Why are α-synuclein aggregates in Parkinson’s disease (PD) toxic at the cell biological level? Our new study shows that α-syn fibrils hijack the ESCRT membrane repair system, triggering a feedback loop that worsens aggregation. You can find it at: authors.elsevier.com/sd/article/S...

We are looking for a Veterinary Doctor (M/F/D) with a PhD to be the Head of the central animal husbandry. If this position speaks to you, we are happy to receive your application: ❕Apply until: October 12 ❕ www.mpg.de/25383453/pro... #hiring #jobalert #VeterinaryDoc #Vet #veterinary

We are looking forward to welcoming you in Martinsried! More details (in German) : mpi.lineupr.com/tdot/

We are looking for a Systemadministrator (M/F/D) Linux/Storage. If you are interested in working within a challenging and bespoke infrastructure, we await your application! ❕ Apply until: October 5 ❕ www.linkedin.com/jobs/view/42... #hiring #jobalert #systemadministrator #Adminjob

You like buying products and services for scientific purposes? You know the market inside out? Then apply for our opening as Purchaser (M/F/D)! ❕ Apply until: October 8 ❕ recruitingapp-5446.de.umantis.com/Vacancies/56... #hiring #jobalert #purchaser #procurement #buying

We are hiring an IT-Expert (M/F/D) who will conceptualize, develop and work on our IT Infrastructure. If you want to bring your tech skills into a scientific environment, apply under the link below. ❕ Apply until: October 5 ❕ lnkd.in/ewjkC9Hv #hiring #jobalert #ITjobs #HPC #Infrastructure

Structural & functional analysis revealed that the extracellular #chaperone #clusterin functions through two tails in preventing protein aggregation. ❕Paper: www.nature.com/articles/s41... ❕Press Release: www.biochem.mpg.de/structure-of... #Alzheimers @natsmb.nature.com @pyustecheca.bsky.social

We are looking for a Technical Assistant (BTA, CTA, MTA) for our Research Department Totipotency. Feel free to apply if this position speaks to you. ❕ Apply until: October 15 ❕ www.mpg.de/25289190/tec... #hiring #jobalert #biochemistry #laboratory

#pictureofthemonth: Nr5a2 is a pioneer factor that controls activation of the #genome at the beginning of life. The illustration depicts this process. More: www.biochem.mpg.de/hooking-an-a... September – institute calendar of @mpibiochem.bsky.social & @mpiforbi.bsky.social Image: Wataru Kobayashi

We are looking forward to our joint event.

Congratulations Maria Wahle on your #PhD🎉. We wish you every success in your future career. @mannlab.bsky.social @mariawahle.bsky.social @imprs-ml.bsky.social

Do you love the world of science? Are you a passionate communicator eager to engage others? Put your talents to work as Head of Communications and Social Media in the #PublicRelations team! ❕Apply until: September 19 ❕https://www.mpg.de/25248300/head-of-communications-and-social-media #hiring

We are looking for an Employee for Dangerous Goods and Hazardous Substances Management to support our #EHS team, starting as soon as possible. ❕Apply until September 5 ❕https://www.mpg.de/25220494/mitarbeiter-m-w-d-fuer-gefahrgut-und-gefahrstoffmanagement #hiring #jobalert

#pictureofthemonth: Pairs of white-browed coucals often duet. Here you see a coucal listening to a playback recording of its own species. Find out more: www.bi.mpg.de/goymann August – Institute calendar of @mpibiochem.bsky.social and @mpiforbi.bsky.social Picture by @dudumizi.bsky.social

Ever wondered what happens when therapeutic antibodies bind to cancer cells? In our latest study, we used multiplexed 3D-RESI to directly visualize how anti-CD20 antibodies interact with their receptors, revealing their precise arrangement at single-protein resolution. (1/6)

You want to head up the newly established Lentiviral Core Facility? We are looking for a qualified and motivated Application Scientist, part-time 50%. ❕apply until July 25 ❕https://www.mpg.de/25024724/application-scientist-m-f-d-part-time-50 #hiring #sciencejobs #applicationscientist #Lentivirus

#pictureofthemonth: Illustration of the read-write mechanism by which ubiquitin tags are placed on histone H2A along genes to influence their expression. More: www.biochem.mpg.de/painting-gen... July – institute calendar of @mpibiochem.bsky.social and @mpiforbi.bsky.social Image by Tamara Bäßler

Our Grants Office is seeking full-time or part-time (min. 29 h/ week) support for the administrative project management of over 30 externally funded research projects. ❕Apply until July 25 ❕https://www.mpg.de/24950578/scientific-coordinator-2025-17 #scienceadminstration #hiring #sciencecoordinator

Interested in translational, cutting-edge proteomics to redefine how we treat inflammatory skin diseases? The Nordmann-Lab, is looking for a postdoctoral fellow. Ready to join? ❕apply until July 23 ❕https://www.mpg.de/24950076/postdoctoral-position #Postdoc #jobsinscience @tnordmann.bsky.social

Congratulations to Ralf on your election as a new EMBO member: ❕Original press release from @embo.org : www.embo.org/press-releas...

