Delighted to share our latest preprint "Filopodia-mediated trans-endocytosis" www.biorxiv.org/content/10.6... Work driven by many people including Hanna, Marcela, Sujan, Marie-Catherine, Anna and Monika. Fantastic collaboration with Johanna Englund, Emilia Peuhu, and Eija Jokitalo

As always preprint formated using the #RxivMaker engine created together with @henriqueslab.bsky.social github.com/HenriquesLab...

Check out the tour de force by @jalehtimaki.bsky.social in its final form: www.sciencedirect.com/science/arti... . An elegant combination of transcriptomics, F0 screens and high end imaging unravels the cues that guide cells (here retinal horizontal cells) in an increasingly crowded tissue. #proudPI

After 15 years as Editor-in-chief (EiC), Michael Way @drmichaelway.bsky.social will be stepping down at the end of 2026 & we are seeking feedback from the cell biology community as part of the consultation process for appointing a new EiC. We'd love to hear from you: www.surveymonkey.com/r/GZCC9F9

I made sausage pasta on Tuesday night and @manuelthery.bsky.social approves youtu.be/ZutJ8fzIDRQ?...

We have been thinking a lot recently on how to share and interact with code when doing image analysis. This is one piece of the puzzle. Awesome work driven by Bruno S. Always a delight to work with @henriqueslab.bsky.social 🫶 More to come soon 😄.

Congratulations, @bioimagearchive.bsky.social! This pubic data repository has received @elixir-europe.org’s CDR and EDD status! Great recognition for a great resource! 🎉 Learn more🔽 www.eurobioimaging.eu/news/bioimag...

📯👨‍🚀 Calling all #bioimage analysis aficionados. #EZInput is out! We wanted to bring #ImageJ’s capacity to record settings to the #Python ecosystem 🐍. It is a declarative library for generating UIs that just work. Done with @guijacquemet.bsky.social lab arxiv.org/abs/2601.08859 #ScientificComputing

🚨The Neurocyto lab is branching out in our latest preprint! We used tubulin microinjection to directly visualize microtubule turnover in developing hippocampal neurons, demonstrating the presence of in-lattice repair and a selective stabilization in the nascent axon. Check below, or read on 🧵 1/9

Congrats to the newest PhD graduate at our lab, supervised by @henriqueslab.bsky.social, now Dr. @afonsomendes92.bsky.social!👨🏼‍🎓👏 His research work culminated in the publication of #SReD in Nature Communications. Read here: tinyurl.com/NatureSRed @gimmfoundation.bsky.social @itqbnova.bsky.social

👁️I spy our Scientific Advisory Board members on the @jcellsci.bsky.social cover. FocalPlane is a youngster at 5 years old, but we're looking forward to continuing our development in 2026 with the help of the #microscopy and #cellbio communities.

One of my favorites features is that you can now cite using DOI in line with the text. #RxivMaker automatically fetches the citation and update your documents. No more messing around with Biblitex ❤️

🚀📰 End-of-year news for #RxivMaker =). Now it generates both #pdf and #docx from #markdown. Docx makes it easier to collaborate on a document for non-markdown users, making it simple to loop between docx and #RxivMaker to a professional-looking #preprint Preprint updated: arxiv.org/abs/2508.00836

On my last day in the lab for 2025… I sneak into the h-index 40 club to join @henriqueslab.bsky.social! #celebrateallthethings

🧬 @itqbnova.bsky.social has 15 BRIDGE fellowships for Master's graduates pursuing PhDs! We have a spot: "Decoding the morphological language of infection using AI". Build AI to map how viruses hijack cells & bacteria survive antibiotics. Deadline: 05/01/2026 www.itqb.unl.pt/education/br...

Going through my UCL-times photos, this little one came up

🛠️Why this matters: PhotoFiTT empowers labs to fine-tune imaging conditions, improve reproducibility, reduce cell stress, and strengthen biological conclusions. All code, data & tools are open on GitHub & BioArchive 🔓📦 #OpenScience 👉 github.com/HenriquesLab...

