Juan Carlos De la Concepcion
@delaconcepcionjc.bsky.social
📤 1721
📥 1227
📝 141
A carpenter with a hammer Plants, Pathogens and Procrastination Emmy Noether Fellow at ZMBP
reposted by
Juan Carlos De la Concepcion
Sophien Kamoun
1 day ago
Science isn’t just a cost. It’s an engine of economic growth. The UK treats scientific R&D as distinct industry in national accounts. It’s ~0.7% of economy, yet ONS identified it as biggest contributors to GDP growth in May after it expanded by 5.1% vs 0.1% overall
stocks.apple.com/Aa-EfoztMSEi...
loading . . .
UK economy grew by 0.1% in May despite impact of Iran war — The Guardian
Rise in GDP follows a 0.1% decline in April, figures from the Office for National Statistics show
https://stocks.apple.com/Aa-EfoztMSEibk1JqwcAxFQ
0
13
3
reposted by
Juan Carlos De la Concepcion
Trevor A. Branch
1 day ago
Blue whales sing so deep they can't be heard by killer whales! New piece on some work I did...
spacedaily.com/t-a-universi...
loading . . .
A University of Washington researcher published a finding in 2025 that stops you cold: blue whales sing at frequencies so deep that killer whales, their only natural predator, cannot hear them at all ...
A blue whale can send a call through the ocean with a voice deeper than almost any animal sound on Earth. The strange part is not only that other blue whales
https://spacedaily.com/t-a-university-of-washington-researcher-published-a-finding-in-2025-that-stops-you-cold-blue-whales-sing-at-frequencies-so-deep-that-killer-whales-their-only-natural-predator-cannot-hear-them-at-all/
1
62
18
reposted by
Juan Carlos De la Concepcion
Mohammed Khallaf
2 days ago
Our new paper is out in
@nature.com
! We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females! A remarkable mammalian parallel to bees and ants! 🐝🐜
@garyrlewin.bsky.social
youtu.be/enfv3zJrWKM?...
loading . . .
Naked mole-rats are ruled by a queen: this chemical puts her in power
YouTube video by nature video
https://youtu.be/enfv3zJrWKM?si=VmMCHb-0GJmjqzc6
11
187
93
reposted by
Juan Carlos De la Concepcion
Michael Raissig
4 days ago
Our single-cell atlas paper made the cover 🎉 image by
@lbmountain.bsky.social
, showing the mature Brachy epidermis in all its beauty.
#GoBrachy
: yellow is lignin, and blue is cell wall autofluorescence.
add a skeleton here at some point
0
53
15
reposted by
Juan Carlos De la Concepcion
Erik Schäffer Lab
3 days ago
How do plant kinesins work at the single-molecule level? We break it all down in our new review "Plant kinesins: a bottom-up approach - from single molecules to function" published in JXB
@jxbotany.bsky.social
🎉 Check it out:
doi.org/10.1093/jxb/...
#Plant
#Kinesin
#SingleMolecule
#ZMBP
loading . . .
Plant kinesins: a bottom-up approach – from single molecules to function
Abstract. During land colonisation, plants evolved new microtubule structures that have no functional analogues in opisthokonts, namely animals and fungi.
https://doi.org/10.1093/jxb/erag336
1
11
6
reposted by
Juan Carlos De la Concepcion
Pedro Beltrao
3 days ago
Team science preprint, exploring the capabilities and limitations of Alphafold3 across different application areas, including protein-RNA, protein-lipid, ubiquitination,TCR and antibody recognition with
@ninjani.bsky.social
@labvanni.bsky.social
@dgfeller.bsky.social
www.biorxiv.org/content/10.6...
loading . . .
Capabilities, specificity gaps and training-data dependence of AlphaFold3 across diverse application areas
Structure prediction models have moved from single proteins to assemblies that include diverse biomolecules and their modifications. AlphaFold3 (AF3) and related models extended structural modelling v...
https://www.biorxiv.org/content/10.64898/2026.07.13.738147v1
1
44
20
reposted by
Juan Carlos De la Concepcion
Sebastian Schornack
4 days ago
Preprint! How do "friendly" rhizobia build a legume nodule?
@albinteulet.bsky.social
found that some may carry hidden transcription factors - proteins that mimic DNA-binding folds to enter the plant nucleus and rewrite its developmental program.
www.biorxiv.org/content/10.6...
