Calling all OrthoFinder users! We’ve just released GLADE, a tool to infer gene gains, losses, duplications, and ancestral genomes across a phylogeny. GLADE runs directly on OrthoFinder results. www.biorxiv.org/content/10.6... github.com/lauriebelch/... (1/10)

1/12 I'm ecstatic to share my preprint on legume NLR tissue expression! We investigated the NLRomes of 28 legumes + 4 outgroups, examining tissue expression across 7 legume species. Paper thread below 🧵👇 @thesainsburylab.bsky.social @itqbnova.bsky.social 🔗https://doi.org/10.64898/2026.01.25.701577

Metabolically regulated proteasome supramolecular organization in situ: Cell www.cell.com/cell/fulltex...

GT, thank you so much again for these 2.5 years! You are amazing colleagues and scientists, and I hope we stay in touch ❤️. I will miss you all.

Check out our new paper in @natcomms.nature.com .com where we used #cryoEM together with biochemical and mutational analyses investigated the cotranslational protein folding by Ssb in yeast. Publication: doi.org/10.1038/s41467-025-67685-6 Check below for the cryoEM centric feed. 👇

Emerging fungal pathogens have detrimental impacts on crops, animals, and humans. This study demonstrates that the fungal transition from saprotroph to opportunistic human pathogen is likely facilitated by adaptive translation. www.nature.com/articles/s41...

🔬 Ribosomes are hands down one of the most intricate molecular machines we know. Huge (for a cellular scale at least) complexes made of long RNAs (rRNAs) and proteins … a lot of different proteins. 1/6 (❗️Sound on!) @narjournal.bsky.social

Thank you @marioncmueller.bsky.social, @binebrumm.bsky.social, Eric Kemen, Yiheng Hu and Thomas Lahaye for this nice common effort on effector diversity. Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution doi.org/10.1371/jour...

This is a very special paper for me. I had the idea of combining transcription factor binding with chromatin in 2016/8. It took some time, but thanks to Fred and Vikas, we can finally share the story in @plos.org Genetics looking at chromatin states in Arabidopsis and Marchantia. #PlantScience

📢 2 PhD Positions Available in Plant Immune Receptor Bioengineering at Imperial College London 🌱 Start: Oct 2026 📅 Deadline: 10 Feb 2026 🇬🇧 UK/settled status only 💰 Fully funded (48 months) ℹ️ Info: shorturl.at/po61I #PlantImmunity #PlantPathology #SyntheticBiology 🙏 Share with interested candidates!

And the 4th paper in this week contribution from our lab tells about ribosome biogenesis in yeast. A follow-up story from our wonderful collaborators in Graz - the Bergler Lab. Structural work was again done by the amazing @lgrundmann.bsky.social: academic.oup.com/nar/article/...

A new webinar series is born - ''MechanoBioTalks - Mechanics, Materials and Living Matter", to bring together and inspire researchers interested in biomechanics, biophysics and biology across different kingdoms of life. Join us! For info and registration visit green-te.nl/activities/

Thrilled to congratulate the newly minted Dr. Allahham on an outstanding viva! Many thanks to collaborators and the examiners for their invaluable support throughout the process. @ottlab.bsky.social @kleinevehnlab.bsky.social @hartman-plantlab.com

Yesterday it was cows using tools, today its penguins using satellite imagery.

And another paper with contribution from us. Here Sascha Amann solved the structure of the BORC complex. Due to its shape it is extremely challenging for cryo EM analysis but still he cracked it. Read the full story spearheaded by the Huber lab in Innsbruck: www.pnas.org/doi/10.1073/...

What can we learn from comparing ~2,000 fungal genomes? Find out about: 🍄evolutionary transitions 🍄lifestyles 🍄genome dynamics 🍄sampling gaps 🍄efforts to uncover the remaining fungal dark matter New review by @jgi.doe.gov's Stephen Mondo and Igor Grigoriev www.nature.com/articles/s41...

