🧠 Study in "Science Advances": Impaired spatial orientation found in older adults at risk for #Alzheimer’s disease 👉 @newsmedical.bsky.social: www.news-medical.net/news/2025090...

Study by DZNE scientists in "Science Advances" using VR technology shows that individuals with SCD - and thus increased risk for dementia due to 🧠 #Alzheimer’s - can have impaired spatial orientation skills. 👉 @sciencefocus.bsky.social: www.sciencefocus.com/news/spatial...

Dragomir Milovanovic and coworkers @dzne.science dissect the structures and dynamics of actin polymerization upon biomolecular condensation of synaptic vesicles and phosphoprotein synapsin-1 during neurotransmission www.embopress.org/doi/full/10....

🏆 DZNE scientist Mikael Simons (Munich) has been selected as a 2025 #TauopathyChallengeWorkshop grantee by the #RainwaterCharitableFoundation: 👉 www.dzne.de/en/im-fokus/...

🧠 The human brain ages less than thought and in layers – at least in the area of the cortex responsible for the sense of touch. See study @natneuro.nature.com by @estherkuehn.bsky.social and colleagues at DZNE, @hih-tuebingen.bsky.social and @uni-magdeburg.de: 👉 www.nature.com/articles/s41...

🧠 Research by DZNE scientists and colleagues gives insights into olfactory deficits in #Alzheimer's disease: 👉 www.nature.com/articles/s41...

Profiling the proteomes of key organs across the entire mouse lifespan reveals organ-specific as well as systemic alterations associated with aging Dan Ehninger et al @dzne.science www.embopress.org/doi/full/10....

📢 Join us for the last talk of the semester in our Neurocolloquium, the "Hertie Network Lecture" on July 17 at 4.15pm: Susanne Wegmann (DZNE Berlin) @dzne.science will talk about "Cause & Consequences of neuronal Tau protein ‘activation’" 🙌 Host: @debkrov.bsky.social 👉 Zoom link tinyurl.com/32ku5jth

New work from the Milovanovic lab just out in Nature Neuroscience: Intersectin and endophilin condensates prime synaptic vesicles for release site replenishment 👉 www.nature.com/articles/s41...

🔬Researchers from DZNE, @lmumuenchen.bsky.social, and @tum.de have found that the enzyme “gamma-secretase” – implicated in #Alzheimer’s disease and cancer – selects its substrates according to a complex scheme of molecular features. 👉 @natcomms.nature.com: www.nature.com/articles/s41...

🧠 DZNE scientist Gerd Kempermann comments on recent paper in @science.org that provides new evidence for neurogenesis in adult humans. 👉 www.science.org/content/arti...

Gratulerar! Award for groundbreaking AD research. Lars Lannfelt, one of the pioneers behind "Lecanemab", has been honored with the Hartwig-Piepenbrock-DZNE-Prize. He receives the award for his outstanding contributions to the development of new therapeutic approaches for neurodegenerative diseases.

Using a digital version of the “Archimedes spiral drawing task” in about 8,000 participants of the #RhinelandStudy, DZNE scientist found that poorer performance, reflected smaller volumes/thinner cortices in several brain regions. 👉 @ebiomedicine.bsky.social : www.thelancet.com/journals/ebi...

🥂 Dr. Maria Eugenia Bernis received the 2025 GNPI Science Prize! She showed caffeine can help protect newborn brains after oxygen deprivation. In a preclinical model, just 3 days of caffeine treatment significantly reduced brain damage and inflammation by modulating the AMPK/mTOR signaling pathway.

Neurobiologist Frank Bradke is a new member of the @bbaw.bsky.social. Congratulations! 📸: BBAW 👉 www.dzne.de/en/im-fokus/...

Congratulations to Dieter Edbauer for his @erc.europa.eu "Advanced Grant", which he will utilize to decipher the nerve diseases ALS and FTD. 📸: DZNE / Frommann 👉 www.dzne.de/en/im-fokus/...

New work out of DELCODE www.medrxiv.org/content/10.1...

And there's also new work from Göttingen. 👉 www.mdpi.com/2311-553X/11...

