Saying there's no singular anti-vaccine movement is like saying there are no democrats or republicans. Sure, everyone has a unique viewpoint, but there is an organized and well-funded outfit furthering a specific set of priorities. RFK Jr's $497,000 salary came from somewhere.

Drug-Target Interaction Prediction with PIGLET https://www.biorxiv.org/content/10.64898/2026.02.18.706530v1

Cancer Driver Gene Discovery: A Patient-Level Statistical Framework https://www.biorxiv.org/content/10.64898/2026.02.16.706129v1

PRIZM: Combining Low-N Data and Zero-shot Models to Design Enhanced Protein Variants https://www.biorxiv.org/content/10.64898/2026.02.08.704628v1

Its still so baffling that in the age of Ai and wide access to information, more people are not interested in amateur biology. I'm not even talking bioengineering. Tissue culture, breeding, microbial prospecting, biochemistry, etc. The world lays before you undescribed, and yet

editlife.substack.com/p/vibe-codin... Vibe Coding Biology: The Collapsing Cost of Curiosity

Pancreatic Adenocarcinoma Mutation Trajectories at Single Cell Resolution 🧬🖥️ omicsomics.blogspot.com/2026/02/panc...

Anne Frank died from a typhus epidemic that spread through the concentration camp where she was imprisoned.

So, the March for Life appears to have brought Measles to DC. www.nbcwashington.com/news/health/...

Not something you see in textbooks very often: tripolar mitosis.

I have always liked watching ski jumping and I particularly enjoy watching this opening round of women’s ski jumping because of how long the men at the ski jumping association insisted women couldn’t do it and blocked them for years.

I wonder how many plant species have gone extinct, but their genomic legacy lives on as intact subgenomes of extant allopolyploids.

If this works, we can essentially produce two species out of a single allopolypoid (de-hybridization). If the original donor of a subgenome has already gone extinct, we would be able to de-extinct it for real. Wow. Sounds so cool in my head.

I wonder if we can manipulate meiosis in allopolyploids, such that instead of homologs separating, homeologs separate. Take allopolyploid AABB, normal meiosis generates meiotic products w/ karyotype AB. What if we can manipulate it to make meiotic products w/ karyotypes AA & BB? #PlantScience

How cold is it in Boston for #SLAS2026 ? So cold you can freeze soap bubbles! But it is plenty warm on our autonomous lab tours - still many spots open! And if those don’t work, DM me to discuss alternate times calendly.com/kcarpenter-g...

GPT-5 lowers the cost of cell-free protein synthesis openai.com/index/gpt-5-... Paper (OpenAI + Ginkgo Bioworks): Using a GPT-5-driven autonomous lab to optimize the cost and titer of cell-free protein synthesis (pdf) cdn.openai.com/pdf/5a12a3bc...

📰 GPT-5 Powers Autonomous Lab for Protein Synthesis OpenAI and Ginkgo Bioworks have joined forces to create a groundbreaking autonomous laboratory, where the advanced GPT-5 AI system is directing the optimization of cell-free protein synthesis. This collaboration marks a... #AINews #AI #Teknoloji

New: Washington Post Executive Editor Matt Murray and HR Chief Wayne Connell tell employees to stay home for a zoom webinar ahead of “significant actions across the company.” Widely expected layoffs are scheduled to begin today.

If you are coming to Boston for SLAS, we are offering tours of our autonomous laboratory You can book a tour here calendly.com/kcarpenter-g...

Workflow graphical editor and translator to Nextflow f1000research.com/articles/15-...

Non-coding DNA's Alpha Moment 🧬🖥️ omicsomics.blogspot.com/2026/02/non-...

For anyone interested in the history of molecular biology, I cannot recommend Judson's The Eighth Day of Creation highly enough. One of the great book on the history of science. I have two copies because a actually wore out the first one (paperback) www.cshlpress.com/default.tpl?...

To summarize: Most important Max Perutz was NOT an example of someone with a great idea who went against the establishment wisdom to solve an important problem that he had uniquely identified. He was part of an organized team working on this problem. He got lots of help. 11/14

He said that "All of the professors told him that this was too hard, don't do this... He just ignored them. He putzed around Cambridge and figured it out. And then he figured out the structure of hemoglobin which absolutely transformed hematology." Great story. But completely inaccurate. 3/14

Has anyone read this much hyped paper (I haven’t yet talked myself into posting for access)? What is the nature of the tumor model? I hate to be a wet blanket, but my hunch is this won’t translate anywhere near as impressively to human patients www.pnas.org/doi/10.1073/...

