit.ly/458UCky
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Atlas, Twist's DNA data storage spin-off, is claiming that "pretty quickly" the majority of DNA sequencing (by "orders of magnitude") will be for reading data storage. I'm skeptical. Maybe we have different definitions of "pretty quickly".
#dnasynth
#datastorage
www.genomeweb.com/business-new...
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Twist Spinoff Atlas Data Storage Designing Chip, Seeking Partner for Sequencing DNA-Based Archives
The California startup will have to convince companies across the economy to swap from rolls of magnetic tape to DNA as the vessel for their most important digital data.
https://www.genomeweb.com/business-news/twist-spinoff-atlas-data-storage-designing-chip-seeking-partner-sequencing-dna-based
3 months ago
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Shawn Baker
Kristian G. Andersen
3 months ago
Quick update on this - a good one! Thanks to our fantastic colleagues at county HHSA, we're able to continue our wastewater surveillance work, including generating retroactive data from the last few months, as well as new data moving forward. For how long, we'll see, but expect updates soon! 🌟❤️
add a skeleton here at some point
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Shawn Baker
Vincent J Lynch 🐘🦣🦥 🦇🐋🐢🐍
4 months ago
Updated a broken link in my substack post about the
#ColossalBio
#DeExtinction
#DisInformation
campaign – dire wolves are still extinct.
open.substack.com/pub/devoevom...
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The Extinction of Truth
Or, a Colossal Pile of Bullshit
https://open.substack.com/pub/devoevomed/p/the-extinction-of-truth?r=52j305&utm_campaign=post&utm_medium=web
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Illumina goes “all in” on proteomics by purchasing SomaLogic (from Standard BioTools). Can they overtake Olink?
www.illumina.com/company/news...
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Illumina to acquire SomaLogic, accelerating its proteomics business and advancing the company's multiomics strategy
https://www.illumina.com/company/news-center/press-releases/press-release-details.html?newsid=3214bfaf-0c8c-4c58-9784-a446caca285b
4 months ago
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Can't wait to listen to this one!
add a skeleton here at some point
4 months ago
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www.genengnews.com/topics/artif...
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Xaira Therapeutics Releases Largest Perturb-Seq Dataset to Power the Virtual Cell
The AI unicorn's Perturb-seq atlas is publicly available and detects dose-dependent genetic effects to enhance predictive power for drug discovery.
https://www.genengnews.com/topics/artificial-intelligence/xaira-therapeutics-releases-largest-perturb-seq-dataset-to-power-the-virtual-cell/
4 months ago
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The most charitable thing I can say about Twist’s (
@twistbioscience.com
) China tariff request is that it’s “unconvincing”. Tariffs aren’t the way to protect IP. This is just about making Chinese DNA more expensive.
endpoints.news/twist-biosci...
downloads.regulations.gov/BIS-2025-002...
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https://downloads.regulations.gov/BIS-2025-0022-0154/attachment_1.pdf
4 months ago
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@jaredwhitlock.bsky.social
has written an article about the many new companies spun out/spawned by ex-Illuminites. In it he references the crowdsourced "Illumina Diaspora" database Millard Chan and I created to keep track of them all.
sandiegomics.com/illumina-dia...
endpts.com/how-illumina...
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DNA giant Illumina spawned an ecosystem of competitors and customers
For Illumina, its former employees are both a boon and a problem. In the 27 years since its founding, the DNA sequencing company unlocked new frontiers in biology, medicine and ...
https://endpts.com/how-illuminas-ex-employees-became-its-customers-and-competitors/
4 months ago
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Roche has finally given their upcoming DNA sequencer a name - Axelios. So now we can stop calling it "Genia + Stratos".
www.genomeweb.com/molecular-di...
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Roche Highlights New Tests, Instrument Launches at Investor Day
The firm touted new assays, provided an update on its nanopore sequencer, and offered insights into upcoming pipeline launches.
https://www.genomeweb.com/molecular-diagnostics/roche-highlights-new-tests-instrument-launches-investor-day
4 months ago
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Illumina hasn't had a lot of wins recently. I think they'd count this as a win.
endpts.com/sec-expected...
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Exclusive: SEC expected to drop investigation of Illumina's $8B Grail deal
The SEC is expected to drop an investigation into Illumina's $8 billion acquisition of cancer test developer Grail, Endpoints News has learned.
https://endpts.com/sec-expected-to-drop-investigation-of-illuminas-8b-grail-deal/
5 months ago
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This has to be one of the most "anti-science" and "anti-common sense" administrations the US has ever had. Tariffs are a tax, pure and simple and the consumer will be the one to pay the cost.
add a skeleton here at some point
5 months ago
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@twistbioscience.com
is spinning out their DNA data storage tech. Atlas Data Storage is kicking off with $155M in "seed" funding 😳 That's a lot of "seed" for a market that doesn't exist yet. Best of luck!
