Happy to highlight an essay I wrote together with @marcdemanuel.bsky.social, @natanaels.bsky.social and Anastasia Stolyarova, trying to think through what sets the mutation rate of a cell type in an animal species: www.biorxiv.org/content/10.6... 1/n

We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n

🚨 15 days left to apply! Be part of EvoMG-DN and advance your PhD career in evolutionary genomics. 👉 www.evomg-dn.eu #PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA #HorizonEurope #EUResearch #ResearchOpportunities #PhDPositions

Very happy to share our work on signature SBS5. See Molly's thread for a short summary

In these dark times, it comes as a rare pleasure to highlight @natanaels.bsky.social ‬ & @marcdemanuel.bsky.social's work on germline and somatic mutations in humans. 1/n www.biorxiv.org/cgi/content/...

🚨🚨🚨 Please RT! We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets. Deadline: 30/09/25👇

I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required. Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.

Truly honored to be appointed an Ambassador for the ERC. Looking forward to keep advocating for the importance of frontier science in Spain, Europe, and beyond.

🚀 We are proud to launch the new "Ambassadors for the ERC" initiative, together with @ercgrantees.bsky.social ! We aim to empower researchers across Europe to advocate for frontier research. Find out more 👉 bit.ly/44bQzp7 🌟 Excited to see what can be achieved! #Amb4ERC

Posting on behalf of Shamil Sunyaev: Eimear(Vice Chair) and I (Chair) are organizing the 2025 Gordon Research Conference (GRC) on Human Genetics and Genomics, which will be held on July 6-11, 2025 in beautiful University of Southern Maine, Portland, Maine.

🔊 We're Hiring! 🔊 The #IBE seeks a Post-award Research Project Manager - European Projects. 🌍 📄 Full-time | 🕒 2-year renewable contract 📆 Apply by: 4th May Explore all our #JobOffers & #JoinOurTeam 👉 https://www.ibe.upf-csic.es/work-with-us/job-offers

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

“The distribution of highly deleterious variants across human ancestry groups”. Preprint with Anastasia Stolyarova and @gcbias.bsky.social: www.biorxiv.org/content/10.1...

Last days to apply!

📣 Two ERC-funded positions are available in the lab! If you are interested in exploring the mechanisms underlying mutation, we’d love to hear from you. PhD: shorturl.at/Oc04N Postdoc: shorturl.at/1ShHB RPs and shares would be greatly appreciated! 🧪🧬🖥️ #ScienceJobs #PostdocJobs

Most of the talks from our Oct meeting are now online, with a few more to come: www.precisionmedicine.columbia.edu/videos

📣 Two ERC-funded positions are available in the lab! If you are interested in exploring the mechanisms underlying mutation, we’d love to hear from you. PhD: shorturl.at/Oc04N Postdoc: shorturl.at/1ShHB RPs and shares would be greatly appreciated! 🧪🧬🖥️ #ScienceJobs #PostdocJobs

📢 Are you interested in doing a PhD in Life Sciences #VHIO? 🎓 PhD call open: 8-10 fully funded scholarships for international Life Sciences & Medical students 🧬 🩺 Apply now 👉 linke.to/PHDFellowshi... 🗓 Deadline for applications: 29th November 2024

In a new preprint led by @TheNikhilMilind, we explored a fascinating paradox: For many traits the number of duplications or loss-of-function (LoF) mutations is correlated with phenotype. Curiously, for most traits, the AVERAGE direction of LoFs and Dups is the SAME. Why?

Pls share 🌟Join the IMP as a Group Leader We are 👀 for a colleague, ready to lead a groundbreaking research program. Enjoy generous funding, outstanding facilities & a vibrant scientific community in one of the world's most livable cities @impvienna.bsky.social 👉https://tinyurl.com/impgl2025

Accepting postdoc applications to work on a broad range of topics including gene regulatory variation, response eQTL mapping, complex traits, comparative genomics in primates, and predictive models.

Here's a starter pack of people on here who I've found and who I know are excellent Science Communicators. Give them a follow: go.bsky.app/4SAvt2B

A thread with some new starter packs in genomics and bioinformatics 🧵 1/13...

I'm recruiting students / postdocs to join my new lab at the University of Rochester for Fall 2025 onwards! If you're interested in phylogenetic comparative methods, genome evolution, and/or computational biology, please get in touch! More info: mhibbins.github.io

Bioinformatics folks working on HPCs—anyone got a go-to alternative to vscode? It’s become mysteriously slow and unresponsive on our system lately

The new program of Evolutionary Medical Genomics, lead by @mirimiam.bsky.social, and shared between our Institute, CRG & UPF will hold its 1st symposium next week. Our work on unicellular relatives of animals and tumorigenesis will be represented by Yosuke. Link: evomedgenomics.com/events/inaug...

🧬🐭🐴🐻Job Alert🐻🐴🐭🧬 We are hiring 3 postdoctoral researchers in DeepTime Palaeogenomics! All positions are for 2 years (extension possible), & are fully funded both in terms of employment and project costs. Deadline: 2 Dec 2024 Please RT! Apply: www.su.se/english/abou...

Hi all! I'm excited to announce a tenure track faculty position in conservation genomics in EEB at UCLA! We're looking for candidates who use genomic tools to study evolutionary processes related to conservation. Note, the actual application deadline is Nov 29. recruit.apo.ucla.edu/JPF09875

Genomics, evolution, and more starter pack! Help build community with this starter pack. This list is currently incomplete. Want to be included? Reply and I will remedy that! go.bsky.app/JjvzkWU

Another starter pack of fine fine folks - New PIs! We're all figuring it out together! Please do (self-)nominate go.bsky.app/KJXNgfZ

Independent GroupLeader / PI position in AI in Genome Biology, Multimodal Omics at European Molecular Biology Lab (EMBL), Heidelberg! www.embl.org/jobs/positio... Looking in particular for researchers with quantitative/ methodological background who want to dive into leading edge biology research.

Now that blue sky is more active, I guess it’s time for my annual advertisement: I’m always keen to take on a new graduate student to study the evolution of species interactions, especially parasitism and immunity, maintenance of genetic variation, adaptation, speciation.

Applications are now open for Columbia's Zuckerman Institute Alan Kanzer Postdoctoral Fellowship. This is your chance to pursue pioneering research into critical aspects of the brain. bit.ly/KanzerFellows

Thrilled to announce that I’ve been awarded an ERC Starting Grant! We aim to uncover the timing and mechanisms of mammalian male germline mutation, as well as explore how primates lower their somatic mutation rates. The lab will be hiring soon—stay tuned! #ERCStG

1/ A thread about mutation and recombination in vertebrates and what we learned by studying three-generation pedigrees of zebra finches. Take home: the remarkable similarities between birds and mammals in many properties of these fundamental processes.

A thread about how meiotic recombination is directed to the genome in vertebrates, discovered by studying corn snakes. Work with @choge.bsky.social, @mollyprz.bsky.social, and co-authors: 1/n

Registration now open for the annual Probabilistic Modeling in Genomics meeting, to be held in Vienna April 10-12th 2024. Deadline for a talk or poster: February 15, 2024. See: events.vbc.ac.at/gmi_events/p...