I am SO THRILLED to share our first fully-lab lab paper!!!!!! Led by @hybridzones.bsky.social & @hagarsoliman.bsky.social, w/ a major assist from @pfschwarz.bsky.social!!!!!!!!!!!!! Read more below, if you're curious (you should be- it's AWESOME!!!!!!!) link: www.sciencedirect.com/science/arti...

The program for the 2026 New York Population Genetics meeting, hosted by at the @simonsfoundation.org on March 9th 2026, is now up: events.simonsfoundation.org/event/7c91dd....

Happy birthday to one of my favourite haters, Charles Darwin

Our work on the generalizability of polygenic scores (PGS) from the @arbelharpak.bsky.social Lab is now officially out! We examine the accuracy of PGS predictions at the individual level. We make 3 observations that expose gaps in our understanding of PGS “portability.” rdcu.be/e0LAr (1/27)

Pregnancy loss is common in humans, and chromosomal abnormalities are the leading cause. Using genetic data from ~140,000 IVF embryos, we show that maternal variation in meiosis genes influences recombination and aneuploidy risk. First authors: @saracarioscia.bsky.social & @aabiddanda.github.io

Just in: The Trump administration sent hundreds of letters Tuesday terminating federal grants supporting mental health and drug addiction services.

Come learn with us! #REU!

🚨My department is hiring a full-time Assistant Teaching Professor to teach undergrad Genetics & Genomics, upper-level Genomics, and an inquiry-based Computational Genomics course where students can do authentic research. 🧬💻 I’m on the search committee. DM me if you’re interested. Please share! 🙏

Happy to highlight an essay I wrote together with @marcdemanuel.bsky.social, @natanaels.bsky.social and Anastasia Stolyarova, trying to think through what sets the mutation rate of a cell type in an animal species: www.biorxiv.org/content/10.6... 1/n

How to keep in step when your (protein) partner speeds up… Here we investigated the adaptive remodeling of a protein-protein interaction surface essential for telomere protection. Congrats to whole team! www.science.org/doi/10.1126/...

Excited to share a preprint of my PhD project looking at interactions between SNPs and polygenic scores in the UK Biobank! A thread... 🧵 www.medrxiv.org/content/10.1...

SAVE THE DATE: the yearly NY Population Genetics meeting will be back on March 9 2026, generously hosted by the @simonsfoundation.org. Details to follow. Please RT.

An empirical approach to evaluating the prevalence of long-lived balancing selection in humans--and important limitations. Work by @hannahmm.bsky.social

We are searching for a Forest Ecophysiologist (tenure track Assistant or Associate Professor) to join the Department of Forest and Conservation Sciences, University of British Columbia Faculty of Forestry. Please share! Details are here: ubc.wd10.myworkdayjobs.com/ubcfacultyjobs

We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT

When sex chromosomes turnover, they can reset the rules of genomic conflict. New preprint exploring how turnover reshapes barriers to gene flow through an “escape-hatch” model for mitonuclear conflict. Any feedback would be welcome! ecoevorxiv.org/repository/v...

New today: We're petitioning NSF to revert GRFP eligibility criteria to last year's terms, to avoid pulling the rug out from under the earliest of early-career scientists who had every reason to think they'd be able to apply this year. Sign and spread the word! laurenkuehne.github.io/grfpChanges/

The GRFP announcement from NSF cuts out an entire cohort of 2nd year students from consideration, without warning. This is so deeply unfair that it warrants a formal protest from the scientific community. If someone wants to work with me to craft an open letter and solicit signatures, LMK.

As others have pointed out, the fellowship is now available only to 1st year grad students. (Left is last year, right is this year)

New: After a long wait, the GRFP solicitation is live! Deadlines have been extended to early November, so applicants have a bit over a month to submit. www.nsf.gov/funding/oppo...

Delighted to see this paper with @anaignatieva.bsky.social now published in Genetics! academic.oup.com/genetics/adv... We tackle a thorny issue arising in statistical tests for genetic interactions (epistasis) using ancestral recombination graphs (ARGs)... 🧵

First pop gen paper from our lab! We find repeated evolutionary turn over of sex chromosomes in darters contributes to reproductive isolation. Turnover may be an escape hatch to resolve mitonuclear conflict & neo sex chromosomes evolved via a rare recessive mutation. www.biorxiv.org/content/10.1...

Very happy to share our work on signature SBS5. See Molly's thread for a short summary

In these dark times, it comes as a rare pleasure to highlight @natanaels.bsky.social ‬ & @marcdemanuel.bsky.social's work on germline and somatic mutations in humans. 1/n www.biorxiv.org/cgi/content/...