#dnasynthesis
investors.twistbioscience.com/news-release...
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https://investors.twistbioscience.com/news-releases/news-release-details/twist-bioscience-spins-out-dna-data-storage-independent-company
5 months ago
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Novartis announced a big commitment/addition to the San Diego biotech scene.
www.sandiegouniontribune.com/2025/04/10/a...
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Amid tariff turmoil, Swiss drugmaker commits to build $1.1B research hub in San Diego
Novartis plans to make San Diego the center of its West Coast research hub.
https://www.sandiegouniontribune.com/2025/04/10/amid-tariff-turmoil-novartis-commits-to-build-1-1b-research-hub-in-san-diego/?utm_email=755324E3D4E2B461745BE4555E&lctg=755324E3D4E2B461745BE4555E&active=yesD&utm_source=listrak&utm_medium=Email&utm_term=https%3a%2f%2fwww.sandiegouniontribune.com%2f2025%2f04%2f10%2famid-tariff-turmoil-novartis-commits-to-build-1-1b-research-hub-in-san-diego%2f&utm_campaign=sdut-san_diego_union_tribune-san_diego_north_county-nl&utm_content=automated
6 months ago
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Things just keep getting worse for ILMN. Stagnant growth, increased competition from
@elembio.bsky.social
and Ultima, the threat of competition from Roche SBX, and now they’re shut down in China where they get 7% of their revenue. Yikes.
www.reuters.com/business/hea...
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China bans imports of Illumina's gene sequencers right after Trump tariff action
China announced a ban on Tuesday on imports of genetic sequencers from U.S. medical equipment maker Illumina , just minutes after U.S. President Donald Trump's additional 10% tariff on Chinese goods took effect.
https://www.reuters.com/business/healthcare-pharmaceuticals/china-bans-imports-illuminas-gene-sequencers-2025-03-04/
7 months ago
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reposted by
Shawn Baker
Eric Topol
7 months ago
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
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Wow, perhaps Tang Capital was just trying to buy Singular Genomics to shut them down for the cash. I assumed Tang was trying to combine them with other acquisitions. Glad they weren’t the winning bid.
add a skeleton here at some point
7 months ago
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reposted by
Shawn Baker
Randall Munroe
7 months ago
RNA
xkcd.com/3056
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Shawn Baker
Catharine.Aquino
8 months ago
Xenium product updates : RNA and protein multiomics workflow
@10xgenomics.bsky.social
#AGBT2025
#AGBT25
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Shawn Baker
Catharine.Aquino
8 months ago
#visiumhd
product updates : segmentation , visium HD XL , visium hd 3’
@10xgenomics.bsky.social
#agbt25
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Looking forward to seeing what 10X has in store for 2025
add a skeleton here at some point
8 months ago
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reposted by
Shawn Baker
Jared Whitlock
8 months ago
I am the features editor at Endpoints News. We're closely reporting on the Trump administration slashing the federal workforce and the impact on biomedical research. I want to hear your stories and tips. Signal at: @jaredwhitlock.73. I can honor requests for anonymity.
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reposted by
Shawn Baker
Jared Whitlock
8 months ago
Drug giant Roche has long had a bad reputation in DNA sequencing. But no longer, it appears. Latest here:
endpts.com/roche-no-lon...
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Roche no longer wants to be where ‘DNA sequencing goes to die’
Has drug giant Roche finally cracked DNA sequencing? The company has claimed it can decode the genome in as little as four hours, potentially a major step forward for an industry that’s vital for diag...
https://endpts.com/roche-no-longer-wants-to-be-where-dna-sequencing-goes-to-die/
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Roche’s Fantasy Sequencer Slowly Turning Into a Fantastic Reality
#sequencing
#nanopore
#genomics
sandiegomics.com/roches-fanta...
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Roche’s Fantasy Sequencer Slowly Turning Into a Fantastic Reality
After 10+ years of mostly silence, Roche is finally starting to lift the curtain on their nanopore sequencer. It’s based on a combination of Genia’s nanopore platform (acquired in 2014) and Stratos…
https://sandiegomics.com/roches-fantasy-sequencer-slowly-turning-into-a-fantastic-reality/
8 months ago
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I'll post my Roche sequencer update soon (need to wait for the webinar to end), but let's see how ILMN is taking the news...
