I'm hiring for some early-mid career wet lab roles in LA we're building the cattle industries top genomics lab. www.linkedin.com/jobs/view/43... please share with socal pals! cc @nmancuso.bsky.social @docedge.bsky.social

FDA approves first human clinical trials for gene-edited pig kidney transplants www.scrippsnews.com/health/fda-a...

well, I live in g and am pretty happy.

I have seen absolutely zero mention of this on linkedin and a lot of... the other story

I have a whirleypop that I love to make popcorn with I just spent five unsuccessful minutes using it because the fan was born directly on me and the stove

In less than a month, America has gone from “All Politics is Local” to “All Politics is Sokal.”

"We are, quite suddenly, living in a world-changing moment" 380 GW of solar deployed in the first half of the year. No other technology can deliver speed to market or anchor the load growth coming the next few years. The US can add 100GW of rooftop solar+ storage in record time.

New blog post – A quick look at Roche's SBX lh3.github.io/2025/09/11/a...

#sb79 celebratory pic, here's hoping we can slap some more beautiful neighbors in this pic

GOOD NEWS! Researchers have made a HUGE breakthrough towards a UNIVERSAL antiviral. By targeting sugar molecules found on the surface of many viruses that SHARE structural similarities, they identified FOUR compounds that successfully BLOCKED infections from SEVEN different viruses.

be careful!

remarkable recent talk from David Baltimore, who died today, on his career and, well, the state of American science youtu.be/XqUK3XkaiNU?...

remarkable recent talk from David Baltimore, who died today, on his career and, well, the state of American science youtu.be/XqUK3XkaiNU?...

Definitely hard to measure, but here is our best attempt from a new benchmarking paper to be preprinted in the next few weeks. Element appears to be the current king of homopolymers. Illumina does worse than HiFi beyond 20 bp. (This is all measured on human DNA)

I want book of job part 7

It's a busy week for manuscripts hitting the journal. First, some nice work by colleagues at NCSU, University of Maryland, and USDA on prioritizing candidate genes associated with complex (quantitative) traits in US Holstein cattle: doi.org/10.3168/jds.....

being pregnant is terrifying. fuck these monsters

What's the difference between dominance and epistasis? Two physically distinct mutations in a gene interact such that the het is identical to one of the homozygotes. If I define the gene as a locus, we call this dominance. If I define each bp as a locus, we call this epistasis.

this chart is insane

let's use this

I'll be speaking in this webinar (go.roche.com/sbx-d) on September 10, where I'll share our benchmarks and observations for Roche's SBX sequencing instrument, as well as models developed by our team for SBX data.

The mainstreaming of crypto, the funneling of retirement money into scam assets, the disinterest in concealing direct bribery to our government leaders--these things are symptoms of a newly manic, predatory approach that will cause incredible economic damage. www.hamiltonnolan.com/p/scams-and-...

I feel like genetics sky has gotten back to the quality of pandemic era Twitter. all a far cry from pre 2016 genetics Twitter sadly

absolute self sabotage

For the math folks on here: NSF has suspended Terry Tao's grant. www.nsf.gov/awardsearch/...

I wrote about LA’s 23-bedroom apartments, which are legal, profitable, and spreading like crazy slate.com/business/202...

I NEED to tell you the story of Tae Heung “William” Kim. He's a graduate student at Texas A&M where he's working on a vaccine for Lyme disease. He's a *legal permanent resident* of the United States. And he's been in ICE detention for 12 days & counting, transferred Tuesday to South Texas.

Anyways, AIDS is going to be gone soon, this is a generic with FDA full approval.

Can anyone point me to full resolution versions of these classic images from NHGRI that show the growth of GWAS from ~2006--2015? I'm looking for the timelapse versions. (I know many of you are waiting for the GWAS chapters of my free online textbook on human genetics--they are coming, but slowly!)

damn look at that collusion in action 😂

i can fix her

The mother of all front running cycles. Late last year imports starter to pick up, notably from China. The 2018 continued through the next administration but many firms rightly bet that it would escalate via much higher tariffs w/the president’s return. Gains were turbocharged as…

fascinating

Is there a quantitative genetics/evolutionary biology conference happening in Europe between Dec 2025 - April 2026?

Modelling complex traits with ancestral recombination graphs https://www.biorxiv.org/content/10.1101/2025.07.14.664631v1

Here's the total attention to 2025 publications on both X/Twitter and Bluesky. Bluesky has two thirds of Twitter's attention with >10 times fewer users.

New paper published this week! "Herbicides Have Minimal and Variable Effects on the Structure and Function of Bacterial Communities in Agricultural Soils" enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

I will not stay silent. I served this country, and now I’m demanding it do right by me.”

No one has mentioned Grant. Great general, interpreting this as personal loser and unfortunately he very much was. We're lucky he stopped fucking up enough but he was a loser for sure. Loved to get scammed. His father in law didn't respect him and had no reason to until the war. Pretty big drunk.

🚨New preprint is out! How do genetic effects on complex traits change with age? In this work, we compare different approaches to obtain age-varying genetic effects, and show how design and modeling choices can impact the conclusions we draw. shorturl.at/17snd A thread 🧵👇

Large-scale evaluation of proteomic and polygenic risk scores reveals complementary contributions to incident disease prediction https://www.medrxiv.org/content/10.1101/2025.07.10.25331242v1

I am paw-sitively thrilled to say that out latest work is out in Nature today! #Virology #Genomics #Coronavirus #AnimalHealth #InfectiousDisease #Sequencing #FIP #FCoV23 www.nature.com/articles/s41...

🎙️ Just published a new episode of Talking Biotech with Dr. Kevin Folta: A Tribute to Dr. Franklin Stahl and His Elegant Experiment. Have a listen:

@waiterich.bsky.social if you rate this as a ghg tax how efficient is it given all the other products?

Feels like these Brazil tariffs are an instance of a Hegemonic Debtor acting as a Hegemonic Destabilizer.

The Meselson and Stahl experiment demonstrated in 1958 that DNA replicated semi-conservatively. Meaning, each of the two strands of DNA serves as a template for a new copy to made of the complementary strand. Foundational finding, elegant experimental design.

Grinch take but California should ban private fireworks

How plants sense injury in their barrier tissue, periderm? Painstakingly detailed and amazing work by post doc Hiroyuki Iida shows that wounding is sensed by the diffusion of two gases: ethylene and oxygen. @treebiocoe.bsky.social‬ @erc.europa.eu‬ 1/x 🧵 www.nature.com/articles/s41...

Genetically engineered chestnut tree, grown in Syracuse, moves one step closer to release www.syracuse.com/outdoors/202...

PhD student alert: how about working in the industry while at the same time doing a PhD? Here is a fully salaried PhD position at VÄXA Sweden in collaboration with SLU. 🐄🧬🧪. The PhD is on genetic approaches to lower methane emissions in dairy production. English 👇 ledigajobb.vxa.se/jobs/6112392...