Hey #genomics and #bioinformatics community: I need an "endorsement" in order to submit a preprint to @arxiv.bsky.social 😭 I'm registered, but can't submit our preprint to q-bio\GN (Genomics) section until we get an endorsement from an existing arXiv author w/endorse privileges. that you? plz DM me🙏

Make art with your hands. It’s what humans do. #noAI #artistssupportingartists #humanart

“Every hour you spend confused is an hour spend building the infrastructure inside your own head that will eventually let you do original work,”… [by using AI tools]… “you haven’t saved time. You’ve forfeited the experience that the time was supposed to give you.” @minaskar.bsky.social

This is a thought provoking metaphysical piece that pulls at the strings of why we care so much (or don’t) as to whether AI can be better at everything than we can be. Absolutely love this. Thanks @aaas.org @science.org 🥰

#ASMicrobe Gold. These are all great people.

What if waste could become a resource? Join Dr. Ryan Bing as he explores how engineered microbes can transform waste feedstocks into valuable compounds. Looking forward to moderating this session! #ASMMicrobe @bioinformer.bsky.social

Biodefense in the Intelligence Age: openai.com/index/biodef... PDF: cdn.openai.com/pdf/biodefen...

Developing a standard definition for sequences of concern: www.frontiersin.org/journals/bio...

#ASMicrobe rumors: attendees climbed out the window of a rooftop bar to retrieve someone’s backpack that had fallen out the window onto a lower rooftop. @tallcuppajoe.bsky.social ?

#asmicrobe 🧐🤩

#ASMicrobe kicking off with the right message.

It’s Pride 🏳️‍🌈 Spare one repost for a small creator? 🥺 My science and sci fi pins raise money for homeless LGBTQ+ people. Just sent another £800 to @aktcharity.bsky.social bringing total to £47,521 New for Pride 2026: 🌈Scientist🌈 🏳️‍🌈🐥🦜🦅🏳️‍🌈 🌈pronouns🌈 www.jamiebgall.co.uk/shop

Once upon a time I was falling in love, but now I'm only falling apart 🎵 The total eclipse of bioinformatics: From disruption to convention, and a gentle warning journals.plos.org/ploscompbiol...

I finally forked up the money to buy an original hardback version of S. Ohno’s infamous 1970 “Evolution by Gene Duplication” it’s wonderful. And I was super surprised and happy to find it had a page torn out of its book review in Science from 1972. 🤩

It’s exciting to go to @asm.org #ASMicrobe but it can be intimidating if it’s your first time or you are alone (and even if you’re not!). We help you have a great meeting through our grassroots peer mentoring program. Join today! 🔬 🧪 🦠 #MicroSky #AMR binningsingletons.com/singleton/bi...

While we slept the DOJ deleted all press releases about charges against January 6 defendants: www.nbcnews.com/politics/jus...

New preprint. I've been chewing on why bacteria have pangenomes for years. Most species carry a distributed gene pool far larger than any one genome holds. E. coli has ~163,000 rare genes across the species. Each individual cell carries about 5,000. Why? A 🧵👇

Paper: doi.org/10.64898/202... Code: github.com/mol-evol/pan... Pushback and alternative readings very welcome.

None of us take pleasure in being right: But we are in the Second Nadir. www.nytimes.com/2025/06/27/m...

It is with great sadness that we announce J. Craig Venter has died. 🧪🧬 www.jcvi.org/media-center...

i feel like society moved on from these too quickly

This work was co-led by myself and Peter Yoon. Structure was led by Peter, @terryzzy.bsky.social , and Trevor Docter. Many thanks to our intrepid collaborators and special thanks to Jennifer for supporting us through this project. www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...

When life imitates art

A “country of geniuses in a datacenter.” - @darioamodei.bsky.social (rereading this essay and it hits different even a few months later.. www.darioamodei.com/essay/the-ad... )

internal discussion about the shoddy job most publications do in describing their bioinformatics methods... and one of my team members replied with this... LMAO.. (used with permission)... so true. 💀

Metadata as infrastructure Curation as design requirements not afterthoughts Reference materials as validation and benchmarking requirements This has to be the way moving forward

I never got to meet Woese, but Ford and Pace have been fantastic to me. Regardless of whether people agree with them, they are/were deep thinkers. No shade to anyone of my generation or the next, but I'm not sure who is similarly gifted.

