Our Editor-in-Chief Dan Gorelick will be attending #CellBio2025 @ascbiology.bsky.social @embo.org. Come and visit Dan @danielgorelick.bsky.social to discuss Biology Open, our Fast & Fair peer review initiative and other @biologists.bsky.social initiatives.

If you’re at #CellBio2025, please do reach out if you’d like to find out more about publishing in @jcellsci.bsky.social (and if you’re not, here’s a list of reasons for why you should choose JCS: journals.biologists.com/jcs/pages/re... 😁)

Bummed to miss #ASCB this year (one of my fav meetings), but the lab is well represented! Stop by poster B169 today and Maneesha will tell you all about her work on basal bodies and cilia homeostasis in multiciliated cells 👇 #CellBio2025

Our Editors will be attending #CellBio2025 @ascbiology.bsky.social @embo.org. Reach out to @seemagrewal.bsky.social and Amelia Glazier to discuss JCS, @focalplane.bsky.social and our other @biologists.bsky.social initiatives.

Thrilled to share our work on the 🔥 single-celled predator Podophrya collini, which rewires its cell morphology to hunt more efficiently. Huge thanks to our amazing team—Amy, Lauren, Omaya, Marine, Mari, and especially Scott—for making this shine! ✨

Exciting new findings on mechanisms of Wnt signalosomes --from Sheng-yuan Wu's PhD project in @matthias-krause.bsky.social lab! Great collaborators, great story. #xenopus 🐸

We’re excited for the UK Cilia and Centrosome Network e-symposium this afternoon featuring the #JCSciliaSI! To discover more about the research in this issue, check out these JCS snapshots, video highlights from authors about their research: focalplane.biologists.com/2025/11/24/j...

An outstanding opportunity. @ukcilianetwork.bsky.social could amplify this (maybe they have)?

Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526

I saw her at the poster session at ASCB 2024! very very impressive work and such a cool model system to study.

Key transcripts encoded centrin-like proteins, a frequent component of sensory/contractile structures in protists. We visualized tentacle ultrastructure by U-ExM with @dudinlab.bsky.social lab, discovering stunning tip and collar structures 🤯that add structural complexity to new tentacle formation.

Thanks for the shoutout! @jcellsci.bsky.social :)

While trying to steer clear of the ‘best organelle’ debate, we’re delighted to highlight #JCSciliaSI, guest edited by @cilialab.bsky.social & @lottepedersen.bsky.social. And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!

Rudolfo Karl, Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social and colleagues discover that renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease. #JCSciliaSI journals.biologists.com/jcs/article/...

Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase. www.nature.com/articles/s41...

If you’re at #sfn25 you definitely don’t want to miss this nanosymposium on cilia, tomorrow from 1-4pm! Come learn about neuronal cilia, they do some pretty cool stuff!

In an eight-person rowing boat, each rower contributes to movement but also has a unique role: balancing, powering, or setting the rhythm and pace. In our latest collaborative work we asked – do the eight dynein “rowers” in #cilia and #flagella operate in the same way?

Very excited to share this one! Our comprehensive structure, genetics and biophysics dissection of which flagellar dyneins and other proteins are needed for flagella to beat and drive cells swimming behaviours: www.biorxiv.org/content/10.1...

Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together. Happy reading! #cilia #flagella journals.biologists.com/jcs/issue/13...

Amanda Smith, Lawrence Ostrowski and colleagues find that lipid nanoparticle-encapsulated Dnai1 mRNA rescues ciliary activity in primary ciliary dyskinesia mouse cell models. #JCSciliaSI journals.biologists.com/jcs/article/...

Laurence Wilson and Martin Bees use high-speed 3D holographic imaging to capture the flagellar beat of single algal cells, revealing changes in the ‘handedness’ of the flagellar shapes at different points in their cycle. #JCSciliaSI journals.biologists.com/jcs/article/...

Exciting project!

This was a fun chat. Thanks @jcellsci.bsky.social for featuring me and spotlighting our work. Check out the special issue on Cilia and Flagella journals.biologists.com/jcs/issue/13.... We have an article on Axonemal Dynein Assembly Factors (DNAAFs) which may be useful for the field.

