Hierarchy in neuronal representations of multiple tasks in prefrontal cortex www.biorxiv.org/content/10.6...

Really nice work from the Holmes lab looking at amygdala astrocytes in fear memory and extinction! www.nature.com/articles/s41...

New paper alert! 🚨 We found that the brain's compass is remarkably stable at two scales 1️⃣ the system maintains its internal organization for weeks 2️⃣ It "remembers" its orientation for weeks, even after a single visit This may be key to how the brain aligns its other maps. Paper: rdcu.be/e3waP

🔬🧠 Releasing the 1.0 version of #Suite2p and THE PAPER w/ @marius10p.bsky.social! Now with GPU acceleration. Want to use Suite2p but don’t have 100,000 neuron recordings? We show you how to get those with a standard 2p microscope #neuroscience #imaging #neuroAI www.biorxiv.org/content/10.6...

🚨 new work from the lab on how eye movements 👀 versus orofacial movements influence 🐭 visual cortex activity 🧠 #neuroscience #behavior #neuroAI

Coordinated activity and plasticity of infralimbic cortex GABAergic interneurons are critical for fear extinction encoding https://www.biorxiv.org/content/10.64898/2026.02.07.704584v1

✨ New 3D pose estimation method from my lab! #FMPose3D allows for monocular (i.e. single camera) 2D➡️3D 🔥 Led by Ti Wang & w/ Xiaohang Yu #FMPose3D is SOTA on human & animal 3D benchmarks, & will be integrated into @deeplabcut.bsky.social ⬇️ 📝 arxiv.org/abs/2602.05755 ➡️ xiu-cs.github.io/FMPose3D/

How does neuronal gene expression evolve over time in response to experience? CytoTape will help us find out - a major milestone for neuroscience, providing new ways to study memory & aging 🧠 Congrats to the whole team! Looking forward to our continued collaboration on this work 🎉

Very thankful for this thoughtful dispatch by @shaisrael.bsky.social sky.social and Moshe Parnas about our work. Learning and memory: Forgetting to remember: Current Biology www.cell.com/current-biol...

Now out in @currentbiology.bsky.social: neuroscientists in the lab of @felsenberg.bsky.social found that in fruit flies, re-tasting a sugar reward can weaken past memories, pointing to new ways to safely update harmful ones. www.fmi.ch/news-events/...

Finally we got to see live AISs in our hands! 2-photon imaging of AnkG-GFP 💥 Absolute banger tool for the AIS field developed by @pjenkinslab.bsky.social et al!

An updated version of the following paper is now available on bioRxiv: Early spatial and contextual coding deficits in hippocampal CA1 precede performance decline in an Alzheimer's disease model. Yimei Li, Mary Ann Go, Hualong Zhang, Simon R Schultz. www.biorxiv.org/content/10.1...

Excited to share the latest work from the lab—a true tour de force led by @nbaumgar.bsky.social. TLDR: We report a novel endogenous mechanism whereby cycling ovarian hormones alter threat memory expression through state-dependent recruitment of the lateral septum to the memory ensemble. 🧵⬇️

Turns out deep neural networks are better at extracting relevant features than I am... Meet "DeepUnitMatch", a DNN version of our neuron tracking tool: www.biorxiv.org/content/10.6... It has been a privilage to continue the collaboration with Célian, and cosupervise the talented Suyash & Wentao!

A special year for the Cajal Course in Computational Neuroscience: the BRAIN Prize winners Haim Sompolinsky and Larry Abbott will join us as keynote speakers. And we will bring you the same great roster of instructors as every year. Applications are now open! cajal-training.org/on-site/comp...

"These findings challenge the traditional brain-centric view of reward processing, supporting a more integrated model in which vagus-mediated interoceptive signals intrinsically shape motivation and reinforcement." Awesome work by @peppeganga.bsky.social & his team 👏 www.science.org/doi/10.1126/...

Unconstrained Plasticity Disrupts Memory Consolidation in a Mouse Model of Rett Syndrome https://www.biorxiv.org/content/10.64898/2026.01.29.702595v1

We think cortex might function like a JEPA. It looks like prediction errors in layer 2/3 are not computed against input (as is the idea in predictive processing), but against a representation in latent space (i.e. like in a JEPA arxiv.org/abs/2301.08243 or RPL doi.org/10.1101/2025...).

Our new work is out in Science Advances. We show that neural activity in the striatum reflects not just cortical inputs, but also often-underappreciated thalamic inputs. www.science.org/doi/10.1126/...

How does evolution turn a harmless bacterial feeder into an active predator? Our new study led by @marianneroca.bsky.social and published in @pnas.org explores how sensory systems were rewired to enable prey detection and predatory behaviour in nematodes. www.pnas.org/doi/10.1073/... 🧵below!

If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd parisneuro.ovh

we built squeakpose studio. now there’s a preprint so i can stop explaining it in slides. modern computer vision. ultra-fast training and inference. model-assisted labeling. analysis out of the box. real-time edge deployment on whole frames at 120 fps (which felt reasonable at the time).

My perspective in @thetransmitter.bsky.social on why emotion research feels stuck and how we might move forward—by focusing on how the brain uses internal brain models to shape emotional processing across species. www.thetransmitter.org/emotion/why-...

How do past sensory experiences prepare us for new ones? Our new paper tackles this long-standing question, revealing a role for activity sequences in the olfactory bulb. Excited to share our work led by @jonvgill.bsky.social with Mursel Karadas & Shy Shoham www.biorxiv.org/content/10.6...

