My lab in the NIH Intramural Program (Bethesda, MD) will be recruiting postdoctoral fellows over the next year with flexible start dates. We work on nanoscale cellular imaging of the plasma membrane and related organelles. Please reach out if you’re interested. www.training.nih.gov/jobs/pdp-053...

Thanks @jcellsci.bsky.social for this opportunity to contribute to your centenary collection with our take on the state of the field - 10 years after its modern reincarnation 🧪🌍 W/ @alebenoit.bsky.social @eelcotromer.bsky.social @fritzlaylin.bsky.social journals.biologists.com/jcs/article/...

Calling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us! We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK! Sign up here: meetings.embo.org/event/26-arc... #ArchaeaSky

🗞️ New preprint from the lab, led by our postdoc Ana Garoña (not on here) in collab with @andreagiometto.bsky.social: “Experimental evolution of cellular miniaturization reveals a mechanism for cell size evolution”, aka: “honey, we shrank the yeasts!” 🎥 www.biorxiv.org/content/10.6...

An 8-nm precise map in live cells, which revealed #actin aster formation by #myosin V-driven transport of #formin. Happy to see this work now out! 😃 In collaboration with @kaksonen.bsky.social lab #yeast #pombe #cell_fusion @biology-unige.bsky.social

Awesome animation about the molecular complexity of endocytosis!

Check out Javi’s discovery of a membrane scission mechanism that is a few billion years old!

How do new centromeres evolve while staying compatible with the division machinery? Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore. 👉 doi.org/10.1038/s41586-025-09779-1

So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth! #protistsonsky 🧵

interesting work revealing differences between evolutionary distant actins! "..... ADP-actin filaments depolymerize faster and are mechanically more flexible in Saccharomyces cerevisiae compared to Schizosaccharomyces pombe. " www.biorxiv.org/content/10.1...

Our work on Naegleria Myosin 2 is out! Naegleria encodes 3 Myo2s which contract its actin network—the first evidence of contractile Myo2 outside of Amorphea. Myo2 is actually widespread in Naegleria's relatives and correlates with fast cell crawling. Read more: www.cell.com/current-biol...

This Halloween, we have a spooky evolutionary story for you. The brainchild of @delaconcepcionjc.bsky.social, Nick Irwin and our fantastic collaborators is now out in @natplants.nature.com www.nature.com/articles/s41... Here’s why I love this work — and why I think you’ll enjoy it too. 👇

🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny. #ProtistsOnSky #SciComm #SciSky www.cell.com/cell/fulltex...

Now Christopher Toret is talking about collective invasion organisations in eukaryotic multicellular transitions. #Multicellverse

PhD or Master's position available for Fall 2026! Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont... Please share!

Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction! Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1 doi.org/10.1101/2025...

Be our new colleague! 🎉 The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor. 👉 More details here: lnkd.in/e8Z9eAm4 👉 Our department: mocel.unige.ch Please feel free to share this opportunity with your network.

How does cell end developmental biology inform our understanding of evolution? Join us for an afternoon of discussion about #cells, #development, #plasticity and #evolution. Zoomlink Sep 25th: lu-se.zoom.us/j/62473328732 Zoomlink Sep 26th: lu-se.zoom.us/j/67411449026 #EvoDevo @biologylu.bsky.social

Next Thursday Sept 25 (4-6pm CET) we have our first #FocalPlaneFeatures together with our #membranetrafficking community! Thanks to all who submitted such exciting abstracts. The final program is out, featuring a keynote by Gillian Griffiths. Register here: focalplane.biologists.com/2025/09/16/f...

hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

Do you know what happens when you touch a carnivorous sundew plant? If the touch is strong and large enough, a cytosolic calcium wave will spread from the site of touch throughout the whole plant, but if you only touch one tentacle (see post below), the calcium wave will be local and less intense.

And quite suddenly the autumn daffodils start blooming…

Allocation of resources among multiple daughter cells. New study from Alison Wirshing, Daniel Lew and colleagues @mit.edu: rupress.org/jcb/article/... #Cytoskeleton #Development

New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵

How do cells keep their #actin “highways” stable?🚦 Our paper @PLOS Genetics reveals surprising teamwork (and backup plans!) between tropomyosin isoforms in yeast. #imaging #cytoskeleton #celldivision This work was brilliantly led by @anubhavdhar.bsky.social @bagyasree.bsky.social t.co/RvUrzad5tL

What could be more exciting than watching Euplotes scurry around under the microscope? How about adding some raptorial predation by supergiant cannibal cells? www.biorxiv.org/content/10.1... Video by Vittorio Boscaro. 1/n

Leaving Barcelona after an exciting week of evolutionary biology at the #ESEB2025 meeting!

Folks going to #ESEB2025 : To help people connect on Bluesky, I've started making starter packs. Here is a first one with the names that were available when I started. Ping me if you want to be included in the next one!