(1/6)
1
51
30
reposted by
Juan Carlos De la Concepcion
Adam Bentham
4 days ago
Excited to see our new preprint on bioRxiv! 🌱🤖 We used AI protein design (RFdiffusion + ProteinMPNN) to build brand-new sensor domains from scratch and installed them in a rice NLR immune receptor engineering recognition of a Fusarium effector FoSSP17
add a skeleton here at some point
2
34
17
reposted by
Juan Carlos De la Concepcion
Matt Gabriele
6 days ago
Hello from academia
add a skeleton here at some point
17
957
108
reposted by
Juan Carlos De la Concepcion
Clausen Lab
5 days ago
www.science.org/doi/10.1126/...
loading . . .
Virome-wide ubiquitin ligase discovery reveals diverse mechanisms of immune evasion
Viruses are intracellular parasites that reprogram the host proteome to promote replication and evade immune recognition. We applied a virome-wide library of ~10,000 open reading frames to discover vi...
https://www.science.org/doi/10.1126/science.aec6299
1
13
4
reposted by
Juan Carlos De la Concepcion
Kasper van Gelderen
8 days ago
Very happy with our
@greenrobust.de
@isabelmonte.bsky.social
Plant Robustness session at the
@sebiology.bsky.social
conference. Excellent talks by
@hildenelissen.bsky.social
, Marcel Quint,
@rsasidharan.bsky.social
and Amy Austin. Great fishbowl discussion on plant robustness! Thanks PlantJ
1
24
8
reposted by
Juan Carlos De la Concepcion
bioRxiv Plant Bio
8 days ago
Defining the Xanthomonas euvesicatoria type II-secreted effector arsenal: core nutritional functions and effector diversity
https://www.biorxiv.org/content/10.64898/2026.06.19.733414v1
0
4
2
reposted by
Juan Carlos De la Concepcion
Ben Barad
8 days ago
cxtoolshed.rbvi.ucsf.edu/apps/chimera...
Available through the toolshed now! Thanks to the chimera team for reviewing this one very quickly.
add a skeleton here at some point
0
14
4
reposted by
Juan Carlos De la Concepcion
Sophia Paul
9 days ago
Excited to share my paper! 🥳 Today in
#Nature
we reveal an 8 MDa Hdr electron bifurcating super-assembly in class I methanogens that couples the first and last steps of hydrogenotrophic methanogenesis. A lineage-specific adaptation to anaerobic niches.
www.nature.com/articles/s41...
loading . . .
3
67
28
reposted by
Juan Carlos De la Concepcion
GreenRobust
9 days ago
How plant stem cells are kept robust summarized by GreenRobust PIs Jan Lohmann (
@meristemania.bsky.social
) and Thomas Greb (
@thomasgreb.bsky.social
). Enjoy!
www.sciencedirect.com/science/arti...
loading . . .
Plant stem cell systems: Robust by design
Plants maintain active stem cell populations throughout their lives, yet these systems are remarkably resilient to genetic, environmental, and mechani…
https://www.sciencedirect.com/science/article/pii/S1534580726002273?via%3Dihub
0
16
10
See the In brief article by Jan Hübbers about our recent publication
@theplantcell.bsky.social
"Baiting blast fungi: An engineered NLR domain improves effector recognition"
academic.oup.com/plcell/advan...
loading . . .
Validate User
https://academic.oup.com/plcell/advance-article/doi/10.1093/plcell/koag189/8710968
9 days ago
0
11
5
reposted by
Juan Carlos De la Concepcion
Sophien Kamoun
10 days ago
We are excited to invite all current and former members of the Kamoun Lab, together with their lab members and our collaborators to the Kamoun Lab Alumni Meeting on Monday, 7 September 2026 ahead of the ECPP and BSPP at the Assembly House, Norwich.
1
17
7
reposted by
Juan Carlos De la Concepcion
Michael Borg
10 days ago
Our group is moving from
@mpi-bio-fml.bsky.social
to the maritime city of Kiel! ⛵️🩵 I will lead the Department of Marine Plant Development and Physiology
@uni-kiel.de
🌱🪸🌊 Look out for opportunities to join us in this exciting & growing hub for Plant, Marine & Evolutionary Biology in North Germany 🇩🇪
11
97
28
reposted by
Juan Carlos De la Concepcion
11 days ago
1/ Happy to share our preprint! The Mtr complex catalyses the second-to-last step of the methanogenesis and is an essential bioenergetic machine in most methanogenic archaea. Anaerobic cryo-EM of Mtr reveals a nitrogenase-like metallocluster bound at its active site!
www.biorxiv.org/content/10.6...
