New preprint from the lab. @markgergues.bsky.social and crew show that the PVT gates ventral hippocampal salience coding, shifting output between threat- and reward-weighted representations during associative learning and anxiety-related behavior. www.biorxiv.org/content/10.6...

vCA1 SST neurons represent avoidance states that guide anxiety-related behavioral choices https://www.biorxiv.org/content/10.64898/2026.03.02.709156v1

Excited to share our new paper: We uncover a locus coeruleus→amygdala circuit linking β-adrenergic signaling to transcription regulation in defined amygdala cells during memory reconsolidation—+ stress or elevated noradrenergic signaling at recall can strengthen memory. www.cell.com/neuron/abstr...

Apply by Oct 15 - please spread the word!

New paper from the lab, from Jeremy Biane and team, out today, characterizing the principles of stimulus feature coding in populations of ventral CA1 neurons.

New work! Learning is assumed to involve synaptic plasticity, but which specific synapses change to enable higher order cognitive functions? We actually find that cognitive flexibility involves potentiation of long-range GABAergic synapses from prefrontal PV neurons: www.biorxiv.org/content/10.1...

Come to our symposium tomorrow morning at #NeuroFrance2025 if you want to hear about extero- and interoceptive impact on emotions!

I’m excited to share a new paper from the lab. The study led by Xiaowei Gu reveals how the mPFC encodes complex emotional memories, using an internal model to infer emotional associations and memories via projections to the amygdala. a🧵(1/8) rdcu.be/el19t

Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation. rdcu.be/el18q A short thread follows for those interested. 1/n

A much-needed joint effort from five labs to see which behavioral effects of psilocybin in mice are reliable, and which may be spurious 🐁🍄 @theborislab.bsky.social @mazenkheirbek.bsky.social @indigenerd.bsky.social Vikaas Sohal and Stephan Lammel 👏 www.biorxiv.org/content/10.1...

Excited to share our latest story! We found disentangled memory representations in the hippocampus that generalized across time and environments, despite the seemingly random drift and remapping of single cells. This code enabled the transfer of prior knowledge to solve new tasks

🚨📃New Wassum Lab Paper📃🚨 Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇 www.nature.com/articles/s41... Free full text: rdcu.be/eaxEv

For our inaugural post on bsky, we're happy to share our preprint on tardigrades as a new model organism for neuroscience. Exciting times for these little critters! www.focolab.org/post/our-pre...

Scientist position at The Hospital for Sick Children in Toronto. We are looking for neuroscientists with interests in the molecular and cellular bases of cognition. The position is open-rank, and the successful candidate will also be appointed at U Toronto. Deadline is Feb 15th. Come join us!

Check out our pre-print from Xiaowei Gu! It shows how the medial prefrontal cortex encodes an internal model of emotional associations which can be used for inference biorxiv.org/content/10.1...

𝗨𝗻𝗱𝗲𝗿𝘀𝘁𝗮𝗻𝗱𝗶𝗻𝗴 𝘁𝗵𝗲 𝗻𝗲𝘂𝗿𝗮𝗹 𝗰𝗼𝗱𝗲 𝗼𝗳 𝘀𝘁𝗿𝗲𝘀𝘀 𝘁𝗼 𝗰𝗼𝗻𝘁𝗿𝗼𝗹 𝗮𝗻𝗵𝗲𝗱𝗼𝗻𝗶𝗮 Looks like a very cool paper. #neuroscience doi.org/10.1038/s415...

A beautiful work with a wonderful team! A lot of new ideas and a huge number of elegant experiments

Excited to share our new paper out now @natureportfolio.bsky.social, where we identified neural signatures of stress susceptibility and resilience in the amygdala-ventral hippocampal network to enable control of anhedonia! <https://www.nature.com/articles/s41586-024-08241-y> Thread below:

What is the neural code and statistical structure of neural states characterizing stress? Our new work in Nature answers these questions and more. Thanks to my amazing co-first @fxia.bsky.social @stefanofusi.bsky.social @mazenkheirbek.bsky.social for precious guidance www.nature.com/articles/s41...

I am excited that my first Bluesky post is to share our new paper in @natureportfolio.bsky.social - "Understanding the neural code of stress to control anhedonia." With @fxia.bsky.social , @valeriafascianelli.bsky.social and @stefanofusi.bsky.social. www.nature.com/articles/s41...