New work out of Magdeburg. 👇

Congratulations to Christian Haass (@haasslab.bsky.social)! He receives an honorary doctorate from the University of Eastern Finland for 30+ years of groundbreaking Alzheimer’s research on beta-amyloid proteins and new therapeutic approaches. 📸: UFE/Raija Törrönen & UFE/Niko Jouhkimainen

Why do we get sick? Helmholtz studies health, lifestyle & environment through NAKO & Rheinland – to prevent disease before it starts. 🔗 Read more: t1p.de/ario4 #Helmholtz30 @helmholtzhzi.bsky.social @mdc-berlin.bsky.social @dzne.science @www.helmholtz-munich.de

How can swarm intelligence improve stroke treatment? A research project links central registry data with local brain imaging – powered by artificial intelligence. Funded by @www.helmholtz.de and under paricipation of @cispa.de. 👉 www.dzne.de/en/news/pres...

Paper alert! Congrats @martinfuhrmann.bsky.social and colleagues!

📢 Our new study is now published in Communications Biology: We demonstrate deep in vivo #ThreePhoton imaging 🔬 of neurons 🧠 and glia in the medial prefrontal cortex with subcellular resolution! 👉 www.nature.com/articles/s42... #Neuroscience #CalciumImaging #Microglia #DZNE @dzne.science

Helmholtz Health (@www.helmholtz-munich.de, @dkfz.bsky.social, @mdc-berlin.bsky.social, @dzne.science, @helmholtzhzi.bsky.social, @hzdr.bsky.social) is shaping the future of healthcare with innovative technologies – driven by AI, biomarkers, and sensors. 🔗 Learn more: t1p.de/e3cgm #Helmholtz30

Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration @janos-groh.bsky.social @tum.de @synergy-munich.bsky.social @dzne.science www.nature.com/articles/s41...

Woohoo!! A proud DZNE is part of three Clusters of Excellence: @neurocure.bsky.social (Berlin), @immunosens.bsky.social (Bonn), and @synergy-munich.bsky.social (Munich). These top research networks will receive 7 more years of funding from 2026. #ExcellenceStrategy #Neuroscience

Paper Alert! “Immersive Virtual Reality for Older Adults: Challenges and Solutions in Basic Research and Clinical Applications” In this review the @wolberslab.bsky.social: Highlights design & usability issues - Suggests practical solutions - Shares key recommendations 👉 doi.org/10.1016/j.ar...

Paper alert! @davidberron.bsky.social and team tackled: What are the recent advances in remote and unsupervised digital cognitive assessment of preclinical AD? The review covers 28 studies and 23 tools, offering a clear overview of recent advances and challenges. 👉 www.nature.com/articles/s41...

Public Voting for the Helmholtz Imaging Awards just opened - I might be a bit biased, but there are some beautiful neuronal rosettes 🧠 here from my students Teresa & Begüm 🤩 If you have a moment please support them with your vote 🗳️👇 & share the word ✉️ #HIBestImage25 #ScienceArt

📢 We are #hiring a #PhD student to work on an interdisciplinary, collaborative project @dzne.science in Bonn, Germany! 🧠 If you’re interested in western diet-induced #neuroinflammation and innate immune signalling in #alzheimersdisease, check out our ad below 👇 jobs.dzne.de/en/jobs/1014...

📘 The book "Cultural Psychology. An Introduction" is now available in English! My chapter “Material Poverty and Symbolic Precarity” explores how poverty can be understood through a cultural‑psychological lens. 👉 link.springer.com/chapter/10.1...

New research by scientists of DZNE's population-based "Rhineland Study" indicate that retrotransposable elements and their repressors are markers of aging and that their dysregulation is linked to inflammation, especially in men. 👉 onlinelibrary.wiley.com/doi/10.1111/...

New findings from Hayder Amin from our Dresden site. He and his team have answered the following question: "How do genes and electrical signals interact in real tissues—and how does that shape behavior, health, or disease?" advanced.onlinelibrary.wiley.com/doi/10.1002/...

