bioRxiv Genetics
@biorxiv-genetic.bsky.social
📤 5765
📥 0
📝 2652
Multiple Molecular Pathways to Longevity: Opposing Gene Expression Programs Define Distinct Aging Strategies
https://www.biorxiv.org/content/10.64898/2025.12.29.696944v1
about 11 hours ago
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4
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Mutational analyses reveal PLP-independent functions at PipY, the cyanobacterial paradigm for pyridoxal-phosphate binding proteins
https://www.biorxiv.org/content/10.64898/2025.12.29.696868v1
about 11 hours ago
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1
1
A generalized test of genotype-phenotype causality in population-sampled nuclear families
https://www.biorxiv.org/content/10.64898/2025.12.29.696865v1
1 day ago
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1
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Integrative multiomic analysis on single-nucleotide variants identifies candidate genes for human craniofacial malformation
https://www.biorxiv.org/content/10.64898/2025.12.29.696805v1
1 day ago
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1
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Improved Bayesian inference of hybrids using genome sequences
https://www.biorxiv.org/content/10.64898/2025.12.26.696621v1
1 day ago
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2
1
DNA replication errors drive genome-wide small inverted triplication dynamics
https://www.biorxiv.org/content/10.64898/2025.12.26.696596v1
1 day ago
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3
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Surprising regulatory plasticity for the conserved HOG pathway in diverse Saccharomyces cerevisiae strains
https://www.biorxiv.org/content/10.64898/2025.12.28.696518v1
2 days ago
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Stemness factor Mex3a times translation and protein trafficking to ensure robust differentiation of olfactory sensory neurons
https://www.biorxiv.org/content/10.64898/2025.12.26.696633v1
3 days ago
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0
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Evidence for an ancient master sex determination gene in Hymenoptera
https://www.biorxiv.org/content/10.64898/2025.12.24.696408v1
4 days ago
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DOCK7 regulates WNT signaling and NMJ clustering in normal and DMD muscle
https://www.biorxiv.org/content/10.64898/2025.12.23.696254v1
5 days ago
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The aging transcriptome: a condition-dependent response to a deteriorating soma
https://www.biorxiv.org/content/10.64898/2025.12.22.696078v1
5 days ago
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Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits
https://www.biorxiv.org/content/10.64898/2025.12.23.696273v1
6 days ago
0
8
6
A shared genetic regulator of metabolism and addiction-related behavior in mice and humans
https://www.biorxiv.org/content/10.64898/2025.12.23.696269v1
7 days ago
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Globodera pallida virulence on major potato resistance has a common genetic basis across Western Europe
https://www.biorxiv.org/content/10.64898/2025.12.22.695896v1
7 days ago
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0
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Charting the cognitive development of children using adult 'polygenic g scores'
https://www.biorxiv.org/content/10.64898/2025.12.19.695378v1
7 days ago
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1
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Histological and Metagenomic Analysis of Microbial Communities in Archaeological Human Bones
https://www.biorxiv.org/content/10.64898/2025.12.21.695837v1
7 days ago
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1
1
Longitudinal modelling reveals widespread non-additive genetic effects underlying developmental plasticity
https://www.biorxiv.org/content/10.64898/2025.12.19.695443v1
7 days ago
0
4
1
Barriers to Antimicrobial Resistance Gene Exchange in Methicillin Resistant Staphylococcus aureus Cluster into Transfer Islands
https://www.biorxiv.org/content/10.64898/2025.12.19.694131v1
8 days ago
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0
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Chromosome length is not the sole determinant of sexually dimorphic crossover rates during mammalian meiosis: Insights from genetically diverse mouse strains
https://www.biorxiv.org/content/10.64898/2025.12.19.695521v1
8 days ago
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0
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Genetic Linkage Studies in F2 Cowpea (Vigna Unguiculata (L.) Walp) Mapping Populations Using Qualitative Morphological and SNP Markers
https://www.biorxiv.org/content/10.64898/2025.12.19.695351v1
8 days ago
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0
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COPS5 is Essential for Sertoli Cell Function and Male Fertility in Mice
https://www.biorxiv.org/content/10.64898/2025.12.19.695357v1
8 days ago
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0
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The Paraphyletic Origins of Genetic Resistance to Cabbage Stem Flea Beetle in Brassica oleracea
https://www.biorxiv.org/content/10.64898/2025.12.18.695260v1
8 days ago
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0
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Adipocyte-related genes analysis contributes to the prognosis of atrial fibrillation
https://www.biorxiv.org/content/10.64898/2025.12.18.695292v1
8 days ago
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0
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Evaluation of annual ryegrass genotypes for forage yield and blast resistance
https://www.biorxiv.org/content/10.64898/2025.12.18.695135v1
8 days ago
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1
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A pain-reducing Kv6.4 variant spares other Kv6 channels, offering a target for uterine pain
https://www.biorxiv.org/content/10.64898/2025.12.18.692915v1
9 days ago
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1
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Insertion of rare autism variants in synaptic genes induce novel behavioral phenotypes in C. elegans
https://www.biorxiv.org/content/10.64898/2025.12.19.695228v1
10 days ago
0
6
3
High false sign rates in transcriptome-wide association studies
https://www.biorxiv.org/content/10.64898/2025.12.19.695550v1
10 days ago
0
6
6
Crosstalk between and developmental dynamics of C. elegans Argonaute proteins
https://www.biorxiv.org/content/10.64898/2025.12.17.694999v1
11 days ago
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2
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Structural semantic evolutionary distance (SSED) unifies the selection of cancer driver genes across macroevolution and tumorigenesis.
