Want to up your microscopy and image analysis game? Applications open now for QI 2026! Join us in cold spring harbor for two weeks of intensive training in all things microscopy.

🔬 🖥️ Applications are open for the CSHL course Quantitative Imaging: From Acquisition to Analysis (April 6–21, 2026)! An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools. 🗓️ Apply online by Jan 30, 2026

Turn up the volume! 🥳

One of the most useful resources for anyone who uses fluorescence methods.

The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it! www.fpbase.org/spectra/

Required reading for cell biologists to get a sense of basic statistical principles! www.nature.com/articles/s41...

Registration for Halfway to I2K is now OPEN! And workshop submission is still too (for a bit)! Join 20+ presenters and counting, and hundreds of attendees in learning about image analysis, whether you're a complete beginner or a total pro.

Italian 🇮🇹 scientists! Our open call for image analysis support through the @humantechnopole.bsky.social national facilities is currently accepting applications!

Happy birthday Eva!! @sciencedoodles.bsky.social

This 2009 article by @jencwaters.bsky.social discusses the parameters of digital image acquisition that affect the accuracy & precision of quantitative fluorescence #microscopy measurements rupress.org/jcb/article/... In #Reproducibility & Best Practices in Cell Biology: rupress.org/jcb/collecti...

In 2019, Anna Jost & @jencwaters.bsky.social reviewed best practices for validating quantitative #microscopy methods & discuss strategies to avoid unconscious bias in imaging experiments rupress.org/jcb/article/... 📕 In #Reproducibility & Best Practices in Cell Biology: rupress.org/jcb/collecti...

Production has started for a new #Snoutscope objective, AMS-AGY v3. It has significantly larger FOV and some other tweaks from v1 and v2. Currently accepting pre-orders. The price will need to increase modestly after deliveries start late October.

3rd challenge from AI4Life! We're inviting the community to design unsupervised models that preserve spatial & temporal patterns in neuronal data. 📅 Open till Aug 11, 2025 🚀 Join now: ai4life.eurobioimaging.eu/challenge-3/

This week, we are highlighting Helen Zenner, Community Manager of @focalplane.bsky.social and @jcellsci.bsky.social Online Editor, as an extraordinary biologist. #100biologists @helenzsci.bsky.social

Do you like developing new AI vision methods for microscopy image analysis? You love theory & implementation? 1 week left to apply for a fully funded PhD position in our lab in Dresden 🇩🇪! Topics: object detection/tracking, multimodal models & more. DM/email for details! #PhD #AcademicJobs #GPUsgoBrr

The Surprising Scientists Hit by Trump’s D.E.I. Cuts www.nytimes.com/2025/07/10/u...

New PIs: Objective lens damage during routine use is real. These videos explain how this can happen and how to avoid it. Share with your lab! #savetheobjectives

In Advice: It can feel very risky to tell your doctoral adviser that you plan to deviate from the expected faculty career path. Here’s how to approach that conversation. chroni.cl/4end1P1

The White House's proposed FY26 budget would cut NIH funding by >40%. Our new #SCIMaP report projects the budget would lead to economic losses throughout the US with $10M+ lost in almost every House district. scienceimpacts.org/fy26 @joshuasweitz.bsky.social @asinclair.bsky.social @cl10.bsky.social

"The money the government sends to Harvard is, in effect, not a subsidy to advance the university’s mission. It’s a payment for the role Harvard plays in advancing the research mission of the United States." www.nytimes.com/interactive/...

"Without researchers at Harvard or other universities doing this foundational work, it’s not clear who would. The government doesn’t have the expertise. Companies don’t have the luxury of time."

"This is the science model the U.S. has developed over 80 years: The government sets the agenda and funds the work; university scientists design the studies and find the answers... There is no alternative in the U.S. to produce the kind of scientific advancements represented by these grants."

“The money the government sends to Harvard is, in effect, not a subsidy to advance the university’s mission. It’s a payment for the role Harvard plays in advancing the research mission of the United States.” www.nytimes.com/interactive/...

