New Article! Sensing and perturbing mammalian cell states with reprogrammable ADAR sensors (RADARS)

New Article! APEX-seq maps transcriptome-wide subcellular RNA localization in living cells

New Article! Patient-derived ependymoma and medulloblastoma tumoroids: generation, biobanking and drug screening

New Article! Electrocatalytic reactions involving aqueous nitrate and nitrite

New Article! Tracking-seq: a universal off-target detection approach for CRISPR–Cas genome editing

New Article! Preparation of an activatable benzothiadiazole-based nanoprobe for multispectral optoacoustic and NIR-II fluorescence dual-mode imaging of liver injury

New Article! Live-cell imaging of RNA dynamics using bright and stable fluorescent RNAs

New Article! Exploring proteins and protein–ligand complexes through residue interaction networks

New Article! Establishing and analyzing the Simplified Human Intestinal Microbiota (SIHUMI) as a versatile in vitro gut microbiome model with qPCR-based strain-level tracking

New Article! Establishing a long-term versatile culture system for functional mouse mammary organoids from single cells

New Article! Ligand-assisted interfacial monomicelle assembly to incorporate intermetallic nanoparticles into mesoporous carbon nanostructures

New Article! The HOST assay: an automated video-based evaluation of mosquito attraction to thermal infrared

New Article! Preparation of ENBSe-based photoredox catalysts for O2-independent phototherapy in living systems

A protocol for the preparation and evaluation of placenta-tropic mRNA LNPs for treating pregnancy disorders. 🧪 @natprot.nature.com

Want to image apoplastic pH in plants? 🔬 Two new papers from our team offer a full workflow plus open access analysis tools. Congrats to @aroessling.bsky.social, Niklas Mayle and @lguerard.bsky.social Nature Protocols: rdcu.be/e7R2E BMC Methods: lnkd.in/dctpWJ3X Happy Imaging!

New Article! Quantitative imaging of apoplastic pH in plant roots via confocal microscopy

New Article! FuzDrop: sequence-based prediction of the propensity of proteins for liquid–liquid phase separation and aggregation

New Article! Preparation of placenta-tropic mRNA lipid nanoparticles for pregnancy disorders

New Article! Preparation of targeted lipid nanoparticles for precision nucleic acid delivery

New Article! Plasma-coupled electrochemical ammonia synthesis from air and water under ambient conditions

New Article! A scalable, low-cost, sample hashing workflow for multiomic single-cell analysis using the Seq-Well S3 platform

www.youtube.com/watch?v=GhFd... There is even some methodological information at the end. Just beautiful.

Our Opening Doors Internship Programme is open for applications! #BePartOfProgress and join one of our teams to gain hands-on experience working on impactful projects and benefit from the expertise of our talented colleagues. spklr.io/63327DL797#BePartOfProgress #Publishing #WorkInPublishing

New Article! A new era for coral functional genomics

New Article! Efficient genome editing using CRISPR–Cas9 in reef-building corals

New Article! Oscillatory brain state-dependent stimulation with transcranial magnetic stimulation combined with electroencephalography

Did you read our paper applying SUM-seq in macrophages, T-cells and iPSCs (www.nature.com/articles/s41...) and think: I want to try this cost-effective single cell RNA & ATAC-seq method myself? 🧬 Find the complete protocol including tips, troubleshooting and timing now in Nature Protocols

There is a paid internship for aspiring science journalists at Nature's London office. Up to three days a week working from home. All the details are here (deadline 9 March): springernature.wd3.myworkdayjobs.com/en-US/Spring...

A new series of 'How to' Comment is now launched! It provides guidance & practical recommendations for topics of broad interest to our readership. Read our editorial about it:

New Article! Single-cell ultra-high-throughput multiplexed chromatin accessibility and gene expression sequencing (SUM-seq)

New Article! 3D hierarchically aligned nanofiber scaffolds promote cell migration for tissue regeneration

New Article! Volumetric DNA microscopy for mapping spatial transcriptomes in three dimensions

New Article! Aqueous sonochemical synthesis of covalent organic frameworks

New Article! High-throughput reaction screening using acoustic ejection mass spectrometry

New Article! Harnessing intermediate-scale bioreactors for next-generation macrophage production and application

Super happy to share our protocol for ENGRAM is out in Nature Protocols! This was fun to write with @chenomics.bsky.social @troymcdiarmid.bsky.social @jshendure.bsky.social. In it we describe how to record CRE identity, activity, and order in mammalian cells.

New paper just out, based on new ISO method for animal-free food protein digestibility/DIAAS method. Lead-authors R. Portman and L. Egger, great long-term effort. I am so happy to be part this process #infogest @vistamilk.bsky.social #giantleaps @csic.es @researchireland.ie @teagasc.bsky.social

Check out our new protocol paper on molecular recording of transcriptional events in genomic DNA! Super fun pulling this together with @jennynathans.bsky.social @chenomics.bsky.social and @jshendure.bsky.social

New Article! Preparing and characterizing environmentally aged microplastics

New Article! Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa feeding infection

New Article! High-throughput identification of endogenous biomolecular condensates and phase-separating proteins

New Article! Multichannel genomic recording of biological information with ENGRAM

New Article! Simplified ischemia-free liver transplantation with continuous normothermic machine perfusion

New Article! Designing and testing CRISPRi-based synthetic gene circuits in plants

New Article! Conjugation of hydrophobic drugs to motile pRNA 4WJ nanoparticles for spontaneous tumor targeting and undetectable toxicity

New Article! Secreted luciferases as a minimally invasive 3R-compliant tool for accurate monitoring of tumor burden

New Article! INFOGEST Quant: standardized in vitro determination of digestibility and DIAAS of dietary proteins based on the INFOGEST static digestion model

New Article! Magnetoencephalography in human neuroscience research: planning, piloting, implementation and quality assurance

New Article! Direct delivery of assay reagents to extracellular vesicles in liquid biopsies for biomarker analysis

New Article! Integrated fluorescence light microscopy-guided cryo-focused ion beam-milling for in situ montage cryo-ET