New preprint with @lingqiz.bsky.social: Neurodata Without Boredom: Benchmarking Agentic AI for Data Reuse arxiv.org/abs/2605.12808 1/10

Excitatory synapses onto axonic spines jump-start action potentials and route information flow www.nature.com/articles/s41...

Upholding #AcademicFreedom is essential to ensure #Europe 's competitiveness and democratic resilience. Joint Statement of the G6 network of #research organisations ➡️ www.helmholtz.de/assets/g6/Do... #demogracy w/th @helmholtz.de @leibniz-gemeinschaft.de @maxplanck.de @cnrs.fr @csic.es

🧠We offer 1-2 Postdoc positions in Circuit Neuroscience!🧠 Join us at @dandrite.bsky.social to study thalamic circuits for visual processing, funded by an ERC starting grant and the Lundbeck foundation. Deadline: 14. Juni 2026 Apply here: international.au.dk/about/profil...

Rethinking hierarchy: the auditory system as an integrated cortical–subcortical network — a Review by Michael Lohse, Ben D. B. Willmore & Andrew J. King #neuroscience #neuroskyence www.nature.com/articles/s41...

NE release is very dynamic, tied to changes in behavioral state, and multimodal, with transient peaks of NE release. High-density electrophysiology paired with dual color imaging revealed that population activity and the firing of individual cortical neurons are strongly modulated around NE peaks.

Neurodata Without Boredom: Benchmarking Agentic AI for Data Reuse arxiv.org/abs/2605.12808

New paper from the lab. Using longitudinal ca imaging, activity-dependent tagging and optogenetics, we show that newly allocated fear engram neurons in amygdala undergo a brief period of coordinated “offline reverberation” immediately after learning. www.pnas.org/doi/10.1073/...

Shared early impairments of medial entorhinal cortex function across distinct Alzheimer's disease etiologies https://www.biorxiv.org/content/10.64898/2026.05.09.723018v1

happy to share our new protocol paper on wildDISCO for whole-body immunolabeling, tissue clearing & 3D imaging of intact mice at cellular resolution using standard IgG antibodies, for mapping of neuronal, vascular, lymphatic and immune systems across the entire body. www.nature.com/articles/s41...

You know GABA as an inhibitor, but that’s not all! We found that tonic GABAergic signaling, mediated by SST-interneurons and alpha5-type receptors, paradoxically facilitates dendritic calcium signals! www.sciencedirect.com/science/arti...

🚨Exiting new preprint from Lerner Lab postdoc AJ Miller-Hansen examining the thalamus as a physiological driver of local, acetylcholine-dependent dopamine release! 🚨 DA-ACh interactions have been 🔥but what’s really going on in vivo? We think we have some answers. #neuroskyence🧪

Coordinated Representational Drift Across the Mouse Cortex https://www.biorxiv.org/content/10.64898/2026.05.05.723038v1

1/10 When the going gets tough, the dendrites get going. Here is a summary on our new paper just published in @science.org on flexible learning in frontal motor cortex. With @mattlark.bsky.social 🔬. #neuroskyence #neuroscience 🔗 doi.org/10.1126/scie...

Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum

What happens when science is free to ask any question? It leads to discoveries we didn’t plan for – but now depend on. This #EuropeDay, we support #ProtectWhatMatters, celebrating the freedom that makes frontier research possible. Read the stories 👉 buff.ly/SRCDWoW and have a happy Europe Day! 🇪🇺

Really pleased that this work with @dudman.bsky.social is now out in Neuron: A global dopaminergic learning rate enables adaptive foraging across many options

Plasticity and language in the anaesthetized human hippocampus www.nature.com/articles/s41... Demonstrates the persistence of oddball discrimination, semantic processing & online prediction in individuals under general-anaesthesia-induced loss of consciousness ->complex processing when unconscious

How did singing mouse evolve its song? Two research manuscripts published today shed light on peripheral and central circuit modifications underlying this novel vocal capacity.

We tracked mice in space! This video shows our estimate of their self-induced centripetal force during circling in 3D 👩‍🚀 Preprint thread below 👇

Automated behavioral segmentation and markerless pose tracking of mice during spaceflight https://www.biorxiv.org/content/10.64898/2026.04.30.721950v1

NPY+ Interneurons in Basolateral Amygdala are Activated by Aversive Stimuli https://www.biorxiv.org/content/10.64898/2026.04.30.722047v1

Sharing the latest from the lab. Led by Yunlong Liu, this work explores how microglia and engram neurons interact during fear extinction in the hippocampus. rdcu.be/fgNH7

Aging Impairs Temporal Integration in Supragranular but Not Thalamorecipient Layers of Primary Auditory Cortex https://www.biorxiv.org/content/10.64898/2026.04.30.722032v1

Multimodal alignments of in vivo imaging and spatial biology datasets at cellular resolution www.biorxiv.org/content/10.6...

