We often talk about THE whole genome duplication in yeasts, but we find new evidence of additional whole genome duplications in other yeast species! Check out this preprint led by @kylethedavid.bsky.social www.biorxiv.org/content/10.1...

1/ New preprint alert! In collaboration between the Rosen, Redding, Collepardo-Guevara & Gerlich labs, we uncover a surprising principle of chromosome organisation: electrostatic repulsion positions centromeres at the chromosome surface during mitosis. 🔗 doi.org/10.1101/2025...

What could be more exciting than watching Euplotes scurry around under the microscope? How about adding some raptorial predation by supergiant cannibal cells? www.biorxiv.org/content/10.1... Video by Vittorio Boscaro. 1/n

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social

Hello! Very excited to share our latest preprint, which is great news for us but terrible news for any diehard fans of PSNR and SSIM as image quality metrics in microscopy... (1/5) www.biorxiv.org/content/10.1...

I'm excited to announce our new biorxiv preprint, wherein we investigate the evolution of the weirdest genetic locus I've ever seen! Behold the tgr genes of the social amoeba, which mediate self/non-self discrimination during facultative multicellularity 🐅 🧵 1/ www.biorxiv.org/content/10.1...

How does evolution shape ancient cellular processes? Our new paper uncovers the mosaic evolution of conserved and diverging endocytic traits in fungi! www.cell.com/current-biol...

It’s out! The evolutionary origins of yeast point centromeres uncovered! “Ancient co-option of LTR retrotransposons as yeast centromeres” www.biorxiv.org/content/10.1...

📢Excited to share our new paper in Nature Physics @naturephysics.bsky.social: Cooperative hydrodynamics accompany multicellular-like colonial organization in the unicellular Stentor! How do single-celled organisms benefit from teamwork? Let’s dive in! #Multicellularity nature.com/articles/s41...?

My postdoctoral work on the non-canonical role of an autophagy-related protein at the spindle pole body (SPB) is now out in @plosbiology.org (doi.org/10.1371/jour...).

Happy to share our paper’s final version on the evolution, structure, and membrane binding / remodeling of Asgard ESCRT-III proteins! And my first 🦋 post! www.science.org/doi/10.1126/...

Cool paper on evolutionary constraints and trajectories shaping point centromere evolution in budding yeasts by @helsenjana.bsky.social @gautamdey.bsky.social @gsherloc.bsky.social www.biorxiv.org/content/10.1...

Centromere evolution isn't a sudden switch! Our study shows centromere transitions are a step-by-step process driven by a combination of drift and selection. Discover how the kinetochore interface shapes this gradual change in our new preprint 🥳 doi.org/10.1101/2025.01.16.633479 🧵(1/8)

Happy holidays from the #DeyLab and 🥂 to a wonderful 2025! (If you haven’t seen one of our cards before, you’re thinking, oh that’s sort of vaguely unsettling, YES! And we are here for it 😊)

I am excited to share this animation of the budding yeast inner kinetochore. Created for David Barford's lab @mrclmb.bsky.social This DNA-binding protein complex acts as an anchor for the spindles that pull chromosomes apart during mitosis. www.science.org/doi/10.1126/... #blender #animation #b3d

Seeing this community grow and thrive is so exciting and frankly inspiring. Here's my artsy take on the current #SciSky vibes ✨☁️

Haven't seen a yeast pack yet, so I made one! Help the yeast people flocculate, share, and send me your name if you like to be added. go.bsky.app/PyUwqLU

I put together a list of profiles in somehow related subjects of chromosome biology go.bsky.app/KqsM3kd

New preprint! #UExM for >200 microbial eukaryotes, all 1670 volumes available via FIJI/Mobie! Thank you to everyone that made it possible especially Armando and @hiralshah.bsky.social , @gautamdey.bsky.social @centriolelab.bsky.social, and @dudinlab.bsky.social! tinyurl.com/PlanExM1

How do karyotypes evolve? Turns out an intracellular tug of war within the metaphase spindle sets the limits for chromosome number evolution. Excited to see our study out today in Nature Cell Biology doi.org/10.1038/s41556-024-01485-w 1/9

Ever wondered how the mitotic machinery can tolerate large changes in chromosome number? In my first postdoc preprint with @gautamdey.bsky.social @gsherloc.bsky.social & Hashim Reza, we show that spindle architecture is a constraining factor for karyotype evolution doi.org/10.1101/2023.10.25.563899