📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.

$44/gene enzymatic function test with just $799 assay configuration!!! ~$5K & we will boot your assay & run full 96 well plate experiment! How many enzymatic reactions does this entice you to deorphan?

When you go up to the Sierra Nevada to do the last seasonal snowpack depth measurement and there isn't any snow. #climate #climatechange #water

A Wish For Snail-Inspired Tulips My latest post: can a childhood fright inspire floral beauty? Also some name-dropping of my favorite leading edge floral genetic engineers omicsomics.blogspot.com/2026/03/a-wi...

Less than two weeks until #AGBTAg26 ! Looking forward to planting @Ginkgo flag there - may many productive discussions bloom around autonomous laboratories and cloud lab services!

icon16: Precise Amplification for All! 🧬🖥️ omicsomics.blogspot.com/2026/03/icon...

a lot depends on the complexity of the flow cell algebra but if it truly makes service lab workflows fast fast that is worth a lot. just makes planning easier.

They had one a long time ago. About 15 years or so ago I played around with something in R to pull down data via API. It was half baked even then, guess they decided ti unbake it altogether

will I be able to run 5000 low pass libraries on it faster than on a nova? what about amplicons?

2. I don't mind if people don't want to use Rust but instead of rewriting it from scratch every single time, why don't you write bindings and make them available for everyone? This is both easier and more maintainable, and would actually be helpful for the community.

Who’s Going To But Roche Axelios? 🖥️🧬 omicsomics.blogspot.com/2026/03/whos...

LinkedIn Laments 1 of N: Where's the API? omicsomics.blogspot.com/2026/03/link...

GitHub will be allowing Copilot to use your code for training its models, unless you opt out. Seems like the sort of thing some people might want to opt out of…

Same evidence can mean different things at different times. In 1644 Sir Kenelm Digby tells of a woman in Algiers with two thumbs on one hand. All her female ancestors and descendants had the same condition, but not her sons. He draws no conclusion about heredity. A century later, Maupertuis would.

Host read removal sounds simple. It's not. 🧫 Ep. 151 of #microbinfie: we talk with @bede.im about Deacon — why alignment-based approaches fall short, the sensitivity/specificity tradeoff, and what it takes to remove host reads at scale. Part 1 of 2. #metagenomics on.soundcloud.com/gEm7QyaTauvd...

What's the current best strategy to sequence complete transcripts in the ~20kb range? Should we attempt generating full length cDNA, or go for direct RNA on ONT? I suppose it will be a challenge in any case..

Dogs were widely distributed across western Eurasia during the Palaeolithic 🧬🖥️ www.nature.com/articles/s41...

Genomic history of early dogs in Europe 🖥️🧬 www.nature.com/articles/s41...

Market research question If you were building a course where each student gets to create their own GFP designs How many designs per student would be minimum to be interesting? What is ceiling on per student cost for experimental validation?

ElysION Fields omicsomics.blogspot.com/2026/03/elys... 🧬🖥️

Another week, another protocol added to Ginkgo Cloud Lab menu Strep tag purification w A280 quant Last week it was HiBiT quant Stay tuned for next week’s release cloud.ginkgo.bio

Excited to share my PhD work! The question: How is genome organization established? Here, we developed a low-input Micro-C method, Pico-C, and used it to map chromatin architecture across early stages of fly development. Here’s a quick Blue-torial 🙂 (1/n) www.nature.com/articles/s41...

Frogfish vid by Natalie Bondarenko.

How Genomics-saturated is Boston? We put Circos plots on our trains!

This is so cool: www.biorxiv.org/content/10.6... Discovery of a Genetic Toxin-Antidote System in Vertebrates hat tip to @asaflevylab.bsky.social

Roche Axelios1 Run Pricing: Not A Knockout - Yet? #AGBTGM26 🧬💻 omicsomics.blogspot.com/2026/03/roch...

Ginkgo Cloud Labs aims to democratize protein design validation No lab skills required! Use our EstiMate chatbot to explore protocols not yet supported. Please contact me to inquire about early access to unreleased protocols cloud.ginkgo.bio/protocols

We found a viral Trojan Horse: a virus can hide inside another virus.This one surprised us: deltaviruses don’t just borrow a helper virus. They can travel inside it. A literal Trojan Horse “virus-in-a-virus” route into cells. 🤯 Kudos to 1st author @viroscope.bsky.social and co-authors !

Complete Genomics Sale: Gruyère or Emmental? 🧬🖥️🧀 #AGBTGM26 omicsomics.blogspot.com/2026/03/comp...

Ultima Genomics Solaris 2.0: Greater Version, Smaller Beads, Lose A Box 🧬💻 #AGBTGM26 omicsomics.blogspot.com/2026/03/ulti...

Element Previews High-Throughput VITARI #AGBTGM26 🧬🖥️ omicsomics.blogspot.com?m=1

Ooof - I was sloppy on the Illumina TruPath Genome piece - easy to blame AGBT fatigue but that's a lazy excuse. The following errors have been corrected omicsomics.blogspot.com/2026/02/illu... 1. TruPath doesn't have an "e" in it. About 14 mistakes = including the title!

Illumina Constellation Becomes TruePath Genome #AGBTGM26 🧬🖥️ omicsomics.blogspot.com/2026/02/illu...

Canal Biosciences: Ligation Libraries without Distortions from End Repair 🧬🖥️ #AGBTGM26 omicsomics.blogspot.com/2026/02/cana...

Wish: Scientific Poster Snap Organizer App #AGBTGM26 omicsomics.blogspot.com/2026/02/wish...

Looking to find me at #AGBTGM26? Or dodge me? Look for Youdee the chicken, mascot of the University of Delaware

AI Agent -Driven Biochemical Optimization 🧬🖥️ omicsomics.blogspot.com/2026/02/ai-a...

academic.oup.com/genetics/adv... #histbio #hps

AGBT 2026 Preview #AGBT26 #AGBT2026 #AGBTGM26 🧬🖥️ omicsomics.blogspot.com/2026/02/agbt...

Saying there's no singular anti-vaccine movement is like saying there are no democrats or republicans. Sure, everyone has a unique viewpoint, but there is an organized and well-funded outfit furthering a specific set of priorities. RFK Jr's $497,000 salary came from somewhere.

Drug-Target Interaction Prediction with PIGLET https://www.biorxiv.org/content/10.64898/2026.02.18.706530v1

Cancer Driver Gene Discovery: A Patient-Level Statistical Framework https://www.biorxiv.org/content/10.64898/2026.02.16.706129v1

PRIZM: Combining Low-N Data and Zero-shot Models to Design Enhanced Protein Variants https://www.biorxiv.org/content/10.64898/2026.02.08.704628v1

Its still so baffling that in the age of Ai and wide access to information, more people are not interested in amateur biology. I'm not even talking bioengineering. Tissue culture, breeding, microbial prospecting, biochemistry, etc. The world lays before you undescribed, and yet

editlife.substack.com/p/vibe-codin... Vibe Coding Biology: The Collapsing Cost of Curiosity

Pancreatic Adenocarcinoma Mutation Trajectories at Single Cell Resolution 🧬🖥️ omicsomics.blogspot.com/2026/02/panc...

Anne Frank died from a typhus epidemic that spread through the concentration camp where she was imprisoned.

So, the March for Life appears to have brought Measles to DC. www.nbcwashington.com/news/health/...

Not something you see in textbooks very often: tripolar mitosis.