Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!

For #ECR’s: DBG’s Hot Tpoic Workshop on Cryo-Electron Tomography + FIB-milling 13 – 15 April 2026 In @cellarchlab.com 's lab @biozentrum.unibas.ch Organised by @tamb-o.bsky.social, Karen Zinzius, @fannyleblanc.bsky.social Details: www.deutsche-botanische-gesellschaft.de/en/about-us/...

You like #LLPS? #TeamTomo? #Rubisco? Check out our latest preprint! What a great collaboration this has been!

Cilia alert! Stoked to have the new paper from Juyeon Hong about a new domain at the extreme distal tip of motile cilia! (The EDT, y'all!) It's out now @natcomms.nature.com. Check it out! #cilia www.nature.com/articles/s41...

🔬🚨New preprint alert! 🚨🔬 We developed quantitative expansion microscopy (qExM) - a method to accurately count proteins in situ by combining expansion microscopy's improved labeling with statistical estimators borrowed from ecology www.biorxiv.org/content/10.6... #SuperResolution #CellBiology

Our research scientist Núria Ros-Rocher won the 1st prize @zeiss-microscopy.bsky.social microscopy contest with this beautiful choano colony www.zeiss.fr/microscopie/... 🥳 C. flexa might not yet be a genetic model, but it is now at least a calendar model, which counts for something. I think.

This one was quite the journey! The paper describing the #ChlamyDataset is finally out and on the cover of Mol Cell! This beautiful rendering made by co-author @jessheebner.bsky.social and Holly Peterson shows an instance of mitochondrial fission found in the dataset 😍 [Maybe long thread ahead]

Final version is out! Our large-scale cryo-ET dataset 🔬 of Chlamydomonas reinhardtii 🦠 is now published in @cp-molcell.bsky.social Huge collaborative effort! So glad to see the community already using it to develop new resources & tools. Check it out here: shorturl.at/z4i4c #CryoEM #CryoET

Happy to share our fun team-up with @centriolelab.bsky.social & @stearnslab.bsky.social to reveal the architecture of the mammalian centriole’s Distal Ring 🛟. Very cool multiscale integration of #UExM 📏🔬with #CryoET ❄️🔬. Congrats to @ebertiaux.bsky.social & @computingcaitie.bsky.social #TeamTomo 🧪

Great talk (and work 🧪 ) by @computingcaitie.bsky.social from @biozentrum.unibas.ch about exploring multiciliated cells with a complementary trio of structural techniques! Looking forward to sharing the preprint. Thanks for the fab collab @centriolelab.bsky.social @stearnslab.bsky.social #TeamTomo

Tomorrow!!

While trying to steer clear of the ‘best organelle’ debate, we’re delighted to highlight #JCSciliaSI, guest edited by @cilialab.bsky.social & @lottepedersen.bsky.social. And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!

Super happy this work is out and included in the really interesting cilia and flagella focused issue!

🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny. #ProtistsOnSky #SciComm #SciSky www.cell.com/cell/fulltex...

Our Special Issue on Cilia and Flagella: from Basic Biology to Disease, guest edited by @cilialab.bsky.social‬ and @lottepedersen.bsky.social, is building. We’ll be highlighting all the articles over the next couple of weeks. Follow along at #JCSciliaSI. journals.biologists.com/jcs/issue/13...

A class like no other!! From #AI structure hallucination 🤖 to #CryoEM structure reality 🔬 by @biozentrum.unibas.ch @unibas.ch undergraduate students👩‍🔬👩‍🎓 in just a few weeks! One of their creations is this beautiful flower-shaped tetrameric pore 🌼, a brand new member of the #ProteinCosmos 🧶🧬 🧪

That’s a wrap of the 2nd edition of our one of a kind structural biology block course at the @biozentrum.unibas.ch! In just 6 short weeks students designed protein oligomers; rotated in cryo-ET, cryo-EM SPA, AFM, and NMR labs; and expressed, purified, and structurally characterized their designs

Mark your calendars for some cilia science!!!

Last Friday (17th), we had an amazing first Young Swiss Tomo meeting in Bern, organized with Elda Bauda, Zanetta Kechagia, and @leonieanton.bsky.social! Over 70 people from 🇨🇭 gathered to talk about cryo-electron tomography 🔬. Huge thanks to the DCI for making the event possible! See you next year! 👋

Latest from ours: www.cell.com/cell-reports... This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵

So much fun to host @edwardmarcotte.bsky.social at the @biozentrum.unibas.ch and introduce him to the @cellarchlab.com, thanks for a wonderful Discovery Seminar!!

Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging www.biozentrum.unibas.ch/open-positio... #biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging

You don’t want to miss this one!

Meet the CAGE: a newly-discovered protein nanocapsule💊, conserved from bacteria to eukaryotes! Looks more like an eclair🍩 than a prezel🥨. This protein pastry now makes us wonder- what's the filling!? Huge congrats to the ever-amazing @computingcaitie.bsky.social, now at the @biozentrum.unibas.ch 🧪🧶🧬

I am excited to share our new preprint on the CAGE complex, a mysterious hollow protein complex that I first saw years ago while surveying Tetrahymena ciliary lysate www.biorxiv.org/content/10.1... #cilia #protistsonsky 🧬🧪

A molecular-resolution look into the near-native architecture of the spinach chloroplast🌱. This one was a long time in the oven, but we're happy to finally share our "version of record". What long-standing debates did we settle? Check back for a short thread🧵 on Monday. #TeamTomo #PlantScience 🧪🧶🧬🔬🌾

