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Speakers include: @nozomi-ando.bsky.social @hkws.bsky.social, @pilarcossio.bsky.social, @cjjackson.bsky.social, @karsonchrispens.bsky.social, @alisiafadini.bsky.social, @thompson-lab.bsky.social, Joey Davis, Alex Bronstein, Rohith Krishna, Matthew McPartlon, Frederic Poitevin

Hosted in partnership with the DiffUSE Project! 🎉👇

Congrats to DiffUSE lead Stephanie Wankowicz @stephanieaw.bsky.social, on winning the inaugural Sheldrick Award! Her work on entropic flexibility and reproducibility in structural biology is core to what we're building. #crystallography #structuralbiology #openscience aucryst.org/sheldrick-aw...

We observed a tradeoff: weak guidance improves fit to data without wrecking protein geometry. But strong guidance destroys the geometry. Interestingly, models differ a lot in how they handle this despite similar architectures.

Excited to share Sampleworks led by @karsonchrispens.bsky.social with @diffuseproject.bsky.social. It's a modular framework connecting structure predictors to experimental data and guidance methods. Swap predictors or guidance methods. All open and made to be built upon. t.co/fvNHH3gfVu

Radial is live! A new organization at @asterainstitute.bsky.social bringing together structural biologists, engineers, and ML scientists to redesign how we do science. @statnews.com has the story: www.statnews.com/2026/03/11/r...

MD simulations show that diffuse scattering patterns shift depending on whether ligand or a buffer molecule occupies the binding pocket. The differences are quantitatively significant, a promising sign that experiments could detect these changes. Read more: diffuse.science/post/shake-i...

Tomorrow (2/27) 3 pm ET, DiffUSE Project Scientist Steve Meisburger presents "Diffuse Scattering Wars (Episode IV): A New Hope for Structural Biology" Learn how diffuse scattering could reveal what AI structure predictors are missing. Join here: www.chess.cornell.edu/science/ches...

The Diffuse Project is looking for an amazing Project Manager to help us achieve our goal of unlocking protein dynamics! Are you a scientist who naturally loves organization, coordination, problem solving and working with a diverse team of scientists & engineers?

Happy @diffuseproject.bsky.social launch day! Check out our latest effort. We're grappling with how to better understand protein dynamics and capture/share the information that would best allow the community to make use of that data. Take a look!

What’s the next PDB? Maybe it’s …the PDB. We just launched @diffuseproject.bsky.social a structural biology initiative exploring protein motion & rethinking how we generate and use experimental data. Quick 🧵👇 www.diffuse.science

Announcing the Diffuse Project! We're unlocking protein dynamics through diffuse X-ray scattering - the overlooked signal that could revolutionize how we understand protein motion. seemay.substack.com/p/from-syste...