@hoffsbeefs.bsky.social
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📥 494
📝 1511
cows. genomes.
reposted by
Tyler Wilcox
2 days ago
Tonight on Radio Free
@aquariumdrunkard.com
/
@dublab.bsky.social
— 4-6pm PST. An hour of Neil deep cuts + an hour of 1970s neo-noir grooves. Like this:
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reposted by
Kevin Bird
5 days ago
Happy to see this paper from my time with
@spicybotrytis.bsky.social
out in
@theplantcell.bsky.social
! Amanda, a fantastic PhD student with Dan, led this "phylo-functional" work & uncovered complex duplication & loss of a glucosinolate gene across the Brassicaceae affecting enantiomeric specificity
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Convergence and constraint in glucosinolate evolution across the Brassicaceae
Studying a glucosinolate enzyme across the Brassicaceae shows evolution of plant specialized metabolism involves independent gene losses, distal duplicatio
https://academic.oup.com/plcell/article/37/11/koaf254/8321838?login=false
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I didn't realize this until a week ago
add a skeleton here at some point
6 days ago
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reposted by
Molly Schumer
6 days ago
I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student
@nadiahaghani.bsky.social
and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up:
shorturl.at/NE65A
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Insertion of an invading retrovirus regulates a novel color trait in swordtail fish
For over a century, evolutionary biologists have been motivated to understand the mechanisms through which organisms adapt to their environments. Coloration and pigmentation are remarkably variable wi...
https://shorturl.at/NE65A
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I personally will never forgive him for saying Jews aren't fit for being in agriculture 😤
add a skeleton here at some point
6 days ago
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reposted by
Parker Molloy
14 days ago
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reposted by
Karthik Sankaran
15 days ago
I can’t believe a Stanford dropout invented Berkeley!
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can't stop thinking about the vesias. hate to say it but people need to be open to the idea that this does almost nothing in an awful time to bring them peace. still hoping it turns out okay for all
17 days ago
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ai for good 😁
add a skeleton here at some point
17 days ago
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www.nytimes.com/athletic/675...
😭
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As the Dodgers' relievers put forth a heroic Game 3 effort, they honored Alex Vesia
https://www.nytimes.com/athletic/6758138/2025/10/28/dodgers-bullpen-alex-vesia-honored/
21 days ago
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is time still real I just woke up
22 days ago
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reposted by
Dennis Hogan
24 days ago
Donald Trump wants regime change in Venezuela. The last time the US invaded a Latin American country was in Panama, in 1989, killing hundreds and displacing thousands. Even afterwards, Panama was destabilized. In today’s NYT, I argue an invasion of Venezuela would be far worse.
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Opinion | Trump Wants an Easy Win in Venezuela. He Won’t Get One.
https://www.nytimes.com/2025/10/25/opinion/venezuela-panama-trump-regime-change.html?unlocked_article_code=1.wE8.Jj-B.V2F5tFNFGdQ9&smid=nytcore-ios-share&referringSource=articleShare
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insanity
add a skeleton here at some point
28 days ago
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reposted by
Henry Grabar
about 1 month ago
did somebody steal your Infinity Boss Three this weekend in Cambridge? if so it is in front of my house, come and get it!
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not a dodger fan but I live here and went to 🐐 fest last night.
about 1 month ago
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reposted by
Karthik Sankaran
about 1 month ago
Here's my latest, arguing that the ever-swelling US bailout of Argentina is bad economics, bad politics, and bad diplomacy.
responsiblestatecraft.org/trump-milei/
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What do Americans get for Trump's $40B bet on Argentina?
A massive bailout ahead of the country's legislative elections reveals the high stakes Washington has placed on President Milei's survival
https://responsiblestatecraft.org/trump-milei/
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reposted by
Dani Rodrik
about 1 month ago
In private sector, Bessent made his money by betting that Central Banks would not be able to control their currencies. In government, he is betting that Argentina’s, of all countries, will manage to do so.
add a skeleton here at some point
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youtu.be/p32OEIazBew?...