💡 Key insights we uncovered: Near-UV light delays mitosis at doses as low as 0.6 J/cm². Longer wavelengths need higher doses, and surprisingly, continuous low-intensity illumination (slow scan) can be more damaging than brief high-intensity bursts (fast scan). Data-driven phototoxicity thresholds! ✨

🚀 Enter PhotoFiTT: a standardise experimental protocol combined with AI-powered image analysis to track cell behaviour (mitosis, size, activity) in response to light exposure. What’s even better: label-free and fully quantitative! 🔍🤖

The challenge: live-cell fluorescence microscopy can unintentionally stress or harm cells, changing timing, size and activity. If left unchecked, this can skew biology and standard qualitative checks just don’t cut it ⚡️ #Microscopy #CellBiology

It’s FINALLY out! 🎉🚀 We have been working on PhotoFiTT for a long time, and it’s now published, introducing a quantitative framework to measure phototoxicity and optimise live-cell microscopy experiments. So excited to finally share the last version! 🔬✨ #PhotoFiTT doi.org/10.1038/s414...

#PhotoFiTT proposes a standard label-free and quantitative protocol, including #AIImageProcessing, to measure #phototoxicity derived cell stress 🧮 By systematically assessing deviations in cell behaviour, we can optimize #livecell experiments and stop blindly frying our cells💡🧫

🚨Amazing news for a cloudy Monday!🌩️😎 I'm extremely happy to share that our last adventure is finally out!🚀🎉Phototoxicity fitness time trial (#PhotoFiTT) - a quantitative framework for assessing phototoxicity in live-cell microscopy experiments 🔬❤️‍🔥⚡️ doi.org/10.1038/s414...

We hope #PhotoFiTT becomes part of your standard toolkit for benchmarking phototoxicity⚖️reporting light exposure✅+sharing more reproducible imaging results🦾May quantitative phototoxicity assessment be a norm, not an afterthought✨ User-friendly code👩‍💻👉 github.com/HenriquesLab...

Huge thanks to all the amazing co-authors Leonor Morgado, Raquel Portela @guijacquemet.bsky.social and @microbematos.bsky.social @aiopticalbiolab.bsky.social 🌸💖🙏

As if a full photodamage odyssey wasn’t enough😏, we also had the excitement of moving institutes mid-project to @itqbnova.bsky.social 💚 New place, new microscopes, new experiments, new prizes and yet more fun!🤩

With the best partner in crime @mariodelr.bsky.social😎 this adventure started when joining @henriqueslab.bsky.social From day-1, #phototoxicity was a nightmare+obsession, but also as much about deep learning (beyond images), endless discussions+experiments and true joy as it was about microscopy 🔬💪

🎉 Last but not least, a huge thanks to @gomez-mariscal.bsky.social Leonor Morgado, Raquel Portela, @guijacquemet.bsky.social @microbematos.bsky.social @henriqueslab.bsky.social We have been an amazing team, and you made this work possible! 🥳🚀

Our Researcher @mariodelr.bsky.social and Raquel Portela from @microbematos.bsky.social were invited by @healthnewspt.bsky.social to talk about their new collaboration project awarded by Early Career Research Award, 𝗜𝗻𝗳𝗲𝗰𝘁𝗼𝗙𝗶𝗧𝗧. Read the full interview at: tinyurl.com/infectofitt

🚨🔬🤖🚀 #PhotoFiTT is out! With @guijacquemet.bsky.social's & @microbematos.bsky.social's labs, we launched a new phototoxicity measurement for live microscopy using cell clocks⏱️. By rockstars @mariodelr.bsky.social @gomez-mariscal.bsky.social et al! AI-powered + label-free doi.org/10.1038/s414...