I am very happy that I could advice in this great story. Seeing single proteasomes degrade in cells is opens so many interesting possibilities. Check the preprint.

Excited to share our new paper! We developed a method to visualize proteasomal degradation at the single–molecule level in live cells, enabling us to dissect distinct modes of substrate engagement, probe co-factor dependence, and study proteasome–ribosome collisions. www.biorxiv.org/content/10.6...

Congratulations to Tom Dendooven, former postdoc in the LMB’s Structural Studies Division, who has launched his own research group at @viblifesciences.bsky.social His group will study the molecular basis of male infertility using electron cryotomography. Best of luck to you Tom! #LMBAlumni 🎉

LLOMe has long been used to study lysosomal damage, yet how it works has remained a mystery. Using cryo-electron tomography, we show it forms amyloid structures inside lysosomes that mechanically rupture membranes – revealing a new paradigm for lysosomal failure. 🔗 doi.org/10.64898/202... #CryoET

TimeVault transforms vault particles into transcriptome recording devices, which are applied to uncover transcriptional heterogeneity in drug-tolerant persister cancer cells #NBThighlight www.science.org/doi/10.1126/...

🧪Scientists from our Haselbach lab captured how proteins begin to fold as they’re being made. Using cryo-EM, they visualised chaperones guiding nascent proteins on the ribosome: https://www.nature.com/articles/s41467-025-67685-6

Have a look at our new structure of co translational folding in yeast. This is collaborative work initialized by the Rospert lab from the @uni-freiburg.de. Structural work has been done by the amazing @lgrundmann.bsky.social Stay tuned for the next ribosome paper from him, following very soon.

Happy to share the pre-print on GEMMIFER, a novel ERF required for the initiation of gemma in Marchantia. One of the coolest phenotypes that I have ever seen. Congratulations to Yuki and Go, who led this research. #PlantScience @biorxiv-plants.bsky.social www.biorxiv.org/content/10.6...

Check out this animation and thread from @gallegolab.bsky.social on the mechanism of #Exocytosis Truly remarkable work! They did it all! 😱

0/10 🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology Continuum architecture dynamics of vesicle tethering in exocytosis www.cell.com/cell/fulltex...

Exploring shaped focused ion beams for lamella preparation pubmed.ncbi.nlm.nih.gov/41529658/ #cryoem

Join us in Norwich this July for the TSL Summer Conference in Plant-Microbe Interactions! ☀️🌱🧬 Discuss the latest approaches & discoveries in plant health with international keynote and local speakers. APPLY by 30 March '26 ⬇️ Click link for more info www.tsl.ac.uk/tsl-summer-c...

We resolved the molecular architecture of a condensate—inside cells. 🤯 By combining in situ cryoET with multiscale simulations, we show how a single point mutation modifies molecular interactions, shifts the condensate’s material properties, and alters its biological function. Preprint 👇

We are excited to share our new preprint which is now available to read on biorXiv: doi.org/10.64898/202... 🎉🎉🎉

ICYMI: New Online! The mechanistic basis and cellular functions of UFMylation

A good day por powdery mildew research community 😍! We described how virulence on Pm4 resistance gene is controlled but two effectors! Avirulence vs Suppression. Work led by @zoebernasconi.bsky.social, Aline Herger, Pilar Caro and @lukas-kunz.bsky.social 🌱🦠🧬A big thank you to everyone involved

Our new article is now online on @natplants.nature.com! ✨ We identified and characterised AvrPm4 and SvrPm4, a pair of powdery mildew effectors controlling avirulence on the wheat kinase fusion resistance protein Pm4 🌾 check it out ➡️ www.nature.com/articles/s41...