2
31
17
reposted by
Juan Carlos De la Concepcion
bioRxiv Biochemistry
11 days ago
The anaerobic cryo-EM structure of the methanogenic Mtr complex reveals a nitrogenase-like [FeSC] cluster bound to its active site
https://www.biorxiv.org/content/10.64898/2026.07.03.736320v1
0
7
2
reposted by
Juan Carlos De la Concepcion
Felipe Opazo
15 days ago
New paper! 🚀 A high-affinity anti-
#mNeonGreen
#nanobody
turns
#mNG
into a
#multifunctional
Tag.
@nanotag.bsky.social
decided to openly share the
#nanobody
for research use. Not common, but we strongly believe well-defined reagents are key for reproducible science. We hope you find it useful! 💚
5
99
51
reposted by
Juan Carlos De la Concepcion
Danve Castroverde
14 days ago
Surface immune signaling unlocks NLR activation through mRNA alternative splicing
www.science.org/doi/10.1126/...
loading . . .
Surface immune signaling unlocks NLR activation through mRNA alternative splicing
Plants activate pattern-triggered immunity (PTI) and effector-triggered immunity (ETI) to combat pathogens. However, how these systems coordinate immune activation while preventing autoimmunity remain...
https://www.science.org/doi/10.1126/science.adx9929
0
27
14
reposted by
Juan Carlos De la Concepcion
Fenomenoide 🍉☭
14 days ago
6
314
79
reposted by
Juan Carlos De la Concepcion
Chung Hyun Cho
13 days ago
Excited to share our new preprint led by Fred and me in collaboration with the archaeal community! We found that the molecular foundation of histone-based chromatin has pre-eukaryotic roots in Asgard archaea. (1/4)
#ArchaeaSky
www.biorxiv.org/content/10.6...
loading . . .
Emergence of histone-based chromatin complexity in Asgard archaea
The emergence of the eukaryotes coincided with the diversification of histone proteins and their post-translational modifications by enzymes that constitute the core of eukaryotic chromatin. Yet the e...
https://www.biorxiv.org/content/10.64898/2026.07.02.735847v1
7
137
80
reposted by
Juan Carlos De la Concepcion
Max Planck Institute of Biochemistry
14 days ago
#pictureofthemonth
: Plant cells use tiny pores called plasmodesmata to talk to each other. The rendering, shows how everything links together. More:
www.biochem.mpg.de/baumeister-p...
July – Calendar of
@mpiforbi.bsky.social
and
@mpibiochem.bsky.social
📸 by Monika Krause & Marcel Dickmanns
0
7
4
reposted by
Juan Carlos De la Concepcion
Mary Mirvis
2 months ago
1/13 So excited to share our new preprint!! How do organelles pack together in a crowded cytoplasm? we know organelles interact via contact sites, but how does competition for space contribute to organelle morphology and interactions?
@wallaceucsf.bsky.social
www.biorxiv.org/content/10.6..
.
3
83
27
reposted by
Juan Carlos De la Concepcion
Paula Navarro
14 days ago
🚨 New in
@natmicrobiol.nature.com
! We reveal how the antibiotic target PBP1b fortifies the E.coli division site against osmotic rupture. Proud this was completed in our independent labs
@dmf-unil.bsky.social
, with
@avettiger.bsky.social
. Congratulations to all authors! 🦠❄️🔬
#teamtomo
bit.ly/3SCbOg1
👇
loading . . .
The penicillin-binding protein PBP1b fortifies the Escherichia coli division site against osmotic rupture - Nature Microbiology
A specific isoform of PBP1b functions independently of the activator protein, LpoB, to drive generation of a wedge-like peptidoglycan structure that strengthens the division site in Escherichia coli.
https://doi.org/10.1038/s41564-026-02403-6
3
88
34
reposted by
Juan Carlos De la Concepcion
Andrea Vettiger
14 days ago
Excited to see our story published in
@natmicrobiol.nature.com
today! It’s been a long journey. We answered a major outstanding question: why does E. coli encode two aPBPs, yet only one plays a critical role in ensuring reliable PG fortification during cell division?
add a skeleton here at some point
2
44
14
reposted by
Juan Carlos De la Concepcion
EMBL Events
15 days ago
The new edition of #EMBOinsitu takes place in February 2027 and registrations are now open! Submit your abstract by 3 November and join us to explore current and future opportunities for in situ structural biology, with a focus on system-wide approaches 🔬
s.embl.org/iss27-01-bl
0
2
1
reposted by
Juan Carlos De la Concepcion
Andrea Doddi
25 days ago
Thrilled to see this work finally out in Nature Communications!