8 months ago
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Maybe a little too much credit to Element and Ultima, but otherwise an excellent story!
add a skeleton here at some point
8 months ago
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#AGBT
sounds like it's going to be a banger with lots of big announcements. The latest is Illumina announcing their upcoming high resolution, broad coverage, large surface area spatial transcriptomics platform. Set for launch in 2026.
www.genengnews.com/topics/omics...
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Illumina Unveils Spatial Technology Days Before AGBT Meeting
Illumina announces a new NGS-based spatial technology kit and new software platform, Illumina Connected Multiomics.
https://www.genengnews.com/topics/omics/illumina-unveils-spatial-technology-days-before-agbt-meeting/
8 months ago
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reposted by
Shawn Baker
8 months ago
Hi everyone on Bluesky working in
#genomics
#NGS
. Today is Valentines day. How many of you are more excited about Feb 20th?! Read my new post on Enseqlopedia Roche emerges from the Lazarus pit to take on Illumina
enseqlopedia.com/2025/02/roch...
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Roche emerges from the Lazarus pit
Is Roche going to "knock it out of the park" or "jump the shark"? Everyone I know is excited, even if many of them are sceptical, about the Feb 20th webinar and what we will learn about SBX. Alex Dick...
http://enseqlopedia.com/2025/02/roche-emerges-from-the-lazarus-pit/
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A sneak peek at Roche’s nanopore sequencer. Really makes me wish I was going to
#AGBT
this year!
#genomics
#nanopore
#sequencing
sandiegomics.com/roche-has-en...
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Roche has entered the conversation…
It’s been an exciting couple of years for the sequencing market. Unless you’re a sequencing company, especially one named “Illumina”, and then maybe it’s been more terrifying. But for sequencing cu…
https://sandiegomics.com/roche-has-entered-the-conversation/
8 months ago
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reposted by
Shawn Baker
Mike Schatz
9 months ago
So long San Diego! Here’s my opinionated meeting report from
#PAG2025
|
#PAG32
. What else did I miss???
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reposted by
Shawn Baker
Ewan Birney
9 months ago
Some thoughts about what I am looking forward this year from my vantage point of computational molecular biology. One mega-trend for me; we will definitely see more AI methods of all sorts emerge.
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reposted by
Shawn Baker
Randall Munroe
10 months ago
What if we put a pool on the moon? Watch the latest What If? video collaboration with Minute Earth!
www.youtube.com/watch?v=aIIB...
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What if we put a pool on the moon?
YouTube video by xkcd's What If?
https://www.youtube.com/watch?v=aIIBBj6KR-Y
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Coastal Redwood fairy ring
10 months ago
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A gorgeous
#sandiego
#sunset
tonight!
10 months ago
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reposted by
Shawn Baker
Alexis Verger 🧬🧫🧪
11 months ago
Look who's here
@pnas.org
✔️
@science.org
✔️
@naturecellbiology.bsky.social
✔️
@natrevgenet.bsky.social
✔️
@naturebiotech.bsky.social
✔️
@naturemicrobiol.bsky.social
✔️
@naturechemistry.bsky.social
✔️
@genesdev.bsky.social
✔️
@cellchembiol.bsky.social
✔️
@genomeresearch.bsky.social
✔️
@jcellbiol.bsky.social
✔️
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Shawn Baker
Keith Robison
11 months ago
www.nature.com/articles/s41...
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A functional microbiome catalogue crowdsourced from North American rivers - Nature
GROWdb defines US river microbiomes at the genome level.
https://www.nature.com/articles/s41586-024-08240-z
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reposted by
Shawn Baker
Matthew Freeman
11 months ago
Here’s my spreadsheet of starter packs (>80!) related to broadly ‘mechanistic biology’ plus some intriguing extras Complete with collective nouns I’ve been tracking these but now can’t keep up Hope it’s helpful 2/2
docs.google.com/spreadsheets...
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@mjafreeman.bsky.social's BlueSky starter packs for 'mechanistic' biologists
https://docs.google.com/spreadsheets/d/1r74eYlX9CxrauOjPWUwYrzVfQGkeKs5HsxxQCqlaceY/edit?gid=0#gid=0
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Shawn Baker
Jonathan Jacobs
11 months ago
During lunch I starting moving my lists over from Twitter to Blue - first one is done: "Genomics Biz" list. It's much smaller here vs. on Twitter as many companies - including ILMN and ONT - don't have a presence on Blue.