Excited for the publication of our recent work on how pyramidal cells shape the identity of interneurons in the Cortex! Big shout out to @artofbiology and Sherry Jingjing wu! www.nature.com/articles/s41...

Our latest paper is out in Nature 🥳 We investigated the underlying neuromodulatory regulation of aggressive behavior in the nematode Pristionchus pacificus 🪱🧠🔬 And we show that novel behaviors can evolve through changes of single neuron function by switches in neuromodulator-receptor expression. 👇

An interactive 3D atlas of gene expression in the mouse brain https://www.biorxiv.org/content/10.64898/2026.01.20.700446v1

Memory erasure by dopamine-gated retrospective learning https://www.biorxiv.org/content/10.64898/2026.01.17.700100v1

What's the relation between voltage and calcium in dendrites? Xiang Wu studied this in CA2 hippocampal pyramidal cells in behaving mice. www.biorxiv.org/content/10.6...

How do new behaviors evolve? A new Nature study shows how predatory aggression can emerge through changes in neuromodulatory circuits – without adding new neurons. We’ve created a short animated explainer video to walk through the key ideas. youtu.be/wNhjKDCPs_8?...

First joint work between @jameslightfoot.bsky.social and my lab is now published! Machine-learning, aggression, genetics, beautiful fluorescent transgenics and evolution! You can find it all!

Why do some worms graze on bacteria while others hunt and kill? Our study, published today in Nature, reveals how predatory aggression evolved in nematodes. Led by @gunizgozeeren.bsky.social and @leoboeger.bsky.social across the @jameslightfoot.bsky.social and @monikakscholz.bsky.social labs.

Explicit and implicit modularity that emerges in simple neural network models even in the absence of anatomical constraints. Whether modularity emerges or not strongly depends on the geometry of the inputs and other factors. Extensively revised article with many new results. With @wjj.bsky.social

Ultrafast Frame-Free Imaging of Neural Activity with Event Cameras https://www.biorxiv.org/content/10.64898/2026.01.08.698496v1

Mapping subcortical fear pathways in the human brain: thalamo-amygdala connections revealed by high-resolution tractography https://www.biorxiv.org/content/10.64898/2026.01.07.697914v1

The new Cajal Center is opening 8 CSIC permanent research positions (CT, IC & PF levels) via national competitive exams. We welcome candidates eager to shape an ambitious 🧠 research hub in Spain. 🔗 sede.csic.gob.es/tramites/con... 📣 #Neuroscience #CNC #CSIC #ScienceJobs 👇🏼

Hot off the @nature.com press!! Our A-SOiD behavior library developed specifically for pain to quantify a new chemogenetic gene therapy that targets opioid circuit in ACC without addictive properties @flybottleescape.bsky.social @cmu-neuroscience.bsky.social @cmu.edu www.nature.com/articles/s41...

New preprint from the lab! 🚀 We find that hippocampal OLM interneurons provide a circuit-level inhibitory feedback signal that dynamically controls when and where behavioral timescale synaptic plasticity can occur. Feedback welcome!

Here's another, showing raw voltage throughout the dendritic tree, the virtual reality location of the animal, the mouse-eye view, and the voltage at the neuron's soma.

New study on axon initial segment plasticity by Chloé Benoit and Dan Ganea. Using a deep brain imaging approach, we find that AIS length changes dynamically during associative learning. Thank you to the wonderful team and collaborators who made this work possible. www.nature.com/articles/s41...

Just in time for Xmas! Check out some new work from my lab looking at noise-invariant representations in excitatory cell-types! Congrats to Tommy Suarez-Omedas! www.biorxiv.org/content/10.6...

Sequences are everywhere! In every brain region. And are written in stone. Invariant Activity Sequences Across the Mouse Brain. Out today, by Célian Bimbard, with @kenneth-harris.bsky.social. Based on data by Célian and by @intlbrainlab.bsky.social. www.biorxiv.org/content/10.6...

BonnBrain 2026 is officially sold out! Last admission decisions will be sent soon. Thank you for the overwhelming interest! We are looking forward to a fantastic meeting in Bonn next March.

My first paper just got published last week! *Longitudinal tracking of neuronal activity from the same cells in the developing brain using Track2p* elifesciences.org/articles/107...

🎉 New Year New LOOPs webinar Join us for our January webinar with Shizuko Hiryu from @doshishauniversity.bsky.social and see how bats “see” with sound and how their biological sonar inspires both biology and engineering. 🦇🧠 🗓️ January 21st ⏰ 10:30 AM CET 📍 Register: www.crowdcast.io/c/loops-semi...

New preprint from the lab! A frontal motor circuit for economic decisions and actions: www.biorxiv.org/content/10.6... We use a novel task in mice, cortex-wide imaging and optogenetics, NPX recording and modelling to reveal a circuit mechanism that transforms abstract decisions to spatial actions.

A neuron type-specific microexon in Ank3/ankyrin-G modulates calcium activity and neuronal excitability www.biorxiv.org/content/10.6...

🧠 We're hiring! 🧠 Are you passionate about neuroscience and education? Join our faculty at UNC Chapel Hill to inspire and teach the next generation of neuroscientists. Apply now: 🔗​​https://unc.peopleadmin.com/postings/308455 #Neuroscience #TeachingJobs #AcademicJobs #HigherEd

Today we honour the memory of Adam Kampff, whose passing leaves an immense void in our community. We are profoundly grateful to Adam. The best way to honour him is to continue innovating, collaborating, and sharing generously, as he taught us. Thank you, Adam Kampff.