Watching a science talk with slides completely incomprehensible to us colorblind folks. Easily fixable with a little effort… 🧪

"I'm still in shock. I know that there have been political issues around Harvard in recent weeks, but antibiotic resistance isn't one of them." My conversation with Harvard microbiologist @baym.lol, one of many researchers there who just lost millions in fed. grants. www.wbur.org/news/2025/05...

See this? It's called a non-inferiority trial. It compares the new vaccine with the current vaccines to see if the new vaccine does better. This new vaccine did. Placebo-controlled trials are not needed to test most new vaccines. Demanding them will only reduce vaccine access. Which is the point.

Your yearly reminder to acknowledge the core facilities you use and their staff scientists in your papers. These scientists are a crucial part of the scientific ecosystem and to continue to exist they need tangible credit for their work. Plus their associated expertise adds credibility to your work.

The latest AIC Call for Proposals is now open! Deadline is June 16, 2025. Come use @hhmijanelia.bsky.social imaging technology and expertise for FREE. Visit www.aicjanelia.org/apply for details. Before applying, contact us to schedule a technical consultation!

US students. Looking to apply to graduate school? Had an offer rescinded recently? The University of British Columbia in Canada will re-open the application portal in some departments for US students from April 14-18. Details: www.grad.ubc.ca/us-applicant... #ubc #AcademicSky #PhDSky #ScienceSky

Light sheet baby!! QI2025

Our latest preprint www.biorxiv.org/content/10.1..., describes Willi Stepp’s project to make smart microscopy even gentler by doing event detection in phase contrast. We developed neural networks to detect mito-LD and mito-lysosome contacts, as well as mitochondrial pre-fission constrictions.

Our first prize winners for their confocal data presentation: 'Pinhole Pros' Federico & Naly!

Close to the end! #mixedfeelings

Half way there!

I spy with my little eye...a sneak peek of our light sheet microscopy lab samples! Perks of being a @cshlnews.bsky.social course is access to lots of great sample collecting spots! #catchoftheday #tardigrades

Our openSPIM is officially up and running to image the latest catch of the day! Fueled by pymmcore-plus & pymmcore-gui! 💪⚡🔬 pymmcore-plus.github.io/pymmcore-plus/ github.com/pymmcore-plu...

QI 2025 student Federico, a computer scientist, oiling an immersion lens for the first time. 💪

@fedegasparoli.bsky.social is setting up our openSPIM in preparation for the light sheet lab next week. Pro tip: Stouts block light more effectively than lagers.

Full calendar, great students, dedicated instructors & TAs, and nonstop learning! 🔬🖥️ 📊#microscopybootcamp

Excited teach & help w/BoBiAC! This course is perfect for grad students & postdocs using fluorescence microscopy to learn how to use python to process & analyze image data! Best part: it's beginner friendly - no python experience required! More info & apply: iac.hms.harvard.edu/bobiac/2025/...

New Python image processing and analysis course!! Pls retweet

Come learn microscopy with us by the sea in May!

“Join the Pigino Lab! We’re hiring a PhD student to explore primary cilia biology using advanced imaging, spatial ‘omics, and AI. Apply now at www.cilia-ai.eu and be part of the Cilia-AI Doctoral Network!”

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🔬🎤 As pre-announced a few days ago... please let us proudly present to you: 𝑴𝒊𝒄𝒓𝒐𝕊𝒑𝒍𝒊𝒕 - your ticket to imaging more, imaging more gentle, and/or imaging more efficient. 🔬 doi.org/10.1101/2025... Like ❤️, repost 🔂, and most importantly... please send feedback ✉️ our way! 🙏

Every time someone mentions using a #FRET #biosensor to me, I still think about this tweet from @joachimgoedhart.bsky.social. Even after seven long years. #Microscopy #Imaging #CellBiology #PlantMicroscopy