Side hustle level-up! My book, IN THE BEGINNING, will be published by @harperonebooks.bsky.social in 2027! It's about the human embryo, how it gets built, and what it means for where we come from and where we're going. @harpercollins.bsky.social (1/2) @socdevbio.bsky.social #devbiol #scicomm

Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social www.biorxiv.org/cgi/content/... @mrclmb.bsky.social @wellcometrust.bsky.social

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1... Soon at @spirochrome.com Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

For some three billion years, unicellular organisms ruled Earth. Then, around one billion years ago, a new chapter of life began go.nature.com/3JyRV4S

Apply now for the prestigious and independent #BiozentrumPhDFellowships. Great science. Unique rotation-based selection of research group and other incentives. The summer call is open until October 12, 2025. bit.ly/4caiqqX @biozentrum.unibas.ch @unibas.ch #fellowship #PhD#Switzerland

📢 Excited to share our new study in Nature Communications! We show that the A-C linker safeguards centriole architecture & controls duplication. A big congratulations to Lorène for this beautiful discovery, which represents 4 years of her thesis work. www.nature.com/articles/s41...

‼️🚨Preprint alert! 🚨‼️ Excited to have some of my first works as a postdoc, and first corresponding author (!!), on biorxiv! This was a fun side quest of a project marrying a few things I deeply love, development, cilia, and hormones in the pituitary! Happy reading! www.biorxiv.org/content/10.1...

Such a pleasure to be co-organising the #Latsis Symposium this year with Guillermina ! Thanks to all the speakers & sponsors. And all our teams members who helped make this a reality. It just felt right. #Science #WildCells #ProtistsOnSky #Cell #Biology #Biophysics #Behaviour

Wow! Really nice collaborative work in this piece on RSG1 in human ciliopathy and transition zone assembly

Woo! Very excited to share our collaborative work on the centriole's Luminal Distal Ring ⭕. This project started 13 years ago with @hugovdhoek.bsky.social & @stearnslab.bsky.social, and then beautifully came together with @computingcaitie.bsky.social & @centriolelab.bsky.social. #TeamTomo #UExM 🧪🧶🧬🔬

90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO

We’re kicking off the DinoSphere Online Seminar Series! Join us for our first session with Karel Mockaer (Heidelberg) & Yong Heng Phua (OIST) 📅 1 July 9AM CEST 🔗 tinyurl.com/4mjaverj Spread the word! @protistwtmostest.bsky.social @ehehenberger.bsky.social @chandnibhickta.bsky.social&Norico Yamada

Share with your network, group members, colleagues & friends. We are extending the deadline till the 10th of June. This is your last chance of joining us this summer. #Science #ProtistsOnSky #Cell #Biology #Microscopy

Very excited that our work describing hu.MAP3.0 is published in @molsystbiol.org. Here we use machine learning to integrate >25k mass spectrometry experiments to place ~70% of human proteins into 15k protein complexes. www.embopress.org/doi/full/10....

Great dinner with our cryoET friends from Basel! @sofie-dot-rec.bsky.social @computingcaitie.bsky.social @cellarchlab.com @jacky and Mohamad Harastani

🌱 Excited to share that I will start my lab at EPFL, CH this June supported by a @snsf.ch Starting Grant! ramakrishna.ch We are interested in plant mineral nutrition and will deep-dive into the fine-tuned mechanisms employed by plants to adapt to abiotic stresses such as salinity. #newPI #plantsci

What a fantastic day of science at FCBIS! @friedlab.bsky.social and I had a blast co-organizing this exciting dive into the chemistry-biology interface—great conversations, amazing energy, and a standout keynote by @edwardmarcotte.bsky.social. Thanks to all who joined us!

I'm super happy that our story is now published! 📖 www.science.org/doi/10.1126/... But what changed compared to the original preprint? Also, I feel i should post Movie 1 🎥, that inspired the cover. Back when I did the original bluesky thread, movies were not available.

The final version of our work on the in-cell architecture of the mitochondrial respiratory chain is now online in @science.org 🎉 You can find the full story here www.science.org/doi/10.1126/... @verenaresch.bsky.social did a wonderful job on the cover and animation, she really brought it to life 👩‍🎨

Excited to announce the 10th "Choanoflagellates & Friends Workshop" over May 20-22 in our own Institut Pasteur in Paris: 2025choanocon.wordpress.com Registrations open til March 15, abstract til March 5. Pre-conference event for students/postdocs on 19/05. Plenty of slots for selected talks/posters!

We (@cellarchlab.com peeps, @manondemulder.bsky.social @phaips.vd.st @fannyleblanc.bsky.social @computingcaitie.bsky.social and Ricardo) had a blast at the EMBO in situ meeting in Heidelberg! Meeting old friends and making new ones! Lots of cool science and new ideas to try 👨🏻‍🔬🔬

Excited to share our ✨preprint✨ from my work in Ted Wensel's lab! We present novel insights into the photoreceptor-specific roles of CEP290. 🧵👇 Thanks for the helpful participation from everyone involved, especially @mrobichaux.bsky.social and @agostolab.bsky.social! www.biorxiv.org/content/10.1...

Most plants can`t handle salt, but have evolved strategies to survive in it. How do they do it?🌱🧪 Excited to share some of our first insights using a new cryoelemental imaging technique to answer these questions at the subcellular scale!(1/8) www.nature.com/articles/s41... @nature.com #PlantScience

Proud to share our work spear-headed by PhD student Tommy Sroka with major contributions by #xenopus expert Kerstin Feistel. Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.