Mass Lab
@masslab.bsky.social
📤 793
📥 666
📝 55
Based @LIMES Institute @University of Bonn, researching developmental immunology. We ❤️ macrophages!
pinned post!
We are SO EXCITED to share our story
@nature.com
: 🧵1/ Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring. This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease. 👉 Read here:
rdcu.be/erD3b
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Kupffer cell programming by maternal obesity triggers fatty liver disease
Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.
https://rdcu.be/erD3b
6 months ago
2
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reposted by
Mass Lab
Immunology Podcast
2 days ago
Congratulations to Drs. Jose Villadangos and Hamish McWilliam's (
@hay-mish.bsky.social
) labs on their
@science.org
paper! Their teams at the Doherty Institute showed that
#macrophages
are key for MR1 antigen presentation and MAIT cell immunity. 🗒️
https://bit.ly/49W1GW1
🎤
https://bit.ly/44Ay1OG
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reposted by
Mass Lab
Michael Wagner
10 days ago
🚨 Postdoctoral Opportunity for Female Scientists🚨 The University of Vienna is awarding at least 20 fully funded 4 year postdoctoral positions to outstanding female scientists Interested? Get in touch via direct message
careers.univie.ac.at/en/postdoc/e...
#MicroSky
🧪
#PostDoc
@univie.ac.at
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🧬🍽️ Your macrophages may be carrying your mother’s metabolic history! In our
@cp-trendsimmuno.bsky.social
article, we discuss how maternal diet programs lifelong immune function.
authors.elsevier.com/sd/article/S...
#ImmuneMemory
#Macrophages
#MaternalNutrition
#DOHaD
#EarlyLifeProgramming
22 days ago
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reposted by
Mass Lab
Hao Huang
23 days ago
Fresh from Elvira Mass Lab
@masslab.bsky.social
. We are happy to share our thoughts on how maternal malnutrition can shape the development of offspring tissue-resident macrophages during early development. Happy reading!
add a skeleton here at some point
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reposted by
Mass Lab
Journal of Experimental Medicine
about 1 month ago
#Microglia
and CD8⁺ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15. From Frolov,
@haohuang0086.bsky.social
, Stumm,
@masslab.bsky.social
, Beyer et al.:
rupress.org/jem/article/...
📘 In our
#Neuroscience
collection:
rupress.org/jem/collecti...
#SfN25
0
5
1
Happy to have contributed to this beautiful story on
#macrophage
#development
in mice and in
#iPSC
derived cells.
www.science.org/doi/10.1126/...
Big congrats to first author Tomi Lazarov for this massive work!!!!👏
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Characterization of the mammalian prodefinitive angio-hematopoietic lineage
The identification of mammalian prodefinitive angio-hematopoietic progenitors clarifies early hematopoiesis and macrophage development.
https://www.science.org/doi/10.1126/sciimmunol.adt6616
about 2 months ago
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Interested in
#macrophages
? Don't forget the check out this Seminar Series 👇
add a skeleton here at some point
3 months ago
0
5
1
reposted by
Mass Lab
Julius Brennecke
3 months ago
The Vienna BioCenter PhD Program application deadline is approaching: October 10! Join one of Europe’s premier life science campuses, home to cutting-edge research across all areas of biology. Apply and start your scientific journey in Vienna!
training.vbc.ac.at/phd-program/
#PhD
#LifeSciences
add a skeleton here at some point
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reposted by
Mass Lab
Emmanuel Saliba
4 months ago
🔔PhD position open. Interested in building competencies in computational biology in spatial transcriptomics? Malte Luecken's lab and I have an open PhD position, part of the Munich School of Data Science. Application deadline: Sept 26 Link:
www.mu-ds.de
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MUDS - Helmholtz Information & Data Science Academy
https://www.mu-ds.de/
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reposted by
Mass Lab
Maria Viola
3 months ago
Had the wonderful opportunity to present our data on the effect of microplastics on macrophages at
#EMDS2025
! Such a beautiful venue 🤩
@masslab.bsky.social
add a skeleton here at some point
0
23
3
reposted by
Mass Lab
BonnBrain Conference
4 months ago
Application is open! Come join us and our fantastic line-up of speakers next year in March in Bonn!
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reposted by
Mass Lab
WachtenLab
4 months ago
🚨 New in The EMBO Journal! Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins. 🔬
#BBS
#cilia
@for5547.bsky.social
@sfb1454.bsky.social
@batenergy.bsky.social
📄
www.embopress.org/doi/full/10....
