bioRxiv Biochemistry
@biorxiv-biochem.bsky.social
📤 1663
📥 0
📝 4646
DUCs are C2 domain containing plant-specific deubiquitinases stabilizing endocytic cargo at the plasma membrane
https://www.biorxiv.org/content/10.64898/2025.12.04.692294v1
about 3 hours ago
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Toward Site-Specific Characterization of Structural Perturbations on Glycosylated Fc Using NMR at Natural Abundance
https://www.biorxiv.org/content/10.64898/2025.12.03.692071v1
about 23 hours ago
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Hypofucosylation promotes pertussis toxin binding to cell surface glycococonjugates and pertussis toxin-induced intracellular ERK signaling
https://www.biorxiv.org/content/10.64898/2025.12.03.692184v1
about 23 hours ago
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Artemisinin-Conjugated Phototheranostic Probe for Golgi-Targeted H2O2 Detection and Side Effect Attenuation
https://www.biorxiv.org/content/10.64898/2025.12.02.691769v1
1 day ago
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G-quadruplex sequence dictates tau oligomerization and fibril morphology
https://www.biorxiv.org/content/10.64898/2025.12.02.691785v1
1 day ago
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Beyond SOx: Mining Sulfur Bacteria Produce Less Acid due to Unidentified Enzyme Pathways
https://www.biorxiv.org/content/10.64898/2025.12.01.691697v1
1 day ago
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Structures of tRNA-bound CRISPR-Cas13 reveal universal HEPN RNase mechanisms
https://www.biorxiv.org/content/10.64898/2025.12.03.690598v1
1 day ago
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Mapping the Glycogen Synthase 1 Interactome in Brown Adipocytes
https://www.biorxiv.org/content/10.64898/2025.12.01.691470v1
2 days ago
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From Flux to Function: Extracting Mechanistic Insights from Ion Channels via I-V and I-μ Analyses
https://www.biorxiv.org/content/10.64898/2025.12.01.691660v1
2 days ago
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PDK1: one abbreviation, two kinases, relentless confusion
https://www.biorxiv.org/content/10.64898/2025.12.01.691077v1
2 days ago
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1
Decoding isozyme-specific substrate recognition in protein arginine deiminases by proteome-wide citrullination mapping
https://www.biorxiv.org/content/10.64898/2025.12.01.691579v1
2 days ago
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MALDI-TOF mass spectrometry and proteomics as phenotypic screening tools for anti-inflammatory drugs
https://www.biorxiv.org/content/10.64898/2025.12.01.691706v1
2 days ago
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Structural mechanisms of drebrin-mediated F-actin network modulation
https://www.biorxiv.org/content/10.64898/2025.12.01.691618v1
3 days ago
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Targeted Nanoparticles: an Innovative Modality in the Treatment of Cancer
https://www.biorxiv.org/content/10.64898/2025.12.01.691687v1
3 days ago
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Targeting Pleiotrophin to mitigate high fat diet-induced liver metabolic disease: Insights into sex-specific metabolic protection.
https://www.biorxiv.org/content/10.64898/2025.12.02.691898v1
3 days ago
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A guide RNA repeat checkpoint steers CRISPR-Cas9 catalysis
https://www.biorxiv.org/content/10.64898/2025.12.02.691602v1
3 days ago
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Mosquito Ferritin: A Haem-Binding Iron Store Required for Egg Development and Targetable for Malaria Control
https://www.biorxiv.org/content/10.64898/2025.12.01.691523v1
3 days ago
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Splicing factor proline- and glutamine-rich (SFPQ) protein causes transcriptional repression of SNAIL to counteract TGF-β signaling
https://www.biorxiv.org/content/10.64898/2025.12.01.691266v1
3 days ago
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Splitting Hairs: Optimized Sample Preparation Strategy for Mass Spectrometry Imaging of Nematode Caenorhabditis elegans
https://www.biorxiv.org/content/10.1101/2025.12.01.691628v1
4 days ago
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Engineering an Anaerobic Microenvironment to Empower Hydrogenase-Catalyzed Hydrogen Therapy for Diabetic Wound Healing
https://www.biorxiv.org/content/10.1101/2025.12.01.691506v1
4 days ago
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Covalent Reprogramming of Kinase Binders to Modulate Protein Homeostasis
https://www.biorxiv.org/content/10.1101/2025.11.30.691461v1
4 days ago
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RNA interactions drive structural and functional diversification of alpha-synuclein fibrils
https://www.biorxiv.org/content/10.1101/2025.11.30.691421v1
4 days ago
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Splice Isoform Induced Selective Inhibition of Vesicular Monoamine Transporter Assembly Revealed by Multi-level Combinatorial Analysis
https://www.biorxiv.org/content/10.1101/2025.11.29.691296v1
5 days ago
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ClpK as a Chaperone Hub: Computational Exploration of its Protein Interaction Landscape.
https://www.biorxiv.org/content/10.1101/2025.11.28.691151v1
5 days ago
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Computational Repurposing and Phytochemical Screening of Inhibitors Against ClpK from Klebsiella pneumoniae.
