A conserved motif in Pch2 regulates its localization and meiotic function in Saccharomyces cerevisiae https://www.biorxiv.org/content/10.64898/2026.06.04.730238v1

Comparative genomics reveals extensive genomic conservation and limited microdiversification among Xenorhabdus bovienii isolates recovered from a single Steinernema feltiae isolation event. https://www.biorxiv.org/content/10.64898/2026.06.04.727993v1

Redox stress agents strongly enhance mutagenesis during horizontal gene transfer in bacteria and leave distinct mutational and metabolic footprints https://www.biorxiv.org/content/10.64898/2026.06.04.730102v1

Complementary Insights from Environmental DNA and Environmental RNA Metabarcoding for Marine Biodiversity Assessment Around San Andres Island, Colombia https://www.biorxiv.org/content/10.64898/2026.06.03.730006v1

Mapping the genetic landscape of the DNA damage response with Cas12a-based combinatorial knockout screens https://www.biorxiv.org/content/10.64898/2026.06.07.728858v1

Cross Potential Selection for Multiple Traits Considering the Progeny Distribution of Future Inbred Lines in Plant Breeding Programs https://www.biorxiv.org/content/10.64898/2026.06.02.729654v1

Gap junctions in the alimentary tract regulate reproductive span in C. elegans https://www.biorxiv.org/content/10.64898/2026.06.03.729750v1

The WormFood CURE: Screening for bioactive metabolites that antagonize the Caenorhabditis elegans Ras signaling pathway https://www.biorxiv.org/content/10.64898/2026.06.03.729853v1

Uncovering moonlighting role of mitochondrial presequence translocase machinery in SOD1-mediated ALS pathogenesis https://www.biorxiv.org/content/10.64898/2026.06.03.729791v1

Genomic Dimensionality Bounds Mixed-Model Association Power and Fine-Mapping Resolution https://www.biorxiv.org/content/10.64898/2026.06.02.729628v1

A collaborative submission model for building high-quality data resources at scale through partnership https://www.biorxiv.org/content/10.64898/2026.06.02.729387v1

Long-read RNA-seq resolves isoform-level and context-specific regulatory architecture of complex traits in cattle https://www.biorxiv.org/content/10.64898/2026.06.04.730050v1

Ultra-Fast Implementation of Multivariate GWAS in Genomic SEM Using Flexible Analytic Estimation https://www.biorxiv.org/content/10.64898/2026.06.03.729606v1

Cytosine base editing workflow for quality-controlled multiplex-knockout hiPSC lines https://www.biorxiv.org/content/10.64898/2026.06.02.729559v1

Fluorescently-labeled split-QF hemidrivers: simplifying and enhancing methods enabling intersectional targeting of discrete cell types https://www.biorxiv.org/content/10.64898/2026.06.01.729389v1

Cyclin C nuclear release and mitochondrial dysfunction define molecular signatures of MED13L Syndrome https://www.biorxiv.org/content/10.64898/2026.06.01.729270v1

PEC: a robust algorithm to reconcile pedigree and SNP-chip data on the basis of LD block, haplotype information, and Mendelian conflicts https://www.biorxiv.org/content/10.64898/2026.06.01.729286v1

A simple method of estimating rabies outbreak sizes from phylogenies https://www.biorxiv.org/content/10.64898/2026.06.01.729206v1

Achiasmatic meiosis underlies propagation of clonal genome and B chromosomes in hexaploid Carassius gibelio females but not males https://www.biorxiv.org/content/10.64898/2026.05.30.728974v1

MAGI: Mechanistic Consequences of Genetic Variants via Genomic Foundation Models https://www.biorxiv.org/content/10.64898/2026.05.31.729117v1

Polynucleotide Phosphorylase Stops Replication Restart by Degrading the RNA within R-loops during Replication-Transcription Conflicts https://www.biorxiv.org/content/10.64898/2026.06.02.729377v1

Molecular characterization of spiny lobsters from the Saint Martins Island, Bangladesh: a new record of Panulirus longipes (A. Milne-Edwards, 1868) https://www.biorxiv.org/content/10.64898/2026.05.29.728916v1

Fine-scale landscape genomics show asymmetric patterns of gene flow for the invasive mosquito Aedes albopictus https://www.biorxiv.org/content/10.64898/2026.05.29.728763v1

Nutrient-responsive and DAF-16/FoxO target H1 histone HIL-1 promotes resistance to starvation and bacterial pathogens in Caenorhabditis elegans https://www.biorxiv.org/content/10.64898/2026.05.29.728887v1