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BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue | The EMBO Journal
imageimageDisruption of ciliogenesis in Bardet-Biedl syndrome (BBS) leads to obesity and disrupted adipogenesis. This study reveals that ciliary dysfunction in a mouse model of BBS induces a a cell fa...
https://www.embopress.org/doi/full/10.1038/s44318-025-00524-y
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20
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reposted by
Mass Lab
Marc Dionne
4 months ago
Come be my colleague! We have three open positions at the Assistant/Associate Professor level for candidates in all areas of the biological sciences.
www.imperial.ac.uk/jobs/search-...
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Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
https://www.imperial.ac.uk/jobs/search-jobs/description/index.php?nPostingId=15801&nPostingTargetId=25192&id=PMMFK026203F3VBQB8NLOV4CQ&LG=UK&languageSelect=UK&mask=ext
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25
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reposted by
Mass Lab
Journal of Experimental Medicine
5 months ago
#WomenInSTEM
becoming independent: People should feel free to be themselves and do great science. We asked ten women researchers about their science and the process of setting up a lab as an independent researcher:
rupress.org/jem/article/...
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reposted by
Mass Lab
Michael Silverman
5 months ago
Out today!
www.science.org/doi/10.1126/...
From
@kknoop.bsky.social
& myself on early life immune development & the beautiful publication from Megan Koch & M Shenoy
www.science.org/doi/10.1126/...
Take home message: timing of early life exposures, milk IgG here, is critical for immune development.
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Setting the table for immune tolerance
Interaction between breast milk antibodies and gut microbes shape immune responses during weaning
https://www.science.org/doi/10.1126/science.adz8687
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4
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reposted by
Mass Lab
Seth Thomas Scanlon
5 months ago
This week's
@science.org
#IMMUNOLOGY-themed
SPECIAL ISSUE features Reviews by {Kassiotis & Stoye}, {Nahrendorf, Ginhoux, & Swirski}, {Sharma, Gibbons, & Saphire}, & {@jessmetcalf.bsky.social,
@grahammunology.bsky.social
, Yates, & Cummings} + an absolutely wild & wonderful cover!
scim.ag/3UqRrA6
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reposted by
Mass Lab
Sergiu P. Pasca
5 months ago
Our recent overview of human stem cell models for studying neuropsychiatric disorders (including their limitations and future directions) is now openly available
@annualreviews.bsky.social
of Neuroscience With the great
@rebeccalevymdphd.bsky.social
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🧠 New book chapter out! We review the developmental origin and functional diversity of
#microglia
- key players at the crossroads of
#immunity
and
#neurodevelopment
. 🔹 Ontogeny & specialization 🔹 Transcriptional & metabolic shifts 🔹 Roles in disease & repair 👉
authors.elsevier.com/a/1lKxcErwXf...
add a skeleton here at some point
5 months ago
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1/ 💡We are excited to share our latest paper, continuing our exploration of how maternal obesity programs offspring health via
#macrophages
- this time using
#Drosophila
as a model:
shorturl.at/28tFo
#MaternalObesity
#Drosophila
#Neurodegeneration
#DOHaD
#FlyResearch
#MacrophageBiology
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Developmental programming by maternal obesity alters offspring lifespan and immune responses in a diet- and sex-specific manner
Maternal obesity is a growing health concern that predisposes offspring to metabolic dysfunction, immune system alterations, and neurodegenerative dis…
https://shorturl.at/28tFo
5 months ago
2
5
3
reposted by
Mass Lab
Iannacone Lab
6 months ago
1/ 🚨 Hot off the press in Nature Immunology: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity.
www.nature.com/articles/s41...
🧵(1/11)
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reposted by
Mass Lab
Pallett Lab UCL
6 months ago
The fantastic Menon Lab (
@madhvimenon.bsky.social
) in the
@lydiabeckeriii.bsky.social
in Manchester are hiring!! 🚨DO NOT MISS YOUR CHANCE TO APPLY!🚨
www.jobs.manchester.ac.uk/Job/JobDetai...
Postdoc seeking to unravel how lung-infiltrating
#Bcells
contribute to chronic lung disease
#immunosky
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Research Associate in Mucosal Immunology :Manchester
https://www.jobs.manchester.ac.uk/Job/JobDetail?isPreview=Yes&jobid=31370&advert=external
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reposted by
Mass Lab
Dr. Anusha Seneviratne
6 months ago
🧪 One month until the application deadline. Get in touch if you are interested ⬇️
#immunosky
#cardiosky
#academicsky
#ecr
#studyintheuk
add a skeleton here at some point
1
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3
We are SO EXCITED to share our story
@nature.com
: 🧵1/ Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring. This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease. 👉 Read here:
rdcu.be/erD3b
loading . . .