https://www.biorxiv.org/content/10.1101/2025.11.28.691150v1
5 days ago
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A dynamical-nonequilibrium molecular dynamics (D-NEMD) alanine scanning approach for identifying allosteric positions in proteins
https://www.biorxiv.org/content/10.1101/2025.11.29.691197v1
5 days ago
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Butyrate Rescues Cardiac Metabolic Dysfunction in Hypertensive Heart Failure with Preserved Ejection Fraction
https://www.biorxiv.org/content/10.1101/2025.11.28.690152v1
5 days ago
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Deep Red Blood Cell Proteome Defines the Band 3 N-Terminus Interactome as a Regulator of Hypoxic Adaptation via BLVRB-Dependent S-Nitroso Transfer
https://www.biorxiv.org/content/10.1101/2025.11.29.691178v1
5 days ago
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Loss of STARD7 Impairs Mitochondrial Phospholipid Homeostasis and Contributes to Mitochondrial Myopathy
https://www.biorxiv.org/content/10.1101/2025.11.27.691062v1
5 days ago
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Development of a New Approach Method to Monitor and Modify Caffeine Metabolism Correlated to CYP1A2 Expression
https://www.biorxiv.org/content/10.1101/2025.11.27.691042v1
5 days ago
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Biochemical characterization of ABHD14A, an outlying member of the metabolic serine hydrolase family
https://www.biorxiv.org/content/10.1101/2025.11.28.691245v1
6 days ago
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Characterization of the Mitomycin C Resistance Protein McrA
https://www.biorxiv.org/content/10.1101/2025.11.28.691146v1
6 days ago
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Process optimization for enhanced enzymatic nylon deconstruction
https://www.biorxiv.org/content/10.1101/2025.11.26.690883v1
7 days ago
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1
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Single-molecule dynamics reveal ATP binding alone powers substrate translocation by an ABC transporter
https://www.biorxiv.org/content/10.1101/2025.11.27.690960v1
7 days ago
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1
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Unconventional DNA architecture in a dopamine-bound aptamer complex
https://www.biorxiv.org/content/10.1101/2025.11.27.690961v1
7 days ago
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Interaction and co-phase separation of SARS-CoV-2 nucleocapsid protein and human hnRNPA1 and its implications for viral life cycle
https://www.biorxiv.org/content/10.1101/2025.11.28.691101v1
7 days ago
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Structure, function and dynamics of mCoral, a pH responsive engineered variant of the mCherry fluorescent protein with improved hydrogen peroxide tolerance.
https://www.biorxiv.org/content/10.1101/2025.11.26.690718v1
7 days ago
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POLQ variants with aberrant DNA polymerase activity protect against UV-induced cell death.
https://www.biorxiv.org/content/10.1101/2025.11.26.690880v1
7 days ago
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A composition-matching algorithm, MatchIDR, identifies prion-like domains that localize to stress granules
https://www.biorxiv.org/content/10.1101/2025.11.24.690216v1
8 days ago
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Topological adaptation of heliorhodopsins enables exogenous second-antenna acquisition in monoderm phototrophs
https://www.biorxiv.org/content/10.1101/2025.11.27.691015v1
8 days ago
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Effects of cell growth and temperature on mitochondrial physiology of Drosophila melanogaster embryonic cell line
https://www.biorxiv.org/content/10.1101/2025.11.25.690158v1
8 days ago
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Multi-stem-loop constrained library enables accelerated SELEX for aptamers with superior kinetics and affinity
https://www.biorxiv.org/content/10.1101/2025.11.27.690911v1
8 days ago
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Synthesis of stable isotope labeled analogs of phytanic acid for separate and combined tracing of alpha-, beta- and omega-oxidation
https://www.biorxiv.org/content/10.1101/2025.11.24.689497v1
8 days ago
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Experience from an HTS campaign: Investigation of susceptibility and rescue of SARS-CoV-2 nsp3 protease assay from metal contamination
https://www.biorxiv.org/content/10.1101/2025.11.27.690678v1
8 days ago
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TDP-43 controls RNA structure through high affinity lattice interactions
https://www.biorxiv.org/content/10.1101/2025.11.26.690829v1
9 days ago
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Structural basis for ATP regulation of human 5-lipoxygenase
https://www.biorxiv.org/content/10.1101/2025.11.26.690380v1
9 days ago
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GPR17 structure and agonism with small molecules and oxysterols
https://www.biorxiv.org/content/10.1101/2025.11.26.690757v1
9 days ago
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Structural insights into autophosphorylation-mediated heat shock response by the protein-arginine kinase McsAB
https://www.biorxiv.org/content/10.1101/2025.11.26.690658v1
9 days ago
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Structural atlas of Pakpunavirus P7-1 reveals determinants of virion stability and genome ejection
https://www.biorxiv.org/content/10.1101/2025.11.26.690771v1
9 days ago
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NanoBRET Tracer Development for Class I Bromodomain Target Engagement in Live Cells
https://www.biorxiv.org/content/10.1101/2025.11.25.689777v1
9 days ago
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