WachtenLab
@wachtenlab.bsky.social
๐ค 505
๐ฅ 1048
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Science and ideas from the lab of Dagmar Wachten
reposted by
WachtenLab
DGZ.bsky.social
2 months ago
The next
#DGZ
Focus Workshop on
#Cilia
&
#Centrosomes
will take place November 25 (end of October is our DGZ meeting in HD). Join us for a great speaker line-up, and big thanks to David Mick
@mick-lab.bsky.social
& Dagmar Wachten
@wachtenlab.bsky.social
for organizing!
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reposted by
WachtenLab
The EMBO Journal
4 months ago
Primary
#cilia
dysfunction as in Bardet-Biedl syndrome compromises normal adipogenic differentiation in favor of fibrogenic transition, predisposing to obesity
@wachtenlab.bsky.social
and collaborators
www.embopress.org/doi/full/10....
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๐จ New in The EMBO Journal! Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cellsโremodeling adipose tissue before obesity begins. ๐ฌ
#BBS
#cilia
@for5547.bsky.social
@sfb1454.bsky.social
@batenergy.bsky.social
๐
www.embopress.org/doi/full/10....
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BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue | The EMBO Journal
imageimageDisruption of ciliogenesis in Bardet-Biedl syndrome (BBS) leads to obesity and disrupted adipogenesis. This study reveals that ciliary dysfunction in a mouse model of BBS induces a a cell fa...
https://www.embopress.org/doi/full/10.1038/s44318-025-00524-y
4 months ago
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reposted by
WachtenLab
Ningaloo Biosystems
5 months ago
๐จ Catching up with great news! Our NAR paper with the
@wachtenlab.bsky.social
and supported by Prof. Mรถglich presents a powerful light-switch for gene expression in mammalian cells, with big potential for bioproduction and research.
#Optogenetics
#SyntheticBiology
#Bioproduction
#GeneExpression
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Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research
Abstract. Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chem
https://academic.oup.com/nar/article/53/12/gkaf546/8178389?login=true
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๐ก Paper alert! We developed DEL-VPR, a potent blue-light photoswitch inducing gene expression in mammalian cells. From basic research to antibody production, this tool offers precise & strong gene control. Teamwork with
#Ningaloo
academic.oup.com/nar/article/...
#SyntheticBiology
#Optogenetics
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Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research
Abstract. Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chem
https://academic.oup.com/nar/article/53/12/gkaf546/8178389?searchresult=1
6 months ago
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reposted by
WachtenLab
Mass Lab
6 months ago
We are SO EXCITED to share our story
@nature.com
: ๐งต1/ Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring. This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease. ๐ Read here:
rdcu.be/erD3b
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Kupffer cell programming by maternal obesity triggers fatty liver disease
Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.
https://rdcu.be/erD3b
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Looking forward to an inspiring 2-day
#iii
institute retreat packed with great science, collaborations, and fresh ideas. Grateful to
@unibonn.bsky.social
for hosting us in
#IMPULSE
! ๐๐ฌ
7 months ago
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Huge congratulations! ๐
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7 months ago
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Thrilled to be part of this amazing journey! ๐ Hurray indeed!
@dfg.de
has just approved funding for ImmunoSensation3 ๐ Focused on Immune Diversity, we're set for 7 more years of cutting-edge
#immunology
in
#Bonn
! Letโs go! ๐ฅ
#ImmunoSensation
#science
add a skeleton here at some point
7 months ago
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Proud PI - congratulations to Seniz for being awarded the "Rising Star" award of the
@for5547.bsky.social
#cilia
add a skeleton here at some point
7 months ago
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reposted by
WachtenLab
FOR5547 Primary cilia dynamics
7 months ago
Grateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: weโve got a new rising star on the team!
#cilia
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๐ Huge congratulations to Susan Dutcher
@dutcherlab.bsky.social
on her election to the National Academy of Sciences! A well-deserved recognition of her outstanding contributions to cell biology and cilia research. ๐๐ฌ
#WomenInSTEM
#Cilia
add a skeleton here at some point
8 months ago
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reposted by
WachtenLab
FOR5547 Primary cilia dynamics
8 months ago
Excited for an inspiring meeting in France ๐ซ๐ท on
#cilia
and
#centrosomes
! The German
#cilia
community is en routeโletโs connect and share science!
add a skeleton here at some point
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reposted by
WachtenLab
Philippe Bastin's Lab
8 months ago
Dear cilia researchers, join us in the heart of the beautiful Vosges mountains to share your latest findings! This year, partnership with
@for5547.bsky.social
and keynote lectures by
@micromotility.bsky.social
and
@mick-lab.bsky.social
Registration is now open
www.cfc2025.conferences-pasteur.org
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Congratulations to Ronja from the
@wachtenlab.bsky.social
, who won the 1st poster prize at the international
@batenergy.bsky.social
meeting! ๐๐ฅณ
9 months ago
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reposted by
WachtenLab
Nathalie Jurisch-Yaksi
10 months ago
Cilia has been at the center of our discussions at the spring school of our
@for5547.bsky.social
cilia consortium. In total there were 26 trainees from across Europe, few PIs and our brilliant coordinator Christina Klausen.
