Full house @10xgenomics.bsky.social user day! People didn’t come because of the bagels ( as there are still some left) but for technology 😂 @fgcz-en.bsky.social

🧬 Meet our #Genomics Unit! Led by @catharineaquino.bsky.social, our team specializes in #ngs, #single-cell transcriptomics, #spatial gene expression, #long-read sequencing & genome engineering. From DNA to RNA to protein to metabolites! Video 🔗 learn more about our services: tinyurl.com/zemh8bsy

Big thanks to Monica Manotas for visiting the @fgcz-en.bsky.social in your very first week as CEO of Tecan. Nothing like jumping straight into customer visits (starting with the nicest customer, of course 😇 ) and what a fantastic way to kick off the new role!

🔬Ever wondered what goes on inside one of Switzerland's leading #omics core facilities? Join us for an exclusive behind-the-scenes tour of the Functional Genomics Center Zurich! Supporting researchers from @ethz.ch, UZH, and beyond across #genomics, #proteomics & #metabolomics. 🔗 fgcz.ch

Hmm, was it really in a lower level before? 🫣

Massive thanks to the dream team behind the Genomics Unit, both on screen and behind the scenes. From next-gen sequencing to spatial transcriptomics to CRISPR, we’ve got you covered with cutting-edge, state-of-the-art genomics technologies. shorturl.at/H4Oa2

Swiss Genome of the 1918 Influenza Virus Reconstructed! So proud of @fgcz-en.bsky.social Genomics Unit’s Spatial Expert,Christian Urban,for authoring such a cool paper!Nothing like cool science+great storytelling! Of course,part of the sequencing was done at the FGCZ www.news.uzh.ch/en/articles/...

Take a peek inside our @fgcz-en.bsky.social . Watching the video, I’m struck by how neat, clean, and sci-fi labglam it is. I can confirm it really does look like that IRL. We didn’t tidy up just for the video and we really wear lab coats 😄 oc-aem-dist-downloads.ethz.ch/mh_default_o...

A Promising Single Cell Alternative Before we roll out any new service, internal benchmarking is a must. This time we tested Illumina’s Single Cell 3' RNA prep kit (which I will call PIPseq) against the reigning champ, 10x Genomics GEMX 3' Gene Expression kit (GEMX for short). What we found:

Great to have Duncan Yu of MGI swing by the @fgcz-en.bsky.social ! It’s always a pleasure when genomics powerhouses come bearing insights. Of course , we did the required photo op in front of our building artwork 😆 😀

If you're at #ASMS2025, check out the posters from our @fgcz-en.bsky.social #Proteomics colleagues, especially the one on NGS-based proteomics that the #Genomics and #Bioinformatics units had the pleasure of contributing to 😊. @paolonanni.bsky.social TobiasKockmann @hubertr.bsky.social ClaudiaFortes

The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers. #RNAseq #PCRduplication #Benchmarking #Genomics #GenomeBiology genomebiology.biomedcentral.com/articles/10....

🧬 New study in Gen. Bio.! We tested how RNA input & PCR cycles affect duplication rates across 4 sequencers. ↘️ RNA = ↗️ duplicates = ↘️ diversity. Key for optimizing RNA-seq protocols! Thanks + congrats to @catharineaquino.bsky.social @nataliazajac.bsky.social + collaborators! 🔗 tinyurl.com/bdcuen59

I’m very happy to share our latest ABRF - Genomics ResearchGroup study “The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers,” is now published in Genome Biology! genomebiology.biomedcentral.com/articles/10....

The yearly Core4Life Genomics meeting is my favorite of the year. 8 great EU cores meet to swap secrets, voodoos & hacks on running genomics tech. This year was hosted by Vladimir Benes and Laura Villacorta @EMBL. The vibe: a platform-agnostic space where tech diversity isn’t a bug , it’s a feature.

🧬 FGCZ 10X Genomics Workshop Single-cell analysis on the 10x Cloud Analysis platform: from CellRanger to Loupe to community tools! Discuss with 10x Applied Bioinformatics team + FGCZ bioinformaticians. 📆June 12, 9:00-15:30 📍UZH Irchel Y59-G30 Limited spots—register now! tinyurl.com/4wb3rxj5

Looking at cheese microbiome using @pacbio.bsky.social sequencing #PRISM by Todd Treangen

Jonas Korlach recapping the history of @pacbio.bsky.social at Boston PRiSM #25 years . Fantastic talk as usual from him.