PinkyCaMP: a red genetically encoded calcium indicator with improved brightness and stability. @massecklab.bsky.social www.nature.com/articles/s41...

A dataset of simultaneous two-photon calcium imaging and auditory discrimination behavior https://www.biorxiv.org/content/10.64898/2026.04.28.721534v1

Thalamic Nuclei Functional Controllability Explains Cognition Over and Above Grey and White Matter Structure https://www.biorxiv.org/content/10.64898/2026.05.01.722231v1

Check out the birghtest star in the room: PinkyCaMP - the latest member to the red GECI family! Amazing work led by Olivia Masseck and a wonderful team! Proud to contribute

Finally online @natmethods.nature.com www.nature.com/articles/s41... This was a fun collaboration with @finkryan.bsky.social @massecklab.bsky.social @tpatriarchi.bsky.social @martinfuhrmann.bsky.social @campbell-lab.bsky.social @jangrundemann.bsky.social 🧪🧠🔬🧬

Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres! The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!

How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social

Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1

How do the basal ganglia turn what you see into what you do? New preprint w/ @kenneth-harris.bsky.social, @flickerfusion.bsky.social & @carandinilab.net: we recorded across striatum, GPe & SNr in a Go/NoGo task. Striatum encodes which stimulus, GPe & SNr encode action. 🧵 biorxiv.org/content/10.6...

www.nature.com/articles/s41... Two-author papers are always special. Using optogenetic stimulation of hippocampal synapses in awake mice and tracking them over approx. 2 weeks, we link synaptic strength, spine volume and their stability. It's confirmed: bigger spines are stronger and more stable 😅

Cortical inhibitory potentiation reverses maladaptive amygdala plasticity after noise-induced hearing loss https://www.biorxiv.org/content/10.64898/2026.04.02.716147v1

Excited to share our recent review, which highlights algorithmic and implementational degeneracy in studies of cognition: www.sciencedirect.com/science/arti...

Excited to share a new paper from our lab, just in time for Easter, where we characterize how arousal modulates different excitatory cell-types in the auditory cortex! www.science.org/doi/10.1126/...

Our paper is out today!!! (not an April fool's day joke) Congrats to authors @azulsilva.bsky.social, @belalima-paiva.bsky.social, Ele Pronier, and mostly to the amazing scientist and human being who led this project @facuumm.bsky.social #neuroskyence #hippocampus www.nature.com/articles/s41...

Very excited to share new work by Leonardo Lupori. In mice, a single dose of the antipsychotic clozapine results in changes to behavior and cortical activity patterns that remain detectable a week later. www.biorxiv.org/content/10.6...

Open Research Europe is stepping into an exciting new chapter to become a truly collective European diamond open access platform: Backed by 16 national funders and research institutions and continued European Commission involvement, ORE will be hosted by CERN in Geneva. home.cern/news/news/kn...

Incredible conference👏🧠 thank you for everything.

Excited to share our new J Neurosci paper showing how subcortical inputs are routed through ventromedial (VM) thalamus to layer 1 interneurons in the medial PFC, all done by my graduate student Sanne Casello: sannemcasello.bsky.social www.jneurosci.org/content/earl...

A great start to #BonnBrain26 🧠 today, highlighted by the excellent young investigator talks by @martipof.bsky.social, @samueleckmann.bsky.social, Nicole Hoffmann, Carlo Castoldi, Karen Yu Chen Cheng, @seidlcarina.bsky.social, @j-b-eppler.bsky.social and Julia Schnermann 💫💪 #DZNE #BonnBrain

New preprint! Follow the thread to find out about the exciting work of an outstanding postdoc in my lab @merylneuro.bsky.social !!!

We are at #BonnBrain26! Find us tomorrow at the poster session to chat about smelling delicious things and then eating them, and how what is delicious and what you eat may evolve! #celegans #worms #pharynx

Don’t miss our lab’s posters at @bonnbrainconf.bsky.social, featuring exciting new work from Eva Sebastian, @paricio-montesinos.bsky.social & Ziyan Huang on large-scale neuronal activity in sensory thalamus function, decision-making, sleep & inhibitory regulation. 🧠🔬 @dzne.science #BonnBrain26

Registration and abstract submission for our symposium Naturalistic Neuroscience – from perception to action and back (University of Bonn 28-29 May 2026) is no open! www.nn2026.uni-bonn.de/en/registrat... #NN2026 @unibonn.bsky.social #naturalisticneuroscience #neuroscience #symposium #cfa

Cardiac signals shape insular cortex activity and emotion coding https://www.biorxiv.org/content/10.64898/2026.03.18.712676v1