#WeekendRead! #NeutrophilPower! @drusqui.bsky.social Aroca &co show @jem.org that neutrophil intrinsic circadian clock can be exploited by targeting CXCR4 to decrease vascular & myocardial damage by relocating neutrophils within the wound core, thus sparing injury to healthy neighboring cells!

New work by @ursmoerbe.bsky.social et al. provides an important framework for understanding gut-associated lymphoid tissues (GALT) diversity and function. rupress.org/jem/article/... 🎥 See a short video summary by Mörbe: youtu.be/iIWKSSnwFTg

As 2025 is drawing to a close, @jem.org would like to highlight all of the women who have contributed to the #WomenInSTEM #Viewpoint series over the last 3 years! Learn more about their scientific journeys on the path to independence here 👉 tinyurl.com/2wrxk4mk

Happy to highlight an essay I wrote together with @marcdemanuel.bsky.social, @natanaels.bsky.social and Anastasia Stolyarova, trying to think through what sets the mutation rate of a cell type in an animal species: www.biorxiv.org/content/10.6... 1/n

#JEMLegacy @jem.org goes back to 1930 with the first description by William Tillett and Thomas Francis Jr. of C-reactive protein (CRP) in the sera of patients during the acute phase of pneumococcal pneumonia. @RockUPress @RockefellerUniv rupress.org/jem/article/...

Today’s #JEMjc @jem.org highlights the work of Alan Saltiel & colleagues @nature.com reporting the role of neutrophil-derived IL-1β in preserving lipid stores during metabolic stress. www.nature.com/articles/s41...

In 6 of 14 patients receiving immune checkpoint inhibitors, cell-free DNA methylation profiling revealed multiorgan damage with immune-related adverse events, often before symptoms appeared. @nejm.org www.nejm.org/doi/full/10....

Download our large database of postdoc fellowships in all fields of research. Database freely available to all; 281 fellowships. Download here: research.jhu.edu/rdt/funding-...

“The collective” 

Spaceflight alters the immune regulatory functions of neutrophil granulocytes on T lymphocytes @cp-iscience.bsky.social www.cell.com/iscience/ful...

🧬🍽️ Your macrophages may be carrying your mother’s metabolic history! In our @cp-trendsimmuno.bsky.social article, we discuss how maternal diet programs lifelong immune function. authors.elsevier.com/sd/article/S... #ImmuneMemory #Macrophages #MaternalNutrition #DOHaD #EarlyLifeProgramming

Could not like this topic better guys! Looking forward to read it! Disclaimer: i ate so much pistacchio ice-cream during my pregnancies 🥹🥲, poor baby TRMs!

Calling all lung immunology enthusiasts 🫁 I’m excited to share this project where we designed and optimised a spectral cytometry platform to study immune responses in the mouse lung at steady-state and during viral infection. We hope this will be a useful resource for the field! Link below 👇

"If we ruin the earth, there is no place else to go” ― Carl Sagan

Feel better during the day than at night during #influenza? Find out the “Role of IL-10 signaling in the #circadian control of host response to influenza infection” www.mucosalimmunology.org/article/S193...

Do not miss this seminar, Roger is great!

Today, we see the fruit of 5+ years of teamwork. We have built a map of the neutrophil compartment (mostly in mice - but also humans). It provides a biological structure that focuses on a single immune cell lineage to discover the many ways in which neutrophils "interpret" physiology.

The NIH grant cuts in 2025 www.nytimes.com/interactive/...

ERC applicants who made the shortlist and got invited to Brussels for an interview

Key points on the need for continued animal use in scientific research. www.theguardian.com/science/2025...

Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair in this work from @lizihegarty.bsky.social, @bainlab.bsky.social, and colleagues: www.mucosalimmunology.org/article/S193...

#PorLaCiencia que hacemos en @cniostopcancer.bsky.social

Climate change poses multiple challenges to our health. Our new article coauthored with @kathelse.bsky.social considers the rise in infections and pollution combines with the impact of climate change on our immune system and what we need to do to better understand this 🧪 🧵#EcoImmunology

Ms4a7 expression in cDC1s determines cross-presentation and antitumor immunity www.science.org/doi/10.1126/... @science.org

We have written two reviews providing a practical guide and fundamentals of cell migration: (1) How to select an optimal cell migration assay, (2) How to analyze cell migration data. We also added a perspective on AI methods of analysis. Coming out soon in Nature Methods.

Now online in Cancer Discovery @aacrjournals.bsky.social: A Prognostic Signature for Lung Adenocarcinoma in Patients Who Have Never Smoked - by Wei Zhao, Maria Teresa Landi, and colleagues doi.org/10.1158/2159...

