Sophia Paul
@sophia-pa.bsky.social
📤 28
📥 15
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reposted by
Sophia Paul
Schuller Jan
4 months ago
Proud to present the lab's latest work. The full structure of the sodium translocating methyltransferase (Mtr) bound to a small oxygen-responsive small protein MtrI. Work by Tristan and together with
@schmitzstreitslab.bsky.social
.
www.biorxiv.org/content/10.1101/2025.06.02.657420v1
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reposted by
Sophia Paul
Schuller Jan
5 months ago
One of the largest open questions in anaerobic metabolism solved. The best work of my lab yet, performed by the incredible hard working, talented and motivated coworkers:
@fidelormz.bsky.social
,
@sophia-pa.bsky.social
and
@rnfr2d2.bsky.social
. I am a proud PI today!
www.nature.com/articles/s41...
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Structure of the ATP-driven methyl-coenzyme M reductase activation complex - Nature
The structure and function of the MCR activation complex from Methanococcus maripaludis were revealed, demonstrating its ATP-dependent ability to activate MCR and form methane while uncovering a uniqu...
https://www.nature.com/articles/s41586-025-08890-7
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I am incredibly excited to share my first-ever research paper that has just been published in Nature! I thank my fellow co-first authors
@fidelormz.bsky.social
and
@rnfr2d2.bsky.social
and
@schullerjm.bsky.social
for leading this project.
www.nature.com/articles/s41...
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Structure of the ATP-driven methyl-coenzyme M reductase activation complex - Nature
The structure and function of the MCR activation complex from Methanococcus maripaludis were revealed, demonstrating its ATP-dependent ability to activate MCR and form methane while uncovering a uniqu...
https://www.nature.com/articles/s41586-025-08890-7
5 months ago
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reposted by
Sophia Paul
Anuj
5 months ago
For decades, how methanogenic archaea activate the MCR complex to produce methane remained a mystery. Today in Nature, we report the high-resolution cryo-EM structure of the MCR activation complex!
www.nature.com/articles/s41...
loading . . .
Structure of the ATP-driven methyl-coenzyme M reductase activation complex - Nature
The structure and function of the MCR activation complex from Methanococcus maripaludis were revealed, demonstrating its ATP-dependent ability to activate MCR and form methane while uncovering a uniqu...
https://www.nature.com/articles/s41586-025-08890-7
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