The (Yoav) Voichek lab has opened its gates at the Weizmann Institute, and is actively recruiting students and researchers at all levels - come explore gene regulation and computational genomics in a fun, friendly sprouting lab 🤗🥼⚗️🧪 www.weizmann.ac.il/plants/voichek

Prospective #PhD and #postdocs: if you’re looking for truly cutting-edge projects and an exceptional mentor, look no further. You can thank me later. 😉

With the new year, is my time to say bye to @gmivienna.bsky.social as I move to @zmbp-tuebingen.bsky.social in Tuebingen. I will start my solo Group Leader career as a Emmy Norther fellow. Thanks to everyone that helped on the way. I will be advertising PhD and Postdoc positions soon, stay tuned!

This one was quite the journey! The paper describing the #ChlamyDataset is finally out and on the cover of Mol Cell! This beautiful rendering made by co-author @jessheebner.bsky.social and Holly Peterson shows an instance of mitochondrial fission found in the dataset 😍 [Maybe long thread ahead]

Wei Shi @wshisky.bsky.social & Merle‘s work is online. Wei really pushed this work from scratch and Merle linked it to MLA diversification…3rd (co-)first author paper in her PhD. Very proud PI! And only possible through collaboration with G. Döhlemann, @grandpahiro.bsky.social &, Matt Platre. (1/x)

Biomolecular condensate architecture of an autophagic cargo at molecular resolution in situ https://www.biorxiv.org/content/10.64898/2026.01.07.698105v1

🧵 Just out in Cell after more than 10 years in the making! 🎓 www.cell.com/cell/fulltex... Plants and animals evolve radically different body plans. Do they also operate under fundamentally different molecular evolutionary constraints during organ formation? @cellpress.bsky.social

Finally, research led by @victorsmh6.bsky.social, @marintianava.bsky.social & Anita Bianchi from the Dagdas lab identified CESAR, a key player in plant stress response via selective autophagy. The study was published in Developmental Cell. www.oeaw.ac.at/gmi/detail/n...

Research led by @delaconcepcionjc.bsky.social from the Dagdas group discovered that electrostatic changes cause plant protein Exo70 to break from its original complex and take on new functions in the cell. The study was published in Nature Plants. www.oeaw.ac.at/gmi/detail/n...

Research by @josejulian.bsky.social, Peng Gao & Alessia Del Chiaro from the Dagdas group was published in Nature Plants. They discovered that molecule ATG8 protects plant cells from stress by conjugating with vacuoles upon damage to the cell wall. www.oeaw.ac.at/gmi/detail/n...

🧬 New preprint on fungal effector 🍄🍎 We identify AvrRvi6, the first AVR from Venturia inaequalis. AvrRvi6 is a MAX effector with apoplastic activity, expanding the functional landscape of this major effector family. 📄 bioRxiv: www.biorxiv.org/content/10.6...

Not that this passes without being noticed: The GreenRobust cluster of excellence is officially alive since Jan 1, 2026! Looking forward to at least seven years of exciting science in the field of plant ecology, molecular biology, agriculture and the combination of all these fields. Stay tuned!

At the end of 2024 I did a chronological round up of all the #plantscience in @science.org that year. So how did 2025 pan out? This year, I’m grouping papers thematically instead of chronologically so read on to find out what exciting plant science came out over the last 12 months. (1/22)

🔬 EXPERT VIEW 🔬 In this review, Cox & Czymmek cover the recent developments of expansion microscopy techniques in plant systems and provides examples of their applications in plant biology research. 🔗 doi.org/10.1093/jxb/... #PlantScience 🧪 @kcox-bioguy.bsky.social

Advice I now give to grad students and postdocs in the sciences: Don’t just try to meet and impress senior scientists. They’ll retire soon. Get to know your fellow students - make friends where possible, be colleagues at least. These are the people you’ll be sharing the field with for decades.

Finally, we’ve solved a long-standing mystery: what tintinnid shells are actually made of: A new class of biomaterial formed by remarkable structural proteins unique to tintinnids. A major milestone after 3 years of work! Read about it in our preprint: doi.org/10.64898/202... #ProtistsOnSky