More Iterative expansion for a specific inner mitochondrial membrane protein

Iterative expansion microscopy for protein on the mitochondria inner membrane

Great Cormorant, Preverenges Switzerland. Go birds

Happy Physio!

Go Physio!!!

Happy Physio!

New tattoo: Cajal‘s microscope. His illustrations of cortical neurons, hippocampal neurons, synapses, and the brain. Shout out to Phil from the tattoo Lab for his brilliant work

Cristae

Mitochondria!

Phase! Contrast!

Just testing out DIC on my cheek cells for a writing break

Happy Expansion Microscopy Day at Quantitative Imaging @qiatcshl.bsky.social

Our latest preprint www.biorxiv.org/content/10.1..., describes Willi Stepp’s project to make smart microscopy even gentler by doing event detection in phase contrast. We developed neural networks to detect mito-LD and mito-lysosome contacts, as well as mitochondrial pre-fission constrictions.

@fedegasparoli.bsky.social science! @qiatcshl.bsky.social

Great imaging today at Quantitative Imaging at CSHL @qiatcshl.bsky.social #expansion

Expansion microscopy of a tardigrade

Demonstrating how local environment impacts fluorescence 🔬🧪🥼@qiatcshl.bsky.social

The final version of our work on the in-cell architecture of the mitochondrial respiratory chain is now online in @science.org 🎉 You can find the full story here www.science.org/doi/10.1126/... @verenaresch.bsky.social did a wonderful job on the cover and animation, she really brought it to life 👩‍🎨

If you are looking to do GPU deconvolution in Fiji checkout the new updates to CLIJ (OpenCL for ImageJ) deconvolution. @nkiaru.bsky.social has done updates to the tiled deconvolution and integrated with BigDataViewer, and I've added a new script for batch processing. forum.image.sc/t/clij-openc...

@science.org A subcellular map of translational machinery composition and regulation at the single-molecule level | Science www.science.org/doi/10.1126/...

Fluorescence Freitag!

Tardigrade

Tardigrades and Rotifers

Great place for microscopy

I'm so happy to share our work discussing nucleoid trafficking inside the mitochondrion and mitochondrial network, led by the amazing @jmacuada.bsky.social Available in @cp-trendscellbio.bsky.social www.cell.com/trends/cell-... #mito #mitochondria

The magic of the live #mito straight from the microscope 🔬 for #FluorescenceFriday - brought to you by #SYBRgold 🟢 and #PKMO 🟠 @spirochrome.com @carolinklose.bsky.social @lycasworks.bsky.social

Awesome modelling by @askeejdrup.bsky.social !! Great Investigation to links between dopamine dynamics and DAT nanodomains!!! In @elife.bsky.social: Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum doi.org/10.7554/eLif...

🥼 New research from the Lippincott-Schwartz Lab reveals a novel mechanism for signal transmission in brain cells & helps answer an open question in neuroscience about how intracellular signals travel over long distances in neurons.

Just chillin

Lifetime microscopy is just a phase

Rockin’ out at EMBO in situ with @lycasworks.bsky.social @jonasries.bsky.social Christian Zimmerli, Mark Bates 🤘🔬

Time to show the datas

New preprint from the lab! 🚨 🧫 New galactose #CRISPR screening strategy 🎯 481 genes required for #OXPHOS ⚙️ #FAM136A in IMS proteostasis 👂Mito defects in #Menieres disease by @marcellharhai.bsky.social @fbm-unil.bsky.social A short thread 1/5 www.biorxiv.org/content/10.1...

🗣️ Physiologists, rejoice! Thought you missed the deadline for the 2025 Physiology course at MBL? Don't toss out that application draft—you can now apply through February 3. Read more: bit.ly/3BZSj9c #ScienceStartsHere

Nuclear pores

Thank you for the awesome probe, and big shout-out to @lycasworks.bsky.social for the STED wizardry ✨

Gels gels gels

Applications for our Quantitative Imaging: From Acquisition to Analysis 2025 course (Mar 24-Apr 8) are due on Jan 31! Come immerse yourself in microscopy and image analysis with me, @talleylambert.bsky.social, @bethcimini.bsky.social, @florianjug.bsky.social & Hunter Elliott! Please RT

To meet the flash talk time requirements I’ll just say every third word

4500 frames a minute, 😍

A decade in, expansion microscopy is unlocking insights across biology and medicine https://go.nature.com/4adlNgg

Mitochondria 🥳

New microscope 🚨🚨🚨

Home is where the lab bench is

Dyna-mitochondria

wunderbare Kernporen!

Join me, @talleylambert.bsky.social, @bethcimini.bsky.social, @florianjug.bsky.social & Hunter Elliott for our two week CSHL course on microscopy & image analysis starting March 24, 2025! Applications are due 1/31/25. meetings.cshl.edu/courses.aspx...