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reposted by
WachtenLab
David Mick
10 months ago
Interested in primary
#cilia
,
#microtubules
,
#protein
trafficking, molecular
#signaling
,
#GPCRs
, and
#ciliopathies
? We are looking for a
#postdoc
and a
#PhDstudent
to apply advanced
#biochemistry
and
#proteomics
methods to study cilia. Check out our website and send your application until March 10.
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Thanks a lot to
#FEBS
and the Norwegian bioscience society for hosting me and special thanks to
@nathaliejuya.bsky.social
and
@emreyaksi.bsky.social
for your hospitality!
add a skeleton here at some point
11 months ago
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Looking forward to
#Cilia
2027 - watch out for more information!
add a skeleton here at some point
11 months ago
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reposted by
WachtenLab
TRR333 BATEnergy
11 months ago
We would like to welcome you to our second International Conference on Brown and Beige Fat March 31st - April 02nd 2025 Top-class speakers, cutting edge research and respected experts will come together in beautiful Bonn. Registration is open!
www.trr333.uni-bonn.de/batenergy-sy...
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reposted by
WachtenLab
IRB Barcelona
11 months ago
๐ฃ๏ธWe are
#hiring
! Check out our the latest job opportunities! โซ๏ธ Personnel Administration Expert ๐ Due date: 17/01/2025 โซ๏ธ Flow Cytometry Technician ๐ Due date: 19/01/2025 โซ๏ธ Postdoctoral Fellow in Innate Immune Biology (Dr. Stefanie Wculek) ๐ Due date: 28/02/2025 โก๏ธ
bit.ly/3MR4wO8
๐งช
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reposted by
WachtenLab
FOR5547 Primary cilia dynamics
11 months ago
Fantastic team work by our
@for5547.bsky.social
PIs, headed by David Mick! Check this out:
www.biorxiv.org/content/10.1...
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iAPEX: Improved APEX-based proximity labeling for subcellular proteomics using an enzymatic reaction cascade
Ascorbate peroxidase (APEX) is a versatile labeling enzyme used for live-cell proteomics at high spatial and temporal resolution. However, toxicity of its substrate hydrogen peroxide and background la...
https://www.biorxiv.org/content/10.1101/2025.01.10.632381v1
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reposted by
WachtenLab
Mill_lab
12 months ago
Calendars out- just over two weeks until our ๐50th๐ฅณ
@bscb-official.bsky.social
@gensocuk.bsky.social
@ukcilianetwork.bsky.social
e-symposium 14/01/2025 15:00-17:30- everything hot in
#cilia
#centrosomes
free & open to all! Register to access this ๐ฅ series:
www.eventbrite.co.uk/e/bscb-genso...
/1
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Congratulations to Elvira and the whole team!!
add a skeleton here at some point
about 1 year ago
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Come and visit our
#healthybition
at
#museumkoenig
in Bonn! Thanks a lot to everyone who made this possible!
@dfgpublic.bsky.social
#unibonn
#unistiftung
and many more!
add a skeleton here at some point
about 1 year ago
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reposted by
WachtenLab
FOR5547 Primary cilia dynamics
about 1 year ago
Many happy faces in our teaching series about
#cilia
dynamics, connecting the next generation of
#cilia
researchers within our
@for5547.bsky.social
and beyond! Thanks a lot,
@nathaliejuya.bsky.social
for taking the lead!
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reposted by
WachtenLab
Cluster of Excellence ImmunoSensation
about 1 year ago
๐จ Apply now for the ImmunoSensation Postdoc Innovation Funds! We are excited to invite early-career postdocs from the Cluster to apply for funding of up to โฌ10,000 for a 12-month period. The funding period begins on February 1, 2025. Application Deadline: January 10, 2025
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Great team effort guys!
@wachtenlab.bsky.social
@labwilhelm.bsky.social
Andreas Schlitzer and all PIs in our
@sfb1454.bsky.social
add a skeleton here at some point
about 1 year ago
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reposted by
WachtenLab
Simon Cook
about 1 year ago
Come and join
@babrahaminst.bsky.social
Tenure-track and tenured group leader positions in the Immunology Programme
babrahaminstitute.livevacancies.co.uk#/job/details...
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hireful.
https://babrahaminstitute.livevacancies.co.uk/#/job/details/477?target=frame
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reposted by
WachtenLab
Nathalie Jurisch-Yaksi
about 1 year ago
Follow the latest findings from our German consortium on cilia dynamics, now on Bluesky
@for5547.bsky.social
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