Check out our new release on BioRxiv co-lead by @pm-mueller.bsky.social 👉 rb.gy/lnrizk special🙏 to Severine Kunz #MDC @leventallab.bsky.social @andimicroscopy.bsky.social @ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM Are the days of discovering new cellular structures over?? /1

Thrilled to share our paper now out in Nature Plants 🎉 We developed a genome-host association (GHA) approach to study pathogen adaptation directly from field metadata by using the originating host cultivar as phenotype. www.nature.com/articles/s41...

We could also say that two @zmbp-tuebingen.bsky.social junior PIs and three @greenrobust.de PIs won the 2018, 2026 and 2027 @biochemsoc.bsky.social awards 😉 We are good at recruiting biochemists! 😄

We are happy to celebrate @mpcontreras.bsky.social winning the @biochemsoc.bsky.social 2027 Early Career Research Award! Mauricio joined TSL as a predoc with @kamounlab.bsky.social, where he did PhD and postdoc before starting his group at @zmbp-tuebingen.bsky.social Congrats Mau!

Our work on chromatin evolution in brown algae is now published in @natecoevo.nature.com! We show that developmentally complex brown algae evolved without epigenetic silencing pathways long thought universal, underscoring why non-model lineages are important to study. www.nature.com/articles/s41...

Bridging the gap between biochemistry and developmental biology, we are excited to announce Laura Lorenzo Orts as a recipient of an Early Career Research Award in 2027! Laura's new lab focusses on understanding the mechanisms that activate mRNAs during early development.

As an emerging leader in plant innate immunity, we're thrilled to present Mauricio Contreras with a 2027 Early Career Research Award! Alongside advocating for Open Science and preprint review, Mauricio's "activation-and-release" and "NLR resurrection" models are already referenced worldwide.

How do “LEGO-like” electron-bifurcating modules combine to drive degradation in BTEX-contaminated ecosystems? Check out our latest preprint, where we use cryo-EM and cryo-ET to reveal how the 1 MDa BCRII complex powers extremely endergonic aromatic ring reduction. www.biorxiv.org/content/10.6...

Stay tuned to our feed today as we announce our 2027 Award winners, celebrating fifteen excellent bioscientists, educators and technicians working in the life sciences! #BiochemAwards

Preprint alert 🚨 (1/10) 🧵 𝘈𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘪𝘴 𝘢 𝘱𝘢𝘳𝘢𝘥𝘰𝘹 𝘪𝘯 𝘱𝘭𝘢𝘯𝘵 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺: It can promote resistance, susceptibility, or restrict cell death 🤯 So what is its actual role? We show it acts as a spatial organizer of immunity across cell types 🌱🦠 #proteostasis www.biorxiv.org/content/10.6...

One of biggest mysteries in biology: how did complex eukaryotic cells evolve from simple microbes? ~1.8 billion years ago, an archaeal cell likely merged with a bacterium to form the first eukaryotic cell, but can we ever find direct evidence of this transformative event? 🦠 🚶‍♂️

#TansleyReview: Fascinating single-cell red algae: models for evolution and adaptation Berger et al. 👇 📖 nph.onlinelibrary.wiley.com/doi/10.1111/... #LatestIssue #PlantScience

I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...

Interested on the evolution of plant-microbe interactions?, the MoRE Lab is open to support MSCA applications. Please, check if you are eligible, send your CV and motivation letter including up to three possible references to [email protected]

New preprint out! 🚀 biorxiv.org/content/10.6... We mapped how septins organise infection in the rice blast fungus—and found they are far more dynamic than previously thought. Thread 👇 #FungalPathogenesis #CellBiology #septins

We are devastated to announce that our colleague and friend Professor Philippa Borrill died over the Easter weekend following a rare immune system disorder (HLH). She was a fantastic scientist, collaborator and mentor, and a close friend to many: www.jic.ac.uk/news/profess...

DM: a simple solution to suppress air-water interface interactions in cryo-EM www.biorxiv.org/content/10.64898/2026.04.02.716008v1 #cryoem

Interesting and important work from the @gittacoaker.bsky.social and Jie Zhu labs. There is so much to learn from spatial analyses of plant-pathogen interactions!

📣 Check out this excellent #Postdoc opportunity @leibniz-hki.de which is part of Marie Skłodowska-Curie Actions #MSCA #COFUND. Consider applying to join my lab if you’re interested in opportunistic infections caused by #Fusarium (research area 5). Call ends 26 May 2026 www.fellows4fungi.eu

I will probably be hiring either a PhD or a Postdoc in the near future. If you are interested in deep biochemical history or molecular mechanisms of evolution please get in touch.

📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.

how it feels to work on a grant proposal rn

Preprint alert! I am extremely happy to finally (!) share our work on the redox-dependent regulation of the CRKs in plants! We integrated high-throughput interactomics, redox proteomics, structural modelling, and genetics to map a ROS-dependent CRK interaction landscape in Arabidopsis.

