ICYMI: New online! Microbial ecology and evolution in the genomics era

FYI: New online! Detecting transcription factor binding sites with PADIT-seq

FYI: New online! Understanding microbial ecology and evolution with single-cell genomics

FYI: New online! Dissecting pleiotropy to gain mechanistic insights into human disease

Transcriptomics in the era of long-read sequencing #Review by @carolinamonzo.bsky.social, Tianyuan Liu & @anaconesa.bsky.social @conesalab.bsky.social @csic.es Free to read here: rdcu.be/efBjP

Our Review article is now featured in the January issue of @natrevgenet.nature.com, check it out!

New online! Microbial ecology and evolution in the genomics era

📢 Our January issue is live and it's a special one🦠🧫! Featuring a range of article types, including Reviews, Comments and Journal Club articles, this Focus issue explores the insights gained from the application of microbial genomics within ecological and evolutionary contexts go.nature.com/3MNmsgR

Lovely is the right adjective. Writing this was so enjoyable in the company of @acstone.bsky.social @blevinske.bsky.social and Verena Schuenemann. Hope you enjoy.

Lovely to work with @blevinske.bsky.social, @paleogenomics.bsky.social & Verena Schuenemann on " Ancient DNA insights into diverse pathogens and their hosts"! Read it at rdcu.be/eSVPN

Our January issue is live! A Focus issue on viral pathogen evolution and global health. The issue explores viral emergence, adaptation, spread, and strategies for surveillance and preparedness to detect and control evolving viral threats. Read more: www.nature.com/collections/...

Here, @amywebster.bsky.social & @patrickphillips.bsky.social review the role of genetic and environmental causes in shaping epigenetic regulation at three timescales: among individuals within a generation, across one or multiple generations and sustained over evolutionary time go.nature.com/4pXiKQ4

ICYMI: New online! Ancient DNA insights into diverse pathogens and their hosts

2025 in Nature Reviews Genetics covers - a huge thank you to our brilliant art editor Pat Morgan, who does all the artwork for the journal and is a fantastic colleague and very talented artist!

A Review in Nature Reviews Genetics examines the current state of implementation of polygenic risk scores in the clinical setting, highlights key challenges and outlines future directions for the use of such scores to improve disease risk prediction and to enable personalized prevention. 🔒

Transcriptomics in the era of long-read sequencing Free to read here: rdcu.be/efBjP

New online! The regulation and function of post-transcriptional RNA splicing

FYI: New online! Harnessing artificial intelligence to advance CRISPR-based genome editing technologies

FYI: New online! Harnessing evolution to infer protein networks

Free to read here: rdcu.be/eJ9E4

ICYMI: New online! Detecting transcription factor binding sites with PADIT-seq

ICYMI: New online! Dissecting pleiotropy to gain mechanistic insights into human disease

ICYMI: New online! Understanding microbial ecology and evolution with single-cell genomics

New online! Ancient DNA insights into diverse pathogens and their hosts

Free to read here: rdcu.be/d64zN

FYI: New online! Nascent transcription quantification with scFLUENT-seq

New online! Detecting transcription factor binding sites with PADIT-seq

New online! Understanding microbial ecology and evolution with single-cell genomics

New online! Dissecting pleiotropy to gain mechanistic insights into human disease

Free to read here: rdcu.be/d64zN

For #worldmicrobiomeday, re-sharing our recent Review by @yishay.bsky.social & Ami S. Bhatt on the 'Sequencing-based analysis of microbiomes', which is free to read using this link: rdcu.be/etIUM

Walking around the office looking for a print copy yesterday... "Oh yeah, I saw your Stranger Things cover over there..." 😁

FYI: New online! Genomics of drug target prioritization for complex diseases

Functions of RNA m6A methylation at the molecular, genomic and organismal level: go.nature.com/484M6pB Free to read here: rdcu.be/eR4zx

Successful drug development depends on identifying effective targets and optimizing drug design and clinical trial strategies. The authors review computational strategies, including ML, for integrating genetics into pharmaceutical pipelines go.nature.com/4pzCMjs

All you need to know about DNA-based recording and how molecular recording can transform the way we study developmental and disease processes The lives of cells, recorded go.nature.com/3XYVh4V Free to read here: rdcu.be/d1s8d

Review: The lives of cells, recorded https://www.nature.com/articles/s41576-024-00788-w (read free: https://rdcu.be/d1s8d) 🧬🖥️🧪

ICYMI: New online! Harnessing artificial intelligence to advance CRISPR-based genome editing technologies

ICYMI: New online! Harnessing evolution to infer protein networks

FYI: New online! Convergent evolution of a conserved molecular network underlies parenting and sociality

Want to know about using machine learning for alternative splicing predictions? Read our recent Review: From computational models of the splicing code to regulatory mechanisms and therapeutic implications go.nature.com/4oYCL8N (free to read here: rdcu.be/dVNV4)

Free to read here: rdcu.be/eLxK7

Review: Inference and applications of ancestral recombination graphs https://www.nature.com/articles/s41576-024-00772-4 (read free: https://rdcu.be/dVyQH) 🧬🖥️

FYI: New online! Microbial genomics for antimicrobial resistance ecology and action

FYI: New online! Decoding the regulatory genome with large-scale deep learning

FYI: New online! From clonality to complexity: a journey through microbial ecology and evolution

FYI: New online! Average nucleotide identity — the backbone of modern ecological genomics

A Consensus Statement in Nature Reviews Immunology clarifies the existing subset-based nomenclature for T cells. It also proposes an alternative modular nomenclature that is designed to be brief and flexible and to avoid ambiguity and unwanted implications. go.nature.com/3Xzfoqb #immunosky 🧪

Our December 2025 issue is now live: go.nature.com/3Lx0PB0 Topics include: the evolution of transcriptional regulatory mechanisms in animals; cell-type deconvolution methods for spatial transcriptomics; fine-mapping of candidate causal variants; and genomics of psychiatric disorders

New online! Harnessing evolution to infer protein networks