@natcomms.nature.com
. Thanks again to all the people involved, to
@lfaino.bsky.social
and
@teamthomma.bsky.social
.
add a skeleton here at some point
0
17
5
reposted by
Juan Carlos De la Concepcion
EMBL
17 days ago
📢 Applications are now open for the
#ARISE2
Fellowship Programme! With funding from MSCA, the programme trains scientists to become leaders in Research Infrastructures and innovate in the life sciences. 🧪 Apply here:
www.embl.org/training/ari...
loading . . .
0
5
3
reposted by
Juan Carlos De la Concepcion
Ján Bíňovský
15 days ago
🔥My first (co)first-author paper is out🔥 The surfaces of Gram+ and Gram- bacteria are markedly different from each other. How are phages equipped to breach the Gram+ envelope❓ 💡We report a baseplate structure uniquely adapted to infect Gram+ S. aureus. A 🧵⬇️ 1/8
#phagesky
#cryoEM
🧪
loading . . .
3
57
14
reposted by
Juan Carlos De la Concepcion
International Society for Molecular Plant-Microbe Interactions
16 days ago
Important news! The new ISMPMI website is live! Visit the site to get society news, watch posted videos, listen to our podcasts, become or manage your membership and more.
ismpmi.org
loading . . .
IS-MPMI - International Society for Molecular Plant-Microbe Interactions
Diverse Backgrounds Common Interests Connecting leading scientists and researchers around the world in microbiology, nematology, plant pathology, developmental biology, genetics, genomics, proteomics,...
https://ismpmi.org
0
5
9
reposted by
Juan Carlos De la Concepcion
Svetlana Dodonova
28 days ago
Excited to share our new preprint! 🧬❄️ by brilliant
@mdreimann.bsky.social
and great collaborators! Using cryo-ET&EM, we reveal archaeal chromatin in a near-native state: variable-beads-on-a-string fibers shaped by growth phase and histone composition
#ArchaeaSky
www.biorxiv.org/content/10.6...
loading . . .
8
150
69
Also, come talk to me about the amazing opportunity to access to a miriad of scientific services through Europe thanks to
@agroserv.bsky.social
initiative!
#RBMP2026
agroserv.eu
add a skeleton here at some point
16 days ago
0
0
0
reposted by
Juan Carlos De la Concepcion
Thorsten Langner
16 days ago
‼️Job altert🚨📢 please spread the word: We're looking for a postdoctoral researcher to join our new department "Phytopathology and Plant Protection" at
@unihalle.bsky.social
.
www.verwaltung.uni-halle.de/DEZERN3/AUSS...
3
49
67
reposted by
Juan Carlos De la Concepcion
Haselbach Lab
16 days ago
We're delighted to announce the 9th Austrian Cryo-EM (ACE) Symposium - Sept 24-25, 2026 at IMP, Vienna. Organized with
@istaresearch.bsky.social
🎤 Abstract deadline: Aug 5, 2026 📅 Info & registration:
imp.ac.at/research/cryo-em-symposium/
loading . . .
Cryo-EM Symposium | Vienna BioCenter | cryo-Electron Miscroscopy Conference
The annual Cryo-EM Symposium is a conference for structural biologists to discuss cutting-edge developments in cryo-Electron Miscroscopy. Held at the Vienna BioCenter.
https://imp.ac.at/research/cryo-em-symposium/
0
20
8
reposted by
Juan Carlos De la Concepcion
Instruct-ERIC
16 days ago
New Scientific Highlight! This time focusing on EasyGrid, a system developed by the Papp Team at
@embl.org
Grenoble to allow fully automated sample preparation and quality control for cryo-electron microscopy and tomography.
loading . . .
EasyGrid: an automated cryo-electron microscopy sample preparation instrument
Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to all European researchers.
https://instruct-eric.org/scientifichighlights/easygrid-an-automated-cryo-electron-microscopy-sample-preparation-instrument/
0
7
2
Today marks a major milestone for my lab
@zmbp-tuebingen.bsky.social
. We got our first member! I am really excited to welcome
@d-moser.bsky.social
. She will bring her expertise in cryo-ET data processing to solve the mechanisms of plant invasion by fungal pathogens 🧊🔬🌾🍄 Follow her and stay tuned!