Trump admin planning to change student visas from lasting for duration of academic program to fixed 4-yr term, and then much harder to renew Could destroy US ability to attract global talent, particularly those seeking advanced degrees in STEM. The median time to complete a PhD is 5.7 yrs per NSF.

This seems like a wildly useful resource for students applying to college and trying to compare costs - collegetables.info The cost after need-based financial aid varies widely, and often not in ways one might expect

Why do males and females often differ in traits? The expected answer: selection. But our new paper in GENETICS shows that genetic drift alone can generate sexual dimorphism — even when male & female optima are the same

Full paper now out in GENETICS: The relationship between sexual dimorphism and intersex correlation: do models support intuition? 🔗 academic.oup.com/genetics/art... #Evolution #QuantGenetics @GeneticsGSA

Not sure how many scientists here have tried Claude Code or similar command line coding assistants. I had a complicated family property tax problem that was best solved by a brute force Monte Carlo simulation approach, so I spent a few days coding up and analyzing a model with Claude Code.

I'm thrilled that my lab at NYU is now supported by an NIH MIRA grant! I'm looking to hire 1-2 senior lab members (outstanding postdoc candidates or experienced staff scientists) with expertise in computational or statistical methods in human genetics or genomics. Please share!

hey folks! so looking forward to seeing everyone at @sse-evolution.bsky.social! if you have space on your schedule, come check out the Kreiner lab contigent on Sunday morning in the Adaptation VI symposium.

Let me remind you: we don't have kings in America — and I won't bend the knee to one. Never stop speaking out and showing up, Illinois. This is what democracy in action looks like.

Here’s a New York Times photo of the Chicago “No Kings” rally. NYT said the march that followed spanned at least 10 blocks.

The #NoKings march in Chicago stretched for blocks and blocks and blocks - No monarchs here! (except for butterflies and drag kings + queens)

Excited for our publication on how the geographic scale of a sample affects the discovery of rare, deleterious variants to be out this week. With a mix of theory, simulation, and data analysis, we show when samples are narrow vs broad, the number of variants discovered and their frequencies change

I'm excited to announce that I'll be starting a lab at UCSF in the @ihgatucsf.bsky.social and @ucsf-epibiostat.bsky.social in July. We'll work at the intersection of statistical genetics, population genetics, and machine learning.

I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required. Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.

Out today in @pnas.org! www.pnas.org/doi/10.1073/...

Jennifer Blanc and @jeremyjberg.bsky.social use theory and simulations to study the process of testing for an association between polygenic scores and axes of ancestry variation when confounding factors are present. Learn more about their findings in #GENETICS: buff.ly/EmKpXyP

Our lab is moving! I’m thrilled to be joining the Department of Ecology & Evolution at the University of Chicago this fall. I’ll be recruiting PhD students so please spread the word and reach out if interested!

When should adaptation arise from a polygenic response versus few large effect changes? https://www.biorxiv.org/content/10.1101/2025.05.15.654234v1

Racist and sexist roots in the cancellation of NSF grants under Trump: Grants with female PIs canceled 2x more than men Grants with Black PIs canceled 4x over White PIs Grants with Hispanic PIs canceled 2x over White PIs Grants with PIs with disabilities canceled 2x more than without

Postdoc job opportunity! We're looking for ECR in evolutionary genomics to study the relation between intra-specific gene expression variability, polymorphism, and macro-evolutionary rates. We have the data in 3 fishes & amphioxus, just waiting for your expertise and enthusiasm! tinyurl.com/3aewk286

It's going to be increasingly important to read foreign news coverage of US politics as the domestic US media gets more afraid of continuing threats & intimidation from the Trump regime

It's infuriating that grant mechanisms intended to improve diversity in science are frozen-those apps are identical to other career development award apps-but we advised students from underrepresented groups to apply to the special mechanism. And now they, specifically, are losing their funding.

Several Columbia Univ student journalists are suspended after covering protests (while wearing press ID) in the main library. Their access to campus is blocked, and they can't take final exams. Also: Columbia's acting president is a former ABC journalist www.columbiaspectator.com/news/2025/05...

Top scientists are cutting staff. Postdocs are leaving the country. Promising students – can't find labs. How the Trump cuts to science are playing out. @uwnews.bsky.social www.nbcnews.com/science/inno...

And then called the NYPD and violently arrested them, while sending out emails about the terrible disruption to studying that was caused by peaceful protesters in one room of one library. There aren't words to describe how disgusting and hateful this is.

Thirty-eight of 43 experts cut last month from the boards that review the science and research that happens in laboratories at the National Institutes of Health are female, Black or Hispanic, according to an analysis by the chairs of a dozen of the boards.