Kupffer cell programming by maternal obesity triggers fatty liver disease
Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.
https://rdcu.be/erD3b
6 months ago
2
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reposted by
Mass Lab
FOR5775 MagNet
7 months ago
It's time for our next
#MagNet
#Seminar
! It's all about
#KupfferCells
and
#KetogenicDiet
presented by Gerasimos Anagnostopoulos via
#Zoom
⏰ Monday, June 16th, 4 pm Visit our homepage for more infos:
macrophagenetwork.com/magnet-semin...
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The
#Rosshart
Lab goes wild again! Ever wondered whether using
#Wildlings
in our research would change the outcome of our results? 🤔💡
#immunosky
@fau.de
www.nature.com/articles/s41...
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Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype - Nature Communications
Here, the authors apply a standardized system, called TXsystem, to transplant wild mouse gut microbiota into SPF mice, developing “TXwildlings” mice that stably retain natural microbiota and human-lik...
https://www.nature.com/articles/s41467-025-60554-2
7 months ago
0
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5
Super happy to be part of this initiative! Together with
@agvazquez.bsky.social
we will be working on the interaction between
#Alveolar
#Macrophages
and
#Epithelial
#Cells
in the
#lung
Still time left to apply!!
www.linkedin.com/posts/elvira...
#immunosky
add a skeleton here at some point
7 months ago
0
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reposted by
Mass Lab
BonnBrain Conference
7 months ago
Meet our invited speakers!
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reposted by
Mass Lab
Sparwasser Lab
7 months ago
Special issue Immunometabolism and Beyond: from Liver to Brain! European Journal of Immunology Article types: reviews and research articles Submission deadline 1 November 2025 Thanks to Nadja, Matteo and Bin for this wonderful opportunity!
#immunometabolism
#EJI
#CRC1292
#CRC355
#CRC156
#FZI
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Happy to be part of this initiative! The place to be in Germany for
#immunologists
!!! 😎
add a skeleton here at some point
7 months ago
0
8
1
reposted by
Mass Lab
Universität Bonn
7 months ago
We are excellent! What a day - between hugs, applause and a lot of pride. Our rector? Jumping for joy. Our team? Overjoyed. Thank you to everyone who made this historic moment possible!
@dependencybonn.de
@immunosens.bsky.social
@econtribute.bsky.social
© V. Lannert/G. Hübl/Uni Bonn
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reposted by
Mass Lab
FOR5547 Primary cilia dynamics
8 months ago
Grateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: we’ve got a new rising star on the team!
#cilia
0
7
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reposted by
Mass Lab
Rafeeque Mavoor
8 months ago
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!
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reposted by
Mass Lab
Dr Róisín McManus
8 months ago
📢 We are
#hiring
a
#PhD
student to work on an interdisciplinary, collaborative project
@dzne.science
in Bonn, Germany! 🧠 If you’re interested in western diet-induced
#neuroinflammation
and innate immune signalling in
#alzheimersdisease
, check out our ad below 👇
jobs.dzne.de/en/jobs/1014...
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PhD student (f/m/x) in the field of Neuroimmunology 1439/2025/5]
https://jobs.dzne.de/en/jobs/101480/phd-student-fmx-in-the-field-of-neuroimmunology-143920255
1
12
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Just presented our story on
#KupfferCells
#liver
&
#microplastics
togehter with
@mariafviola.bsky.social
in the basic science session @
#EASL2025
in
#Amsterdam
. Great format to promote ECRs and for fantastic discussions with scientists and clinicians!
8 months ago
0
9
2
reposted by
Mass Lab
Journal of Experimental Medicine
8 months ago
#Microglia
and CD8⁺ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15, say Aleksej Frolov, Hao Huang (
@haohuang0086.bsky.social
), Ralf Stumm, Elvira Mass (
@masslab.bsky.social
) Marc Beyer
@dzne.science
and colleagues:
rupress.org/jem/article/...
#omics
#RareDisease
1
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Read our newest publication
@jem.org
about
#microglia
and
#CD8Tcell
interactions in spastic paraplegia! 💡Immune activation happens before
#neuronal
loss! 💡 Team effort with the labs of Marc Beyer and Ralf Stumm 👇
doi.org/10.1084/jem....
