This is super impressive and interesting #TeamTomo work by @carter-lab.bsky.social. Congrats everyone!! 🧪 🧶🧬

#TeamTomo if you want to use CTF-corrected 3D subtomos from AreTomo3 in RELION v.5.1 you can use this updated script: github.com/Phaips/aretomo3torelion5

Before knowing anything else about this, I am excited because prediction of stoichometry is also an implicit prediction of allostery.

New protein complex stoichiometry prediction tool from talent PhD student @daniil-litvinov.bsky.social, check out the thread below!

Check out this awesome work from @daniil-litvinov.bsky.social: Protein complex stoichiometry prediction (both homomers and heteromers) from sequence, with some nice ablations showing what makes the difference!

Stoic 🦾 from our shared student @daniil-litvinov.bsky.social predicts protein complex stoichiometry. A fun collab with @ninjani.bsky.social @torstenschwede.bsky.social - this #AI adventure beyond our core #CryoET methods was made possible by the @biozentrum.unibas.ch PhD Fellowship Program! 🧪 🧶🧬

started using --𝐬𝐢𝐠𝐦𝐚_𝐚𝐧𝐠 𝟑 in RELION5 Refine3D and all of a sudden every subtomogram average goes to high resolution 🤯 #TeamTomo

This is a proud and exciting moment for me. Manon continues to redefine our understanding of pyrenoid biology, as she pushes the frontiers of #TeamTomo straight into the natural world around us 🌍🌊🌾🔬 Her new group at @gmivienna.bsky.social will explore fresh and impactful questions. Check it out! 🧪👩‍🔬

Exciting opportunity to work in a lab that’s pushing the boundaries of environmental sampling and work with an amazing scientist!!! 👩‍🔬🔬

You want to work on carbon concentration mechanisms in algae 🫑? Go work with my (soon-to-be-former) colleague @manondemulder.bsky.social in Vienna @gmivienna.bsky.social ! Cryo-ET 🔬 and funky bugs 🦠 #CryoET #CryoEM

I mean Vienna is not a bad place to be, but working and building and expanding and Cryo-ETing with @manondemulder.bsky.social can only make it a billion time better....

A bit late to the party- but this is one of the finest papers I have read in years. It is both super cool science, and does the near impossible in our field: grounding insights about the evolution of molecular mechanism in the ecological arena in which they (presumably) arose. It's a masterpiece.

#TeamTomo is in the museum #SciArt 🧪 🎨

So it turns out that chromatin in archaea takes the hellish form of a Lovecraftian tube worm 🪱🔥 Love it! Thanks for the nightmare-fuel! 😱 #ArchaeaSky @dodonova-sveta.bsky.social 🧪

@embl.org at its best: collaborative, open, transformative, and just the right amount of crazy. Dreaming of mechanistic cell biology *in the natural environment*? Dream no more, rent the AML. www.biorxiv.org/content/10.6... www.youtube.com/watch?v=jepb... #WeFreezeOnTheBeach #ProtistsOnSky 🦠🌍🧪

So one day, I walk into our lab and @computingcaitie.bsky.social & @abimoye.bsky.social are carying eyeballs around everywhere 👀. Thanks for the eye-opening collaboration! (literally, ha!) 🧪

Great to see our paper on light-intensity dependent swimming patterns in #Chlamydomonas out now in Phys Rev Lett. as an Editors' suggestion! With a nice commentary by @philipcball.bsky.social. Chlamy actively modulate the beat planes of their #cilia! journals.aps.org/prl/abstract... #protistsonsky

Very cool environmental #CryoET. This is an exciting frontier for #TeamTomo 🧪 🌍

Chloroplast-encoded small subunit extensions reshape the Chlamydomonas chlororibosome www.biorxiv.org/content/10.64898/2026.02.07.704542v1 #cryoem

This is absolutely gorgeous work from @helenfoster.bsky.social, @margotriggi.bsky.social, @gaiapigino.bsky.social and colleagues 🤩 #Chlamy cilia never cease to amaze!

At long last, the Chlamy chloroplast ribosome hat 🎩 (now renamed the arm 💪) is here to say hello👋! We first spotted this extended structure in green algae a decade ago, and @florentwaltz.bsky.social did beautiful work bringing it into focus! #CryoEM ❄️ #TeamTomo 🔬 #PlantScience 🌾 #ProtistsOnSky 🧪

For #ECR’s: DBG’s Hot Tpoic Workshop on Cryo-Electron Tomography + FIB-milling 13 – 15 April 2026 In @cellarchlab.com 's lab @biozentrum.unibas.ch Organised by @tamb-o.bsky.social, Karen Zinzius, @fannyleblanc.bsky.social Details: www.deutsche-botanische-gesellschaft.de/en/about-us/...

Our new paper, out today! We resurrected ancient nitrogenases first used by life on Earth 3 billion years ago. We combined synthetic biology and geology & validated their chemical #biosignature in rocks that helps reveal ancient life on Earth!(and beyond!) Link: www.nature.com/articles/s41...

Check this new study on carbon concentration mechanisms! See how the pyrenoid changes by modifying Rubisco linkers in our favorite alga, Chlamy 💚! My desk mate @phaips.vd.st spent a lot of time collecting & carefully analyzing these beautiful tomograms 🔬. Congrats to all the authors!

