So, OpenAI, whose entire business model relies on some overhyped dudebros using vast amounts of stolen data and stolen labour, is releasing a specialised GPT for the life sciences. And naming it, apparently without any sense of irony or self-awareness. Rosalind.

I am so excited to share our new findings with you! We provide the structural evidence for a direct protein-to-DNA information pathway, showing how a bacterial enzyme 'reads' its own structure to 'write' DNA. www.science.org/doi/10.1126/...

Creating baby geniuses to thwart the AI threat? (Yes, really.) www.motherjones.com/politics/202... - smart people being really stupid about intelligence

😭 openai.com/index/introd...

The number of grant applications is rising sharply. Our capacity for their evaluation isn’t. ERC President Maria Leptin explains why stricter resubmission limits are being introduced for 2027 calls and what they mean for applicants. 🔗 link.europa.eu/xF7kjc

We’re hiring a Junior Group Leader - AI in immunotherapy - to join our team at the earliest possible date. The position is embedded within my Chair and the Chair of Cellular Immunotherapy (Michael Hudecek), and connected to CAIDAS center for AI. med.uni-wuerzburg.de/fileadmin/03...

Check out our new release on BioRxiv co-lead by @pm-mueller.bsky.social 👉 rb.gy/lnrizk special🙏 to Severine Kunz #MDC @leventallab.bsky.social @andimicroscopy.bsky.social @ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM Are the days of discovering new cellular structures over?? /1

🌟 Postdoc position open at Karolinska Institutet to advance research on healthy aging 🔬 🧫 See here: : lengefeldlab.com Please RT! We are excited for your application 😄 @ki.se @novo-nordisk.bsky.social

Time to get back to science! A new video on network embedding, including how we use them to analyze STRING protein networks! youtu.be/8eBD-TlE56A

We are delighted to announce that Paola Picotti has been awarded the Otto Naegeli prize for biomedical research! otto-naegeli-preis.ch

A benchmark of 100 tasks in computational biology to evaluate agentic systems. The example questions seem narrow in scope but they don't include any bioinformatics skill definitions. Top models already solve 80% of these.

We are hiring a postdoc in computational biophysics and machine learning studies of intrinsically disordered proteins We aim to study the function of IDPs by combining CG MD, ML and bioinformatics in collaboration with @tanjamittag.bsky.social & @rhp-lab.bsky.social tinyurl.com/REWIRE-PD

I posted on LinkedIn about my reflections on the genome, 25 years on. www.linkedin.com/posts/ewan-b...

We launched a new Group Leader vacancy in our Center for AI & Computational Biology - VIB.AI @vibai.bsky.social - with a Professorship at Ghent University. Join us with your most creative AI+Biology research plan! Apply before 31st May vib.ai/en/group-lea...

blog post - State of the lab 13, part of yearly series, tracking our lab's progress in academia. This year I am mostly reflecting back on our slow adoption of DL methods, FOMO of new technologies and anxiety about the use of AI for research www.evocellnet.com/2026/04/stat...

Great piece of work and great to see a Drug X Genotype (a type of GxE!) being shown so cleanly. Hats off to @adamauton.bsky.social and team

AI x BIO 2026, 8-10 June Submit an abstract now! >450 registered last year coursesandconferences.wellcomeconnectingscience.org/event/ai-x-b...

I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...

Super excited to be launching two things today: #RustQC 🦀🧬 and rewrites.bio 🚀 I used AI to rewrite 15 RNA-seq QC tools into a single Rust binary (I've never written any Rust). It ended up being over 60x faster. Here's the story 🧵 seqeralabs.github.io/RustQC/

Two (or more) PhD student positions are open with me in protein structure evolution (using AI). Please apply/spread the word. su.varbi.com/en/what:job/...

I was diagnosed with breast cancer at 34. I had 1 year old and 3 year old, and I was exactly one year into my tenure track position. I still miss my old body. But everything is easy after that. www.nytimes.com/interactive/...

This is excellent, one of my favorite long-form pieces on agentic engineering - includes several non-obvious ways in which leaning on coding agents can catch you out

I will probably be hiring either a PhD or a Postdoc in the near future. If you are interested in deep biochemical history or molecular mechanisms of evolution please get in touch.

📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.

We've spent the last year building something at @humantechnopole.bsky.social that we think is genuinely needed: #AI that works across biological scales and data modalities, not just within them. A thread on what we're doing, why, and who we're looking for. A 🧵... 1/9

"Why is publishing so expensive?" It's a question I hear all the time, so we at @biologists.bsky.social thought we'd try to dispel some of the myths around publishing economics & provide transparency around our costs. Today, we publish editorials in all 5 of our journals - links in the thread below.

AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network [new] ...integrates its implicit structural knowledge with X-ray crystallography and cryo-EM for improved elucidation.