https://www.biorxiv.org/content/10.64898/2025.12.17.694808v1
11 days ago
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0
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Calorie restriction leads to degradation of mutant uromodulin and ameliorates inflammation and fibrosis in UMOD-related kidney disease
https://www.biorxiv.org/content/10.64898/2025.12.16.694693v1
12 days ago
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0
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Mesodermal-specific MECP2 expression in Drosophila induces visceral and skeletal muscle defects rescued by butyrate supplementation
https://www.biorxiv.org/content/10.64898/2025.12.16.694631v1
12 days ago
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0
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Prevalence, distribution, and mechanisms of genetic dominance in the yeast mating pathway
https://www.biorxiv.org/content/10.64898/2025.12.16.694484v1
12 days ago
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1
1
A target product profile for a rapid diagnostic test to monitor mosquito gene drive presence and frequency
https://www.biorxiv.org/content/10.64898/2025.12.16.694691v1
12 days ago
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0
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LDLR variant classification through activity-normalized prime editing screening
https://www.biorxiv.org/content/10.64898/2025.12.16.694467v1
12 days ago
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2
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Methylphenidate exposure alters brain gene expression and induces transgenerational DNA methylation changes in Poecilia reticulata guppies
https://www.biorxiv.org/content/10.64898/2025.12.16.694564v1
12 days ago
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0
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QTL Identification for Morphological and Phytochemical Traits in 45 F2 Cowpea (Vigna Unguiculata (L.) Walp) Mapping Populations
https://www.biorxiv.org/content/10.64898/2025.12.16.694557v1
12 days ago
0
0
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A Single Genomic Region Controls Primocane Fruiting in Tetraploid Blackberry
https://www.biorxiv.org/content/10.64898/2025.12.15.694498v1
13 days ago
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0
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Genetic activation of ERK2 recapitulates core neurodevelopmental features of Rasopathy syndromes in mice
https://www.biorxiv.org/content/10.64898/2025.12.15.694380v1
13 days ago
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0
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Prior exposure to hypoxia alters DNA methylation patterns in the eastern oyster
https://www.biorxiv.org/content/10.64898/2025.12.15.694390v1
13 days ago
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Ancient genomes from the siege and destruction of Middle Bronze Age Roca Vecchia (Apulia, Italy) shed light on Aegean contacts and conflicts
https://www.biorxiv.org/content/10.64898/2025.12.15.694319v1
13 days ago
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5
1
A Human Genetics Framework for De-risking Gene Editing Targets for Hematopoietic Cell and Gene Therapy
https://www.biorxiv.org/content/10.64898/2025.12.15.694499v1
14 days ago
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0
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Multiparametric Assessment of TNNI3 Variant Phenotypes in Human iPSC-Cardiomyocytes Correlates with Disease Severity in Patients
https://www.biorxiv.org/content/10.64898/2025.12.13.691658v1
14 days ago
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0
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Microsatellite Analysis of Genetic Differentiation Among Populations of the Malaria Vector, Anopheles funestus, across Mainland Tanzania Reveals Contrasted Patterns of Geographic Isolation and Gene Flow
https://www.biorxiv.org/content/10.64898/2025.12.14.694266v1
14 days ago
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1
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Alzheimer disease risk variant rs11218343 determines functional expression of SORL1 in microglia
https://www.biorxiv.org/content/10.64898/2025.12.15.694337v1
15 days ago
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The shifting dynamics of ancestry and culture at a post-Roman crossroads
https://www.biorxiv.org/content/10.64898/2025.12.12.693924v1
15 days ago
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3
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Mitochondrial DNA Imputation Accuracy and Its Application in a Southern African Mitochondrial Genome-wide Association Study
https://www.biorxiv.org/content/10.64898/2025.12.11.693816v1
15 days ago
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0
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Retention of a single Cenp-C gene in different syntenic locations in the montium group of Drosophila species
https://www.biorxiv.org/content/10.64898/2025.12.11.693522v1
15 days ago
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1
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A systems genetics approach to uncover mitochondrial drivers of heart failure reveals mitochondria-nuclear cross talk in genetically diverse mouse strains
https://www.biorxiv.org/content/10.64898/2025.12.12.693865v1
15 days ago
0
1
1
Going Against the Grain: Investigating the C4 Wheat Hypothesis with Spatial Transcriptomics
https://www.biorxiv.org/content/10.64898/2025.12.11.691720v1
16 days ago
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A high-throughput methods SNIPR-Nm reveals small RNA methylation ratio
https://www.biorxiv.org/content/10.64898/2025.12.11.693694v1
17 days ago
0
2
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