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Annie Hall (11/12) Movie CLIP - Seems Like Old Times (1977) HD
YouTube video by Movieclips
https://youtu.be/p32OEIazBew?si=a3QK-pciWLJxVT1g
about 1 month ago
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reposted by
Jan Dutkiewicz
about 1 month ago
graphic design and soy are my twin passions
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reposted by
Tanja Slotte
3 months ago
*Postdoc in Evolutionary genomics at Stockholm University* We are recruiting a postdoc for a large interdisciplinary project to investigate evolutionary drivers and genomic consequences of pollen evolution in response to pollination mode shifts in flowering plants. 1/5
su.varbi.com/what:job/job...
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reposted by
Heng Li
about 2 months ago
Do you know ~60% of human SVs fall in ~1% of GRCh38? See our new preprint:
arxiv.org/abs/2509.23057
and the companion blog post on how we started this project and longdust:
lh3.github.io/2025/09/29/o...
. Work with Alvin Qin
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reposted by
Matthew Herper
about 2 months ago
Great news! Experimental gene therapy for Huntington’s markedly slowed disease progression in key trial
www.statnews.com/2025/09/24/h...
via
@statnews.com
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Experimental gene therapy for Huntington’s markedly slowed disease progression in key trial
An experimental gene therapy slowed the progression of Huntington’s disease by 75% after three years — study results likely to support the first approval of a genetic treatment for the condition.
https://www.statnews.com/2025/09/24/huntingtons-gene-therapy-uniqure/
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I'm hiring for some early-mid career wet lab roles in LA we're building the cattle industries top genomics lab.
www.linkedin.com/jobs/view/43...
please share with socal pals! cc
@nmancuso.bsky.social
@docedge.bsky.social
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Grimmius Cattle Company, Inc. hiring Laboratory Scientist- Genotyping in Pasadena, CA | LinkedIn
Posted 3:13:45 PM. About the RoleWe are looking for a motivated Laboratory Scientist to join the genotyping team at…See this and similar jobs on LinkedIn.
https://www.linkedin.com/jobs/view/4303345863/
about 2 months ago
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reposted by
@PrometheusGreen
2 months ago
FDA approves first human clinical trials for gene-edited pig kidney transplants
www.scrippsnews.com/health/fda-a...
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FDA approves first human clinical trials for gene-edited pig kidney transplants
Scientists reached a major milestone in animal-to-human transplant research as the FDA approved the first human clinical trials for kidney transplants from genetically modified pigs.
https://www.scrippsnews.com/health/fda-approves-first-human-clinical-trials-for-gene-edited-pig-kidney-transplants
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well, I live in g and am pretty happy.
add a skeleton here at some point
2 months ago
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I have seen absolutely zero mention of this on linkedin and a lot of... the other story
add a skeleton here at some point
2 months ago
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I have a whirleypop that I love to make popcorn with I just spent five unsuccessful minutes using it because the fan was born directly on me and the stove
2 months ago
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reposted by
Karthik Sankaran
almost 2 years ago
In less than a month, America has gone from “All Politics is Local” to “All Politics is Sokal.”
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reposted by
Jigar Shah
2 months ago
"We are, quite suddenly, living in a world-changing moment" 380 GW of solar deployed in the first half of the year. No other technology can deliver speed to market or anchor the load growth coming the next few years. The US can add 100GW of rooftop solar+ storage in record time.
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Global solar installations surge 64% in first half of 2025 | Ember
https://ember-energy.org/latest-updates/global-solar-installations-surge-64-in-first-half-of-2025/
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reposted by
Heng Li
2 months ago
New blog post – A quick look at Roche's SBX
lh3.github.io/2025/09/11/a...
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#sb79
celebratory pic, here's hoping we can slap some more beautiful neighbors in this pic
2 months ago
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be careful!
add a skeleton here at some point
2 months ago
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reposted by
remarkable recent talk from David Baltimore, who died today, on his career and, well, the state of American science
youtu.be/XqUK3XkaiNU?...