@pacbio.bsky.social
does though! 🙌 Bsky list here:
bsky.app/profile/did:...
add a skeleton here at some point
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PacBio’s Vega system - the new (small) thing in long reads
sandiegomics.com/pacbios-vega...
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PacBio’s Vega system – the new (small) thing in long reads
PacBio has announced their anticipated desktop HiFi sequencer, the Vega sequencing platform, something they’ve been talking about since early 2023. The platform, which is slated to ship in Q1 2025,…
https://sandiegomics.com/pacbios-vega-system-the-new-small-thing-in-long-reads/
11 months ago
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PacBio’s new SPRQ chemistry brings down the LR human genome to $500. Is it enough to move the needle (faster)?
sandiegomics.com/pacbio-sprq/
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PacBio Brings Down Long Read Human Genome to $500
PacBio announced their new SPRQ long read sequencing chemistry ahead of ASHG. While it improves a couple of things, the headline is that it brings down the cost of a long read HiFi human genome to …
https://sandiegomics.com/pacbio-sprq/
11 months ago
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After another year of fresh competition in the DNA sequencing space, there’s a clear loser and clear winner. Surprise twist: it’s the same company!
sandiegomics.com/2023-sequenc...
#genomics
#sequencing
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2023 Sequencing Market Share – The Tide is Turning… Very Slowly
It’s an exciting time in the sequencing industry. After years of dominance, Illumina started facing competition on all fronts in 2022. Element Biosciences and Singular Genomics launched their deskt…
https://sandiegomics.com/2023-sequencing-market-share-the-tide-is-turning-very-slowly/
over 1 year ago
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reposted by
Shawn Baker
Keith Robison
over 1 year ago
omicsomics.blogspot.com/2024/04/a-pe...
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A Peek At QuantumSI's Protein Sequencer
A number of academic labs and startups have been trying to build new ways of parallel sequencing of large numbers of peptides using schemes ...
http://omicsomics.blogspot.com/2024/04/a-peek-at-quantumsis-protein-sequencer.html?m=1
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reposted by
Shawn Baker
Keith Robison
over 1 year ago
Bruker Wins Nanostring Auction
omicsomics.blogspot.com/2024/04/bruk...
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The 2024 eclipse did not disappoint! Special shout out to the residents of Francisco I Madero, Mexico for being so warm and inviting.
over 1 year ago
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reposted by
Shawn Baker
Keith Robison
over 1 year ago
We are actively recruiting for two open Computational Biology positions in our NGS group - both covered by this listing
www.ginkgobioworks.com/job-listings...
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Shawn Baker
Keith Robison
over 1 year ago
Post-AGBT: Element AVITI Sequencing Updates
omicsomics.blogspot.com/2024/02/post...
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Post-AGBT: Element AVITI Sequencing Updates
Element has been very busy over the past year and in the Silver Sponsor presentation covered updates since last AGBT as well as a number of ...
http://omicsomics.blogspot.com/2024/02/post-agbt-element-aviti-sequencing.html?m=1
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reposted by
Shawn Baker
Keith Robison
over 1 year ago
Post-AGBT: Both Element & Singular Want Spatial to Go With The Flow(cells)
omicsomics.blogspot.com/2024/02/post...
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Post-AGBT: Both Element & Singular Want Spatial to Go With The Flow(cells)
Element Biosciences and Singular Genomics have often appeared to be on roughly parallel trajectories, though with key differences. Both com...
http://omicsomics.blogspot.com/2024/02/post-agbt-both-element-singular-want.html?m=1
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reposted by
Shawn Baker
Keith Robison
over 1 year ago
AGBT Follow-up: Ultima Genomics UG100, Volta Labs Calypson, N6Tec iconPCR
#AGBT
#AGBT24
omicsomics.blogspot.com/2024/02/agbt...
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AGBT Follow-up: Ultima Genomics UG100, Volta Labs Calypson, N6Tec iconPCR
A confusion of ideas for AGBT follow-up have collided with the inevitable post-AGBT return-to-ordinary-life requirements. To try to avoid a...
http://omicsomics.blogspot.com/2024/02/agbt-follow-up-ultima-genomics-ug100.html
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reposted by
Shawn Baker
Adam Phillippy
over 1 year ago
We are looking for a new director of the NIH Intramural Sequencing Center! Please spread the word:
www.genome.gov/careers-trai...
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Director, NIH Intramural Sequencing Center
NHGRI seeks to identify an outstanding Director to lead its NIH Intramural Sequencing Center (NISC) within its Division of Intramural Research (DIR).
https://www.genome.gov/careers-training/NHGRI-Jobs/Director-NISC
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