#Microglia and CD8⁺ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15, say Aleksej Frolov, Hao Huang (@haohuang0086.bsky.social), Ralf Stumm, Elvira Mass (@masslab.bsky.social) Marc Beyer @dzne.science and colleagues: rupress.org/jem/article/... #omics #RareDisease

🎥 Watch a short video summary of this study (rupress.org/jem/article/...) from Aleksej Frolov and @haohuang0086.bsky.social! 👇 youtu.be/KEpAWt_NCkI

🧠 Neuroinflammation: Research by DZNE, @unibonn.bsky.social and others suggest that an over-active immune system of the brain is a driving force in “spastic paraplegia type 15”, a rare neurodegenerative disease associated with movement disorders. 👉 Paper @jem.org: rupress.org/jem/article/...

🧠 Individuals with a genetic predisposition to Alzheimer’s show altered 🩸 blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia. Paper by DZNE and partners in “Alzheimer’s & Dementia”. 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

How a Missing Gene Speeds Up Aging: New Insights into Telomere Health 🔬 A new study from #HelmholtzMunich, in collaboration with DZNE, CNIO and NCI, reveals how the gene #TEN1 plays a crucial role in maintaining the health of our chromosomes. 👉 t1p.de/j2wf2 @dzne.science #AgingResearch

Thrilled to be at #ADPD2025 in Vienna ☀️ Thanks to everyone who came to our session on innate immunity yesterday! Really enjoyed the discussions after on our findings on #metabolism & #microglia function in #alzheimer’s disease I’ve learned a lot at this meeting - looking forward to Copenhagen 2026 🧠

We are thrilled to share the wrap-up of the PREDICTFTD project Kick-off Meeting! @erasmusmc.bsky.social @leitat.bsky.social @dzne.science @unihalle.bsky.social @idibaps.bsky.social @ohenews.bsky.social www.youtube.com/watch?v=hwhH...

Survey Study Aims to Assess Germany’s Readiness for Early #Alzheimer Diagnosis Using Biomarkers #ADPD2025 👉 www.neurologylive.com/view/survey-...

🚨 New research alert! 🚨 Our latest study here at @unibonn.bsky.social and the Systems Medicine at @dzne.science , published in @naturemedicine.bsky.social reveals just how dramatically diet influences health 🥗

🍽️ Western diet causes inflammation, traditional African food protects. Study in @naturemedicine.bsky.social, close collaboration with partners from @radboudumc.bsky.social (Netherlands) 🇳🇱 and KCMC University (Tanzania) 🇹🇿 👉 www.nature.com/articles/s41...

Hans-Ulrich Fried holds a doctorate in neuroscience and has been Head of the Light Microscope Facility at @dzne.science in Bonn since 2010. Together with his team, he is responsible for 35 state-of-the-art light microscopes, some of which he developed himself.

🧠 🏆 Congrats DZNE scientist Christian Haass @haasslab.bsky.social On a recent gala in Paris, he was awarded the "Grand Prix Européen 2024" by the "Fondation Recherche Alzheimer" for his research on #Alzheimer's. 👉 youtu.be/kDe8nuGkn2E?...

Intermittent Fasting Increases Sex Drive in Male Mice: An Approach for Low Libido in Humans? Current findings could point the way for new therapy option / Serotonin plays key role. Hot off the press from our Bonn based group of Dan Ehninger. 👉 www.cell.com/cell-metabol...

The first plenary lecture of the #NWG2025 @neurowissg.bsky.social is there! Frank Bradke @dzne.science delivers lecture about axon growth and regeneration. Great to learn about the importance of microtubules! 🤩🧠

Stellar presentation by Frank Bradke with a very impressive attendance!

Join us at the #iBehave #Symposium "Circuits for Behavior: Cross-species Strategies for Adaptation & Plasticity" at the NWG Meeting in Göttingen chaired by @jangrundemann.bsky.social & @ggatto.bsky.social 📅Mar 27 ⏰14:30 - 16:30 📍Lecture Hall 10 @unibonn.bsky.social @UKB @mpinb.mpg.de @dzne.science