Liver-directed AAV gene therapy metabolically corrects AKU in Hgd deficient mice https://www.biorxiv.org/content/10.64898/2026.06.01.729174v1

POCKET-seq enables genome-wide profiling of on- and off-target transcriptional regulation events by dCas9-KRAB during CRISPR interference experiments https://www.biorxiv.org/content/10.64898/2026.06.01.729390v1

Efficient base editing and development in human embryos without chromosomal alterations https://www.biorxiv.org/content/10.64898/2026.05.30.728989v1

Overexpression of Eaf1, a subunit of the NuA4 lysine acetyl transferase complex, rescues growth defects in the budding yeast H3K36M oncohistone model via histone H4 tail acetylation https://www.biorxiv.org/content/10.64898/2026.05.30.728992v1

Shared binding sites for the chromosomal architectural protein Su(Hw) mediate physical interactions between Drosophila TAD boundaries https://www.biorxiv.org/content/10.64898/2026.05.28.727987v1

Accounting for recurrent mutation in the frequency spectrum of rare alleles https://www.biorxiv.org/content/10.64898/2026.05.29.728884v1

Buffering of developmental noise provides a mechanism for heterosis in both polyploid and diploid hybrids https://www.biorxiv.org/content/10.64898/2026.05.27.728238v1

Mapping genetic risk mechanisms for immune-mediated diseases across human dendritic cell differentiation https://www.biorxiv.org/content/10.64898/2026.05.28.728586v1

The genetics of transcriptional responses to stress in yeast https://www.biorxiv.org/content/10.64898/2026.05.29.728873v1

Identification of Genomic Loci Associated with Cellular Rhythms in Diversity Outbred Mice https://www.biorxiv.org/content/10.64898/2026.05.28.728467v1

Circular RNA-associated QTLs show stronger association with splicing-QTLs than with expression-QTLs https://www.biorxiv.org/content/10.64898/2026.05.29.728707v1

Multispecies Mixtures: An Individual-Centered Quantitative Genetic Framework for Complex Plant Neighborhoods https://www.biorxiv.org/content/10.64898/2026.05.27.728303v1

Development of a CRISPR/Cas9-mediated transformation procedure for the wheat pathogen Zymoseptoria tritici https://www.biorxiv.org/content/10.64898/2026.05.27.728285v1

Selection bias in colony-based microbial mutation accumulation lines https://www.biorxiv.org/content/10.64898/2026.05.28.725302v1

High concordance between genetic effects on mRNA and protein abundance https://www.biorxiv.org/content/10.64898/2026.05.26.727960v1

The D4Z4caster DNA methylation signature identifies individuals at epigenetic risk for developing facioscapulohumeral muscular dystrophy (FSHD) https://www.biorxiv.org/content/10.64898/2026.05.26.727947v1

Decoding causal genes and programs from regulatory variants in aortic valve disease https://www.biorxiv.org/content/10.64898/2026.05.26.727981v1

Active and unusually expanded PIF/Harbinger transposable elements in the Caenorhabditis inopinata genome https://www.biorxiv.org/content/10.64898/2026.05.26.728016v1

AGES for Ageing: Evaluating the auxin-inducible gene expression system for use in Drosophila ageing studies https://www.biorxiv.org/content/10.64898/2026.05.28.728476v1

Mitotree: The Universal Human Mitochondrial Reference Phylogeny at 10x the Resolution https://www.biorxiv.org/content/10.64898/2026.05.28.728540v1

Conditional and marginal SNP-heritability to leverage ancestral and environmental diversity https://www.biorxiv.org/content/10.64898/2026.05.28.728536v1

Stable yet Shifting: Early Toxin Dynamics in Typical and Atypical Clownfish-Anemone Symbioses https://www.biorxiv.org/content/10.64898/2026.05.26.727870v1

A genetic network coordinated by TCP16 and LHY integrates regulation of the vegetative-reproductive phase transition in Arabidopsis thaliana https://www.biorxiv.org/content/10.64898/2026.05.26.727858v1

Dominant resistance alleles accelerate population suppression by CRISPR-based gene drive https://www.biorxiv.org/content/10.64898/2026.05.28.728369v1

A Common Pathogenic Founder Variant in Rwandan Breast Cancer Cases https://www.biorxiv.org/content/10.64898/2026.05.26.727861v1

Cell autonomous inflammation in VEXAS is mediated by cGAS-STING https://www.biorxiv.org/content/10.64898/2026.05.26.727520v1