Latest from the lab "Filopodome proteomics identifies CCT8 as a MYO10 interactor critical for filopodia functions " www.biorxiv.org/content/10.6... Work driven by @anagracanin.bsky.social A great collaboration with @ivaskalab.bsky.social and @bengoult.bsky.social

Checkout @guijacquemet.bsky.social team amazing work ❤️

I also used #RxivMaker by @henriqueslab.bsky.social to format our preprint arxiv.org/abs/2508.00836

🚀 New preprint out! We introduce SMOLM-LFM: a simple, ratiometric, light-field–based method for 6D single-molecule orientation + localization, no polarization optics, no complex PSFs. Fast.Robust.Large DoF. A work done at @henriqueslab.bsky.social. In colaboration with the great L. AlemanCastaneda

Wuhuuu, preprints using the #RxivMaker engine are popping 🍾

Also, the PDF or our preprint was created with Rχiv-Maker @henriqueslab.bsky.social rxiv-maker.henriqueslab.org Paper: arxiv.org/html/2508.00...

Feeling incredibly grateful to be awarded a generous #HealthResearch grant from @caixaresearch.bsky.social and FCT. In this project we will team up with Justin O´Sullivan @drjosull.bsky.social and Gaia Novarino @istaresearch.bsky.social.🧬🎉

Our community is celebrating once again: three projects led by #i3S researchers Diogo Castro, Ana Paula Pêgo, and Bruno Sarmento were awarded today by the @caixaresearch.bsky.social, totaling three million euros in funding. Congratulations! 👏 📰 tinyurl.com/y3ehbkp7

Great news for @aiopticalbiolab.bsky.social! @henriqueslab.bsky.social has been awarded #HealthResearch grant from @caixaresearch.bsky.social.🎉 This milestone strengthens the pursue of our scientific objectives and represents an important step forward for the future of our lab.🔬 #laCaixaFoundation

Light from high-res microscopes can damage cells and limit the study of viral infection cycles. With a #HealthResearch grant, @henriqueslab.bsky.social (@itqbnova.bsky.social#HealthResearch uses AI to adjust light in real time and boost our understanding of infectious diseases. https://tinyurl.com/3y8zwyes

1/ Many genetic changes linked to autism spectrum disorder are found in DNA regions that control gene expression. Supported by the #HealthResearch grant ➕ FCT, Diogo Castro @neurogenesis-i3s.bsky.social#HealthResearchinvestigates how these changes affect brain development. https://tinyurl.com/yjh7j59c

We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji. It ships many new features, detailed below, but that are articulated around the following:

Congrats to @henriqueslab.bsky.social for the @caixaresearch.bsky.social Health grant! 👏 The project will use AI to create smart microscopes that automatically adjust their lighting in real time, letting us watch the viral infection process over days. 🔗Know more: shorturl.at/yi9Rz

Extremely thankful to @caixaresearch.bsky.social for supporting our vision, and to all the amazing collaborators who enable our research. It takes a vilage and this is a road we walk together. Now onwards to make those scopes go pew pew only when needed

Check this out! A napari plugin for AI-based analysis of microbial bioimages! 🔬🦠💻

🔥 Innovation at #SPAOM2025! From Hot Topics in #Bioimage Analysis & #AI 🤖🔬 to Industry Talks & Pitches, today’s sessions showed how science and technology unite to transform #imaging and discovery! Thanks to all speakers, sponsors & participants for the inspiring discussions 🙌✨ #Microscopy #SPAOM

@spaommeeting.bsky.social has started already 🌟 it's amazing seeing some colleagues again and feeling our vibrating local community 🤩 Day I started strong with neurosciences, AI, image quality assessment, pathology, live cell imaging and all the incredible workshops!

🎉 Highlights from #SPAOM2025! From cutting-edge sessions on #AI & Smart #Microscopy 🔬🤖 to our lightning-fast flash talks ⚡, today’s speakers shared brilliant ideas driving the future of imaging and discovery! Huge thanks to all presenters for the inspiring insights and energy 🙌

Yesterday at #SPAOM2025: here’s what happened! 🙌 🔬 Quantum #Bioimaging & Sensing 🏢 Industry-sponsored Research Talk (Evident) 🚀 Industry Pitches Incredible talks, inspiring ideas, and cutting-edge innovation shaping the future of #microscopy! Huge thanks to our speakers & attendees! 👏

Come! We're hosting a fantastic list of speakers and hands-on workshops #ims2026