🌍 Cilia2027 | Mar 8–12, 2027 | 📍 Stresa, Lake Maggiore, Italy Join the global cilia community for science, collaboration & discovery (+ fun!!). #Cilia2027 #CiliaBiology

CDKL5 Deficiency Disorder (CDD) leads to seizures & intellectual disability. This study shows that #Chlamydomonas CDKL5 kinase is activated by the LF2/CDK20 kinase; CDKL5 in turn regulates #intraflagellar transport via protein abundance & phosphorylation #cilia @plosbiology.org 🧪 plos.io/45490eP

Very grateful to @carlsbergfondet.dk for supporting our Research Infrastructure application to purchase a new NTA for studying #cilia and #extracellular #vesicles 🙏😀 bsky.app/profile/carl...

🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.

Nice work indeed… among all the interesting findings, quite amazed to see that you can induce the formation of ciliary pockets just by the removal of Arp3! #cilia #ciliopathies #kidney

Dynein-2 prefers to bind the retrograde-targeted A-tubule in intraflagellar transport - likely because of its tyrosination, suggest cryo-ET data and MD simulations by @ichikawa-lab.bsky.social and coworkers www.embopress.org/doi/full/10....

We’re excited for the UK Cilia and Centrosome Network e-symposium this afternoon featuring the #JCSciliaSI! To discover more about the research in this issue, check out these JCS snapshots, video highlights from authors about their research: focalplane.biologists.com/2025/11/24/j...

And we’ll be back for four sessions in 2026- first 14/01/2026! Register: www.eventbrite.co.uk/e/bscb-genso... #UKCilia2025 /9

In the meantime, try a deep dive into our JCS Special Issue on Cilia and Flagella to fully immerse yourself into some great research, fantastic insight and provocative opinions: journals.biologists.com/jcs/issue/13... /fin

Thanks for the shoutout! @jcellsci.bsky.social :)

It was a lot of fun to write this review on cilia proteimics with Bernhard Schermer @cilib.social.cologne.ap.brid.gy and Ronald Ropeman, and we are excited to see it published in the @jcellsci.bsky.social special issue on Cilia and Flagella: from basic Biology to Disease.

Rudolfo Karl, Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social and colleagues discover that renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease. #JCSciliaSI journals.biologists.com/jcs/article/...

Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase. www.nature.com/articles/s41...

While trying to steer clear of the ‘best organelle’ debate, we’re delighted to highlight #JCSciliaSI, guest edited by @cilialab.bsky.social & @lottepedersen.bsky.social. And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!

Akisato Marumo, Hiroto Ishii, Shin Yamaguchi, Junichiro Yajima and colleagues characterise the 3D beating pattern of the ciliary tip in the live ciliate Tetrahymena. #JCSciliaSI journals.biologists.com/jcs/article/... #OpenAccess #ReadandPublish

Registration is now open to attend Journal of Cell Science's meeting on Imaging Cell Dynamics, organised by Francesca Bottanelli, Guillaume Jacquemet, Michael Way and Giulia Zanetti. Find out more: biologists.com/meetings/jcs... #JCSimaging #Microscopy #Microscope #Imaging #Cells #CellScience

Mark Lee @guacamarklee.bsky.social and Keren Hilgendorf @uofubiochem.bsky.social discover that prostaglandin E2 inhibits adipogenesis through the cilia-dependent activation of ROCK2. #JCSciliaSI journals.biologists.com/jcs/article/...

🥳TheRaCil Publications Alert🚨Visit theracil.eu/news-and-pub... - cilia biology & perspectives for AI in nephrology👉KIF13B controls ciliary protein content, Rezi et al @lottepedersen.bsky.social 👉AI for diagnosis and care in rare kidney disease review, Chen et al @knebel.bsky.social #cilia #kidney

Malek Elsayyid, Alexis Semmel, Jessica Tanis and colleagues find that phosphatidylinositol 4,5-bisphosphate impacts extracellular vesicle shedding from C. elegans ciliated sensory neurons. #JCSciliaSI journals.biologists.com/jcs/article/...

Also in Issue 20: - Editorial from Pleasantine Mill @cilialab.bsky.social and Lotte Pedersen @lottepedersen.bsky.social. - 'Cell Scientist to Watch' interviews with Keren Hilgendorf and Girish Ram Mali @dyneinassembly.bsky.social journals.biologists.com/jcs/issue/13... #JCSciliaSI

Exciting news: the new review from @centriolelab.bsky.social is out in the amazing #JCSciliaSI! 🎉 I had the pleasure of working alongside Olivier Mercey, Paul Guichard and Virginie Hamel on this one. Cherry on top: our #UExM image was selected for the cover of the issue! 🤩

We are looking for: PhD Student (starting as Research Assistant) and Postdoctoral Researcher in Stem Cell Biology and Mechanobiology. Please RT💕 🔗 About our lab: renew.science/principal_in... 🎓 PhD position: jobportal.ku.dk/phd/?show=15... 🧪 Postdoc position: jobportal.ku.dk/videnskabeli...

This is our first submission to @jcellsci.bsky.social and the experience was fantastic. We will absolutely be submitting here in the future. Highly recommended.

We are thrilled to see this out in @jcellsci.bsky.social an in the special issue on Cilia. Cfap298 - which we call Kurly - is the mutant that keeps on giving us surprises! In this paper, a mutation generated by CRISPR, that deletes two aa and changes a third, specifically affects cilia motility.

It was a great pleasure working with @cilialab.bsky.social and @seemagrewal.bsky.social plus others at @jcellsci.bsky.social on this special issue on ‘Cilia and flagella’. Lots of cool stuff on #cilia #flagella in there, enjoy!