Mmm. So the disagreement we all have with ONT here is *really* about the bigger picture future direction of the company [and the field], not about support for us users. Companies aren't used to getting big picture feedback from users, so they defaulted to answering with a 'fix' for existing users..

ONT claimed that they were primarily making this decision for accessibility reasons. I rejected this claim, because making something a lot more expensive doesn't make it more accessible. If ONT wanted to improve accessibility, it'd be better to offer more support, rather than shut it down.

Other community members said their own experience was that P2 Solo had setup challenges, but was usually fine beyond that. My hypothesis is that many people have setup issues because many are encountering high-throughput sequencing for the first time; the low cost is bringing in new customers.

I wouldn't wish an hour-long podcast featuring Russ Douthat and Jay Bhattacharya on my worst enemy but let's simply say that Podcast Jay still appears more concerned about perceived slights for his COVID crackpottery than with protecting US biomedical science from a full-on Trump-and-RFK onslaught.

Great Trends from the Trenches podcast interview with Thitd Rock Venture’s John Keilty Host Eleanor Howe deftly guides the conversation youtu.be/Elm8Rdxk730?...

Sequencer vs. Library Prep Market Structures 🧬🖥️ omicsomics.blogspot.com/2026/01/sequ...

I don't understand it. ONT seemingly out of the blue announces that the P2s is going to be killed off in 5 months [sales stop 30th June 2026], there's a community backlash, and their appeasement offer is to extend the hardware/software support end date [not the sales stop date] from 2028 to 2030.

P2 Solo: ONT Extends Support But Not Sales 🧬🖥️ omicsomics.blogspot.com/2026/01/p2-s...

P2 Solo: ONT Extends Support But Not Sales 🧬🖥️ omicsomics.blogspot.com/2026/01/p2-s...

Legitimately a feat of carefully calculated writing to issue a Holocaust Remembrance Day statement of this length without mentioning either (1) the people who perpetrated the Holocaust or (2) the people against whom they perpetrated it

People thinking “this is not the time for humor” are ignorant of history. History is filled with moments of peril where the people mock the authoritarians. It undermines their attempt at controlling us. It is vital. youtu.be/I7vb89c6pQY?...

Calling it now: layoffs, doubling down on current strategy, more right leaning content, and reliance on cheap AI slop to cut costs.

ONT Axes P2 Solo, Roiling Community 🧬🖥️ omicsomics.blogspot.com/2026/01/ont-...

Jane Richardson was born #OTD in 1941 + Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures) + MacArthur Fellow, 1985 + Elected, Nat'l Academy of Sciences, 1991 + President, Biophysical Society, 2012 #WomenInSTEM

What lab experiments would *you* like to run remotely on Ginkgo’s autonomous lab? How will *you* unlock biology if you can focus on hypotheses & data and leave the wet work to us? Reach out to me if you’d like to brainstorm!

JP Morgan 2026 Roundup 🧬🖥️ omicsomics.blogspot.com/2026/01/jp-m...

NASA quietly ends financial support for planetary science groups The U.S. space agency will quit funding several independent science advisory groups this year www.scientificamerican.com/article/nasa...

"Confused American family visiting European football stadium can’t find parking lot to get drunk in before the game, ends up in a restaurant."

Bacteria get payback for penicillin 'Here, we demonstrate that bacterial species induce fungal cell wall remodeling to increase exposure of both β-1,3-glucan and mannan, resulting in increased immunogenicity.'

We mourn the passing of Peer Bork, EMBO Member since 2000: https://www.embl.org/news/embl-announcements/in-remembrance-of-peer-bork/

My notes on the #JPM2026 schedule - when the genomics and related companies will be presenting omicsomics.blogspot.com/2026/01/jpm-...

Best TikTok thing going is the two dudes trying food from every country without leaving NYC. If you haven’t seen them yet, it’s incredible. My favorite so far is last week’s. Legit got me emotional.

When polishing scientific figures for publication, I try to limit fonts and font sizes to reduce visual noise. But doing this by hand is very tedious. So I vibe coded a small web app to standardize text in SVGs: jef.works/SVG-Text-Sta... Try it out! Hope it’s useful!

Stalking the Elusive Product Market Fit 🧬🖥️ What drives product success? How do you know if you have the right product in the wrong market? omicsomics.blogspot.com/2026/01/stal...