16 days ago
3
75
9
Glad to be attending
#RBMP2026
in Bilbao this week! Very excited about the opportunity to (re)connect with the Spanish plant molecular biology community :D Come along poster S3.P9 to chat about plant structural biology and ribosome dormancy 🌱🧊🔬
16 days ago
0
3
1
reposted by
Juan Carlos De la Concepcion
Tomas Pachano
17 days ago
I am thrilled to share our paper out in
@cp-cell.bsky.social
: "Systematic Discovery of Pathogen Effector Functions across Human Pathogens and Pathways." (1/4)
www.cell.com/cell/fulltex...
loading . . .
Systematic discovery of pathogen effector functions across human pathogens and pathways
The eORFeome, a large-scale collection of open reading frames encoding viral proteins and secreted bacterial and parasite effectors, enables functional genomics across diverse pathways and pathogens. ...
https://www.cell.com/cell/fulltext/S0092-8674(26)00704-X
4
62
21
reposted by
Juan Carlos De la Concepcion
New Phytologist
16 days ago
We're pleased to sponsor the 13th Plant Molecular Biology Meeting, 1–3 July, Bilbao, Spain.
rbmp2026.com/RBMP/en/info
1
5
1
reposted by
Juan Carlos De la Concepcion
Chi-Min Ho
17 days ago
Incredibly proud of Messi Haile
@mehsehret.bsky.social
, a founding member of the Ho Lab, for her beautiful work uncovering the inner workings of a central piece of the malaria parasite invasion machinery: the malarial moving junction, out today in
@cellpress.bsky.social
!
tinyurl.com/4p3md2eb
🦠❄️🔬
4
106
37
reposted by
Juan Carlos De la Concepcion
Nature Reviews Molecular Cell Biology
17 days ago
New Online! Plucking cellular ribosomes with Ribo-Tweezer
loading . . .
Plucking cellular ribosomes with Ribo-Tweezer
Nature Reviews Molecular Cell Biology, Published online: 30 June 2026; doi:10.1038/s41580-026-00998-6In this Tools of the Trade, Chen & Cheng (Barna lab) describe the development of Ribo-Tweezer, a method that enables the targeted degradation of individual ribosomal proteins of the cytoplasmic ribosome.
http://dlvr.it/TTHP7F
0
7
4
reposted by
Juan Carlos De la Concepcion
IMP
17 days ago
Pathogens have spent millions of years learning how to hijack human cells. Now, researchers from the Stark lab at the IMP and the Taipale lab at the Donnelly Centre, University of Toronto, have built a platform to systematically discover how they do it:
1
23
9
reposted by
Juan Carlos De la Concepcion
Drug Monkey
19 days ago
“The biases do not disappear; they get encoded into the model and then laundered into outputs that feel objective because they are numerical. “
add a skeleton here at some point
0
25
6
reposted by
Juan Carlos De la Concepcion
Ran Blekhman
20 days ago
I wanted to like QED's new 1% preprint ranking. I really did. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review.
open.substack.com/pub/blekhman...
loading . . .
My Peer Review of The 1%
I wanted to like QED's new 1% ranking. I don't.
https://open.substack.com/pub/blekhman/p/my-peer-review-of-the-1?r=ptsy3&utm_campaign=post-expanded-share&utm_medium=web
17
207
113
reposted by
Juan Carlos De la Concepcion
Böke Lab
19 days ago
Exactly my thoughts re the "unbiased" QED 1% list- this analysis puts it on firmer footing. One thing not captured here is the prominence of well-established authors; that's what triggered me whether QED was really ranking the science OR influenced by signals assoc'd w/ scientific prominence- EB
add a skeleton here at some point
1
22
6
reposted by
Juan Carlos De la Concepcion
Gyana Prakash Mahapatra
20 days ago
Excited to share our new preprint! How does the cyanobacterial hydrogenase HoxEFUYH drive photosynthetic H₂ production? Using
#cryoEM
, biochemistry, FTIR and EPR spectroscopy, we reveal its molecular mechanism, including the basis of electron bifurcation/confurcation.
www.biorxiv.org/content/10.6...
loading . . .
Electron confurcation drives photosynthetic H2 production in cyanobacteria
Cyanobacteria are major contributors to global photosynthesis and are intensively studied for sustainable green H2 production. Central to this process is the bidirectional [NiFe]-hydrogenase HoxEFUYH,...
https://www.biorxiv.org/content/10.64898/2026.06.25.734504v1
1
11
10
Load more
feeds!
log in