We have been cooking up this story for a while and we are excited to finally be able to share! Read on if you're interested in whole plant regeneration WITHOUT the application of hormones!

New #preprint 😍‼️ led by 2 incredible postdocs @ninizhani.bsky.social & Ranj Papareddy: transforming #UFMylation from a local ribosome rescue pathway to systems level regulator of mRNA splicing www.biorxiv.org/content/10.6... A short 🧵

What if you could cut out sub cellular structures and measure the proteome? SPEx: Compartment-Resolved Proteomics via Expansion Microscopy–Guided Microdissection www.biorxiv.org/content/10.6... awesome work by Curdin Franziscus, @imcf-lex.bsky.social, @biehli.bsky.social, Alexander Schmidt!

nice comprehensive review on plant cell surface receptors. onlinelibrary.wiley.com/doi/10.1111/...

The GBM #PhDAward was presented to Anuj Kumar for his PhD thesis on the „Structural basis of CO2 fixation and energy conservation in acetogens“ Congratulations, Anuj! #MK2026 @unimarburg.bsky.social

Excited to share our new paper in @natcomms.nature.com ! Here, we present the cryo-EM structure of the Cytc₆:PSI complex from Chlamydomonas reinhardtii👇 www.nature.com/articles/s41...

We sequenced the genome of 'desert ginseng' (Cistanche deserticola) - a leafless parasitic plant that gave up photosynthesis - and found it lost huge chunks of its own genome…but started stealing genes from its host! Thanks to my collaborators Prof Huang + her talented team👏🏻 lnkd.in/evF5iU9G

Today’s @johninnescentre.bsky.social @thesainsburylab.bsky.social Friday seminar is a glimpse into the future with Julia Mahamid, Molecular Systems Biology Unit @embl “Enabling discovery by in-cell structural biology” Hosted by @saskiahogenhout.bsky.social

#PlantJob Are you looking for a place to start your independent group and develop all the amazing ideas you have in mind?, consider this to join us @cragenomica.bsky.social www.cragenomica.es/events/sympo...

🌱 CRAG launches an international call for early‑career researchers! We invite young scientists interested in starting their independent research group at CRAG 📅 Deadline - April 26 Apply now 👉 https://f.mtr.cool/jdwzombrbd

“We still don’t know what’s going on, but we’re having fun on the way.” - @likeyoda1.bsky.social (from @unituebingen.bsky.social) Margot’s keynote explored how cell identity is regulated during plant embryogenesis, from the heart to torpedo stage, through precisely timed asymmetric cell divisions.

Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍. www.science.org/doi/10.1126/... www.youtube.com/watch?v=gFE4...

Our new experimental evolution study across 30+ locations using the plant Arabidopsis thaliana —— we direct "see" adaptation and extinction to different climates at the genetic as it happens! Read it in Science dx.doi.org/10.1126/scie... @ucberkeleyofficial.bsky.social @hhmi-science.bsky.social

Got Genome?

Yesterday in @nature.com, we presented the earliest evidence of dogs anywhere in the world — three puppies that were buried by Stone Age hunter-gatherers in Türkiye almost 16,000 years ago. www.nature.com/articles/s41...

Really happy to share that our paper was awarded Best BOKU Paper 🏆 This project means a lot to me, from the first weird observations to uncovering a new Vacuolar Quality Control pathway. Huge thanks to everyone involved 🙏 If you missed it, here’s the paper: doi.org/10.1038/s414...

Why do intrinsically disordered proteins appear larger than they are in SDS-PAGE? We investigate how sequence properties affect SDS-PAGE mobility using synthetic IDRs. Conclusion: We need to consider both SDS binding and the compaction of protein-SDS complexes. www.biorxiv.org/content/10.6...

Atlas of predicted protein complex structures across kingdoms www.nature.com/articles/s41... www.biopredictnavigator.cn

Now out! We show that TEs can be horizontally transferred between fungal species via Starships. Once transferred, these TEs can become active, changing the genome organization and affecting the lifestyle of the recipient fungus. www.nature.com/articles/s41... @oggenfussursula.bsky.social #TEsky

I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

ECRs, one week to go! Please join us for an exciting event: The Sainsbury Laboratory Summer Conference in Plant-Microbe Interactions for Early Career Researchers 20th – 31st July 2026 Norwich, UK Application deadline: 12:00 BST (UTC +1) Monday 30th March 2026 www.tsl.ac.uk/tsl-summer-c...

Some reflections on #Fungal26 This was a great meeting as always but set against some turbulent times of course, which meant many regular attendees were not present. This thread is mainly for them. However, the proportion of first-time attendees was very high and very international. #Fungal26 1/15

Cryo-electron tomography of appressoria of Magnaporthe introduced by @delaconcepcionjc.bsky.social #Fungal26

Pikobodies - a revolutionary technology to engineer immunity into plants introduced by @JiorgosKourelis from his work in @kamounlab.bsky.social @thesainsburylab.bsky.social and now @imperialcollegeldn.bsky.social #Fungal26