That is a really beautiful poster!🤩 🧪 Inside the Pyrenoid: How Multivalency Shapes Rubisco Organization and CO2 Fixation www.biorxiv.org/content/10.6...

You like #LLPS? #TeamTomo? #Rubisco? Check out our latest preprint! What a great collaboration this has been!

Check out this cool thread on the latest preprint by Gaurav Kumar, @james-r-barrett.bsky.social, @phaips.vd.st from our lab and colleagues, dissecting the physics of Rubisco condensates! You're in for some stunning #cryoET of the pyrenoid - in Chlamy, of course 😉 Congrats to all involved!

Excited to share this detailed biophysical study of #PhaseSeparation in the Pyrenoid, an algal microcompartment that fixes a third of the Earth's #CO2 🌏. We combine methods across scales, in vitro 🧪 and in vivo 🦠 Thanks for the very fun collaboration! 🤗 #PlantScience 🌾 #TeamTomo 🔬 #LivingPhysics 🧬🧶

How do diatom cells maintain a constant supply of carbon for photosynthesis? Our microelectrode measurements of the phycosphere around individual diatom cells show that diatoms can rapidly switch between distinct carbon acquisition pathways. @thembauk.bsky.social www.science.org/doi/10.1126/...

#TeamTomo visualizes amazing (green 💚♻️) proteasome crystals in yeast. This project was a long time coming -- I remember talking to Cordula about it back when I was a postdoc in Martinsried. Some really cool and surprising findings here. Nice to see it out, and congrats to all the authors! 🧪 🔬

SHAPES being the key word, amirite @nanigrotjahn.bsky.social github.com/GrotjahnLab/... Should be an interesting #TeamTomo talk. Check it out! 🧪 🔬

Go #TeamTomo! 🧪 @wilflinglab.bsky.social & @nanigrotjahn.bsky.social are on a roll! Beautiful in-cell visualization of lysosome rupture 🎈💥

One of the best #TeamTomo studies of phase-separated condensates I’ve seen. I am reminded of Rubisco condensates (pyrenoids) for the ability to make such quantitative measurements of molecular organization. It really helps to have intrinsic ~500 kDa fiducials. Awesome mechanistic stuff!! 🧪 🧶🧬 🔬

This large-scale open dataset and the continued community development around it exemplify the spirit of #TeamTomo 🧪 🔬 👨‍🔬👩‍💻

This large-scale open dataset and the continued community development around it exemplify the spirit of #TeamTomo 🧪 🔬 👨‍🔬👩‍💻

I'm so happy to have gotten the opportunity to work on this project and I'm SO excited that they selected our image for the cover!

What a great example of collaborative science enabled by people sharing things early on. Well done @lifeonthewedge.bsky.social and others!

The #ChlamyDataset is on the cover of @cp-molcell.bsky.social 🖼️🥰! Read @lifeonthewedge.bsky.social's great thread🧵 for the inside scoop🍨 on all the #TeamTomo developments already made possible since these 1829 tomos hit EMPIAR 🧪 🧶🧬 For more, here's the old preprint thread: bsky.app/profile/cell...

#teamtomo gets another quantitative cell biology tool! We extend our Surface Morphometrics pipeline to measure membrane thickness. Alongside many biological findings, we show that our 3D measurements closely match in vitro vesicle measurements from 2D EM (collab w/Neal Waxham and Fred Heberle).

ER-associated single-capped vaults are surprising and really cool!🤩 Some even contain ribosomes. Vault function is still mysterious but a role in protein quality control seems plausible. Also great to see Dicty in the #TeamTomo spotlight! #ProtistsOnSky @kgeissler.bsky.social @becklab.bsky.social 🧪

Another #notTHECover unfortunately. But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab. Read here: www.cell.com/cell/fulltex...

EMPIAR-11830 #ChlamyDataset #TeamTomo 🧪 www.cell.com/molecular-ce...

Really excellent work by the bluesky-less Marie and Sara +coauthors in our lab @embl.org! Check it out for cool combinations of light microscopy and #cryoET, and if you're interested in how yeasts reorganize structurally in response to stressors. #teamtomo

A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social. Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...

Final version is out! Our large-scale cryo-ET dataset 🔬 of Chlamydomonas reinhardtii 🦠 is now published in @cp-molcell.bsky.social Huge collaborative effort! So glad to see the community already using it to develop new resources & tools. Check it out here: shorturl.at/z4i4c #CryoEM #CryoET

Happy to see IsoNet2 performing so well on the #ChlamyDataset EMPIAR-11830. Congrats to the authors really great work. However, I have to say this tomogram looks amazing because the lamella is way too thin (~50 nm) and not vitreous! 🫠 www.biorxiv.org/content/10.6...

Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6... Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet

Postdoc opportunity with Michel Goedert and myself to work on #cryoEM/#cryoET structures of #amyloids. Feel free to email me with any questions you might have. mrc.tal.net/vx/mobile-0/...

🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.

Thrilled to share that my postdoc paper has just been a published in @plosbiology.org ! Thank you to all co-authors, and a special thanks to Paul and Virginie @centriolelab.bsky.social for their support throughout this work. Proud of what we achieved together! journals.plos.org/plosbiology/...