📣 Here it is — our overview on ciliary proteomics! Great discussions and writing with @mick-lab.bsky.social and Ronald Roepman 🙏🙏 Hope we didn’t miss anything important - apologies if we did! #cilia #ciliopathies #proteomics @theracilproject.bsky.social @for5547.bsky.social tinyurl.com/yc8ztn5v

Great Science! Great food and great company in Oberbronn! Thank you to the organizers of the CFC meeting 2025! Thank you for all the fantastic talks & posters! + unbeatable morning runs! @club-cfc.bsky.social @bastinlab.bsky.social @alexbnmrh.bsky.social #cilia #flagella #centrosome #ciliopathies

Our Special Issue on Cilia and Flagella: from Basic Biology to Disease, guest edited by @cilialab.bsky.social‬ and @lottepedersen.bsky.social, is building. We’ll be highlighting all the articles over the next couple of weeks. Follow along at #JCSciliaSI. journals.biologists.com/jcs/issue/13...

Great issue! Bonus: includes Daniel's work on incorporation of tagged tubulin in flagella!

Thank you @bastinlab.bsky.social and Sylvie Friant for organising this amazing #cilia meeting! 🙏 So many interesting discussions, and not enough time! Just look at this beautiful venue... 🤩

Many thanks to all participants to the CFC2025 meeting last week for having made it such a vibrant experience! So much exciting research on #cilia

Special thanks to our keynote lectures for fantastic talks! @micromotility.bsky.social @mick-lab.bsky.social

Thank you to the organizers of the CFC meeting 2025 in Oberbronn! See you next year in Lyon! @club-cfc.bsky.social

Synapses may get all the glory, but join us cilia-philes for our @sfn.org Nanosymposium to learn about the role of cilia in modulating brain activity, behavior, and development. Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!

🎆 Join us for an unmissable finale to 2025! 🎆 We're thrilled to bring our #cilia & #centrosome community together 25/11/2025 15:00-17:45 GMT! Our 53rd @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposium schedule is live: www.eventbrite.co.uk/e/bscb-genso... /1

#GEF25 Concluding Plenary Lecture with the wonderful Virginie Hamel.

Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia. Open access link below: www.nature.com/articles/s41... Here's a cool animated summary

Exciting new work on the activation mechanism of the dynein motors that power motile ciliary beating!

Thank you @jcb.org Cynthia and Yameng for this commentary on our IFT paper!

#ExM turned 10 this year - just like #NanoTag! 🎉 Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging. See you in Göttingen! #GEF25

We've had a very active summer of Cilia and Centrosome science! We had our Annual Network meeting in London this year organised by Prof. Hannah Mitchison and Dr. Dagan Jenkins. Meeting highlights are now available to read on the network website. www.cilianetwork.org.uk/events/annua...

Be our new colleague! 🎉 The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor. 👉 More details here: lnkd.in/e8Z9eAm4 👉 Our department: mocel.unige.ch Please feel free to share this opportunity with your network.

New pre-print on the role of CCDC103/DNAAF19 in dynein assembly highlighting it's link to PCD. www.biorxiv.org/content/10.1...

We have a postdoc opening for a protistologist with biophysics inclinations to join our @hfspo.bsky.social project! (focus will be on characterising the morphology, ultrastructure and behaviour of excavates) #protistsonsky Apply by Sept 17th (RTs appreciated!) jobs.exeter.ac.uk/hrpr_webrecr...

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia: Current Biology www.cell.com/current-biol...

The Dunn School PhD programme is live! 🎉 Two projects in our labs: 1) How the motor protein giant dynein-2 works 2) How signalling-essential membrane proteins get into cilia Cryo-EM/ET, single mol & live-cell fluor microscopy, CRISPR-based genetic tools & more! www.path.ox.ac.uk/study-with-u...

The annual Dunn School DPhil studentship competition for 2026 is open for applications. We have a project aimed at understanding the molecular mechanisms of ciliary dynein transport. See details below and please pass on to anyone who might be interested. www.path.ox.ac.uk/project/mech...

PCD Foundation On The Move 2025 kicks off in Minneapolis. President Michele Manion welcomes an audience of 200! Exciting times ahead for #PrimaryCiliaryDyskinesia- registries, clinical trials and more! #OTM2025

Incredibly powerful patient panel to counter narrative that PCD is mild- importance of advocacy for care for their own health in a system where PCD is under appreciated. Burden of airway clearance & toll of school, family & work. Trade-offs choice of nebs, commitments & health trade-offs. #OTM2025

Excited to see this work published online at @cp-cell.bsky.social today! www.cell.com/cell/fulltex...

Great teamwork by the @wachtenlab.bsky.social @masslab.bsky.social and the May-Simera lab in our #FOR5547! Congratulations to the whole team!

With a combination of FIB-SEM, super-resolution & expansion #microscopy, Araujo Alves, Bastin et al @bastinlab.bsky.social @pasteur.fr reveal how IFT trains are progressively restricted to a limited number of #microtubule doublets in the flagellum of T. brucei. rupress.org/jcb/article/... #Cilia