About to submit a 10k word manuscript with ... zero figures. I'm pretty stoked about this body of work too. Several months of writing between everything else, but courtesy reviews by colleagues have been very positive despite my concerns about our attention span deficient era of social media.

Fun fact: “not a single person on the Wright Brothers team had a college education. They also had zero funding except their own money from their bicycle shop” They were OG hackers.

Friday was my last day at NHGRI. After 10 wonderful years, my lab is headed to Johns Hopkins University genomeinformatics.github.io/movingday/

Post the best photo you’ve ever taken of your pet

Post the best picture you have ever taken of of your pet

Scientific reproducibility, data provenance, metadata gaps are critical issues that are hampering AIxBIO advancements - especially in the ‘Omics space. If you missed my recent talk on this, plz check it out over @labroots.bsky.social www.labroots.com/webinar/repr... #genomics #bioinformatics

I love this so much... and... it's things like this that make the voices in my head go "NERRRRDDDD!!!" 🤣 (for context - this is the W3C provenance model, PROV-DM. If you love this sort of thing... dive in! www.w3.org/TR/prov-dm/)

So i had a penchant for making 1 off limited run tshirts for “conference season”. It seems like each year things kind of get ratcheted up a notch too in terms of snark 🫣😂 So… question for the #microbiome #genomics #bioinformatics community… should I get these made? Would you want one?

I will be participating!

Here's another cool one for tree fans artologica.etsy.com/listing/4409... #sciart

Xylem Vessel, watercolor on cradled wood panel, ready to hang #sciart artologica.etsy.com/listing/4441...

Scientific reproducibility, data provenance, metadata gaps are critical issues that are hampering AIxBIO advancements - especially in the ‘Omics space. If you missed my recent talk on this, plz check it out over @labroots.bsky.social www.labroots.com/webinar/repr... #genomics #bioinformatics

The responses to this post are like pre-X / Twitter level LMAO snark. Omg. Gold.

Lmao… 😂

Nature is publishing papers from cave men now… read the abstract and “resultsnof methods “ sections… 😭 www.nature.com/articles/s41...

One of the earliest mentions of bioinformaticians as a profession... from William Goad's 1978 proposal to create the Los Alamos DNA Data Bank. This was funded and the "data bank" was created in 1979 - and later became GenBank in 1982. #science #history #genomics #bioinformatics

We’re starting to treat biology as data infrastructure, but we all know biology doesn’t start as data. The America’s Living Library Act explicitly pairs large‑scale sequencing w/long‑term stewardship + curation of physical samples. That’s the foundation we need. www.atcc.org/blogs/2026/a...

ATCC Genome Portal's 2026 Q1 Release is live! New #genomics #RNAseq #methylation #AMR data! +80 human cell lines, +7 organoids, +206 bacteria, +26 viruses, +20 fungi, including 3 new MDR strains of Candida auris (Candidozyma auris). AGP now has >3600 DNA methylation profiles too! genomes.atcc.org

End of the line... #virology #genomics

I had this weird idea: "What if we could measure the scientific impact of things, materials, reagents, even ideas in science?" So... i wrote a tool that basically treats terms like "authors" and calculates various impact metrics. Results are surprisingly interesting... github.com/jonathanjaco...

This week be like…

First fully phased reference genome for the Yarrowia liploytica type-strain is out! academic.oup.com/jimb/advance... Super fun project in collaboration with James Crill at Syracuse University as well. Important platform organism for industrial microbiology and biomanufacturing as well. #genomics

First fully phased reference genome for the Yarrowia liploytica type-strain is out! academic.oup.com/jimb/advance... Super fun project in collaboration with James Crill at Syracuse University as well. Important platform organism for industrial microbiology and biomanufacturing as well. #genomics