🎉 Congratulations to Matthias Mann on 20 years leading Proteomics & Signal Transduction at MPI of Biochemistry! Two decades of groundbreaking mass spectrometry research and training excellent future scientists. #MS #Proteomics #Science @mannlab.bsky.social

An interdisciplinary study uncovers how benign borderline ovarian tumors develop into invasive low-grade serous carcinoma, opening a new avenue for targeted therapy. ❕Publication: www.cell.com/cancer-cell/... ❕Press Release: www.biochem.mpg.de/when-tumors-...

After many hours in the lab and tackling tricky research questions, it's now time to celebrate. 🥳 Congratulations on your PhD, Vincent @mannlab.bsky.social‬. We wish you every success in your future career.

Upcoming Joint IMPRS lecture with Pablo Oteiza tomorrow! The talk is free for everyone, on campus or via zoom. More info: imprs-bi.mpg.de/68666/Joint_... @mpibiochem.bsky.social @imprs-ml.bsky.social

A warm welcome to @schullerm.bsky.social! We wish you and your new research group every success. ❕Press Release: www.biochem.mpg.de/marion-schul... ❕Website: www.biochem.mpg.de/schuller #LiseMeitner Research Group, #bacteriophages, #ADPribosylation signalling, #StructuralBiology

PhD Position in molecular mechanisms of ADP-ribosylation in the conflict between phages and the bacterial host. The 'Host Defence Mechanisms' group led by Marion Schuller is looking to recruit a #PhD student (m/f/d) with a proposed start date of September 2025

Upcoming Joint IMPRS Lecture with Karl Duderstadt @duderstadtlab.bsky.social from the @mpibiochem.bsky.social this Thursday, 12 June at 4 pm CET via Zoom! More info: imprs-ml.mpg.de/38279/Joint-... @mpibiochem.bsky.social @mpiforbi.bsky.social @tum.de @lmumuenchen.bsky.social

#pictureofthemonth: These two ruff chicks are just three days old. Which one fledges earlier and which one grows faster? These are exciting questions to study! More infos: www.bi.mpg.de/kuepper June – Institute calendar of @mpibiochem.bsky.social and @mpiforbi.bsky.social

Congratulations! The #ShawPrize in Life Science & Medicine 2025 is awarded to Wolfgang Baumeister for his pioneering development & use of cryo-ET. ❕https://www.shawprize.org/laureates/2025-life-science-medicine/ #CryoEM #cryoET #Award

Check out our latest study @natsmb.nature.com‬: Establishing a consensus model for #ubiquitin chain assembly by HECT #E3 ligases: #cryoEM structures of #TRIP12 forming K29-linked and K29/K48-branched chains! ❕ www.nature.com/articles/s41... @samuelmaiwald.bsky.social @unileiden.bsky.social

Can we build synthetic cells from de novo designed proteins? Find out more in the latest review @natrevbioeng.nature.com from Bela Frohn, Shunshi Kohyama and Petra Schwille. ❕Publication: doi.org/10.1038/s442... #ProteinDesign #SyntheticBiology @belafrohn.bsky.social ‬

John Briggs has been elected to the Fellowship of the Royal Society, the UK’s national academy of sciences. Congratulations to him and the other outstanding researchers from across the world! ❕https://royalsociety.org/news/2025/05/new-fellows/ @briggsgroup.bsky.social ‪@royalsociety.org

Elena Conti @mpibiochem.bsky.social and Jörn Piel @ethz.ch have been awarded the Jung Prize for Medicine 2025. We congratulate them and all other #award winners. ❕https://www.biochem.mpg.de/elena-conti-erhaelt-renommierten-jung-preis-fuer-medizin?c=569499 ❕https://jung-stiftung.de/

#pictureofthemonth: Proteins in our cells are interconnected. The illustration shows the connections each protein has with an average of 16 others. More: www.biochem.mpg.de/mann May – institute calendar of @mpibiochem.bsky.social and @mpiforbi.bsky.social Image by @sci-illustrate.bsky.social

Since April, @tnordmann.bsky.social has been leading a research Group @mpibiochem.bsky.social. He has now been awarded the prestigious Oscar Gans Prize by the German Dermatological Society. Congratulations and welcome! #award #dermatology #proteomics @mannlab.bsky.social

Our directors Elena Conti @labconti.bsky.social and Matthias Mann @mannlab.bsky.social have been elected to the prestigious U.S. National Academy of Sciences. Congratulations! ❕https://www.nasonline.org/news/2025-nas-election/ @nasonline.org #nasmembers

Check out our new review discussing novel immunometabolic mechanisms underlying inflammation, metabolomic techniques and potential metabolite biomarkers of chronic inflammatory disease! Special focus is on #efferocytosis #IL-10 and #trainedimmunity link.springer.com/article/10.1...

