I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

A nice thing happened.. We got the cover of Nature Genetics! 😊🎉 The spheres trace nuclear stages through early embryogenesis, with color bursts capturing the diverse events that shape genome architecture. Art done by my friend and very talented artist @christophewirtz.bsky.social 🎨

Excited to share my PhD work! The question: How is genome organization established? Here, we developed a low-input Micro-C method, Pico-C, and used it to map chromatin architecture across early stages of fly development. Here’s a quick Blue-torial 🙂 (1/n) www.nature.com/articles/s41...

Congratulations to @nmaziak.bsky.social, @vaquerizasjm.bsky.social et al: Pico-C (low-input Micro-C) shows 3D genome architecture reorganises before major zygotic genome activation in Drosophila, with early loop formation and stronger insulation. @natgenet.nature.com: www.nature.com/articles/s41...

It’s finally out! 😊

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

Do you want to explore the #chromatin of an organism? Join our expert instructors at #LowInput25, and learn how to use low input techniques to support your #epigenomics research at the gene & genome-wide level ⏰Application deadline: 11 February 📎bit.ly/40fdETV #ChromatinSky @nmaziak.bsky.social

I never expected my first post here to be anything but science, yet today we celebrate the fall of a regime that’s brought decades of pain. The joy of this moment is worth sharing a thousand times over.

New blogpost: deevybee.blogspot.com/2024/11/why-...