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CSHL Keynote, Dr. David Baltimore, Caltech
YouTube video by CSHL Leading Strand
https://youtu.be/XqUK3XkaiNU?si=_9lPyyB1kykbggIv
2 months ago
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remarkable recent talk from David Baltimore, who died today, on his career and, well, the state of American science
youtu.be/XqUK3XkaiNU?...
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CSHL Keynote, Dr. David Baltimore, Caltech
YouTube video by CSHL Leading Strand
https://youtu.be/XqUK3XkaiNU?si=_9lPyyB1kykbggIv
2 months ago
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reposted by
Adam Phillippy
2 months ago
Definitely hard to measure, but here is our best attempt from a new benchmarking paper to be preprinted in the next few weeks. Element appears to be the current king of homopolymers. Illumina does worse than HiFi beyond 20 bp. (This is all measured on human DNA)
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I want book of job part 7
add a skeleton here at some point
2 months ago
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reposted by
John B. Cole
3 months ago
It's a busy week for manuscripts hitting the journal. First, some nice work by colleagues at NCSU, University of Maryland, and USDA on prioritizing candidate genes associated with complex (quantitative) traits in US Holstein cattle:
doi.org/10.3168/jds....
.
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Redirecting
https://doi.org/10.3168/jds.2025-27058
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being pregnant is terrifying. fuck these monsters
add a skeleton here at some point
3 months ago
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reposted by
Jeffrey Ross-Ibarra
3 months ago
What's the difference between dominance and epistasis? Two physically distinct mutations in a gene interact such that the het is identical to one of the homozygotes. If I define the gene as a locus, we call this dominance. If I define each bp as a locus, we call this epistasis.
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this chart is insane
add a skeleton here at some point
3 months ago
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let's use this
add a skeleton here at some point
3 months ago
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reposted by
Andrew Carroll
3 months ago
I'll be speaking in this webinar (
go.roche.com/sbx-d
) on September 10, where I'll share our benchmarks and observations for Roche's SBX sequencing instrument, as well as models developed by our team for SBX data.
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Germline Small Variant Calling Workflow for SBX Duplex Data
Wednesday, September 10, 2025 at 12:00 PM Eastern Daylight Time.
https://go.roche.com/sbx-d
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reposted by
Hamilton Nolan
3 months ago
The mainstreaming of crypto, the funneling of retirement money into scam assets, the disinterest in concealing direct bribery to our government leaders--these things are symptoms of a newly manic, predatory approach that will cause incredible economic damage.
www.hamiltonnolan.com/p/scams-and-...
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Scams And Bribery Are Becoming the Foundation of Our Economy
It's bad and you should be alarmed.
https://www.hamiltonnolan.com/p/scams-and-bribery-are-becoming-the
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I feel like genetics sky has gotten back to the quality of pandemic era Twitter. all a far cry from pre 2016 genetics Twitter sadly
add a skeleton here at some point
3 months ago
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absolute self sabotage
add a skeleton here at some point
4 months ago
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reposted by
Dan Garisto
4 months ago
For the math folks on here: NSF has suspended Terry Tao's grant.
www.nsf.gov/awardsearch/...
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NSF Award Search: Award # 2347850
Structure theory for measure-preserving systems, additive combinatorics, and correlations of multiplicative functions
https://www.nsf.gov/awardsearch/showAward?AWD_ID=2347850&HistoricalAwards=false
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reposted by
Henry Grabar
4 months ago
I wrote about LA’s 23-bedroom apartments, which are legal, profitable, and spreading like crazy
slate.com/business/202...
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The Double Duplex Is Weird, Overstuffed, and Exactly What L.A. Needs Right Now
City officials tried to rein in McMansions. They got these Frankenstein apartments instead.
https://slate.com/business/2025/07/double-duplex-los-angeles-housing-crisis.html
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reposted by
c0nc0rdance
4 months ago
I NEED to tell you the story of Tae Heung “William” Kim. He's a graduate student at Texas A&M where he's working on a vaccine for Lyme disease. He's a *legal permanent resident* of the United States. And he's been in ICE detention for 12 days & counting, transferred Tuesday to South Texas.
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