Very cool story about the efficient transport and incorporation of non canonical amino acid!

Our latest work on the nitrogenase-like methylthio-alkane reductase, which specifically reduces reduces carbon-sulfide bonds is now out @natcatal.nature.com: doi.org/10.1038/s419.... We find for the first time large #nitrogenase metalloclusters (P- and L-cluster) outside nitrogenases.

Fantastic work by the Ward lab to repurpose cytochrome #P450 enzymes for a new-to-nature asymmetric metal-catalysed H atom transfer! Just released @Nature : doi.org/10.1038/s415.... A must read!🧪

Great collaboration with @lennartschada.bsky.social on an #enzyme converting the #plastic component ethylene glycol and to a feedstock chemical for microbes. Offering new ways to use plastic biotechnologically. 🧪

I am honored and excited that our research on #nitrogenases and the conversion of #CO2 to hydrocarbons is highlighted in the Yearbook 2024 of the Max Planck Society, see page 29. An English and a German version of the Yearbook are available in www.mpg.de/13631298/yea....

A must read for anybody interested in the evolution of life and how to construct phylogenies using structures. Outstanding work by @georghochberg.bsky.social and co-worker. Congrats!

New paper from the lab from Sriram Garg in my group. We introduce a general substitution matrix for structural phylogenetics. I think this is a big deal, so read on below if you think deep history is important. academic.oup.com/mbe/advance-...

Leveraging spectroscopic and structural approaches we obtained new insights into the role of #ferredoxins in N2 fixation. Just published in Chemistry – A European Journal: doi.org/10.1002/chem...! Great work by Holly Addison. Fantastic collaboration with Antonio Pierik on the EPR characterization.

Marburg rules. I see @rebeleinlab.bsky.social @schullerjm.bsky.social @georghochberg.bsky.social in the crowd 😘

Out now in @chemicalscience.rsc.org: We apply 2DIR spectroscopy to study [FeFe] hydrogenase for the first time. Check it out! pubs.rsc.org/en/content/a...

The National Climate Assessment — already in the works for months — was gutted earlier this week, when President Trump’s administration dismissed hundreds of scientists working on it.. The National Nature Assessment was cancelled on his first day back in office.. 🧪🦠 www.nature.com/articles/d41...

I think a lot about what Carl Sagan said in one of his final interviews.

*** Only a few days left to apply *** Postdoc position at the University of Marburg (Germany), funded within our ERC Advanced Grant "C-SWITCH" Spatiotemporal regulation of cellular processes by CTP-switches in bacteria Apply by 04 May: stellenangebote.uni-marburg.de/jobposting/2...

My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑‍🎓 Please RT. It's a great place with world-class expertise in all sorts of biomedical & biological engineering topics like synthetic biology. It's also not in the USA. www.imperial.ac.uk/jobs/search-...

Exciting work from @frunzkelab.bsky.social and @borjana-a.bsky.social at @fz-juelich.de

New preprint from @erdrich-science.bsky.social of our collaborative project with @borjana-a.bsky.social, @fz-juelich.de and @guidogrossmann.bsky.social @hhu.de: "Phage biocontrol reduces the burden on plant immunity through suppression of bacterial virulence" www.biorxiv.org/content/10.1...

Exciting work by Ribbe & Hu lab demonstrating the in vivo reduction of N2 by L-cluster containing Nif(EN)2 inside E. coli: www.science.org/doi/10.1126/... This finding suggests a smaller minimal gene set for the heterologous expression of #nitrogenase and an easier route to synthetic #N2-fixation

Great work Adrian!

Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research www.nature.com/articles/s41... #jcampubs

Gab es dazu wirklich KEINE Berichterstattung? Eine Google-News Suche zu CO2-Konzentration liefert nur Ergebnisse zu einem UN-Bericht aus 2024. Keine Studie, keine News? Außer natürlich bei BIP, Inflation, Arbeitslosigkeit... 😬 Bitte gerne Links darunter posten.

Energy from air? No problem! In our new preprint, we reconstitute the machinery that allows microbes to endure starvation. By using the trace amounts of hydrogen in air alone, they produce plenty of chemical energy (2 ATP) to get by. The only byproduct? Water. www.biorxiv.org/content/10.1...

Towards community-driven visual proteomics! Excited to finally share this large-scale curated & annotated dataset of 1829 high-quality #cryoET tomograms of the little green alga that just keeps giving— Chlamydomonas! 🧪🧶🧬🌾🌊🌍 Preprint📜: www.biorxiv.org/content/10.1... A short thread🧵👇

One of the largest open questions in anaerobic metabolism solved. The best work of my lab yet, performed by the incredible hard working, talented and motivated coworkers: @fidelormz.bsky.social , @sophia-pa.bsky.social and @rnfr2d2.bsky.social. I am a proud PI today! www.nature.com/articles/s41...

This is an excellent explanation about the implications of finding #nitrogenase #metalloclusters in the MCR activation complex

I'm truly excited to announce our new publication in @nature.com unraveling a central picture of the Methyl-coenzyme M reductase (MCR) activation machinery and it's strong ATP dependency - kudos to @rnfr2d2.bsky.social for the fantastic illustration! LINK: www.nature.com/articles/s41...

Structure of the ATP-driven methyl-coenzyme M reductase activation complex pubmed.ncbi.nlm.nih.gov/40240609/ #cryoem

Had a blast at VAAM 2025 in Bochum @vaam-microbes.bsky.social. Holly Addison and Frederik Schmidt gave fantastic talks about our work electron transport to #nitrogenase and nitrogenase #catalysis

Forgot to tag @jamesbirrell.bsky.social‼️

Very proud to see my first PhD student defend his thesis @mpimicrobiomarburg.bsky.social ! Congrats to Leonard Ernst 🎊🍾🎉🥳

Ten simple rules for developing good reading habits during graduate school and beyond To me, the most important are: Read often, read broadly (incl. older papers and outside your field), and learn to read some papers in detail and others more superficially (and quickly)

Come and join us in Marburg

www.nature.com/articles/s41... They "identified many highly conserved positions that tolerate mutation and rare mutations that improve CO2 affinity. These data indicate that non-trivial biochemical changes are readily accessible" #PlantScience

Two exciting papers about the the protection of nitrogenases from O2 by the ferredoxin Shethna protein II from the Tezcan doi.org/10.1038/s415... and Einsle doi.org/10.1038/s415... labs were published today by @nature.com. Surprisingly both papers reveal superstructures of nitrogenase filaments.

I'll never understand how bottom trawling is legal. 🌊 www.nature.com/articles/s41...

I am honored to be selected as EMBO Young Investigator 2024. Thank you to my students, lab members and collaborators who made this success possible! www.embo.org/press-releas...