Using #LLMs for science👨‍💻💬? We have a fun tool for you: introducing #folder2md4llms. It converts an entire folder of docs/code/pdfs/pptx into a single markdown file that you can upload to your chatbot of choice. We use it to talk with our publications database or code repos github.com/HenriquesLab...

NEW Perspective by @alazozcan.bsky.social, Tommaso Vicanolo, Veronique Angeli, Yuval Rinkevich & @drusqui.bsky.social presents a model of immune cells as architects of tissue barriers, by depositing matrix components or by interactions with structural cells and the ECM #structuralimmunity #immunosky

This is what democracy looks like. #NoKings

Many thanks to #AmyGladstein & #DavidFeldser for this great perspective on our recent paper @natcancer.nature.com. As they say in it (and have elegantly shown in their work): "‘Flip the switch’ and let nature show you the way!" 🔦🧬🐭 www.nature.com/articles/s43...

University administration: "We need you to complete 26 hours of lab safety training 🧪 each year so that everyone is safe and responsible." Also university administration:

🧪🧬🔬🔭🥼🌎

'All three awards (...) honored achievements rooted in fundamental research from decades ago. Some experts interpret the selections by the Royal Swedish Academy of Sciences as representing the importance of slow, basic science, work pursued out of a desire to better understand the world.'

The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍

#Macrophages are presumed to attack antibody-opsonized #cancer cells by #phagocytosis. In @jcb.org, @kirstin-rollins.bsky.social, @mmorrissey.bsky.social et al find that macrophages attack adherent cells using #trogocytosis, or cell nibbling, instead of phagocytosis. rupress.org/jcb/article/...

Now online in Cancer Discovery @aacrjournals.bsky.social: Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-Related Patterns and Relies on IL1RAP for Clonal Expansion doi.org/10.1158/2159...

Evidence-based tips on getting better sleep: the primacy of circadian rhythm new feature @nature.com nature.com/articles/d41...

Out now in #Science #Immunology: Zhenghai Tang (U of Macau) & André Veillette (@ircm.bsky.social / @mcgill.ca / @umontreal.ca) review the latest research on inhibitory #ImmuneCheckpoints in #cancer #immunotherapy. Check it out!

⚠️ Half of commercial antibodies miss their target! So how do you pick the right one for your experiment? Here’s the solution 👉 Antibody characterization data (all tested in KO cells) are now available at: 🔗 onlygoodantibodies.co.uk Tested by @ycharos.bsky.social & @oga-community.bsky.social

Our new workflow maps whole human fallopian tubes at single-cell resolution. In healthy FTs, we detected (many) STIC precancerous lesions. We can also simulate virtual sectioning as done in the clinic and show how current protocols undersample FTs. More here: www.biorxiv.org/content/10.1...

They’ve gone after: - the journalists - the historians - the scientists - and now, the comedians

Me fantasy of sitting down to properly read a paper

'Pneumonia struck first. Then tonsillitis spiraled into sepsis. Malaria battered him next, and after treatment, the other illnesses flared back up again. This unvaccinated 2-year-old boy is trapped in a relentless cycle.' www.npr.org/sections/goa...

The first September issue is live. www.embopress.org/toc/14693178... The cover features work by Cassie Clarke @cassiejclarke.bsky.social @cruk-si.bsky.social and co-workers showing that UPP1 supports #metastasis by altering #immune and ECM landscapes. -> www.embopress.org/doi/full/10....

🚨 DEADLINE APPROACHING! Abstract submissions are closing soon for the 2nd MRS ECR Virtual Meeting on Nov 18-19, 2025! Trainees & Junior Faculty (within 3 years of starting your lab), share your work! Abstract Deadline: Sept 12, 2025 - Submit here: bit.ly/47KLyp2 ❗Free registration for MRS Members!

Discovery of the number of ways cancer cell hijack other cells to promote their growth and spread keeps proliferating www.cell.com/cell/fulltex...

“We really need to recognize how debilitating endometriosis is. How underfunded endometriosis is. And how hard investigators have to fight to be able to study this disease.” www.science.org/content/arti...

The New Yorker…

NEW: First ever JEM Early Career Travel Award! 🎉 Grad students and early postdocs - you could get up to $1K to attend Cytokines 2025. Thanks to Rockefeller University Press and JEM for supporting the next generation of scientists! Apply: rupress.org/jem/pages/ea... #CytokineSociety #JEMTravelAward

📢 EJI is at #IUIS2025 in Vienna! Come meet us at the EFIS booth #42 😃 We’d love to hear about your science, answer your publishing questions, and connect with the global immunology community 🔬🌍 See you there! 👋 @yefis-immunology.bsky.social @efis-immunology.bsky.social @iuis-online.bsky.social