Excited to share our new preprint! How does the cyanobacterial hydrogenase HoxEFUYH drive photosynthetic H₂ production? Using #cryoEM, biochemistry, FTIR and EPR spectroscopy, we reveal its molecular mechanism, including the basis of electron bifurcation/confurcation. www.biorxiv.org/content/10.6...

Now online with @natcomms.nature.com 🤩 doi.org/10.1038/s414...

How do “LEGO-like” electron-bifurcating modules combine to drive degradation in BTEX-contaminated ecosystems? Check out our latest preprint, where we use cryo-EM and cryo-ET to reveal how the 1 MDa BCRII complex powers extremely endergonic aromatic ring reduction. www.biorxiv.org/content/10.6...

1/ Excited to share our preprint! 🥳 Degradation of aromatic compounds, including BTEX pollutants, requires highly endergonic aromatic ring reduction. Using #cryoEM and in situ #cryoET, we show how BCRII couples electron bifurcation modules in one giant redox machine www.biorxiv.org/content/10.6...

Congratulations to @rnfr2d2.bsky.social for winning the GBM #PhDAward! Very well deserved- You put in so much hard work to get here. So happy and proud to see you succeed

Our latest work on the nitrogenase-like methylthio-alkane reductase, which specifically reduces reduces carbon-sulfide bonds is now out @natcatal.nature.com: doi.org/10.1038/s419.... We find for the first time large #nitrogenase metalloclusters (P- and L-cluster) outside nitrogenases.

Have you ever looked at the night sky and wondered if there’s a chlorophyll f in the reaction centre of Photosystem I from far-red light adapted cyanobacteria? 🦠 Well, we did (don’t judge) and the work that followed is now out as a First Release in @science.org www.science.org/doi/10.1126/...

Proud to present the lab's latest work. The full structure of the sodium translocating methyltransferase (Mtr) bound to a small oxygen-responsive small protein MtrI. Work by Tristan and together with @schmitzstreitslab.bsky.social . www.biorxiv.org/content/10.1101/2025.06.02.657420v1

One of the largest open questions in anaerobic metabolism solved. The best work of my lab yet, performed by the incredible hard working, talented and motivated coworkers: @fidelormz.bsky.social , @sophia-pa.bsky.social and @rnfr2d2.bsky.social. I am a proud PI today! www.nature.com/articles/s41...

I am incredibly excited to share my first-ever research paper that has just been published in Nature! I thank my fellow co-first authors @fidelormz.bsky.social and @rnfr2d2.bsky.social and @schullerjm.bsky.social for leading this project. www.nature.com/articles/s41...

For decades, how methanogenic archaea activate the MCR complex to produce methane remained a mystery. Today in Nature, we report the high-resolution cryo-EM structure of the MCR activation complex! www.nature.com/articles/s41...