Join us today to hear Matthias Peter in the Physical Properties of the Cytoplasm Series to learn what happens when the cytoplasm turns sour.

Monthly median Received to Accepted time (days) at Nature Genetics

This is either brilliant or scary: Anthropic accidentally leaked the TS source code of Claude Code (which is closed source). Repos sharing the source are taken down with DMCA. BUT this repo rewrote the code using Python, and so it violates no copyright & cannot be taken down!

Big day for proteomics and in good company! Matthias Mann @mannlab.bsky.social @mpibiochem.bsky.social, John Yates and Ruedi Aebersold receive the 2026 GairdnerAwards for transforming how we measure and understand proteins at scale. #SystemsBiology #Proteomics #Gairdner2026

We have updated the yeast AlphaFold3 co-folding map. The 15GB docker also has an updated streamlit app that is more responsive and easier to search through if you want to just browse the results. There will be many false positives ! We added known interactions for those wanting to filter.

The Swiss Institute of Bioinformatics @sib.swiss highlights every year some outstanding outputs from SIB members. Have a look at some of the great bioinformatics research of SIB members from 2025 www.sib.swiss/news/discove...

We are recruiting! We are searching for an exceptional postdoctoral fellow to lead the single-cell phenoscaping efforts of the REWIRE-CAN Cancer Grand Challenge @cancergrand.bsky.social For more information and to apply please visit: www.ucl.ac.uk/work-at-ucl/...

There’s some cool recent research on this phenomenon! It turns out vision language models excel at image benchmarks *even when the actual images aren’t provided,* because the answers are implicit in the questions! arxiv.org/abs/2603.21687

Tune in to our next seminar on April 20 at 3pm CEST! We’ll hear from Prof. Tina Perica (@glukozica.bsky.social) and Isabella Menart (@isabellamenart.bsky.social) Register to attend: tinyurl.com/PMCseminar2 Previous seminars: www.youtube.com/@PMCModularity

It absolutely makes sense but incredibly important to quantify and test. Note that the Chatbots supported AITA posters 50% of the time (telling people they were not the A). And most of those are not edge cases!

I’m so pleased to be named a AAAS Fellow! I remember opening the original email thinking wow, which of my awesome faculty won this nice thing (a perk of being chair is getting emails like that) but it was me! www.washington.edu/news/2026/03...

Professor Trey Ideker has been appointed as the new Director of the Big Data Institute. He has been recognised internationally for his contributions to biology, artificial intelligence, and cancer research. Learn more ➡https://buff.ly/YO3dCyx @medsci.ox.ac.uk

We have two paid internships available in our group starting this summer, suitable for master's / pre-PhD students: - Protein structure search - Promoter variation For full details and how to apply see: www.bacpop.org/jobs/

AITHYRA is recruiting an AI/ML STARTING PI Generative Models, Large Language Models, Agentic AI, Active & Reinforcement Learning, AI-driven Scientific Discovery & Lab Automation, ML-driven molecular simulations... Job Ad: aithyra.at/fileadmin/do... Apply by 30.4.2026 #StartingPI #AI/ML #AITHYRA

AITHYRA is recruiting a LIFE SCIENCE PI We are interested in research questions related to one of our four core disease areas: cancer research, immunological disorders, infectious diseases, neurodevelopment disorders. Job Ad: aithyra.at/fileadmin/do... Apply by 30.4.2026 #StartingPI #LS #AITHYRA

Excited to share our new preprint on gnomAD v4! We present the full analysis of 730,947 exomes — new constraint metrics, improved LoF annotation (LOFTEE-2), LLM-based literature curation, and a unified framework for gene discovery and rare disease diagnosis. www.medrxiv.org/content/10.6...

The Candida Genome Database’s new website is now live! Everything has been entirely rewritten from scratch! A quarter of a century old Perl code (some of which I wrote!) producing HTML 2.0 (😬) is all gone, with modern python in its place, producing modern webpages with JavaScript and CSS to make

Atlas of predicted protein complex structures across kingdoms www.nature.com/articles/s41... www.biopredictnavigator.cn

We’re recruiting new Research Group Leaders. We offer: 🔬 World-class IT infrastructure 🧠 Creative freedom for your research 📊 Access to the world’s most comprehensive open biological data Apply by 11 April embl.wd103.myworkdayjobs.com/en-US/EMBL/j... #ResearchCareers @johnlees.bacpop.org @embl.org

Co-folding of Membrane Proteins and Lipid Molecules Improves Membrane-Protein Structure Prediction Accuracy [new] Providing explicit mem context via co-folding proteins w/ lipids in AF3 preds, addressing implicit env. limits.

File under: neither personal nor professional news but very worth sharing. If it is found to be addictive, it must be found to be inappropriate for children www.nytimes.com/2026/03/25/t...

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...