Very proud of the work of Dana Moreno about statistical modelling of CDR3 sequences in TCR repertoires: www.biorxiv.org/content/10.6....

Nice results: rdcu.be/eTNVr. Looks like the decision to develop specific ML models of TCR-epitope interactions for each epitope was a reasonable choice.

For those who followed the IMMREP25 competition and are interested in understanding how specificity was encoded for each epitope, check our TCR Motif Atlas IMMREP25 page: tcrmotifatlas.unil.ch/Browse_epito...

Very happy to share our latest manuscript about TCR-epitope recognition specificity: www.biorxiv.org/content/10.1...

Cool paper on scRNA T cell annotation. However, a note for ProjecTILs users: I wouldn’t rely on the ProjecTILs benchmark in this work, as it was run using a mouse reference map to classify human T cells (even though human CD4/CD8 T cell maps are available github.com/carmonalab/P...)

Interested in unraveling specificity in epitope recognition by TCRs and KIRs in the context of graft-versus-host diseases. We have an open post-doc position in the group. Do not hesitate to share the word.

Happy to share the great work of Giancarlo Croce: Phage display enables machine learning discovery of cancer antigen–specific TCRs | Science Advances www.science.org/doi/10.1126/...

Call for abstract open at BC2 2025: bc2.ch/talks-poster...

Matei Teleman's SuperSpot paper out in Bioinformatics: academic.oup.com/bioinformati...