Jonas Korlach recapping the history of @pacbio.bsky.social at Boston PRiSM #25 years . Fantastic talk as usual from him.

10X Genomics @10xgenomics.bsky.social $TXG Stock up circa 15% after Q1 results.

Pretty radical to see some of the R&D updates in the pipeline at @PacBio #PacBioPRISM Increases in chip size from 200–> 300mm, density and improvements in chemistry at PB leading to increased Yield and Hifi conversion.

I would argue that we are still in the next generation sequencing era. Yes, there was a lot of improvements but mostly in throughput. No big leap yet that changes fundamentally how we think (or discuss projects).

I’m really stoked to join "Beyond Genomics: A Conversation with Thought Leaders on NGS-Based Proteomics" @GenomeWeb to talk NGSbased proteomics from decoding astronauts'molecularstress signals (Christopher Mason ), to mining UKBiobank proteomes (John Overton ), to integrating it with NGS workflows

Efficient near telomere-to-telomere assembly of Nanopore Simplex reads from @lh3lh3.bsky.social lab www.biorxiv.org/content/10.1...

I made a feed for all things Omics! Have your posts included in it by adding a 🧬plus any additional omics related emoji🧪🧫🔬🖥️💉🦠🥼. Anything Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, or Metagenomics related (or adjacent!) is welcome! bsky.app/profile/h2so...

Stellaromics Dives into the Thick of Spatial Genomics omicsomics.blogspot.com/2025/04/stella… 🧬🖥️

I’m crazy because I find it super fascinating that they went to space and back and their hair still looks perfect. Meanwhile, I walk to my kitchen and look like I fought a wind tunnel.

Catharine Aquino, not on bluesky? On @10xgenomics.bsky.social update at EMEA users group meeting.

Our turn onstage #10XEMEAugm ! Core facilities and @10xgenomics.bsky.social can working together happily together.

I’m really enjoying the #10xEMEAugm . It’s clear that the attendees have single cell and spatial in their minds and came here to talk about it. European researchers are less distracted by world events.

Maria Greco is making me jealous of how they automated @10xgenomics.bsky.social protocols #10xEMEAugm

I got all the pins because we have all the @10xgenomics.bsky.social instruments #10xEMEAugm

EMEA core single cell superheroes panel discussion #10xEMEAugm

Jerome Nicod presenting on how they achieved huge savings with @10xgenomics.bsky.social Flex #10xEMEAugm

Niels from VIB presenting how to set up a single cell portfolio in a core facility #10xEMEAugm

Full house! I really miss Europe- wide user meetings. I made a lot of friends at the user meetings Illumina used to do . The only comment I have about the #10xEMEAugm is there should be an evening program because so we have time to talk to each other.

Yey! HD 3’ will work on cytassist and will not require tissue optimization! Good news! #10xEMEAugm

Happening now: 10X user meeting in Paris #10xEMEAugm Michael Schnall Levin starts by presenting their roadmap

Got to see under the skin of the MiSeq i100. Amazing technology lies within. Also checked out the Illumina Protein Prep setup while it was running.

I made a complete and comprehensive starter pack for computational biology: Follow @lh3lh3.bsky.social.

Proteoforms: This is where things start to get complicated. 🧬 🧪

Transcriptomics in the era of long-read sequencing. #RNAseq #LongReads #Bioinformatics @naturerevgenet.bsky.social 🧬🖥️ www.nature.com/articles/s41...

There I go, ruining the fun again! It’s not my fault—realism and pragmatism are part of the package when you’re turning Swiss.

Much needed session about Navigating the spatial technologies currently available #abrf2025. So many spatial tech now, which one to use when? @ioavlachos.bsky.social

I have 1 lighting talk at 12:30 and the GRG session today at 16:00 #abrf2025 and I didn’t sleep a minute due to jetlag. Yesterday, I had only 2 hours of sleep. Wish me luck.

Just sat through 2 user meetings #abrf2025 . Both need a bit of improvement ✌️I’m already exhausted and the meeting hasn’t started yet.

Direct in-sample sequencing on the Aviti soon. @elembio.bsky.social that’s Cool! #abrf2025

Pre-#ABRF2025 started! Molly He kicks off the first @elembio.bsky.social user meeting .

It’s frustrating—cruel—when conference hotel rooms don’t have a coffee maker or kettle, especially when you’re battling jet lag. #abrf2025