📣 Here it is — our overview on ciliary proteomics! Great discussions and writing with @mick-lab.bsky.social and Ronald Roepman 🙏🙏 Hope we didn’t miss anything important - apologies if we did! #cilia #ciliopathies #proteomics @theracilproject.bsky.social @for5547.bsky.social tinyurl.com/yc8ztn5v

CiliaQ Editor just received a convenient upgrade allowing to faster inspect and correct segmentations of #cilia in the #CiliaQ workflow (automatic color & BC adjustment, new functions, etc.). If you update FIJI, you automatically update to the new version. All details at github.com/hansenjn/Cil....

Ever wondered what microtubule inner proteins (MIPs) are and what they actually do? Or perhaps you already know about them, but find it hard to keep track of which ones are conserved across species and how they support ciliary structure and function? journals.biologists.com/jcs/article/...

Miao Gui and I wrote a Review for the @jcellsci.bsky.social special issue “Cilia and Flagella: From Basic Biology to Disease”. It provides a comprehensive and up-to-date overview of MIP structure, function, and the latest tools used to study them, crafted to serve both newcomers and experts.

This was a fun chat. Thanks @jcellsci.bsky.social for featuring me and spotlighting our work. Check out the special issue on Cilia and Flagella journals.biologists.com/jcs/issue/13.... We have an article on Axonemal Dynein Assembly Factors (DNAAFs) which may be useful for the field.

I’m excited to share this collaborative work with Prof. Dagmar Wachten (@wachtenlab.bsky.social), providing an accessible overview of primary cilia signalling and recent advances in cellular signaling in health and disease. Many thanks to Dagmar for a fantastic collaboration! doi.org/10.1242/jcs....

Daniel Abbühl, Philippe Bastin @bastinlab.bsky.social and colleagues use a novel approach for tagging tubulin to dissect microtubule assembly dynamics of the axoneme in Trypanosoma brucei. #JCSciliaSI journals.biologists.com/jcs/article/...

What a treat! Thank you @jcellsci.bsky.social

📣 We are moving to Barcelona to join the amazing @crg.eu and explore how centrosomes & cilia work, evolve & respond to the environment. We are looking for PhD students www.crg.eu/en/content/t... Postdocs gimm.pt/jobs/postdoc... Other calls to open, also for an experienced lab manager. Get in touch!

Everything you wanted to know about #cilia & #signaling in one big beautiful poster format from field thought leaders @wachtenlab.bsky.social & @sorentc.bsky.social- from our just live @jcellsci.bsky.social Special Issue… 🤩🤩🤩

Our Special Issue on Cilia and Flagella: from Basic Biology to Disease, guest edited by @cilialab.bsky.social‬ and @lottepedersen.bsky.social, is building. We’ll be highlighting all the articles over the next couple of weeks. Follow along at #JCSciliaSI. journals.biologists.com/jcs/issue/13...

With @jcellsci.bsky.social, we're 🥂 celebrating the Special Issue on Cilia & Flagella, guest edited by myself & @lottepedersen.bsky.social. We've handpicked 4 standout papers – research from our community, for our community – paired with 2 cutting-edge talks showcasing latest breakthroughs. /2

Despite the mess, we are grateful to be funded, have exciting science happening, and have an opening for a postdoc! If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email. Please RT 🙏

Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia. Open access link below: www.nature.com/articles/s41... Here's a cool animated summary

So proud and happy to share that our study on the #proteome, heterogeneity, and cell-type specificity of primary #cilia is published now at Cell 🎉 Big thank you to all the many people that made this possible, at the Lundberg Lab, Human Protein Atlas, Lindstrand lab, and Hsien-Sheu lab.

Am I oddly excited to learn about the tree that @jcellsci.bsky.social protected in the Forest of Biologists in recognition of my peer review? Yes. 🤓 forest.biologists.com/landscape/?i...

We are hiring! We are currently interviewing for an entry level staff position in the lab, but it is not too late to submit a postdoc application! Send a note of interest to me and apply here: bit.ly/3VmmM7m

My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438 @dartmouthbcb.bsky.social @futurepislack.bsky.social

Be our new colleague! 🎉 The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor. 👉 More details here: lnkd.in/e8Z9eAm4 👉 Our department: mocel.unige.ch Please feel free to share this opportunity with your network.

I’m biased 🇩🇰, but this is quite nice to read: I thought science hinged on prestige. Moving abroad made me reassess my priorities www.science.org/content/arti...

The Dunn School PhD programme is live! 🎉 Two projects in our labs: 1) How the motor protein giant dynein-2 works 2) How signalling-essential membrane proteins get into cilia Cryo-EM/ET, single mol & live-cell fluor microscopy, CRISPR-based genetic tools & more! www.path.ox.ac.uk/study-with-u...

The annual Dunn School DPhil studentship competition for 2026 is open for applications. We have a project aimed at understanding the molecular mechanisms of ciliary dynein transport. See details below and please pass on to anyone who might be interested. www.path.ox.ac.uk/project/mech...

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia: Current Biology www.cell.com/current-biol...

Primary #cilia dysfunction as in Bardet-Biedl syndrome compromises normal adipogenic differentiation in favor of fibrogenic transition, predisposing to obesity @wachtenlab.bsky.social and collaborators www.embopress.org/doi/full/10....

New paper on DYRK kinases and primary cilium! This project began with our interest in DYRK3’s relationship to centriolar satellites. But what started as a CS-focused story soon evolved into studying DYRK kinase activity during ciliogenesis. nature.com/articles/s42...