Want to work in science management join the Career Development Team | IMPRS-ML at the @mpibiochem.bsky.social? Then check out our latest job offer "Coordinator (m/f/div) (maternity cover)" and apply via the online portal by 23 May! 🚀 recruitingapp-5446.de.umantis.com/Vacancies/54...

Lassen Sie sich für Wissenschaft begeistern: Im nächsten Vortrag unserer allgemeinverständlichen Reihe "Was Wissen schafft" gibt Tobias Bonhoeffer spannende Einblicke in sein Forschungsfeld Lernen und Vergessen. 🗓️ 6. Mai um 19:00 Uhr 📍 Hybrid, in Martinsried oder per Zoom 🌐 www.bi.mpg.de/wws

Scientists @mannlab.bsky.social, at Pavel Strnad Lab at UniklinikAachen & at Alksander Krag Lab at OUH Odense Universitetshospital, Svendborg Sygehus have used spatial #DeepVisualProteomics to reveal how liver cells become sick in patients with the proteotoxic disease alpha-1 antitrypsin deficiency.

Where do #proteins go in cells? Next-generation methods map the molecules’ hidden lives! Spatial #proteomics at the lab of Matthias Mann @mpibiochem.bsky.social is helping biologists to uncover how cells work by mapping where proteins operate.😊 nature.com/articles/d41... #cellbiology @nature.com

Upcoming joint IMPRS lecture: Nadine Gogolla, director @mpi-psychiatry.bsky.social, will speak on dissecting the neural circuits of emotion. The talk is free for everyone, on campus or via zoom! More information: imprs-bi.mpg.de/68666/Joint_... @imprs-ml.bsky.social @mpibiochem.bsky.social

#pictureofthemonth: Using a fluorescent marker, the direction-selective neurons become visible under a microscope - even through the chitin exoskeleton of a fruit fly's head! Read more: www.bi.mpg.de/borst April – Institute calendar of @mpibiochem.bsky.social & @mpiforbi.bsky.social 📸 Eleni Samara

Congratulations! Dr. Zebin Tong from our Schulman lab & Dr. Adam Mamot @SchwilleLab have been awarded the prestigious MSCA Fellowship for outstanding research projects on GP78 Ubiquitin E3 Ligase (Zebin) and Gene Self-Expression (Adam). ❕ marie-sklodowska-curie-actions.ec.europa.eu/news/msca-aw...

Our Lise Meitner Research Group Leader Maria Sokolova receives this year's Heinz Maier-Leibnitz Prize 2025 for her outstanding research on bacteriophages. Congratulations!🥳 ❕ www.dfg.de/de/service/p... #Award, #WomenInScience, #bacteriophages @arimiora.bsky.social @maxplanck.de

Scientists from the Schulman-Lab and James-Lab @mrclmb.bsky.social developed the new technology #UbiREAD to decipher the intricacies of the #proteindegradation code within cells. ❕Publication: @cp-molcell.bsky.social: bit.ly/4iZ0Fhe ❕Press Release: bit.ly/4bXt6K7 @leokiss.bsky.social #ubiquitin

Are you interested in gaining an insight into the activities of the Career Development Service and our IMPRS-ML PhD programme? Apply for an internship! ❕ Apply until April 1 ❕https://lnkd.in/dVDupGgy #hiring #jobalert #joboffers #stellenausschreibung #socialmedia @imprs-ml.bsky.social

Join us as a Proteomics & Mass Spectrometry Scientist and provide expert support to your customers for complex proteomics projects. Take a look at the #joboffer ❕apply until April 4 ❕http://mpg.de/24313276/proteomics-mass-spectrometry-scientist #hiring #jobalert #JobInScience #proteomics

Looking forward to diving deep into the world of #RNAbindingproteins (RBPs) at the EMBL Conference that starts today! 🎙️ Keynote lectures today by ▫️ Elena Conti on mRNA-binding proteins ▫️ Anthony Hyman @mpi-cbg.de on #PhaseSeparation & role of RBPs #EMBLRBP @events.embl.org

Upcoming Joint IMPRS Lecture with Andreas Pichlmair from the @tum.de this Thursday, 13 March at 4 pm CET! The talk is free for everyone, on campus or via Zoom. ↪️ More info: imprs-ml.mpg.de/38279/Joint-... @mpibiochem.bsky.social @mpiforbi.bsky.social @tum.de @lmumuenchen.bsky.social