@limes-bonn.bsky.social
@immunosens.bsky.social
#immunosky
8 months ago
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Kati Mauel from our lab talking about splenic
#macrophages
and their response to
#malaria
infection at
#EPW2025
🤩
add a skeleton here at some point
9 months ago
0
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Thanks to the organizers
@sancholab.bsky.social
@casanova-acebes.bsky.social
& Carlos Silvestre for giving me the opportunity to kick-off this fantastic meeting
#EPW2025
What a day for
#macrophage
lovers!
add a skeleton here at some point
9 months ago
0
13
3
reposted by
Mass Lab
David Sancho
9 months ago
#immunosky
#epw2025
Great novel work by
@masslab.bsky.social
on the impact of micro and nanoplastics in macrophages! Large effect on liver Kupffer cells, while other organs are more protected. Read more here!!!
sciety.org/articles/act...
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1/ 🚨 New preprint alert! 🚨 Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇
www.researchsquare.com/article/rs-6...
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Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism
Plastic pollution is an emerging yet understudied environmental risk to the immune system. Once ingested, nano- and microplastic particles (MNPs) can translocate from the gut to internal organs, with ...
https://www.researchsquare.com/article/rs-6204281/v1
10 months ago
3
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We are thrilled to present our new story on
#neonatal
#liver
#macrophages
and how they crosstalk with
#hepatocytes
during this early stage of life 👇
add a skeleton here at some point
10 months ago
0
5
1
reposted by
Mass Lab
Dr Laura McCulloch
10 months ago
First Post on blue-sky. We are hiring! Post-doctoral position available in the neuroimmunology of stroke. Please check out link below and share
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
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reposted by
Mass Lab
Oliver Cornely
10 months ago
Joint seminar by
#DGfI
Young Immunologists & Junge
#GfV
! 🎤 Topic: Preclinical & clinical development of novel anti-viral vaccines 🗓 Feb 24, 2025, 17:00 Register here!
us06web.zoom.us/meeting/regi...
#Immunology
#VaccineResearch
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reposted by
Mass Lab
Ivan Zanoni
11 months ago
#WeekendRead
.
#LiveForever
. Lantz, Thorp &co show
@cp-immunity.bsky.social
that in neonatal, not adult, macrophages efferocytosis following heart injury leads to the production of throboxane, that acts on cardiomyocytes promoting proliferation & repair.
#ScienceSavesLives
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Early-age efferocytosis directs macrophage arachidonic acid metabolism for tissue regeneration
Mechanisms that differentiate the capacity of newborn immune cells to orchestrate tissue regeneration are inadequately understood. Lantz et al. discover that in response to dying cells, neonatal macro...
https://www.cell.com/immunity/abstract/S1074-7613(24)00533-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1074761324005338%3Fshowall%3Dtrue
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23
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reposted by
Mass Lab
German Stem Cell Network GSCN
11 months ago
Save the date for the GSCN
#Conference
on
#stemcell
#research
and
#translation
in
#Munich
at
@www.helmholtz-munich.de
from 15 - 17 Oct 2025. Registration is open
gscn-conferences.org/gscn-confere...
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reposted by
Mass Lab
Maria Viola
11 months ago
Could bacterial translocation during colitis rewire the bone marrow? Check out our highlight of these cool findings by the Sancho lab ⬇️
authors.elsevier.com/a/1kbBf3qNrU..
.
@masslab.bsky.social
1
9
4
"Bacterial translocation promotes
#trained
#immunity
" !!! 🤩 Check out our preview highlighting the beautiful peace
@cp-immunity.bsky.social
by the Sanches lab. With
@mariafviola.bsky.social
#macrophages
#Mincle
authors.elsevier.com/a/1kbBf3qNrU...
11 months ago
1
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Happy to have inspired our colleagues to study
#hematopoiesis
#yolksac
=) Congrats to
@wkolanus.bsky.social
for this beautiful
#developmental
study!
add a skeleton here at some point
11 months ago
0
3
0
reposted by
Mass Lab
Dr Róisín McManus
11 months ago
Delighted to start the new funding period of our
#SFB1454
! Can definitely recommend the exhibition @museumkoening, a must for everyone interested in healthy living and aging
@dzne.science
add a skeleton here at some point
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Application deadline extended to February 2nd!
#PhD
#macrophages
add a skeleton here at some point
11 months ago
0
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2
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