Molecular evolution of the Wood-Ljungdahl pathway and the reductive glycine pathway in Desulfobacterota www.frontiersin.org/journals/mic... #jcampubs

Last Friday was the defense of my PhD thesis entitled "Structural basis of anaerobic enzymes mediated by noncanonical metalloclusters" after 4 yrs at the @synmikro.bsky.social 🎓🎓 Big thanks to my supervisor @schullerjm.bsky.social and the whole Schuller lab for their continuous and massive support!

Nickel: Geochemistry, biochemistry and its role in chemical and biological evolutions www.sciencedirect.com/science/arti...

Carbon-monoxide-driven bioethanol production operates through a tungsten-dependent catalyst #BioEthanol #CarbonMonoxide www.nature.com/articles/s41...

Our latest work on the nitrogenase-like methylthio-alkane reductase, which specifically reduces reduces carbon-sulfide bonds is now out @natcatal.nature.com: doi.org/10.1038/s419.... We find for the first time large #nitrogenase metalloclusters (P- and L-cluster) outside nitrogenases.

Happy to share our latest review article, this time joining forces with 📌Seigo Shima, 📌James Birrell, 📌Giorgio Caserta, and 📌Oli Lenz. We wrote about hydrogenase catalysis because this is what we do best 😎 doi.org/10.1002/9783...

#Methanosarcina acetivorans requires methanol:coenzyme M methyltransferases for #ethane formation from ethanol #methane link.springer.com/article/10.1...

New frontiers in short-chain alkyl-coenzyme M reductases #methanogenesis #methane #microbiology www.sciencedirect.com/science/arti...

Carbon monoxide metabolism in freshwater anaerobic methanotrophic archaea https://www.biorxiv.org/content/10.1101/2025.09.16.676500v1

Atomic resolution structures of the methane-activating enzyme in anaerobic methanotrophy reveal extensive post-translational modifications #microbiology #methane #archaea @natcomms.nature.com www.nature.com/articles/s41...

Fantastic review on methodological developments in protein structural phylogenetics academic.oup.com/gbe/article/...

Stepwise and reversible assembly of [2Fe–2S] rhombs to [8Fe–8S] clusters (Mougel et al. via @natchem.nature.com) www.nature.com/articles/s41...

1/3 Electricity from air! In the top journal Nano Energy today, we report the first fuel cell that makes power from air alone. We achieved this by using the enzyme Huc to oxidize ambient hydrogen. This results in a continuous low-level power from air and higher outputs with industrial waste gases.

Metal ions are universally required for life, and many of the foundational principles of metal homeostasis have emerged from studies of microbial systems. In this review, I provide a introductory overview targeted to those new to the field. #MicroSky #Metals rdcu.be/eycU2

Our new study shows how nickel limitation changes electron flow in methanogens. @nature.com #methanogens #methane #archaea www.nature.com/articles/s41...

New paper from the lab from Sriram Garg in my group. We introduce a general substitution matrix for structural phylogenetics. I think this is a big deal, so read on below if you think deep history is important. academic.oup.com/mbe/advance-...

Proud to present the lab's latest work. The full structure of the sodium translocating methyltransferase (Mtr) bound to a small oxygen-responsive small protein MtrI. Work by Tristan and together with @schmitzstreitslab.bsky.social . www.biorxiv.org/content/10.1101/2025.06.02.657420v1

CLUSTERING FOR METHANE Nice write-up @natcatal.nature.com of our recent article on MCR activation 🙏🏻 www.nature.com/articles/s41...

Leveraging spectroscopic and structural approaches we obtained new insights into the role of #ferredoxins in N2 fixation. Just published in Chemistry – A European Journal: doi.org/10.1002/chem...! Great work by Holly Addison. Fantastic collaboration with Antonio Pierik on the EPR characterization.

Happy to present the lab latest work, today from the green-side. The ultimate PSII assembly intermediate that directly precedes incorporation of the Mn4O5Ca cluster and formation of the OEC. Psb32 binds to PsbV, challenging the assumption the extrinsic subunits all associate spontaneously in-vivo.

My lab mates and their collaborators have a really cool paper you should check out: the structure of catalytically active (Ni(I)) methyl-coM reductase: www.biorxiv.org/content/10.1...

Short press piece @unipotsdam.bsky.social about our new article @nature.com on methyl coenzyme M reductase (MCR) www.uni-potsdam.de/en/headlines...

🧪 Durchbruch in der biochemischen Grundlagenforschung mit zentraler Bedeutung für #Energie & #Klima: Ein Team der @unimarburg.bsky.social & der #TUBerlin/ @unisyscat.bsky.social hat erstmals den Aktivierungsmechanismus des Enzyms MCR aufgeklärt – zentral für die biologische Produktion von #Methan. 👇

I'm truly excited to announce our new publication in @nature.com unraveling a central picture of the Methyl-coenzyme M reductase (MCR) activation machinery and it's strong ATP dependency - kudos to @rnfr2d2.bsky.social for the fantastic illustration! LINK: www.nature.com/articles/s41...