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social

🎓 My team is seeking a PhD student in Biochemistry & Cell Biology at I2BC, Paris-Saclay! 🔬 Study cytoskeletal signaling in collective cell migration 🌍 Fully funded, 3 yrs | 📍 Gif-sur-Yvette, France 🗓️ Apply by Aug 22 via the following link: emploi.cnrs.fr/Offres/Docto...

I set out to review the evolution of eukaryotic intracellular traffic, but along the way a new hypothesis came into focus: maybe the earliest membrane carriers were tubules, not coated vesicles! New preprint: ecoevorxiv.org/repository/v... Here’s the idea. 🧵

Go check out the latest preprint from Giulia Zanetti's lab. @dr-downes.bsky.social used cryo-tomography to directly visualize COPI and COPII coated vesicles in situ at unprecedented resolution in human cells. Amazingly beautiful, rigorous, insightful work. www.biorxiv.org/content/10.1...

I was looking through my old microscopy videos, and found this perfect shot of a macropinosome forming through the collapse of an actin-driven membrane ruffle (cyan). Immediately, CRYI-A (orange) is recruited to the vesicle to finish the job. Still in awe with this process after all those years!

While academic publishing may not be broken, it isn’t built to serve science either. It runs on a chain of perverse incentives, but everything we need to rebuild it is already in our hands. #OpenScience #AcademicSky buff.ly/oSesI1s

How does evolution shape ancient cellular processes? Our new paper uncovers the mosaic evolution of conserved and diverging endocytic traits in fungi! www.cell.com/current-biol...

The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field? That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience A 🧵 1/n

Intersectin and endophilin condensates prime synaptic vesicles for release site replenishment @watanabelab.bsky.social www.nature.com/articles/s41...

Hello microscopy and imaging experts and enthusiasts! We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English). Please apply and/or repost! jobs.unige.ch/www/wd_porta...

We're hiring a postdoc! Join our ActinID project to explore an uncharacterized actin-binding protein. - Background in cell and/or structural biology? - Eager to bridge both fields? Get in touch if you're curious or have questions! #cellbiology #cryoEM #cryoET #actin ista.ac.at/en/job/postd...

One of the most exciting discoveries from our lab so far is now online as a preprint! Read a story on how the ParMR and Min systems started to collaborate to create the CorMR cytoskeleton, which now controls cell shape in multicellular cyanobacteria: www.biorxiv.org/content/10.1...

Membranes are the bags that hold cells together. But, sometimes you need to patch a hole in that bag. Megan King (@luskinglab.bsky.social), Patrick Lusk and I, provide perspective on how proteins contribute to supporting organelle compartmentalization www.molbiolcell.org/doi/10.1091/...

We’re hiring! Join us as a TT assistant professor in quantitative cell biology @UniBE. We’re looking for an experimentalist (bonus: modeling/ML/computer vision). Vibrant research, Alps nearby. 🏔️ Details: shorturl.at/PKUDU DM me with questions! #AcademicJobs #QuantBio #CellBiology

How do cells switch on the actin assembly at endocytic sites? How can this on-switch evolve? Check out our new preprint! www.biorxiv.org/content/10.1...

🚨 JOB ALERT 🚨 We're hiring a Research Assistant – no PhD needed! Join us to explore the molecular mechanisms of receptor sorting in endosomes. Experience in protein expression/purification, cloning & cell culture desired 🧫🔬 Apply now 👉 www.nature.com/naturecareer... #STEMCareers #ResearchJobs

I'm grateful for the Research Council of Finland for granting me the Academy Research fellowship! After getting over the shock I will soon move back to Finland to start as a group leader at the Institute of Biotechnology @helsinki.fi. Looking for a PhD student soon! www.aka.fi/en/about-us/...

Preprint: IntAct-U-ExM enables robust, isoform-specific expansion microscopy of actin networks in yeast and mammalian cells. A cool study led by @anubhavdhar.bsky.social in collaboration with Sudarshan and Deepak Nair. www.biorxiv.org/content/10.1...

Our latest research is out 📄 ! This study provides an interaction map of Sla2 & the regulatory proteins Sla1 & Pan1, predicted by AI modeling & confirmed by molecular biophysics. @lucasdefelipe.bsky.social @meytallandau.bsky.social @emilgustavsson.bsky.social @embl.org @cssbhamburg.bsky.social

ONCE a medicine is approved by the FDA after said clinical trials, that medicine is available. SOMETIMES there are updates to a medicine, like: Adding an enteric coating. Changing manufacturing facility. Making a generic version. Altering a stabilizer. Updating a virus strain in a vaccine. 3/

New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction. A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social! www.biorxiv.org/content/10.1...

OMG IT IS OUT EUKARYOTIC HOPANOIDS DESERVE ALL CAPS www.nature.com/articles/s41...